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作者： Dahne, Sven Bieszmann, Felix Samek, Wojciech Haufe, Stefan Goltz, Dominique Gundlach, Christopher Villringer, Arno Fazli, Siamac Muller, Klaus-Robert Machine Learning Group Department of Computer Science Berlin Institute of Technology Berlin10623 Germany Amazon Berlin10178 Germany Machine Learning Group Department of Video Coding and Analytics Fraunhofer Heinrich Hertz Institute Berlin10587 Germany Laboratory for Intelligent Imaging and Neural Computing Columbia University New YorkNY10027 United States Institute of Psychology University of Leipzig Leipzig04109 Germany Department for Neurology Max Planck Institute for Human Cognitive and Brain Sciences Leipzig04103 Germany Mind-Brain Institute Charite Universitätsmedizin Berlin Humboldt-University Berlin10117 Germany Clinic for Cognitive Neurology University of Leipzig Leipzig04109 Germany Department of Brain and Cognitive Engineering Korea University Seoul136-713 Korea Republic of

Multimodal data are ubiquitous in engineering, communications, robotics, computer vision, or more generally speaking in industry and the sciences. All disciplines have developed their respective sets of analytic tools to fuse the information that is available in all measured modalities. In this paper, we provide a review of classical as well as recent machine learning methods (specifically factor models) for fusing information from functional neuroimaging techniques such as: LFP, EEG, MEG, fNIRS, and fMRI. Early and late fusion scenarios are distinguished, and appropriate factor models for the respective scenarios are presented along with example applications from selected multimodal neuroimaging studies. Further emphasis is given to the interpretability of the resulting model parameters, in particular by highlighting how factor models relate to physical models needed for source localization. The methods we discuss allow for the extraction of information from neural data, which ultimately contributes to 1) better neuroscientific understanding;2) enhance diagnostic performance;and 3) discover neural signals of interest that correlate maximally with a given cognitive paradigm. While we clearly study the multimodal functional neuroimaging challenge, the discussed machine learning techniques have a wide applicability, i.e., in general data fusion, and may thus be informative to the general interested reader. © 2015 IEEE.

关键词： Neurophysiology

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26th Annual Computational Neuroscience Meeting (CNS*2017): Part 1

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BMC Neurosci 2017年第SUPPL 1期18卷 58-58页

作者： Sue Denham Panayiota Poirazi Erik De Schutter Karl Friston Ho Ka Chan Thomas Nowotny Dongqi Han Sungho Hong Sophie Rosay Tanja Wernle Alessandro Treves Sarah Goethals Romain Brette Tomas Van Pottelbergh Rodolphe Sepulchre Alex D. Bird Hermann Cuntz Pedro J. Gonçalves Jan-Matthis Lueckmann Giacomo Bassetto Marcel Nonnenmacher Jakob H. Macke Audrey J. Sederberg Jason N. MacLean Stephanie E. Palmer Ulisse Ferrari Christophe Gardella Olivier Marre Thierry Mora Emina Ibrahimovic Martin Müller Jean-Pascal Pfister Tushar Chauhan Timothée Masquelier Alexandre Montlibert Benoit R. Cottereau Moritz Helias Jannis Schuecker David Dahmen Sven Goedeke Alexandre Hyafil Ainhoa Hermoso-Mendizabal Pavel E. Rueda-Orozco Santiago Jaramillo David Robbe Jaime de la Rocha Marie Rooy Fani Koukouli David DiGregorio Uwe Maskos Boris Gutkin Andrey Yu Verisokin Darya V. Verveyko Dmitry E. Postnov Willy Wong Omid Talakoub Robert Chen Milos Popovic Dmitriy Lisitsyn Eric Drebitz Iris Grothe Sunita Mandon Andreas Kreiter Udo Ernst Peter A. Robinson Xuelong Zhao Kevin M. Aquino John D. Griffiths Grishma Mehta-Pandejee Natasha Gabay James MacLaurin Somwrita Sarkar Tim Kunze Jens Haueisen Thomas R. Knösche Subutai Ahmad Yuwei Cui Marcus Lewis Jeff Hawkins Simona Olmi Spase Petkoski Fabrice Bartolomei Maxime Guye Viktor Jirsa Hazem Toutounji Daniel Durstewitz Matteo Cantarelli Adrian Quintana Boris Marin Matt Earnshaw Padraig Gleeson Robert Court Robert McDougal R. Angus Silver Salvador Dura-Bernal Stephen Larson William W. Lytton Giovanni Idili Lorenzo Posani Simona Cocco Karel Ježek Rémi Monasson School of Psychology Faculty of Health & Human Sciences Plymouth University Plymouth Devon PL4 8AA UK Institute of Molecular Biology and Biotechnology (IMBB) Foundation for Research and Technology-Hellas (FORTH) Heraklion Crete Greece Okinawa Institute of Science and Technology Graduate University Okinawa Japan Wellcome Trust Centre for Neuroimaging Institute of Neurology UCL London WC1N 3BG UK School of Engineering and Informatics University of Sussex Brighton BN1 9QJ UK Graduate School Okinawa Institute of Science and Technology Okinawa 904-0495 Japan Computational Neuroscience Unit Okinawa Institute of Science and Technology Okinawa 904-0495 Japan Cognitive Neuroscience Area Scuola Internazionale Superiore di Studi Avanzati Trieste 34136 Italy Kavli Institute for Systems Neuroscience NTNU Trondheim 7030 Norway Institut de la Vision Sorbonne Universités UPMC Univ Paris 06 INSERM CNRS Paris 75012 France Department of Engineering University of Cambridge Cambridge Cambridgeshire CB2 1PZ UK Ernst Strüngmann Institute for Neuroscience Max Planck Society Frankfurt Germany Frankfurt Institute for Advanced Studies Frankfurt Germany Neural Systems Analysis Research Center Caesar An Associate of the Max Planck Society Bonn Germany Max Planck Institute for Biological Cybernetics Tübingen Germany Bernstein Center for Computational Neuroscience Tübingen Germany Present Address: Biomedical Engineering Department Georgia Institute of Technology Atlanta GA 30306 USA Department of Neurobiology University of Chicago Chicago IL 60637 USA Department of Organismal Biology and Anatomy University of Chicago Chicago IL 60637 USA Committee on Computational Neuroscience University of Chicago Chicago IL 60637 USA Institut de la Vision Sorbonne Universités INSERM Paris France Laboratoire de Physique Statistique Ecole Normale Supérieure Paris France Institute of Molecular Life Sciences University of Zürich 8057 Zürich Switzerland Institute of Neuroinformatics Univer

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Abstracts and Workshops 7th National Spinal Cord Injury Conference November 9-11, 2017 Fallsview Casino Resort Niagara Falls, Ontario, Canada Abstracts

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JOURNAL OF SPINAL CORD MEDICINE 2017年第6期40卷 813-869页

作者： [Anonymous] a NET Team Toronto Rehabilitation Institute - University Health Network Toronto ON Canada. fo Neural Engineering and Therapeutic Team Lyndhurst Centre Toronto Rehabilitation Institute - University Health Network Toronto ON Canada. c Rick Hansen Institute Vancouver BC Canada. ev Rick Hansen Institute Vancouver BC Canada. fc Stan Cassidy Hospital University of New Brunswick Fredericton NB Canada. fd Dalhousie University Halifax NS Canada. e University of Saskatchewan Saskatoon SK Canada. aa University of Calgary Calgary AB Canada. y Dalhousie University Halifax NS Canada. fa Health Sciences Centre Winnipeg MB Canada. fb University of Manitoba Winnipeg MB Canada. h University of Alberta Edmonton AB Canada. i Universite Laval Quebe c City QC Canada. bd Rick Hansen Institute Vancouver BC Canada. fz Clinician Investigator Lyndhurst Centre Toronto Rehabilitation Institute University Health Network and Assistant Professor Department of Medicine Division of Physical Medicine and Rehabilitation University of Toronto. v University of Toront o Toronto ON Canada. n Institute of Biomaterials and Biomedical Engineering University of Toronto Toronto ON Canada. o Toronto Rehabilitation Institute - University Health Network Toronto ON Canada. ga Clinical Scientist Lyndhurst Centre Toronto Rehabilitation Institute University Health Network and Assistant Professor Department of Physical Therapy University of Toronto. dx Department of Electrical and Computer Engineering University of Toronto Toronto ON Canada. fm Lawson Health Research Institute London ON Canada. r Parkwood Institute London ON Canada. bi Parkwood Institute London ON Canada. s University of British Columbia Vancouver BC Canada. t Simon Fraser University Burnaby BC Canada. u DeltaQuest Foundation Concord MA USA. z Institut national d'excellence en santé et en services sociaux (INESSS) Quebec City QC Ca

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An on-line BCI system for hand movement control using real-time recurrent probabilistic neural network

An on-line BCI system for hand movement control using real-t...

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International IEEE/EMBS Conference on neural engineering, CNE

作者： Mohammad Ahmadi Abbas Erfanian Brain-Computer Interface Laboratory Neural Technology Research Center Department of Biomedical Engineering Iran University of Science and Technology Tehran Iran

This paper presents a new EEG-based brain-computer Interface (BCI) for on-line controlling the hand movement in a virtual reality environment. The goal of this research is to develop an interaction technique that will allow the BCI to be effective in real-world scenarios for hand grasp control. For this purpose, two classifiers are designed. The first classifier which is based on the imagination of right-hand movement is for controlling the hand grasping, holding and opening. The second classifier, which is based on the imagination of left-hand movement is designed for error correction and activating the first classifier. One important issue in developing an on-line BCI is the robust and accurate classification of EEG signal which is characterized with a time-varying distribution. In this work, we present a real-time recurrent probabilistic neural network for classifying the EEG signals. The results show that the subjects were able to achieve an accuracy more than 80% during the first session of experiment without off-line training and 73%-91% during the last session using single-trial classification with no adaptation.

关键词： Control systems Real time systems neural networks Recurrent neural networks Biological neural networks Electroencephalography brain computer interfaces Virtual reality Grasping Error correction

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Conveying tactile feedback in sensorized hand neuroprostheses using a biofidelic model of mechanotransduction

Conveying tactile feedback in sensorized hand neuroprosthese...

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作者： Kim, Sung Soo Sripati, Arun P. Vogelstein, R. Jacob Armiger, Robert S. Russell, Alexander F. Bensmaia, Sliman J. Krieger Mind/Brain Institute Johns Hopkins University Baltimore MD 21218 United States Center for the Neural Basis of Cognition Carnegie Melon University Pittsburgh PA 15213 United States Department of Electrical and Computer Engineering Johns Hopkins University Baltimore MD 21218 United States Johns Hopkins Applied Physics Laboratory Laurel MD United States Department of Electrical and Computer Engineering Johns Hopkins University Baltimore MD 20723 United States Department of Organismal Biology and Anatomy University of Chicago Chicago IL 60637 United States

One approach to conveying tactile feedback from sensorized neural prostheses is to characterize the neural signals that would normally be produced in an intact limb and reproduce them through electrical stimulation of the residual peripheral nerves. Toward this end, we have developed a model that accurately replicates the neural activity evoked by any dynamic stimulus in the three types of mechanoreceptive afferents that innervate the glabrous skin of the hand. The model takes as input the position of the stimulus as a function of time, along with its first (velocity), second (acceleration), and third (jerk) derivatives. This input is filtered and passed through an integrate-and-fire mechanism to generate a train of spikes as output. The major conclusion of this study is that the timing of individual spikes evoked in mechanoreceptive fibers innervating the hand can be accurately predicted by this model. We discuss how this model can be integrated in a sensorized prosthesis and show that the activity in a population of simulated afferents conveys information about the location, timing, and magnitude of contact between the hand and an object. © 2009 IEEE.

关键词： Conveying

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Interplay between a phase response curve and spike-timing-dependent plasticity leading to wireless clustering

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Physical Review E 2008年第5期77卷 051909-051909页

作者： Hideyuki Câteau Katsunori Kitano Tomoki Fukai Laboratory for Neural Circut Theory RIKEN Brain Science Institute 2–1 Hirowasa Wako Saitama 351-0198 Japan Department of Human and Computer Intelligence Ritsumeikan University 1-1-1 Nojihigashi Kusatsu Shiga 525-8577 Japan Department of Complexity Science and Engineering University of Tokyo Kashiwa Chiba 277–8561 Japan

A phase response curve (PRC) characterizes the signal transduction between oscillators such as neurons on a fixed network in a minimal manner, while spike-timing-dependent plasiticity (STDP) characterizes the way of rewiring networks in an activity-dependent manner. This paper demonstrates that these two key properties both related to the interaction times of oscillators work synergetically to carve functionally useful circuits. STDP working on neurons that prefer asynchrony converts the initial asynchronous firing to clustered firing with synchrony within a cluster. They get synchronized within a cluster despite their preference to asynchrony because STDP selectively disrupts intracluster connections, which we call wireless clustering. Our PRC analysis reveals a triad mechanism: the network structure affects how the PRC is read out to determine the synchrony tendency, the synchrony tendency affects how the STDP works, and STDP affects the network structure, closing the loop.

关键词： HIPPOCAMPAL-NEURONS SYNAPTIC PLASTICITY COUPLED OSCILLATORS HEBBIAN PLASTICITY RESETTING CURVES CORTICAL-NEURONS SYNCHRONIZATION NETWORKS CORTEX MODEL

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Relationship between synaptic and functional connections of a local cortical network model

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BMC Neurosci 2007年第SUPPL 2期8卷 P69-P69页

作者： Katsunori Kitano Kazuhiro Yamada Tomoki Fukai Department of Human and Computer Intelligence Ritsumeikan University Kusatsu Japan Graduate School of Science and Engineering Ritsumeikan University Kusatsu Japan Laboratory for Neural Circuit Theory RIKEN Brain Science Institute Wako Japan

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Computational Neuroscience: Mathematical and Statistical Perspectives

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Statistics and Its Application 1000年第1期5卷 183-214页

作者： Robert E. Kass Shun-Ichi Amari Kensuke Arai Emery N. Brown Casey O. Diekman Markus Diesmann Brent Doiron Uri T. Eden Adrienne L. Fairhall Grant M. Fiddyment Tomoki Fukai Sonja Grün Matthew T. Harrison Moritz Helias Hiroyuki Nakahara Jun-nosuke Teramae Peter J. Thomas Mark Reimers Jordan Rodu Horacio G. Rotstein Eric Shea-Brown Hideaki Shimazaki Shigeru Shinomoto Byron M. Yu Mark A. Kramer 1Department of Statistics Machine Learning Department and Center for the Neural Basis of Cognition Carnegie Mellon University Pittsburgh Pennsylvania 15213 USA email: kass@stat.cmu.edu 2Mathematical Neuroscience Laboratory RIKEN Brain Science Institute Wako Saitama Prefecture 351-0198 Japan 3Department of Mathematics and Statistics Boston University Boston Massachusetts 02215 USA 5Department of Anesthesia Harvard Medical School Boston Massachusetts 02115 USA 4Department of Brain and Cognitive Sciences Massachusetts Institute of Technology Cambridge Massachusetts 02139 USA 6Department of Mathematical Sciences New Jersey Institute of Technology Newark New Jersey 07102 USA 8Department of Theoretical Systems Neurobiology Institute of Biology RWTH Aachen University 52062 Aachen Germany 7Institute of Neuroscience and Medicine Jülich Research Centre 52428 Jülich Germany 9Department of Mathematics University of Pittsburgh Pittsburgh Pennsylvania 15260 USA 10Department of Physiology and Biophysics University of Washington Seattle Washington 98105 USA 11Division of Applied Mathematics Brown University Providence Rhode Island 02912 USA 12Department of Integrated Theoretical Neuroscience Osaka University Suita Osaka Prefecture 565-0871 Japan 13Department of Mathematics Applied Mathematics and Statistics Case Western Reserve University Cleveland Ohio 44106 USA 14Department of Neuroscience Michigan State University East Lansing Michigan 48824 USA 15Department of Statistics University of Virginia Charlottesville Virginia 22904 USA 17Institute for Brain and Neuroscience Research New Jersey Institute of Technology Newark New Jersey 07102 USA 16Federated Department of Biological Sciences Rutgers University/New Jersey Institute of Technology Newark New Jersey 07102 USA 19Department of Physics Kyoto University Kyoto Kyoto Prefecture 606-8502 Japan 18Honda Research Institute Japan Wako Saitama Prefecture 351-0188 Japan 20Department of Electrical and Compute

Mathematical and statistical models have played important roles in neuroscience, especially by describing the electrical activity of neurons recorded individually, or collectively across large networks. As the field moves forward rapidly, new challenges are emerging. For maximal effectiveness, those working to advance computational neuroscience will need to appreciate and exploit the complementary strengths of mechanistic theory and the statistical paradigm.

关键词： neural data analysis neural modeling neural networks theoretical neuroscience

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