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检索条件"机构=Biostatistics and Programming department"
47 条 记 录,以下是11-20 订阅
排序:
Modeling and forecasting of wheat of South Asian region countries and role in food security
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Advances in Computational Intelligence 2021年 第6期1卷 1-8页
作者: Yonar, Aynur Yonar, Harun Mishra, Pradeep Kumari, Binita Abotaleb, Mostafa Badr, Amr Department of Statistics Faculty of Science Selçuk University Konya Turkey Department of Biostatistics Faculty of Veterinary Medicine Selçuk University Konya Turkey College of Agriculture J.N.K.V.V. Powarkheda India Department of Agricultural Economics Rashtriya Kisan (PG) College (affiliated to Chaudhary Charan Singh University Meerut) Shamli India Department of System Programming South Ural State University Chelyabinsk Russia Faculty of Science School of Science and Technology University of New England Armidale Australia
Wheat is the most important source of food on earth and vital for food safety. It contains 75–80% carbohydrates, 9–18% protein, fiber, many vitamins (especially B vitamins), calcium, iron, and many macronutrients an...
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A VARIABLE SELECTION APPROACH for HIGHLY CORRELATED PREDICTORS in HIGH-DIMENSIONAL GENOMIC DATA
arXiv
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arXiv 2020年
作者: Wencan, Z.H.U. Lévy-Leduc, Céline Ternès, Nils UMR MIA-Paris AgroParisTech INRAE Université Paris-Saclay Paris75005 France Biostatistics and Programming department Sanofi R&D Chilly Mazarin91380 France
In genomic studies, identifying biomarkers associated with a variable of interest is a major concern in biomedical research. Regularized approaches are classically used to perform variable selection in high-dimensiona... 详细信息
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Bayesian dose-regimen assessment in early phase oncology incorporating pharmacokinetics and pharmacodynamics
arXiv
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arXiv 2020年
作者: Gerard, Emma Zohar, Sarah Thai, Hoai-Thu Lorenzato, Christelle Riviere, Marie-Karelle Ursino, Moreno Centre de Recherche des Cordeliers Sorbonne Université Inserm Université de Paris ParisF-75006 France Oncology biostatistics Biostatistics and Programming department Sanofi R&D Vitry-sur-Seine France Statistical Methodology Group Biostatistics and Programming department Sanofi R&D Chilly-Mazarin France Translation Disease Modeling Digital and Data Science Sanofi R&D Chilly-Mazarin France F-CRIN PARTNERS platform AP-HP Université de Paris Paris France
Phase I dose-finding trials in oncology seek to find the maximum tolerated dose (MTD) of a drug under a specific schedule. Evaluating drug-schedules aims at improving treatment safety while maintaining efficacy. Howev... 详细信息
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Prenatal nitrate exposure from diet and drinking water and timing of puberty in sons and daughters: A nationwide cohort study
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Environment International 2022年 170卷 107659页
作者: Jul Clemmensen, Pernille Brix, Nis Schullehner, Jörg Lunddorf, Lea Lykke Harrits Ernst, Andreas Ebdrup, Ninna Hinchely Bjerregaard, Anne Ahrendt Hansen, Birgitte Thomas Stayner, Leslie Ingi Halldorsson, Thorhallur Frodi Olsen, Sjurdur Sigsgaard, Torben Kolstad, Henrik Albert Ramlau-Hansen, Cecilia Høst Department of Public Health Aarhus University Aarhus Denmark Department of Clinical Genetics Aarhus University Hospital Aarhus Denmark Geological Survey of Denmark and Greenland Aarhus Denmark Aarhus University Aarhus Denmark Fertility Clinic Horsens Regional Hospital Horsens Denmark Department of Epidemiology Research Center for Fetal Programming Statens Serum Institut Copenhagen Denmark Centre for Clinical Research and Prevention Bispebjerg and Frederiksberg Hospital Copenhagen Denmark Division of Epidemiology and Biostatistics University of Illinois at Chicago School of Public Health Chicago United States Faculty of Food Science and Nutrition School of Health Sciences University of Iceland Iceland Section of Epidemiology Institute of Public Health University of Copenhagen Denmark Cirrau -Centre for Integrated Register-based Research at Aarhus University Aarhus Denmark Department of Occupational Medicine Aarhus University Hospital Aarhus Denmark Department of Clinical Medicine Aarhus University Aarhus Denmark
Background: In Western countries, age at pubertal development has declined during the last century in girls, and probably also in boys. No studies have investigated whether nitrate, a widespread environmental exposure... 详细信息
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Implementation of Tripartite Estimands Using Adherence Causal Estimators Under the Causal Inference Framework
arXiv
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arXiv 2020年
作者: Qu, Yongming Luo, Junxiang Ruberg, Stephen J. Department of Biometrics Eli Lilly and Company IndianapolisIN46285 United States Biostatistics and Programming Sanofi 55 Corporate Dr BridgewaterNJ08807 United States Analytix Thinking LCC 11121 Bentgrass Court IndianapolisIN46236 United States
Intercurrent events (ICEs) and missing values are inevitable in clinical trials of any size and duration, making it difficult to assess the treatment effect for all patients in randomized clinical trials. Defining the... 详细信息
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Robust Model Selection and Estimation for Censored Survival Data with High Dimensional Genomic Covariates
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Acta biotheoretica 2019年 第3期67卷 225-251页
作者: Guorong Chen Sijian Wang Guannan Sun Huanxue Pan Department of Finance Beijing Forestry University Beijing China. Department of Statistics and Biostatistics Rutgers University New Brunswick NJ USA. Department of Biostatistics and Programming Sanofi China Beijing China. Department of Finance Beijing Forestry University Beijing China. hxpbjfu@***.
When relating genomic data to survival outcomes, there are three main challenges that are the censored survival outcomes, the high-dimensionality of the genomic data, and the non-normality of data. We propose a method... 详细信息
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A Simulation-free Group Sequential Design with Max-combo Tests in the Presence of Non-proportional Hazards
arXiv
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arXiv 2019年
作者: Wang, Lili Luo, Xiaodong Zheng, Cheng Department of Biotatistics University of Michigan Ann ArborMI United States Department of Biostatistics and Programming Research and Development Sanofi Us BridgewaterNJ United States
Non-proportional hazards (NPH) have been observed in many immuno-oncology clinical trials. Weighted log-rank tests (WLRT) with suitable weights can be used to improve the power of detecting the difference between surv... 详细信息
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7 Phase 3 Trial of an Oral CXCR4 Antagonist, Mavorixafor, for Treatment of Patients With WHIM Syndrome: Preliminary Results From Ongoing Open-Label Extension Period of Continuous Mavorixafor Treatment
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Clinical Immunology 2024年 262卷 109949-109949页
作者: Tarrant, Teresa Badolato, Raffaele Donadieu, Jean Dubuc, Susan Hu, Yanping Jiang, Honghua Li, Sunny Steiner, Deborah Yan, Tina Arbet-Engels, Christophe Associate Professor of Medicine Rheumatology and Immunology/Division of Rheumatology and Immunology Department of Medicine Duke University Durham NC USA Full Professor of Pediatrics Chair of Pediatrics ASST Spedali Civili Brescia/Department of Clinical and Experimental Sciences University of Brescia & ASST Spedali Civili Brescia Italy Pediatric Physician/CHU Paris Est - Hôpital d’Enfants Armand-Trousseau Paris France Senior Director Pharmacovigilance & Risk Management/X4 Pharmaceuticals Boston MA USA Director Clinical Research/X4 Pharmaceuticals Boston MA USA Senior Director Biostatistics/X4 Pharmaceuticals Boston MA USA Senior Director Statistical Programming/X4 Pharmaceuticals Boston MA USA Vice President Clinical Development/X4 Pharmaceuticals Boston MA USA Director Statistical Programming/X4 Pharmaceuticals Boston MA USA Chief Medical Officer/X4 Pharmaceuticals Boston MA USA
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Estimation of group means in generalized linear mixed models
arXiv
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arXiv 2019年
作者: Duan, Jiexin Levine, Michael Luo, Junxiang Qu, Yongming Department of Statistics Purdue University West LafayetteIN47906 United States Biostatistics and programming 55 Corporate Drive Bridgewater SanofiNJ08807 United States Department of Biometrics Eli Lilly Corporate Center Drop Code 2232 IndianapolisIN United States
In this manuscript, we investigate the concept of the mean response for a treatment group mean as well as its estimation and prediction for generalized linear models with a subject-wise random effect. Generalized line... 详细信息
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VP6-2022: Adjuvant pertuzumab and trastuzumab in patients with early HER-2 positive breast cancer in APHINITY: 8.4 years' follow-up
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Annals of Oncology 2022年 第9期33卷 986-987页
作者: S. Loibl J. Jassem A. Sonnenblick D. Parlier E. Winer J. Bergh R.D. Gelber E. Restuccia Y-H. Im C. Huang F. Dalenc I. Calvo M. Procter C. Caballero E. Clark H.L. Gomez Moreno J. Bliss G. Viale J. Bines M. Piccart Medicine and Research Dept. German Breast Group (GBG) Forschungs GmbH Neu-Isenburg Germany Oncology & Radiotherapy Medical University of Gdansk Gdansk Poland Oncology Department Tel Aviv Sourasky Medical Center-(Ichilov) Tel Aviv Israel Clinical Trials Support Unit Institut Jules Bordet Brussels Belgium Yale Cancer Center Yale University School of Medicine - Yale Cancer Center New Haven CT USA Department of Oncology-Pathology Karolinska Institutet and Breast Cancer Centre Cancer Theme Karolinska University Hospital Stockholm Sweden Biostatistics Dana Farber Cancer Institute Boston MA USA Product Development Oncology F. Hoffmann-La Roche Ltd Basel Switzerland Medicine Dept. Hematology/Medical Oncology Division Samsung Medical Center (SMC) - Sungkyunkwan University School of Medicine Seoul Republic of Korea Surgery Dept. NTUH - National Taiwan University Hospital Taipei Taiwan Oncologie 1A Institut Universitaire du Cancer Toulouse - Oncopole Toulouse France Breast Cancer Unit MD Anderson Cancer Center Madrid Madrid Spain Statistics and Programming Frontier Science Scotland Kincraig UK Medical Department Breast International Group (BIG) - AISBL Brussels Belgium Data Sciences - Data & Statistical Sciences (DSS) Roche Products Limited Welwyn Garden City UK Medicine Department INEN - Instituto Nacional de Enfermedades Neoplasicas Lima Peru Clinical Trials and Statistics Unit ICR - Institute of Cancer Research London UK Department of Oncology Università degli Studi di Milano Milan Italy Medical Oncology Department Instituto Nacional de Cancer - Research Center Rio de Janeiro Brazil Institut Jules Bordet Brussels Belgium
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