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检索条件"机构=Biostat and Programming"
418 条 记 录,以下是141-150 订阅
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PHASE 1B DOSE-ESCALATION STUDY OF ZN-C3 (WEE1 INHIBITOR) WITH CHEMOTHERAPY IN PATIENTS WITH PLATINUM-RESISTANT OVARIAN, PERITONEAL, OR FALLOPIAN TUBE CANCER: ZN-C3 PLUS GEMCITABINE ARM
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INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER 2022年 32卷 A242-A242页
作者: Thaker, Premal Pasic, Anes Richardson, Gary Vranjes, Zivko Prather, Stanislava Makris, Lukas Misir, Soamnauth Pultar, Philippe Voliotis, Dimitris Fu, Siqing Washington Univ Div Gynecol Oncol Sch Med St Louis MO USA Univ Sarajevo Dept Oncol Clin Ctr Sarajevo Bosnia & Herceg Cabrini Hosp Malvern Med Oncol Melbourne Australia Univ Clin Ctr Republ Srpska Ctr Canc Banja Luka Bosnia & Herceg Zentalis Pharmaceut Clin Operat New York NY USA Zentalis Pharmaceut Biostat & Stat Programming New York NY USA Zentalis Pharmaceut Clin Dev New York NY USA Univ Texas MD Anderson Canc Ctr Invest Canc Therapeut Houston TX USA
TP039/#152
来源: 评论
Canadian Real-World Experience of Using Sacubitril/Valsartan in Patients With Heart Failure With Reduced Ejection Fraction: Insight From the PARASAIL Study
CJC OPEN
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CJC OPEN 2020年 第5期2卷 344-353页
作者: Haddad, Haissam Bergeron, Sebastien Ignaszewski, Andrew Searles, Gregory Rochdi, Driss Dhage, Priyanka Bastien, Natacha Univ Saskatchewan Dept Med Saskatoon SK Canada Univ Cardiol & Pneumol Quebec Ctr Rech Inst Dept Med Quebec City PQ Canada Univ British Columbia Dept Med Vancouver BC Canada St Johns Hosp Dept Med St John NB Canada Novartis Pharmaceut Canada Inc Med Affairs Dorval PQ Canada Novartis Pharmaceut Pvt Ltd Biostat & Stat Programming Hyderabad India Novartis Pharmaceut Canada Inc Med Affairs Dorval PQ Canada
Background: To determine the effectiveness of sacubitril/valsartan 97/103 mg twice daily (b.i.d.) on tolerability, safety, and quality of life (QoL) in Canadian patients with heart failure with reduced ejection fracti...
来源: 评论
Advancing therapy with iGlarLixi versus premix BIAsp 30 in basal insulin-treated type 2 diabetes: Design and baseline characteristics of the SoliMix randomized controlled trial
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DIABETES OBESITY & METABOLISM 2021年 第6期23卷 1221-1231页
作者: McCrimmon, Rory J. Al Sifri, Saud Emral, Rifat Mohan, Viswanathan Sauque-Reyna, Leobardo Trescoli, Carlos Lalic, Nebojsa Alvarez, Agustina Demil, Nacima Coudert, Mathieu Shaunik, Alka Bonnemaire, Mireille Rosenstock, Julio Univ Dundee Sch Med Div Syst Med Dundee Scotland Al Hada Mil Hosp At Taif Saudi Arabia Ankara Univ Dept Endocrinol & Metab Dis Fac Med Ankara Turkey Dr Mohans Diabet Special Ctr Chennai Tamil Nadu India Madras Diabet Res Fdn IDF Ctr Excellence Diabet Care Chennai Tamil Nadu India ICMR Ctr Adv Res Diabet Chennai Tamil Nadu India Inst Diabet Obesidad & Nutr SC Cuernavaca Morelos Mexico Hosp Univ La Ribera Alzira Spain Univ Belgrade Clin Ctr Serbia Fac Med Clin Endocrinol Diabet & Metab Dis Belgrade Serbia Sanofi Buenos Aires DF Argentina Sanofi Diabet Med Operat Dept Chilly Mazarin France Sanofi Biostat & Programming Dept Chilly Mazarin France Sanofi US Bridgewater NJ USA Sanofi Paris France Dallas Diabet Res Ctr Med City Dallas TX USA
Aim Premix insulin is commonly used in some regions of the world, despite the higher risk of hypoglycaemia and weight gain compared with basal insulin, based on the premise that it offers a simplified insulin regimen.... 详细信息
来源: 评论
Correlation between patient engagement with a digital medicine system and clinical symptom improvement
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EUROPEAN NEUROPSYCHOPHARMACOLOGY 2021年 53卷 S374-S374页
作者: Cochran, J. Fang, H. Le Gallo, C. Peters-Strickland, T. Lindenmayer, J. P. Fowler, J. C. Otsuka Pharmaceut Dev & Commercializat Inc Data Sci Med & Real World Data Analyt Princeton NJ USA Otsuka Pharmaceut Dev & Commercializat Inc Biostat Princeton NJ USA Otsuka Pharmaceut Dev & Commercializat Inc Clin Programming Princeton NJ USA Otsuka Pharmaceut Dev & Commercializat Inc Global Clin Dev Princeton NJ USA NYU Grossman Sch Med Dept Psychiat New York NY USA
P.0508
来源: 评论
A phase 2, open-label, single-arm, prospective, multi-center study of nab-sirolimus plus letrozole in advanced or recurrent endometrioid endometrial cancer
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INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER 2023年 第SUPPL_4期33卷 A249-A250页
作者: Dockery, Lauren Priebe, Anna Duska, Linda Green, Angela Mathews, Cara Musa, Fernanda O'Malley, David Puechl, Allison Ding, Li Schmid, Anita Navarro, Willis Slomovitz, Brian Moore, Kathleen Oklahoma Univ Hlth Stephenson Canc Ctr Gynecol Oncol Oklahoma City OK USA Texas Oncol Tyler TX USA Univ Virginia Charlottesville VA USA Mem Sloan Kettering Canc Ctr New York NY USA Women & Infants Hosp Rhode Isl Providence RI USA Swedish Canc Inst Seattle WA USA Ohio State Comprehens Canc Ctr Dept Obstet & Gynecol Columbus OH USA Atrium Hlth Gynecol Canc Levine Canc Inst Charlotte NC USA Aadi Biosci Biostat Programming & Data Management Pacific Palisades CA USA Aadi Biosci Clin Sci Pacific Palisades CA USA Aadi Biosci Clin Dev & Pharmacovigilance Pacific Palisades CA USA Mt Sinai Med Ctr Gynecol Oncol Miami Beach FL USA
TP009
来源: 评论
Exposure-Response Analyses and Disease Modeling for Selection and Confirmation of Optimal Dosing Regimen of Isatuximab in Combination Treatment in Patients with Multiple Myeloma
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BLOOD 2019年 134卷 1897-1897页
作者: Rachedi, Fatiha Koiwai, Kimiko Gaudel-Dedieu, Nadia Sebastien, Bernard Thai, Hoai-Thu El-Cheikh, Raouf Brillac, Claire Fau, Jean Baptiste Nguyen, Laurent Liu, Li Campana, Frank van de Velde, Helgi Veyrat-Follet, Christine Semiond, Dorothee Sanofi Translat Med & Early Dev Paris France Sanofi Biostat & Programming Bridgewater NJ USA Sanofi Oncol Cambridge MA USA
1897
来源: 评论
PCSK9 inhibition in patients with and without prior myocardial infarction or ischemic stroke: A pooled analysis of nine randomized-controlled studies of alirocumab
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JOURNAL OF CLINICAL LIPIDOLOGY 2019年 第3期13卷 443-454页
作者: Bruckert, Eric Kereiakes, Dean J. Koren, Michael J. Louie, Michael J. Letierce, Alexia Miller, Kathryn Cannon, Christopher P. Grp Hosp Pitie Salpetriere Serv Endocrinol Metab & Prevent Malad Cardiovasc Paris France Christ Hosp Lindner Res Ctr Heart & Vasc Ctr Cincinnati OH 45219 USA Jacksonville Ctr Clin Res Jacksonville FL USA Regeneron Pharmaceut Inc 777 Old Saw Mill River Rd Tarrytown NY 10591 USA Sanofi Biostat & Programming Chilly Mazarin France Regeneron Pharmaceut Inc Biostat & Data Management 777 Old Saw Mill River Rd Tarrytown NY 10591 USA Harvard Clin Res Inst Prevent Cardiol Sect Boston MA USA
BACKGROUND: Patients with prior cardiovascular events are at very high risk of recurrent events and may benefit from low-density lipoprotein cholesterol (LDL-C) lowering beyond that achieved with maximally tolerated s... 详细信息
来源: 评论
Ketolysis drives CD8+T cell effector function through effects on histone acetylation
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IMMUNITY 2023年 第9期56卷 2021-+页
作者: Luda, Katarzyna M. Longo, Joseph Kitchen-Goosen, Susan M. Duimstra, Lauren R. Ma, Eric H. Watson, McLane J. Oswald, Brandon M. Fu, Zhen Madaj, Zachary Kupai, Ariana Dickson, Bradley M. DeCamp, Lisa M. Dahabieh, Michael S. Compton, Shelby E. Teis, Robert Kaymak, Irem Lau, Kin H. Kelly, Daniel P. Puchalska, Patrycja Williams, Kelsey S. Krawczyk, Connie M. Levesque, Dominique Boisvert, Francois-Michel Sheldon, Ryan D. Rothbart, Scott B. Crawford, Peter A. Jones, Russell G. Van Andel Inst Dept Metab & Nutr Programming Grand Rapids MI 49503 USA Univ Copenhagen Novo Nord Fdn Ctr Basic Metab Res Blegdamsvej 3B DK-2200 Copenhagen Denmark Van Andel Inst Bioinformat & Biostat Core Grand Rapids MI 49503 USA Van Andel Inst Dept Epigenet Grand Rapids MI 49503 USA Univ Penn Perelman Sch Med Cardiovasc Inst Philadelphia PA 19104 USA Univ Penn Perelman Sch Med Dept Med Philadelphia PA 19104 USA Univ Minnesota Dept Med Div Mol Med Minneapolis MN 55455 USA Univ Sherbrooke Dept Anat & Cell Biol Sherbrooke PQ J1E 4K8 Canada Van Andel Inst Mass Spectrometry Core Grand Rapids MI 49503 USA Univ Minnesota Dept Biochem Mol Biol & Biophys Minneapolis MN 55455 USA
Environmental nutrient availability influences T cell metabolism, impacting T cell function and shaping immune outcomes. Here, we identified ketone bodies (KBs)-including j3-hydroxybutyrate (j3OHB) and acetoacetate (A... 详细信息
来源: 评论
Hypothesis tests for stratified mark-specific proportional hazards models with missing covariates, with application to HIV vaccine efficacy trials
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BIOMETRICAL JOURNAL 2018年 第3期60卷 516-536页
作者: Sun, Yanqing Qi, Li Yang, Guangren Gilbert, Peter B. Univ North Carolina Charlotte Dept Math & Stat Charlotte NC 28223 USA Sanofi Biostat & Programming Bridgewater MA 08807 USA Jinan Univ Sch Econ Dept Stat Guangzhou Guangdong Peoples R China Univ Washington Dept Biostat Seattle WA 98109 USA Fred Hutchinson Canc Res Ctr Seattle WA 98109 USA
This article develops hypothesis testing procedures for the stratified mark-specific proportional hazards model with missing covariates where the baseline functions may vary with strata. The mark-specific proportional... 详细信息
来源: 评论
Comparing Two Tests for Two Rates
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AMERICAN STATISTICIAN 2017年 第3期71卷 275-281页
作者: Fan, Chunpeng Wang, Lin Wei, Lynn Sanofi US Inc Dept Biostat & Programming Bridgewater NJ 08807 USA
This article rigorously proves superiority of the proportion chi(2) test to the logistic regression Wald test in terms of power when comparing two rates, despite their asymptotic equivalence under the null hypothesis ... 详细信息
来源: 评论