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38th International Cosmic Ray Conference, ICRC 2023

作者： Nam, J. Kuo, C.-Y. Shin, B.K. Chen, P. Chen, Y. Hsu, S.-Y. Huang, J.-J. Huang, M.-H.A. Leung, C.H. Liu, T.-C. Wang, S.-H. Wang, M.-Z. Wang, Y.-H. Besson, D. Novikov, A. Hornhuber, C. Young, R. Department of Physics National Taiwan University Taipei Taiwan Leung Center for Cosmology and Particle Astrophysics National Taiwan University Taipei Taiwan Ulsan National Institute of Science and Technology Ulsan Korea Republic of Department of Energy and Resources National United University Miaoli Taiwan Department of Electrophysics National Yang Ming Chiao Tung University Hsinchu300 Taiwan Department of applied physics National PingTung university PingTung900 Taiwan Chung Cheng Institute of Technology National Defense University TaoYuan335 Taiwan Undergraduate Degree Program of Systems Engineering and Technology National Yang Ming Chiao Tung University Hsinchu300 Taiwan Department of Physics and Astronomy University of Kansas Lawrence United States Instrumentation Design Lab University of Kansas Lawrence United States Moscow Russia Institute of Astronomy and Astrophysics Academia Sinica Astronomy-Mathematics Building No. 1 Sec. 4 Roosevelt Rd. Taipei Taiwan

We report on the development of a drone-borne calibration pulser (cal-pulser) for radio observatories detecting ultra-high energy (UHE) cosmic rays and neutrinos. This system allows us to calibrate the radio detector in its field of view regardless of the accessibility of the site. The system is compact and sufficiently lightweight to be attached to a commercial drone. It consists of a solid-state high-power pulse generator, a programmable attenuator, a transmitting antenna, and a differential GPS (D-GPS) module. The drone, with the ∼1.3 kg payload, has a typical flight time of around 25 minutes, corresponding to a maximum flight distance of around 10 km. After developing the first version of the system in 2019, it successfully demonstrated its calibration performance with the TAROGE stations in Taiwan and the TAROGE-M station in Mt. Melbourne, Antarctica. In 2022, the system was upgraded with a dual-band D-GPS for more reliable operation and more accurate determination of the coordinates of the cal-pulser. In addition to the cal-pulser, we investigated aerial photogrammetry using the built-in camera and the D-GPS, which is an efficient method to determine the coordinates of the detector. For objects within 10 m of the drone, an accuracy of a few millimeter was achieved. These drone-borne cal-pulser and the photogrammetry have become essential calibration procedures in the TAROGE-M experiment. We suggest these approaches may find application in many other radio experiments that detect UHE cosmic rays and neutrinos, such as ARIANNA, BEACON, GRAND, as well as IceCube-Gen2. © Copyright owned by the author(s) under the terms of the Creative Commons.

关键词： Cosmic rays

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Densified mixture design algorithm: A novel mix design concept and its application for green concretes incorporating industrial by-products

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Environmental Progress and Sustainable Energy 2023年第4期42卷

作者： Nguyen, Tan-Hung Limongan, Andrian H. Nguyen, May Huu Hwang, Chao-Lung Huynh, Trong-Phuoc Department of Civil Engineering Can Tho University of Technology Can Tho Viet Nam Department of Civil and Construction Engineering National Taiwan University of Science and Technology Taipei Taiwan Department of Bridge and Tunnel Faculty of Civil Engineering University of Transport Technology Hanoi Viet Nam Civil and Environmental Engineering Program Graduate School of Advanced Science and Engineering Hiroshima University Hiroshima Japan Taiwan Building Technology Center National Taiwan University of Science and Technology Taipei Taiwan Faculty of Civil Engineering College of Engineering Can Tho University Can Tho Viet Nam

Despite the fact that densified mixture design algorithm (DMDA) has been identified as a promising tool for green concrete mix design, its use in real practice has still been minimal worldwide. Due to the lack of precise information on DMDA computation in earlier studies, this work proposes DMDA including fly ash and ground granulated blast-furnace slag as a viable way to improve the long-term performance of green concrete. To encourage the use of DMDA, this study offers a detailed description of the DMDA mix design, as well as a step-by-step standard operating procedure and an empirical example of the computation. Assessments of the long-term performance of green mixtures (self-consolidating concrete and high-performance concrete) and ordinary Portland cement concrete (designed using the conventional method of American Concrete Institute, ACI) were made. Performances of the ACI (O6000 mixture) and DMDA concretes (S6000 and H6000 mixtures) were then compared in terms of compressive strength, elastic modulus, shrinkage, and creep strain. As a result, all of the concrete samples attained the target strength of above 41 MPa (6000 psi) after only 28 days. Moreover, compressive strength, elastic modulus, shrinkage, and creep strain increased significantly in all of the concretes over curing time. Importantly, the experimental results confirmed that both types of DMDA concrete exhibited higher compressive strength and better long-term performance than the ACI concrete under elastic modulus, creep, and shrinkage aspects. © 2023 American Institute of Chemical Engineers.

关键词： Compressive strength

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Label-free and compact approach for bacterial detection in beverages using a dielectrophoresis-integrated 65-GHz inductor-capacitor-oscillator array sensor chip¹

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Food Bioscience 2025年 69卷

作者： Chen, Siyao Yamashige, Yoshihisa Kondo, Naoshi Shiraga, Keiichiro Ogawa, Yuichi of Agriculture Kyoto University Kitashirakawa-oiwake Sakyo Kyoto 606-8502 Japan Distinguished Doctoral Program of Platforms (WISE) Kyoto University Yoshida-honmachi Sakyo Kyoto 606-8501 Japan Research Fellow of the Japan Society for the Promotion of Science Kojimachi Business Center Building 5-3-1 Kojimachi Chiyoda Tokyo 102-0083 Japan Precursory Research for Embryonic Science and Technology (PRESTO) Japan Science and Technology Agency Kawaguchi 332-0012 Japan

Food safety remains a critical concern, with bacterial contamination in beverages posing significant health risks due to rapid bacterial proliferation. Traditional bacterial detection methods, such as plate culture, require days of cultivation, while molecular and optical techniques demand complex pretreatment and specialized equipment, limiting their practicality for routine food inspection. To address these challenges, we developed a rapid, label-free bacterial detection method using a dielectrophoresis (DEP)-integrated 65-GHz inductor-capacitor (LC) oscillator array sensor chip. The sensor chip, fabricated using 65 nm CMOS technology, consists of 1488 sensor elements arranged in a zigzag pattern, each incorporating 5-μm DEP electrodes and a 50-μm LC oscillator. The set up allows for distributed bacterial collection and measurement. We evaluated the sensor's DEP collection patterns for Escherichia coli (E. coli) and Saccharomyces cerevisiae, optimizing conditions for E. coli detection in various beverage matrices, including mineral water, green tea, and bovine milk. The method achieved detection limits of 1.3 × 10⁵ bacterial cells/mL in mineral water and green tea and 5.4 × 10⁶ cells/mL in bovine milk, with an enrichment rate reaching up to 20-fold. The entire detection process was completed within 30 min without the need for pretreatment, external analyzers, or temperature control. Overall, we demonstrated the utility of our simplified and cost-effective bacterial detection technique that enables efficient separation and enrichment of bacteria from food matrices. The sensor's compact design, reusability, and speed make it well-suited for on-site industrial food safety inspections, laying the groundwork for further improvements in real-world applications. © 2025 Elsevier Ltd

关键词： Bacterial detection Beverage inspection Dielectrophoresis Food safety LC oscillator

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Inventories and assessment of POPs in the State of Kuwait as a basis for Stockholm Convention implementation

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Emerging Contaminants 2021年第1期7卷 88-98页

作者： Hassan Alshemmari Environmental Pollution and Climate Program Environment&Life Sciences Research CenterKuwait Institute for Scientific ResearchP.O.Box:24885Safat13109Kuwait Stockholm Convention Regional Center for Capacity-Building and the Transfer of Technology for West Asia(SCRC-Kuwait) Kuwait Institute for Scientific ResearchP.O.Box:24885Safat13109Kuwait

Since 2006,Kuwait has been a party to the Stockholm Convention(SC)on Persistent Organic Pollutants(POPs).According to Article 7 of the SC,each party should develop a National Implementation Plan(NIP)and endeavour to implement the plan for the control and elimination of POPs.A first detailed National Implementation Plan has been developed for Kuwait with the support of the Stockholm Convention Regional Center for Capacity-building and the Transfer of technology for West Asia(SCRC Kuwait)in *** includes a detailed action plan to manage and control the POPs in the country but also with activities to further give regional support for POPs monitoring and *** current paper discusses the major inventory findings for the individual POPs groups including POPs pesticides,polychlorinated biphenyls(PCBs),polybrominated diphenyl ethers,and hexabromocyclododecane(HBCD)as well as Perfluorooctanesulfonic acid(PFOS)and unintentional ***,information from POPs monitoring studies in Kuwait relevant to the NIP is shortly compiled for further informing on the current situation of POPs in *** soil samples were collected and analyzed for selected POPs during the NIP development to generate supplementary information to the POP monitoring studies already conducted in *** relevant areas for the POPs management and control were assessed during the NIP development and are listed in the *** finding in the NIP assessment was that some of the alternatives used are also bioaccumulative with toxicity in biota and that in the NIP ***,alternative pesticides in the current use are an issue of *** one activity in the implementation of the NIP is the avoidance of regrettable alternatives and the use of more sustainable and green chemicals.

关键词： National implementation plan Kuwait Stockholm convention Persistent organic pollutants

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Blockchain technology? Visual Art Marketing Through Non-Fungible Token (NFT) from the Perspectives of Islamic Shariah in Malaysia: A Need Assessment Analyses

Blockchain Technology? Visual Art Marketing Through Non-Fung...

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Computing and Information technology (ICCIT-1441), 2020 International Conference on

作者： Ishak Ramli Mohamad Noorman Masrek Mohd Daud Abdul Rahim Thuraiya Mohd Mohd Ashrof Zaki Yaacob Mohd Radzuan Mohd Rafee Issarezal Ismail Mohamad Rahimi Osman Mohd Khalik Mustafa Muhammad Redza Rosman Program of Fine Art College of Creative Arts Universiti Teknologi MARA Perak Branch Perak Malaysia School of Information Management College of Computing Informatics and Mathematic Universiti Teknologi MARA Shah Alam Selangor Malaysia Program of Fine Art College of Creative Arts Universiti Teknologi MARA Perak Branch Seri Iskandar Campus Perak Malaysia Program of Real Estate Management College of Buit Environment Universiti Teknologi MARA Perak Branch Seri Iskandar Campus Perak Malaysia Division of Zakat Charity and Waqf Academy of Contemporary Islamic Studies Universiti Teknologi MARA Shah Alam Selangor Malaysia Program of Photography College of Creative Arts Universiti Teknologi MARA Perak Branch Seri Iskandar Campus Perak Malaysia Academy of Contemporary Islamic Studies Universiti Teknologi MARA Shah Alam Selangor Malaysia Program of Fashion Design College of Creative Arts Universiti Teknologi MARA Perak Branch Seri Iskandar Campus Perak Malaysia Program of Building Technology College of Built Environment Universiti Teknologi MARA Perak Branch Seri Iskandar Campus Perak Malaysia

ISBN: (数字)9798350353839

ISBN: (纸本)9798350353846

The development of blockchain technology across the globe has seen to be vast, including those related to visual arts. In Islam, anything new: especially those that never existed before, needs to be, obligatory discussed from the Islamic Shariah perspective. Therefore, the vast development of blockchain technology relating to non-fungible token (NFT) towards marketing visual art needs assessment from the Islamic Shariah perspective as there has not been any empirical studies carried out towards it. This paper intends to discuss a need assessment analyses regarding marketing visual art through the NFT platform blockchain technology from the Islamic Shariah perspective in Malaysia. Using the systematic literature review technique, researchers have discussed briefly regarding the development of visual arts, NFT and its trend, and reviewing Islamic perspectives on NFT. As a result, it is necessary for the Islamic Council of Malaysia to explain in detail the marketing of visual arts through NFT. A proper paperwork is crucial to give an overview on the practices regarding NFT that are 1) crypto currency; 2) artwork visual appearance; 3) copyright and consent issue; 4) pricing and value; and 5) royalty and blockchain record - to market of visual arts for Islamic Shariah assessment; in ensuring the muamalat activities amongst Muslims are centred on the faith of Islam.

关键词： Visualization Art Pricing Market research Cryptocurrency Nonfungible tokens Information technology Systematic literature review

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Electrospun Aligned PCL/Gelatin Scaffolds Mimicking the Skin ECM for Effective Antimicrobial Wound Dressings

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Advanced Fiber Materials 2023年第1期5卷 235-251页

作者： Erfan Rezvani Ghomi Rajamani Lakshminarayanan Vijila Chellappan Navin Kumar Verma Amutha Chinnappan Rasoul Esmaeely Neisiany Kottaiswamy Amuthavalli Zhi Sheng Poh Brandon Han Siang Wong Nileshkumar Dubey Roger Narayan Seeram Ramakrishna Department of Mechanical Engineering Center for Nanotechnology and SustainabilityNational University of SingaporeSingapore 117581Singapore Ocular Infections and Antimicrobials Research Group Singapore Eye Research InstituteThe Academia20 College RoadDiscovery TowerSingapore 169856Singapore Institute of Materials Research and Engineering(IMRE) Agency for Science Technology and Research(A*STAR)#08‑032 Fusionopolis WayInnovisSingapore 138634Singapore Lee Kong Chian School of Medicine Nanyang Technological University SingaporeClinical Sciences Building11 Mandalay RoadSingapore 308232Singapore Department of Pharmacy National University of Singapore18 Science Drive 4Singapore 117543Singapore Academic Clinical Program in Ophthalmology and Visual Sciences Academic Clinical Program Duke-NUS Medical SchoolSingapore 169857Singapore National Skin Centre 1 Mandalay RoadSingapore 308205Singapore Department of Materials and Polymer Engineering Faculty of EngineeringHakim Sabzevari UniversitySabzevar ***Iran Faculty of Dentistry National University of SingaporeSingapore 119085Singapore ORCHIDS:Oral Care Health Innovations and Designs Singapore National University of SingaporeSingaporeSingapore 119085Singapore Department of Biomedical Engineering University of North Carolina at Chapel HillChapel HillNC 27514USA

Bacterial infections and multidrug-resistant bacteria are major health burdens in wound *** antimicrobial agents,e.g.,ε-polylysine(ε-PL),provide a broad spectrum of antibacterial properties and support dermal cell ***,ε-PL was incorporated into polycaprolactone(PCL)/gelatin electrospun scaffolds collected at varying rotation ***,the samples were crosslinked using dopamine hydrochloride to provide highly proliferative dressings with broad antimicrobial *** morphological study showed that the electrospun wound dressings were smooth,continuous,and bead-free,with a mean diameter ranging from 267±7 to 331±8 nm for all random and aligned *** fiber alignment of the electrospun PCL/gelatin scaffolds improved their tensile strength and ***,nanofiber mats are highly hydro-philic,which is crucial for an efficient wound *** samples also demonstrated high antimicrobial properties against common wound bacterial strains,including methicillin-resistant Staphylococcus aureus(MRSA),Staphylococcus aureus(SA),Escherichia coli(EC),Acinetobacter baumannii(AB),and Pseudomonas aeruginosa(PA).Mammalian cell prolifera-tion and morphology assays involving primary human dermal fibroblasts(hDFs)and immortalized keratinocytes(HaCaT)showed excellent biocompatibility of the electrospun mats and remarkably aligned ***,aligned mats showed more cell migration than randomly oriented mats,which is desirable for more efficient wound ***,it can be concluded that aligned PCL/gelatin mats containingε-PL are promising for potential use in wound dressings.

关键词： Electrospinning Wound healing Fiber alignment Biomaterials Nanofiber dressing Bacterial infections

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EZH2 inhibitors promote β-like cell regeneration in young and adult type 1 diabetes donors

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Signal Transduction and Targeted Therapy 2024年第2期9卷 679-692页

作者： Keith Al-Hasani Safiya Naina Marikar Harikrishnan Kaipananickal Scott Maxwell Jun Okabe Ishant Khurana Thomas Karagiannis Julia J.Liang Lina Mariana Thomas Loudovaris Thomas Kay Assam El-Osta Epigenetics in Human Health and Disease Program Baker Heart and Diabetes Institute75 Commercial RoadMelbourne 3004 VICAustralia Department of Diabetes Central Clinical SchoolMonash UniversityMelbourne 3004 VICAustralia Epigenetics in Human Health and Disease Laboratory Central Clinical SchoolMonash UniversityMelbourne 3004 VICAustralia School of Science STEM CollegeRMIT UniversityMelbourne 3001 VICAustralia Immunology and Diabetes Unit St Vincent’s Institute of Medical ResearchFitzroy 3065 VICAustralia Department of Medicine and Therapeutics The Chinese University of Hong KongSha TinHong Kong SAR Hong Kong Institute of Diabetes and Obesity Prince of Wales HospitalThe Chinese University of Hong Kong3/F Lui Che Woo Clinical Sciences Building30-32-Ngan Shing StreetSha TinHong Kong SAR Li Ka Shing Institute of Health Sciences The Chinese University of Hong KongSha TinHong Kong SAR Biomedical Laboratory Science Department of TechnologyFaculty of HealthUniversity College CopenhagenCopenhagenDenmark

β-cells are a type of endocrine cell found in pancreatic islets that synthesize,store and release *** type 1 diabetes(T1D),T-cells of the immune system selectively destroy the insulin-producingβ-*** of these cells leads to a lifelong dependence on exogenous insulin administration for ***,there is an urgent need to identify novel therapies that stimulateβ-cell growth and induceβ-cell *** and others have shown that pancreatic ductal progenitor cells are a promising source for regeneratingβ-cells for T1D owing to their inherent differentiation *** transcriptional suppression is refractory to exocrine reaction and tightly controls the regenerative potential by the EZH2 *** the present study,we show that transient stimulation of exocrine cells,derived from juvenile and adult T1D donors to the FDAapproved EZH2 inhibitors GSK126 and Tazemetostat(Taz)influence a phenotypic shift towards aβ-like cell *** transition from repressed to permissive chromatin states are dependent on bivalent H3K27me3 and H3K4me3 chromatin *** EZH2 is fundamental toβ-cell regenerative *** pancreatic ductal cells exhibit insulin production and secretion in response to a physiological glucose challenge ex *** pre-clinical studies underscore the potential of small molecule inhibitors as novel modulators of ductal progenitor differentiation and a promising new approach for the restoration ofβ-like cell function.

关键词： EZH2 struction inhibitors

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A comprehensive analysis of wind power integrated with solar and hydrogen storage systems: Case study of Java's Southern coast

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International Journal of Hydrogen Energy 2024年

作者： Hesty, Nurry Widya Fauziah, Khotimatul Aminuddin Zaky, Toha Fithri, Silvy Rahmah Aman, Mohamad Aziz, Amiral Rostyono, Didik Wijayanto, Rudi Purwo Ifanda Research Center for Energy Conversion and Conservation National Research and Innovation Agency KST BJ Habibie Serpong Tangerang Selatan15343 Indonesia Research Center for Process and Manufacturing Industry Technology National Research and Innovation Agency Building 625 KST BJ Habibie Serpong Banten Tangerang Selatan15314 Indonesia Magister of Industrial Engineering University of Mercu Buana Jakarta11650 Indonesia Study Program of Advanced Climatology Department of Geophysics and Meteorology IPB University Bogor16680 Indonesia Survey and Testing Center for Electricity New Renewable Energy and Energy Conservation Technology Ministry of Energy and Mineral Resources Jakarta12230 Indonesia

Wind and solar energy are vital to the global transition toward sustainable energy systems, driven by the need to reduce fossil fuel dependence, mitigate climate change, and enhance energy security. This study aims to optimize system performance by integrating hydrogen technology and addressing capacity shortages and excess energy. First, a comprehensive analysis of wind characteristics in a strategically important area to meet unaccomplished Indonesia's 2023 wind energy targets, focusing on Java's southern coast using wind speed data from the System Advisor Model (SAM), was conducted. Four scenarios are then evaluated: wind turbine (WT)-battery energy storage system (BESS), WT-photovoltaic (PV)-BESS, WT-fuel cell (FC)-electrolyzer (EL)-hydrogen tank (H2T), and WT-PV–FC–EL-H2T. Key metrics analyzed include excess energy, Levelized Cost of Electricity (LCOE), Net Present Cost (NPC), capacity shortage (CS), and electrolyzer full-load hours (EFH). Results show that average wind speeds reach 4.2 m/s in Pandeglang, with the WT–FC–EL-H2T system being the most reliable, exhibiting a 5% capacity shortage and 68.5% excess electricity. The WT-PV–FC–EL scenario is the most cost-effective, with a COE of $0.508/kWh and an NPC of $2.6 million. These findings provide valuable insights for improving sustainable energy infrastructure in the region. © 2024 Hydrogen Energy Publications LLC

关键词： Clean energy

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Inevitable human exposure of flame retardants on the potential health risk and assessment of PBDEs in soils collected from Sulaibiya, Kuwait

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Arabian Journal of Geosciences 2022年第24期15卷 1-13页

作者： Alshemmari, Hassan Kavil, Yasar N. Sheredah, Abdulaziz Rajagopalan, Smitha Environmental Pollution and Climate Program Environment & Life Sciences Research Center Kuwait Institute for Scientific Research Safat Kuwait Stockholm Convention Regional Center for Capacity-Building and the Transfer of Technology for West Asia (SCRC-Kuwait) Kuwait Institute for Scientific Research Safat Kuwait Department of Marine Chemistry Faculty of Marine Sciences King Abdulaziz University Jeddah Saudi Arabia

Owing to the increase in inflammable polymer materials and related requirements, global demand for polybrominated diphenyl ethers (PBDEs) rose rapidly from the 1970s to the 1990s. BFRs would pollute the soil with dry or wet deposits, as well as landfills. The current research focuses on the levels of PBDEs in the agricultural and non-agricultural soils of Sulaibiya, Kuwait. The study expands the threats of PBDE toxicity to humans as well. The findings will lead to a deeper understanding of PBDE transport practices, environmental effects, and health hazards. The prevalent concentration of BDE-209 congeners can be found in both areas. The average concentrations along the Sulaibiya agricultural and non-agricultural regions were 121.26 ng/g and 50.29 ng/g, respectively, at the current observed sites. The total cancer risk was in the range of 7.67 × 10−9–1316.53 × 10−9 for adults and 10.04 × 10−9–1723.08 × 10−9 for children in the agricultural region. The correspondent total cancer risk in the non-agricultural regions was in the range of 6.14 × 10−9–240.31 × 10−9 for adults and 8.05 × 10−9–314.53 × 10−9 for children. Regardless of the severity of the dismantling activities, the soil organic matter (SOM) of most of the obtained soil samples along agricultural soils varied from 0.2 to 2.1%. As a result, the SOM composition of the samples in this analysis can predominantly be traced to agricultural practices. PCA study was also performed to identify the relationship of soil parameters with the level of PBDEs along with the observed locations.

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Beryllene, the lightest Xene

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npj 2D Materials and Applications 2023年第1期7卷 55页

作者： Chahal, Sumit Bandyopadhyay, Arkamita Yang, Chan-Shan Kumar, Prashant Department of Physics Indian Institute of Technology Patna Bihta CampusPatna-801106 India Universität Bremen Am Fallturm 1 TAB Building Bremen28359 Germany Institute and Undergraduate Program of Electro-Optical Engineering National Taiwan Normal University Taipei11677 Taiwan Micro/Nano Device Inspection and Research Center National Taiwan Normal University Taipei106 Taiwan University of Newcastle NewcastleNSW-2308 Australia

After the discovery of sp2-hybridized graphene and even lighter borophene, the scientific quest for the thinnest metallic sheets prompts the discovery of beryllene. As beryllium lacks p-electrons, the hybridization and structural evolution of beryllene in determining electronic/excitonic behaviors are scientifically interesting. Herein, we report the experimental realization of freestanding flat beryllene sheets with a lateral dimension of ~0.2–4 μm via sonochemical exfoliation. High-resolution transmission electron microscopy establishes the existence of hexagonal, square and stripe crystallographic phases. While characteristic Raman fingerprints ~451 and ~614 cm−1, and experimentally observed electrically metallic nature of beryllene (vindicated by density-functional-theory band structure calculations) establish beryllene synthesis. Room temperature magnetism in Be-G and Be-CNT hybrids (established by Raman mapping and magnetic force microscopic imaging) is an interesting finding. Beryllene was explored as a surface-enhanced Raman spectroscopy (SERS) anchor in molecular sensing, oxidation-resistant, and fire-resistant laminates. It is believed that the discovery of beryllene will lead to novel functionalities and emerging applications. © 2023, Springer Nature Limited.

关键词： High resolution transmission electron microscopy

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