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IEEE Workshop on Advanced robotics and its Social Impacts, ArSO

作者： Siyuan Gao Chentao Wang Jinying Zhu Jingeng Mai Qining Wang Beijing Innovation Center for Engineering Science and Advanced Technology (BIC-ESAT) Peking University China and also with the Beijing Engineering Research Center of Intelligent Rehabilitation Engineering Beijing China R&D Center of the SpeedSmart Co. Ltd. Beijing China

This paper presents a robotic electrohydraulic transfemoral prosthesis that consists of a controllable bidirectional hydraulic damping and an electrical actuator. The embedded finite-state based controller enables the prosthesis with hydraulic damping adaptation in the stance phase and motorized swing assistance control in the swing phase during level walking. The proposed prosthesis was shorter in length than a fully powered transfemoral prosthesis. Additionally, the prosthesis with swing assistance and bi-directional hydraulic damping control could restore a better gait symmetry on knee angle assessment during level walking, compared with a hydraulic microprocessor controlled transfemoral prosthesis. Preliminary experimental results from a transfemoral amputee demonstrate the potential benefit of the proposed transfemoral prosthesis.

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Oral combined Probiotics Clostridium butyricum and Akkermansia muciniphila Inhibits the Progression of 4T1 Breast Cancer by Activating Bcl-2/Bax Pathway

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Cancer medicine 2025年第11期14卷 e70987页

作者： Xiaowei Li dengxiong Hua daoyan Wu Wei Hong Yingqian Kang Lei Tang Qin Yang Xinxin Wang Boyan Li renmin Li Zhenghong Chen Guzhen Cui Key Laboratory of Microbiology and Parasitology of Education Department of Guizhou & Key Laboratory of Medical Molecular Biology of Guizhou Province Guizhou Medical University Guiyang China. Joint Laboratory of Helicobacter Pylori and Intestinal Microecology of Affiliated Hospital of Guizhou Medical University Guiyang China. Guizhou Key Laboratory of Microbio and Infectious Disease Prevention & Control Guiyang China. Guizhou Provincial Engineering Technology Research Center for Chemical Drug R&D Guizhou Medical University Guiyang China. School of Public Health Guizhou Medical University Guiyang China. Standard Testing Group Co. Ltd. Qingdao China.

BACKGrOUNd:Breast cancer is the most common malignant tumor among women. recent studies have found that gut probiotics and their metabolic products play a significant role in activating the immune system, reshaping the tumor microenvironment, and inhibiting cancer progression. METHOdS:We established a 4T1 tumor-bearing mice model and analyzed the proportions of Cd4 T and Cd8 T cells in the spleen using flow cytometry and immunohistochemistry. The expression levels of TNF-α, IL-6, and IL-10 were measured by enzyme-linked immunosorbent assay. Hematoxylin-eosin staining was used to observe the tumor morphology. Selective protein blotting and quantitative real-time PCr were used to analyze the expression of Bax, Bcl-2, and Caspase-3. Cell proliferation was evaluated using the MTT assay, and apoptosis was detected by flow cytometry. rESULTS:The results indicated that oral administration of CB and AKK possesses the capability to inhibit the progression of 4T1 breast cancer; however, the combined treatment with both strains (CB-AKK) exhibited significantly superior effects compared to each individual strain. Further mechanistic analysis revealed that the CB-AKK combination could activate the antitumor immunity in mice and reshape the tumor microenvironment. Additionally, it was found that the live bacteria and their metabolites derived from CB-AKK could inhibit cell proliferation and promote tumor apoptosis by activating the Bcl-2/Bax signaling pathway. coNCLUSION:This study is the first to demonstrate that orally administered live bacteria CB-AKK can inhibit the progression of 4T1 breast cancer, providing a promising new strategy for the development of innovative biotherapies for breast cancer.

关键词： Akkermansia muciniphila Clostridium butyricum Bcl‐2/Bax signaling pathway apoptosis breast cancer probiotics

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Metalized Porphyrin-Based coFs for conductive Porous Layers in Perovskite Solar Cells to Enhance Electron Injection, defect Passivation, and Lead-Protection

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Angewandte Chemie 2025年

作者： Zhengyan He Tianxiang Luan Qilin Wei Liang Wang dan Huang Haibo Chen Ivan Yu dmitriev Peizhou Li Shufang Zhang William W. Yu School of Chemistry and Chemical Engineering Ministry of Education Key Laboratory of Special Functional Aggregated Materials Shandong Key Laboratory of Advanced Organosilicon Materials and Technologies Shandong University Jinan 250100 China Shandong Provincial Key Laboratory for Science of Material Creation and Energy Conversion Science Center for Material Creation and Energy Conversion Shandong University Qingdao 266237 China School of Integrated Circuits Shandong University Jinan 250101 China State Key Laboratory of Featured Metal Materials and Life-cycle Safety for Composite Structures School of Physical Science and Technology Guangxi University Nanning 530004 China Shandong Muerhls New Material Technology Co. Ltd. Dezhou 251100 China R&D Center of Thin Film Technologies in Energetics Saint Petersburg 194064 Russian Federation School of Physics and Photoelectronic Engineering Ludong University Yantai 264025 China

In perovskite solar cells (PSCs), the introduction of an intermediate layer to bridge the transport and photoactive layers has become a key strategy for enhancing carrier extraction efficiency. However, traditional approaches are often limited by the seesaw effect, making it challenging to achieve an optimal balance between electron transport and defect passivation. In this study, we employed a Cu 2+ -loaded metalized porphyrin-based covalent organic framework (Cu-Por-coF) as a conductive porous layer (CPL) at the perovskite bottom interface. Experimental results showed that a Cu-Por-coF coverage of 19% significantly enhanced electron transport and effectively suppressed long-distance electron diffusion. Moreover, the carefully designed Cu-Por-coF provided abundant active sites, which improved the film-forming quality of the perovskite layer, thereby facilitating the beneficial synergy of electron injection and defect passivation. The n-i-p type devices achieved a power conversion efficiency (PCE) of 25.41% (0.09 cm 2 ) and 21.99% (1.01 cm 2 ). Using Cu-Por-coF to stabilize the perovskite crystal structure, the unencapsulated devices retained over 81% of its initial efficiency after 2000 h. Additionally, Cu-Por-coF effectively chelated lead ions and thus enhanced the environmental sustainability of PSCs.

关键词： covalent organic framework Lead leakage Perovskite solar cell Porous layer

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Promotion of grain growth via solvent fumigation for wide-bandgap perovskite solar cells with low VOC deficit and perovskite/TOPcon tandem solar cells with efficiency >30

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Science bulletin 2025年

作者： Xiang Liao Yuanfang Zhang Zijian Qu Qiang Zeng Mingjun Zhang Jungan Wang Yining Pan Jie Yang damin Zheng Zengsheng Liu Linhong Li Menglei Xu Xinyu Zhang Fangyang Liu School of Metallurgy and Environment Central South University Changsha 410083 China Engineering Research Centre of Advanced Battery Materials Ministry of Education Central South University Changsha 410083 China. Zhejiang Jinko Solar Co. Ltd. Jiaxing 314416 China. Engineering Research Centre of Advanced Battery Materials Ministry of Education Central South University Changsha 410083 China National Energy Metal Resources and New Materials Key Laboratory Central South University Changsha 410083 China. Electronic address: qiang.zeng@***. Zhejiang Jinko Solar Co. Ltd. Jiaxing 314416 China Zhejiang Key Laboratory of Advanced Tandem Photovoltaic Technology Jiaxing 314416 China. National Energy Metal Resources and New Materials Key Laboratory Central South University Changsha 410083 China. Redsolar Central R&D Institute Redsolar New Energy Technology Co. Ltd. Changsha 410205 China. School of Metallurgy and Environment Central South University Changsha 410083 China. Zhejiang Key Laboratory of Advanced Tandem Photovoltaic Technology Jiaxing 314416 China. Electronic address: menglei.xu@***. National Energy Metal Resources and New Materials Key Laboratory Central South University Changsha 410083 China. Electronic address: liufangyang@***.

In perovskite solar cells (PSCs) with a wide bandgap (E ≥ 1.65 eV), mixed halides generate poor-quality perovskite films and lead to a low power conversion efficiency (PCE) due to uncontrolled fast perovskite crystallization. Herein, we propose a strategy to regulate the grain growth of perovskite wet films by fumigating them in a dimethyl sulfoxide (dMSO) atmosphere. due to the better coordination of dMSO with lead halides and organic halides, dMSO fumigation effectively prolongs the existence time of intermediate phases, which slows the crystallization of perovskites, generating perovskite films with large grains and a low defect density. Such high-quality perovskite films were used to fabricate 1.65-eV- and 1.68-eV-bandgap PSCs, which achieved champion PCEs of 23.19% and 22.38%, respectively. The former PSC showed a V deficit of 0.391 V, representing one of the state-of-the-art performances for this bandgap. Monolithic perovskite/tunnelling oxide passivating contact (TOPcon) tandem solar cells (TSCs) were also fabricated using the optimized PSCs as front cells, achieving a champion PCE of 30.9% (certified 30.83%). This study demonstrates an easy-to-operate and effective approach to realize high-performance wide-bandgap PSCs and perovskite/TOPcon TSCs.

关键词： Fumigation Grain growth Tandem solar cells Wide-bandgap perovskites

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Analysis and Impact of Shocking Characteristic in Ultra- fast disconnecting Switch of Hybrid HVdC Breaker

Analysis and Impact of Shocking Characteristic in Ultra- fas...

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IEEE Electronic Power Grid (eGrid)

作者： Xiaolong Zhang Zhixiang Wang Zhuang Li Chong Gao Hongzhou Luan Ning Zhang HVDC Center State Key Laboratory of Advanced Power Transmission Technology Global Energy Interconnection Research Institute Co.Ltd. Beijing China Engineering Center C-EPRI Electric Power Engineering Co.Ltd. Beijing China R&D Center C-EPRI Electric Power Engineering Co.Ltd. Beijing China

ISBN: (数字)9781728157047

ISBN: (纸本)9781728157054

Ultra-fast disconnecting switch is one of the key components in hybrid HVdC circuit breaker. during ultra-fast disconnecting action, a considerable shock to the supporting structure will be produced by the internal moving parts of ultrafast disconnecting switch. In this paper, the movement process of the moving parts within ultra-fast disconnecting switch is described, and the shocking characteristic of ultra-fast disconnecting switch is studied using experimental method. The maximum instantaneous impact force reaches 102kN. In order to reduce the impact of ultra-fast disconnecting switch on supporting structure of HVdC circuit breaker, damping isolators are applied. results of simulation analyses and experiments show that both stress and vibration amplitude have been improved obviously because of the application of damping isolators.

关键词： Switches Force HVdC transmission Isolators damping Circuit breakers Switching circuits

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Effect of rotor length on generating power in horizontal axis wind turbines

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IOP conference Series: Earth and Environmental Science 2020年第1期463卷

作者： Navid Majdi Nasab Jeff Kilby Leila Bakhtiaryfard Dept of Electrical & Electronic Engineering Auckland University of Technology Auckland New Zealand Technology Research Development R&D Center Fusheng Industrial Co. Ltd Taipei Taiwan (R.O.C)

The benefits of the rotor design are optimizing power generation and reducing cost of build in wind turbines. In this study, a performance comparison of horizontal axis wind turbines in terms of their rotor diameter is made using Qblade software. The airfoil selected is the National Advisory committee for Aeronautics (NACA 0012) for all models, and the wind turbines have three blades. From simulations, the optimal rpm for each rotor diameter was calculated, and the generated power for different wind speeds. The results found show that the operation of wind turbines consider need operated with tip speed ratios of between 4 to 7 to give optimal power output. Maximum power was produced for a blade diameter of 170 metres and the highest power coefficient found was for a diameter of 30 metres and for this case also had the highest tip speed ratio of 6.68. Overall results can suggest which diameter range is used for choosing a rotor size that is the most cost-effective.

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HErOHE Challenge: Assessing HEr2 status in breast cancer without immunohistochemistry or in situ hybridization

arXiv

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arXiv 2021年

作者： conde-Sousa, Eduardo Vale, João Feng, Ming Xu, Kele Wang, Yin Mea, Vincenzo della Barbera, david La Montahaei, Ehsan Baghshah, Mahdieh Soleymani Turzynski, Andreas Gildenblat, Jacob Klaiman, Eldad Hong, Yiyu Aresta, Guilherme Araújo, Teresa Aguiar, Paulo Eloy, Catarina Polónia, António I3S - Instituto de Investigação e Inovação em Saúde Universidade Do Porto Portugal INEB - Instituto de Engenharia Biomédica Universidade Do Porto Portugal Department of Pathology Ipatimup Diagnostics Institute of Molecular Pathology and Immunology University of Porto Tongji University Shanghai China National University of Defense Technology Changsha China Department of Mathematics Computer Science and Physics University of Udine Udine Italy Sharif University of Technology Tehran Iran Computer Engineering Department Sharif University of Technology Tehran Iran Private Group Practice for Pathology Lübeck Germany DeePathology Hatidhar 5 Raanana Israel Roche Diagnostics GmbH Nonnenwald 2 Penzberg82377 Germany Department of R&D Center Arontier Co. Ltd Seoul Korea Republic of INESC TEC - Institute for Systems and Computer Engineering Technology and Science Porto Portugal FEUP - Faculty of Engineering University of Porto Porto Portugal FMUP - Faculty of Medicine University of Porto Porto Portugal INEB/i3S Rua Alfredo Allen 208 Porto4200-135 Portugal

Breast cancer is the most common malignancy in women, being responsible for more than half a million deaths every year. As such, early and accurate diagnosis is of paramount importance. Human expertise is required to diagnose and correctly classify breast cancer and define appropriate therapy, which depends on the evaluation of the expression of different biomarkers such as the transmembrane protein receptor HEr2. This evaluation requires several steps, including special techniques such as immunohistochemistry or in situ hybridization to assess HEr2 status. With the goal of reducing the number of steps and human bias in diagnosis, the HErOHE Challenge was organized, as a parallel event of the 16th European congress on digital Pathology, aiming to automate the assessment of the HEr2 status based only on hematoxylin and eosin stained tissue sample of invasive breast cancer. Methods to assess HEr2 status were presented by 21 teams worldwide and the results achieved by some of the proposed methods open potential perspectives to advance the state-of-the-art. © 2021, CC BY.

关键词： diseases

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Optimized Wake-up Scheme with Bounded delay for Energy-Efficient MTC

Optimized Wake-up Scheme with Bounded Delay for Energy-Effic...

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IEEE Global communications conference

作者： Soheil rostami Sandra Lagen Mario costa Paolo dini Mikko Valkama Huawei Technologies Oy (Finland) Co. Ltd Helsinki R&D Center Centre Tecnològic de Telecomunicacions de Catalunya (CTTC/CERCA) Barcelona Spain Huawei Technologies Oy (Finland) Co. Ltd Department of Electronics and Communications Engineering Tampere University of Technology Finland

ISBN: (数字)9781728109626

ISBN: (纸本)9781728109633

The limitations of state-of-the-art cellular modems prevent achieving low-power and low-latency Machine Type communications (MTC) based on current power saving mechanisms alone. recently, the concept of wake-up scheme has been proposed to enhance battery lifetime of 5G devices, while reducing the buffering delay. The existing wake-up algorithms use static operational parameters that are determined by the radio access network at the start of the user's session. In this paper, the average power consumption of the wake-up enabled MTC UE is modeled by using a semi-Markov process and then optimized through a delay-constrained optimization problem, by which the optimal wake-up cycle is obtained in closed form. Numerical results show that the proposed solution reduces the power consumption of an optimized discontinuous reception (drX) scheme by up to 40% for a given delay requirement.

关键词： delays Power demand Energy consumption Mathematical model Modems 5G mobile communication Numerical models

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corrigendum to "physicochemical properties, structural analysis, and activity of Shancigu polysaccharides" [Int. J. Biol. Macromol. 298 (2025) 140071]

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International journal of biological macromolecules 2025年 312卷 144334页

作者： Yun Liu Jie Xu Chiyu Ge Tiantian Zhang Hongyi Chu Yi Jing Zhimeng Xu Guoyong Xie Jun Yuan Jiangsu Key Laboratory of Regional Specific Resource Pharmaceutical Transformation Huaiyin Institute of Technology Huai'an 223003 China National & Local Joint Engineering Research Center for Mineral Salt Deep Utilization Huaiyin Institute of Technology Huai'an 223003 China. Department of Resources Science of Traditional Chinese Medicines School of Traditional Chinese Pharmacy China Pharmaceutical University Nanjing 210009 China School of Pharmacy Jiangsu Food and Pharmaceutical Science College Huai'an 223005 China. Department of Food Nutrition and Safety/National R&D Center for Chinese Herbal Medicine Processing School of Engineering China Pharmaceutical University Nanjing 211198 China. Department of Chinese herbal medicinal resources Tianjiang Pharmaceutical Co. Ltd. Jiangyin 214400 China. Department of Resources Science of Traditional Chinese Medicines School of Traditional Chinese Pharmacy China Pharmaceutical University Nanjing 210009 China. Electronic address: guoyongxie321@***. National & Local Joint Engineering Research Center for Mineral Salt Deep Utilization Huaiyin Institute of Technology Huai'an 223003 China. Electronic address: yuanj_hyit@***.

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Sliding Mode control Method of Photoelectric Turntable Based on LuGre Friction Model

Sliding Mode Control Method of Photoelectric Turntable Based...

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International conference on Electrical Machines and Systems (ICEMS)

作者： Ninghao Cui Qian Zhang Qunjing Wang Zhenglei Ma Jianjun Chen deyin Lin Institute of Electrical Engineering and Automation Chemistry Anhui University Hefei China National Engineering Laboratory of Energy-Saving Motor & Control Technology Anhui University Hefei China Collaborative Innovation Center of Industrial Energy-Saving and Power Quality Control Anhui University Hefei China R&D Department Shanghai Yingjue Technology Co. Ltd. Shanghai China Nanjing EXSCIN Information Technology CO. Ltd. Nanjing China Shanghai Yingjue Technology Co. Ltd. Shanghai China

ISBN: (纸本)9781728133997

Nonlinear friction is one of the main factors affecting the performance of the photoelectric turntable. In this paper, a sliding mode controller based on LuGre friction model is proposed in the servo system of photoelectric turntable. Firstly, the friction model is established and the parameters of the model are identified by genetic algorithm. Secondly, the model-based nonlinear disturbance observer is constructed to estimate the friction and other disturbances. Finally, a sliding mode controller is designed to ensure the tracking error and accuracy of the system. The simulation results show that this method is able to reduce the tracking error and improve the tracking performance of the system.

关键词： Friction Sliding mode control Servomotors disturbance observers Mathematical model Torque

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