O1 Regulation of genes by telomere length over long distances Jerry W. Shay O2 The microtubule destabilizer KIF2A regulates the postnatal establishment of neuronal circuits in addition to prenatal cell survival, cell ...
O1 Regulation of genes by telomere length over long distances Jerry W. Shay O2 The microtubule destabilizer KIF2A regulates the postnatal establishment of neuronal circuits in addition to prenatal cell survival, cell migration, and axon elongation, and its loss leading to malformation of cortical development and severe epilepsy Noriko Homma, Ruyun Zhou, Muhammad Imran Naseer, Adeel G. Chaudhary, Mohammed Al-Qahtani, Nobutaka Hirokawa O3 Integration of metagenomics and metabolomics in gut microbiome research Maryam Goudarzi, Albert J. Fornace Jr. O4 A unique integrated system to discern pathogenesis of central nervous system tumors Saleh Baeesa, Deema Hussain, Mohammed Bangash, Fahad Alghamdi, Hans-Juergen Schulten, Angel Carracedo, Ishaq Khan, Hanadi Qashqari, Nawal Madkhali, Mohamad Saka, Kulvinder S. Saini, Awatif Jamal, Jaudah Al-Maghrabi, Adel Abuzenadah, Adeel Chaudhary, Mohammed Al Qahtani, Ghazi Damanhouri O5 RPL27A is a target of miR-595 and deficiency contributes to ribosomal dysgenesis Heba Alkhatabi O6 Next generation DNA sequencing panels for haemostatic and platelet disorders and for Fanconi anaemia in routine diagnostic service Anne Goodeve, Laura Crookes, Nikolas Niksic, Nicholas Beauchamp O7 Targeted sequencing panels and their utilization in personalized medicine Adel M. Abuzenadah O8 International biobanking in the era of precision medicine Jim Vaught O9 Biobank and biodata for clinical and forensic applications Bruce Budowle, Mourad Assidi, Abdelbaset Buhmeida O10 Tissue microarray technique: a powerful adjunct tool for molecular profiling of solid tumors Jaudah Al-Maghrabi O11 The CEGMR biobanking unit: achievements, challenges and future plans Abdelbaset Buhmeida, Mourad Assidi, Leena Merdad O12 Phylomedicine of tumors Sudhir Kumar, Sayaka Miura, Karen Gomez O13 Clinical implementation of pharmacogenomics for colorectal cancer treatment Angel Carracedo, Mahmood Rasool O14 From association to causality: translation of GWAS findings for genomic me
PatternLab for proteomics is a self-contained computational environment for analyzing shotgun proteomic data. Recent improvements incorporate modules to facilitate the computational analysis, such as FastaDBXtractor f...
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The low-frequency 1/f noise in graphene transistors has been studied extensively owing to the proposed graphene applications in analog devices and communication systems [1-5]. The studies were motivated by the fact th...
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The AAAI-11 workshop program was held Sunday and Monday, August 7-18, 2011, at the Hyatt Regency San Francisco in San Francisco, California USA. The AAAI-11 workshop program included 15 workshops covering a wide range...
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This work presents a combination of the Model-View-Controller pattern with the Evolutionary Acquisition Interdisciplinary Research Project Management for web services *** intends to promote an increase in productivity...
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This work presents a combination of the Model-View-Controller pattern with the Evolutionary Acquisition Interdisciplinary Research Project Management for web services *** intends to promote an increase in productivity and to facilitate interdisciplinary web services *** consists of an independent database for users' feedback that together with technological opportunities and evolving threats considerations may start a new release of the system allowing a dynamic evolution through acquiring new features or correcting errors,but the new release decision is not *** other words,web service evolution is accomplished adding requirements analysis into the Model-View-Controller pattern,which is incorporated into Interdisciplinary Research Project Management.
Neurons in the medial entorhinal cortex of rats have been found to respond in a two-dimensional hexagonal "grid" pattern anchored to the environment. "Grid cells" with different spatial frequencies...
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ISBN:
(纸本)9781467302180
Neurons in the medial entorhinal cortex of rats have been found to respond in a two-dimensional hexagonal "grid" pattern anchored to the environment. "Grid cells" with different spatial frequencies are thought to contribute to the creation of unimodal "place" cell responses useful for spatial navigation. In this paper we present results from an analog VLSI circuit that generates a hexagonal grid of activity using continuous attractor dynamics and transmits this pattern via neuron-like spikes. This circuit is a component of a larger system for modeling the neural circuits underlying mammalian spatial navigation.
In order to approach human hand performance levels, artificial anthropomorphic hands/fingers have increasingly incorporated human biomechanical features. However, the performance of finger reaching movements to visual...
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ISBN:
(纸本)9781424441198
In order to approach human hand performance levels, artificial anthropomorphic hands/fingers have increasingly incorporated human biomechanical features. However, the performance of finger reaching movements to visual targets involving the complex kinematics of multijointed, anthropomorphic actuators is a difficult problem. This is because the relationship between sensory and motor coordinates is highly nonlinear, and also often includes mechanical coupling of the two last joints. Recently, we developed a cortical model that learns the inverse kinematics of a simulated anthropomorphic finger. Here, we expand this previous work by assessing if this cortical model is able to learn the inverse kinematics for an actual anthropomorphic humanoid finger having its two last joints coupled and controlled by pneumatic muscles. The findings revealed that single 3D reaching movements, as well as more complex patterns of motion of the humanoid finger, were accurately and robustly performed by this cortical model while producing kinematics comparable to those of humans. This work contributes to the development of a bioinspired controller providing adaptive, robust and flexible control of dexterous robotic and prosthetic hands.
In this work, we propose a new algorithm to solve a variant of the Vehicle Routing Problem that is the Single Vehicle Routing Problem with Deliveries and Selective Pickups (SVRPDSP). Our algorithm produces good qualit...
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In this work, we propose a new algorithm to solve a variant of the Vehicle Routing Problem that is the Single Vehicle Routing Problem with Deliveries and Selective Pickups (SVRPDSP). Our algorithm produces good quality solutions that are better than the best known solutions in the literature. In order to reduce the time spent to solve large-sized instances, we also propose here a parallel implementation of our algorithm that explores a heterogeneous environment composed of a CPU and a GPU. Therefore, our algorithm harnesses the tremendous computing power of the GPU to improve the performance of the local searches computation. We obtained average speedups from 2.73 to 16.23 times with our parallel approach.
The combination of testing techniques is considered an effective strategy to evaluate a software product. However, the selection of which techniques to combine in a software project has been an interesting challenge i...
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The low-frequency 1/f noise in graphene transistors has been studied extensively owing to the proposed graphene applications in analog devices and communication systems [1-5]. The studies were motivated by the fact th...
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The low-frequency 1/f noise in graphene transistors has been studied extensively owing to the proposed graphene applications in analog devices and communication systems [1-5]. The studies were motivated by the fact that the low-frequency noise can be up-converted by device nonlinearity and contribute to the phase noise of the system. Similarly, the sensor sensitivity is often limited by the electronic low-frequency noise. Therefore, noise is usually considered as one of the main limiting factors for the device or overall system operation. However, the electronic noise spectrum itself can be used as a sensing parameter increasing the sensor sensitivity and selectivity. Here, we show that vapors of different chemicals produce distinguishably different effects on the low-frequency noise spectra of the graphene-on-Si transistor. Our study showed that some gases change the electrical resistance of pristine graphene devices without changing their low-frequency noise spectra while other gases modify the noise spectra by inducing Lorentzian components with distinctive features. The characteristic corner frequency f C of the Lorentzian noise bulges in graphene devices is different for different chemicals and varies from f C =10 - 20 Hz for tetrahydrofuran to f C =1300 - 1600 Hz for chloroform. We tested the selected set of chemicals vapors on different graphene device samples and alternated different vapors for the same samples. The obtained results indicate that 1/f noise in combination with other sensing parameters can allow one to achieve the selective gas sensing with a single pristine graphene transistor. Our method of gas sensing with graphene does not require graphene surface functionalization or fabrication of an array of the devices with each tuned to a certain chemical. The observation of the Lorentzian components in the vapor-exposed graphene can also help in developing an accurate theoretical description of the noise mechanism in graphene.
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