Lithium-ion batteries(LIBs),with the use of sulfides as anode materials,are of research topic because of their high theoretical specific *** is promising for rechargeable energy storage because of their high energy
Lithium-ion batteries(LIBs),with the use of sulfides as anode materials,are of research topic because of their high theoretical specific *** is promising for rechargeable energy storage because of their high energy
Metal sulfides/graphene nanocomposites are of interest because of their potential applications in electrochemical and photoelectrochemical energy conversion and storage. Such materials can be prepared with in situ gro...
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Conventional dissociation‐enhanced lanthanide fluoroimmunoassays (DELFIA) using molecular probes suffer from a low labeling ratio of lanthanide ions (Ln 3+ ) per biomolecule. Herein, we develop a unique bioassay base...
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Conventional dissociation‐enhanced lanthanide fluoroimmunoassays (DELFIA) using molecular probes suffer from a low labeling ratio of lanthanide ions (Ln 3+ ) per biomolecule. Herein, we develop a unique bioassay based on the dissolution‐enhanced luminescence of inorganic lanthanide nanoparticles (NPs). As a result of the highly concentrated Ln 3+ ions in a single Ln 3+ NP, an extremely high Ln 3+ labeling ratio can be achieved, which amplifies significantly the luminescence signal and thus improves the detection sensitivity compared to DELFIA. Utilizing sub‐10 nm NaEuF 4 NPs as dissolution‐enhanced luminescent nanoprobes, we demonstrate the successful in vitro detection of carcinoembryonic antigen (CEA, an important tumor marker) in human serum samples with a record‐low detection limit of 0.1 pg mL −1 (0.5 f M ). This value is an improvement of approximately 3 orders of magnitude relative to that of DELFIA. The dissolution‐enhanced luminescent bioassay shows great promise in versatile bioapplications, such as ultrasensitive and multiplexed in vitro detection of disease markers in clinical diagnosis.
Lanthanide‐doped upconversion nanoparticles (UCNPs) have shown great promise in bioapplications. Exploring new host materials to realize efficient upconversion luminescence (UCL) output is a goal of general concern. ...
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Lanthanide‐doped upconversion nanoparticles (UCNPs) have shown great promise in bioapplications. Exploring new host materials to realize efficient upconversion luminescence (UCL) output is a goal of general concern. Herein, we develop a unique strategy for the synthesis of novel LiLuF 4 :Ln 3+ core/shell UCNPs with typically high absolute upconversion quantum yields of 5.0 % and 7.6 % for Er 3+ and Tm 3+ , respectively. Based on our customized UCL biodetection system, we demonstrate for the first time the application of LiLuF 4 :Ln 3+ core/shell UCNPs as sensitive UCL bioprobes for the detection of an important disease marker β subunit of human chorionic gonadotropin (β‐hCG) with a detection limit of 3.8 ng mL −1 , which is comparable to the β‐hCG level in the serum of normal humans. Furthermore, we use these UCNPs in proof‐of‐concept computed tomography imaging and UCL imaging of cancer cells, thus revealing the great potential of LiLuF 4 :Ln 3+ UCNPs as efficient nano‐bioprobes in disease diagnosis.
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