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检索条件"机构=Biostatistics and Programming department"
47 条 记 录,以下是21-30 订阅
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POS1050 INCIDENCE RATES OF INTERSTITIAL LUNG DISEASE AMONG PATIENTS WITH RHEUMATOID ARTHRITIS TREATED WITH ABATACEPT: A POST HOC POOLED ANALYSIS FROM A COMPENDIUM OF CLINICAL TRIALS
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Annals of the Rheumatic Diseases 2023年 82卷 843-843页
作者: P. Dieudé J. Sparks A. Fischer L. Chen K. Lozenski S. Dahan M. Chaballa W. Little Paris Cité University Bichat Hospital APHP Department of Rheumatology Paris France Brigham and Women's Hospital Harvard Medical School Division of Rheumatology Inflammation and Immunity Boston United States of America Bristol Myers Squibb Lung Fibrosis Lawrenceville United States of America Syneos Health Biostatistics and Statistical Programming Richmond Canada Bristol Myers Squibb Rheumatology Pipeline and Early Assets Lawrenceville United States of America Bristol Myers Squibb Worldwide Medical Lawrenceville United States of America Bristol Myers Squibb US Medical Immunology and Fibrosis Lawrenceville United States of America Bristol Myers Squibb Worldwide Rheumatology Lawrenceville United States of America
Background Interstitial lung disease (ILD) is a recognized complication of RA. Prior studies have suggested stabilization or improvement of ILD in patients with RA (RA-ILD) treated with abatacept. [1,2] Few studies ha...
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9O Phase I/II, open-label, first-in-human study of the anti-GPC3 T cell engager SAR444200 in patients with advanced solid tumors: Updated safety and pharmacokinetic analysis
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ESMO Open 2025年 10卷 104165-104165页
作者: Almhanna, K. Hong, J.Y. Chenard-Poirier, M. Ryoo, B-Y. Lim, D.W-T. El-Khoueiry, A.B. Goh, B-C. Samol, J. Kefsi, A. Perez, R. Meng, R. Masciari, S. Abbadessa, G. Guillemin-Paveau, H. Lepine, L. Zhang, Y. Dumbrava, E.E. Medical Oncology Warren Alpert Medical School of Brown University Providence United States of America Hematology-Oncology Samsung Medical Center (SMC) Seoul Republic of Korea Gastrointestinal Cancer Unit Centre Intégré de Cancérologie - Chu de Québec Québec Canada Department of Oncology Asan Medical Center - University of Ulsan Seoul Republic of Korea Medical Oncology Department NCCS - National Cancer Centre Singapore Medical Oncology Division USC - Kenneth J. Norris Jr. Comprehensive Cancer Center Los Angeles United States of America Hematology-Oncology NCIS - National University Cancer Institute Singapore Singapore Medical Oncology Department National Healthcare Group - Tan Tock Seng Hospital Singapore Oncology Early Development Sanofi Vitry-sur-Seine France Immuno Modulatory Agents-Early Development Sanofi Bridgewater United States of America Research and Development Department Sanofi Cambridge United States of America Early Development in Oncology Sanofi Cambridge United States of America Oncology Early Development Sanofi Cambridge United States of America Pharmacokinetics/Pharmacodynamics VA Sanofi Vitry-sur-Seine France Pharmacokinetics Dynamics and Metabolism Sanofi Vitry-sur-Seine France Department of Biostatistics and Programming Sanofi Cambridge United States of America Investigational Cancer Therapeutics Department The University of Texas MD Anderson Cancer Center - Main Building Houston United States of America
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Imbalanced randomization in clinical trials
arXiv
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arXiv 2018年
作者: Chandereng, Thevaa Wei, Xiaodan Chappell, Rick Department of Statistics University of Wisconsin-Madison WI United States Department of Biostatistics & Medical Informatics University of Wisconsin-Madison WI United States Morgridge Institute of Research WI United States Biostatistics and Programming Sanofi BridgewaterNJ United States
Randomization is a common technique used in clinical trials to eliminate potential bias and confounders in a patient population. Equal allocation to treatment groups is the standard due to its optimal efficiency in ma... 详细信息
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A Family-based graphical approach for testing hierarchically ordered families of hypotheses
arXiv
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arXiv 2018年
作者: Qiu, Zhiying Yu, Li Guo, Wenge Biostatistics and Programming Sanofi BridgewaterNJ08807 United States Department of Mathematical Sciences New Jersey Institute of Technology NewarkNJ07102 United States
In applications of clinical trials, tested hypotheses are often grouped as multiple hierarchically ordered families. To test such structured hypotheses, various gatekeeping strategies have been developed in the litera... 详细信息
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Considerations on trial design and data analysis for multi-regional clinical trials
Considerations on trial design and data analysis for multi-r...
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2017第七届临床评价方法与应用国际研讨会暨生物统计国际研讨会
作者: Hui Quan Biostatistics and Programming Department of Sanofi
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1411P Tusamitamab ravtansine plus ramucirumab as 2L therapy or beyond in patients with metastatic NSq NSCLC and high CEACAM5 expression (CARMEN-LC04)
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Annals of Oncology 2023年 34卷 S807-S807页
作者: G.K. Dy B.C. Cho J. Oliveira M.D. Isla Casado A. Blasco Cordellat M. Zemanova J. Roubec L. Vila Martinez L. Charbonnier C. Soufflet J. de Castro Carpeño Department of Medicine Roswell Park Comprehensive Cancer Center Buffalo NY USA Division of Medical Oncology Yonsei Cancer Center Yonsei University College of Medicine Seoul Republic of Korea Medical Oncology Service Early Phase Clinical Trial Unit-IPO Porto/RISE@CI-IPOP (Health Research Network Experimental Pathology and Therapeutics Group Research Center (CI-IPOP)/RISE@CI-IPOP (Health Research Network) Portuguese Oncology Institute of Porto (IPO Porto)/Porto Comprehensive Cancer Center Porto Portugal Medical Oncology Department Hospital Clínico Universitario Lozano Blesa Zaragoza Spain Medical Oncology Department Hospital General de Valencia Valencia Spain Department of Oncology First Faculty of Medicine Charles University and General University Hospital in Prague Prague Czech Republic Pneumooncology Nemocnice AGEL Ostrava-Vítkovice Ostrava-Vítkovice Czech Republic Oncology Department Consorci Corporació Sanitària Parc Taulí de Sabadell Sabadell Spain Biostatistics & Programming Sanofi Chilly-Mazarin France Clinical Development Sanofi Vitry-sur-Seine France Medical Oncology Service Hospital Universitario La Paz Madrid Spain
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P0054 - An integrated analysis of the efficacy of desvenlafaxine succinate compared with placebo in the treatment of major depressive disorder
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European Psychiatry 2020年 第S2期23卷 S208-S208页
作者: M.E. Thase S.G. Kornstein R. Tummala J.M. Germain Q. Jiang S. Ahmed P.T. Ninan Department of Psychiatry Mood and Anxiety Disorders Treatment and Research Program University of Pennsylvania Philadelphia PA USA Department of Psychiatry and Obstetrics and Gynecology Mood Disorders Institute and The Institute for Womens Health Virginia Commonwealth University School of Medicine Virginia Commonwealth University Richmond VA USA Department of Global Medical Affairs Wyeth Research Collegeville PA USA Department of Neuroscience Wyeth Research Paris France Department of Global Biostatistics and Programming Wyeth Research Collegeville PA USA
Objective:To assess the efficacy of desvenlafaxine succinate (DVS) treatment in patients with major depressive disorder (MDD).Methods:Seven randomized, double-blind, placebo-controlled, short-term studies were pooled ...
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EFFICACY AND SAFETY OF EXPERIMENTAL CHIMERIC ANTIGEN RECEPTOR (CAR) T-CELLS VERSUS AXICABTAGENE CILOLEUCEL (YESCARTA) FOR THE TREATMENT OF RELAPSED/REFRACTORY LARGE B-CELL LYMPHOMA: MATCHING ADJUSTED INDIRECT COMPARISONS AND SYSTEMATIC REVIEW
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Hematology, Transfusion and Cell Therapy 2021年 43卷 S256-S256页
作者: B Weinstein B Muresan S Solano AV Macedo Y Lee Y Su Y Ahn C Camargo G Kim D Carpenter Department of Environmental Health Sciences School of Public Health University at Albany Rensselaer United Kingdom Health Sciences Unit University of Groningen University Medical Center Groningen Groningen The Netherlands Principles and Practice of Clinical Research (PPCR) Program ECPE Harvard T.H. Chan School of Public Health Boston United Kingdom Hematology Clinic Hospital da Polícia Militar Belo Horizonte MG Brazil Department of Pharmaceutical Sciences School of Pharmacy Texas Tech University Health Sciences Center Amarillo United Kingdom Inari Medical Biostatistics and Programming Department Irvine United Kingdom Department of Plastic Surgery Faculdade de Medicina Universidade de São Paulo (FMUSP) São Paulo SP Brazil Institute of Experimental and Clinical Pharmacology and Toxicology Faculty of Medicine University of Freiburg Freiburg Germany Institute for Health and the Environment University at Albany Rensselaer United Kingdom
Introduction Despite the high response rates seen with Chimeric Antigen Receptor (CAR) T-cell therapy for relapsed/refractory Large B-cell lymphoma (R/R LBCL), post-therapy relapse remains a key challenge. To date, no...
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K-groups: A generalization of k-means clustering
arXiv
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arXiv 2017年
作者: Li, Songzi Rizzo, Maria L. Biostatistics and Programming Department Pharmaceutical Product Deparment LLC WilmingtonNC28401 Dept. of Mathematics & Statistics Bowling Green State University Bowling GreenOH43403 United States
We propose a new class of distribution-based clustering algorithms, called k-groups, based on energy distance between samples. The energy distance clustering criterion assigns observations to clusters according to a m... 详细信息
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277MO SAR439859, an oral selective estrogen receptor (ER) degrader (SERD), in ER+/ HER2- metastatic breast cancer (mBC): Biomarker analyses from a phase I/II study
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Annals of Oncology 2020年 31卷 S351-S351页
作者: S. Chandarlapaty A. Bardia S. Lord H. Linden V. Pelekanou N. Ternes J. Ming V. Boutet E. Boitier A. Gosselin J. Sang Lee W. Dos-Santos Bele A. Protopopov M. Celanovic A-L. Bauchet M. Campone Medicine Memorial Sloan Kettering Cancer Center New York NY USA Medical Oncology Massachusetts General Hospital Harvard Medical School Boston MA USA Department of Oncology University of Oxford Churchill Hospital Oxford UK Department of Medicine University of Washington Medical Center Seattle WA USA Clinical Precision Oncology-Tranlsational Medicine Early Development Sanofi Cambridge MA USA Biostatistics and Programming Sanofi Paris France Oncology Sanofi Bridgewater NJ USA TMED & Biomarkers & Clinical Bioanalyses Sanofi Paris France Precision Oncology Sanofi Cambridge MA USA Molecular Profiling Precision Oncology Sanofi Paris France Oncology-OMD Sanofi Cambridge MA USA Medical Oncology Institut de Cancérologie de l'Ouest Saint-Herblain France
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