检索结果-内蒙古大学图书馆

GWAS meta-analysis of over 29,000 people with epilepsy identifies 26 risk loci and subtype-specific genetic architecture

引用

Nature genetics 2023年第9期55卷 1471-1482页

作者： Remi Stevelink Dorothee Kasteleijn-Nolst Trenite Bobby P. C. Koeleman Dick Lindhout Anja C. M. Sonsma Ciarán Campbell Gianpiero L. Cavalleri Norman Delanty Hany El-Naggar Austin Lacey Peter Widdess-Walsh Colin P. Doherty Siwei Chen Claire Churchhouse Mark J. Daly Yen-Chen A. Feng Daniel P. Howrigan Mitja I. Kurki Benjamin M. Neale Aarno Palotie Wei Zhou Namrata Gupta Henrike O. Heyne Bassel Abou-Khalil Kevin F. Haas R. S. Taneja Oluyomi M. Adesoji Michael Nothnagel Peter Nürnberg Thomas Sander Zaid Afawi Ilan Blatt Amos D. Korczyn Elisabetta Amadori Ganna Balagura Antonella Riva Marcello Scala Paolo Scudieri Pasquale Striano Federico Zara Michele Iacomino Francesca Madia Alison Anderson Patrick Kwan Terence J. O’Brien Slavé Petrovski K. Meng Tan Marian Todaro Joseph Anderson Danielle M. Andrade Quratulain Zulfiqar Ali Grazia Annesi Pauls Auce Andreja Avbersek Simona Balestrini Vera Braatz Claudia B. Catarino Krishna Chinthapalli Jennifer Jamnadas-Khoda Dalia Kasperavičiūte Costin Leu Josemir W. Sander Sanjay M. Sisodiya Sara Zagaglia Melanie Bahlo Karen L. Oliver Mark D. Baker Beata Fonferko-Shadrach William O. Pickrell Carmen Barba Claudia Bianchini Viola Doccini Renzo Guerrini Davide Mei Martino Montomoli Elena Parrini Annalisa Vetro Karen Barboza Fabrice Bartolomei Thomas Bast Bernhard J. Steinhoff Larry Baum Stacey S. Cherny Pak Sham Tobias Baumgartner Christian E. Elger Kerstin Hallmann Wolfram S. Kunz Rainer Surges Randi von Wrede Gábor Zsurka Betül Baykan Nerses Bebek Yeşim Kesim Albert J. Becker Susanne Schoch Felicitas Becker Caitlin A. Bennett Samuel F. Berkovic Stephanie L. Leech Brigid M. Regan Ingrid E. Scheffer Bianca Berghuis Ahmad Beydoun Wassim Nasreddine Francesca Bisulli Lidia Di Vito Lorenzo Ferri Tania Giangregorio Laura Licchetta Raffaella Minardi Barbara Mostacci Carlotta Stipa Paolo Tinuper Lorenzo Muccioli Federica Pondrelli Dheeraj R. Bobbili Emadeldin Hassanin Roland Krause Zied Landoulsi Patrick May Ingo Borggraefe Christian Bosselmann Christian Hengsbach Josua Kegele Stephen Lauxmann Department of Genetics University Medical Center Utrecht Utrecht The Netherlands Stichting Epilepsie Instellingen Nederland (SEIN) Heemstede The Netherlands School of Pharmacy and Biomolecular Sciences The Royal College of Surgeons in Ireland Dublin Ireland The FutureNeuro Research Centre Dublin Ireland Department of Neurology Beaumont Hospital Dublin Ireland Department of Neurology St. James’s Hospital Dublin Ireland Analytic and Translational Genetics Unit Department of Medicine Massachusetts General Hospital and Harvard Medical School Boston MA USA Program in Medical and Population Genetics Broad Institute of MIT and Harvard Cambridge MA USA Stanley Center for Psychiatric Research Broad Institute of Harvard and M.I.T Cambridge MA USA Institute for Molecular Medicine Finland (FIMM) University of Helsinki Helsinki Finland Psychiatric & Neurodevelopmental Genetics Unit Department of Psychiatry Massachusetts General Hospital and Harvard Medical School Boston MA USA Division of Biostatistics Institute of Epidemiology and Preventive Medicine College of Public Health National Taiwan University Taipei Taiwan Hasso Plattner Institute Digital Health Center University of Potsdam Potsdam Germany Hasso Plattner Institute Mount Sinai School of Medicine New York City NY USA Department of Neurology Vanderbilt University Medical Center Nashville TN USA Cologne Center for Genomics (CCG) University of Cologne Faculty of Medicine and University Hospital Cologne Cologne Germany University Hospital Cologne Cologne Germany Department of Neurology Charité Universitaetsmedizin Berlin Campus Virchow-Clinic Berlin Germany Tel-Aviv University Sackler Faculty of Medicine Ramat Aviv Israel Department of Neurology Sheba Medical Center Ramat Gan Israel Department of Neurosciences Rehabilitation Ophthalmology Genetics Maternal and Child Health University of Genova Genova Italy IRCCS Istituto Giannina Gaslini Genova Italy Department of Medicine University of Melbour

Epilepsy is a highly heritable disorder affecting over 50 million people worldwide, of which about one-third are resistant to current treatments. Here we report a multi-ancestry genome-wide association study including...

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Decoding the genome of bloodsucking midge Forcipomyia taiwana (Diptera: Ceratopogonidae): Insights into odorant receptor expansion

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Insect biochemistry and molecular biology 2024年 168卷 104115页

作者： Ming-Der Lin Chia-Hsien Chuang Chih-Hsin Kao Shu-Hwa Chen Szu-Chieh Wang Ping-Heng Hsieh Guan-Yu Chen Chun-Chia Mao Jeng-Yi Li Mei-Yeh Jade Lu Chung-Yen Lin Department of Molecular Biology and Human Genetics Tzu Chi University 701 Zhongyang Rd. Sec. 3 Hualien 97004 Taiwan Institute of Medical Sciences Tzu Chi University 701 Zhongyang Rd. Sec. 3 Hualien 97004 Taiwan. Electronic address: mingder@gms.tcu.edu.tw. Department of Otolaryngology-Head and Neck Surgery Lausanne University Hospital and University of Lausanne Rue du Bugnon 46 1011 Lausanne Switzerland Agora Cancer Research Centre Rue du Bugnon 25A 1011 Lausanne Switzerland. Electronic address: Chia-Hsien.Chuang@chuv.ch. Institute of Information Science Academia Sinica 128 Academia Road Sec. 2 Nankang Taipei 11529 Taiwan Institute of Fisheries Science National Taiwan University No. 1 Sec. 4 Roosevelt Rd. Taipei 10617 Taiwan. Electronic address: kaochihhsin@***. TMU Research Center of Cancer Translational Medicine Taipei Medical University 250 Wu-Xing Street Taipei 11031 Taiwan. Electronic address: sophia0715@tmu.edu.tw. Institute of Information Science Academia Sinica 128 Academia Road Sec. 2 Nankang Taipei 11529 Taiwan. Electronic address: paper90312@yahoo.com.tw. Institute of Information Science Academia Sinica 128 Academia Road Sec. 2 Nankang Taipei 11529 Taiwan. Electronic address: phhsieh@iis.sinica.edu.tw. Department of Molecular Biology and Human Genetics Tzu Chi University 701 Zhongyang Rd. Sec. 3 Hualien 97004 Taiwan. Electronic address: 104711131@gms.tcu.edu.tw. Institute of Fisheries Science National Taiwan University No. 1 Sec. 4 Roosevelt Rd. Taipei 10617 Taiwan. Electronic address: r10b45014@ntu.edu.tw. Biodiversity Research Center Academia Sinica 128 Academia Road Sec. 2 Nankang Taipei 11529 Taiwan. Electronic address: orionisky@***. Biodiversity Research Center Academia Sinica 128 Academia Road Sec. 2 Nankang Taipei 11529 Taiwan. Electronic address: meiyehlu@gate.sinica.edu.tw. Institute of Fisheries Science National Taiwan University No. 1 Sec. 4 Roosevelt Rd. Taipei 10617 Taiwan Genome and Systems Biology Deg

Biting midges, notably those within the Ceratopogonidae family, have long been recognized for their epidemiological significance, both as nuisances and vectors for disease transmission in vertebrates. Despite their im... 详细信息

Biting midges, notably those within the Ceratopogonidae family, have long been recognized for their epidemiological significance, both as nuisances and vectors for disease transmission in vertebrates. Despite their impact, genomic insights into these insects, particularly beyond the Culicoides genus, remain limited. In this study, we assembled the Forcipomyia taiwana (Shiraki) genome, comprising 113 scaffolds covering 130.4 Mbps-with the longest scaffold reaching 7.6 Mbps and an N50 value of 2.6 Mbps-marking a pivotal advancement in understanding the genetic architecture of ceratopogonid biting midges. Phylogenomic analyses reveal a shared ancestry between F. taiwana and Culicoides sonorensis Wirth & Jones, dating back approximately 124 million years, and highlight a dynamic history of gene family expansions and contractions within the Ceratopogonidae family. Notably, a substantial expansion of the odorant receptor (OR) gene family was observed, which is crucial for the chemosensory capabilities that govern biting midges' interactions with their environment, including host seeking and oviposition behaviors. The distribution of OR genes across the F. taiwana genome displays notable clusters on scaffolds, indicating localized tandem gene duplication events. Additionally, several collinear regions were identified, hinting at segmental duplications, inversions, and translocations, contributing to the olfactory system's evolutionary complexity. Among the 156 ORs identified in F. taiwana, 134 are biting midge-specific ORs, distributed across three distinct clades, each exhibiting unique motif features that distinguish them from the others. Through weighted gene co-expression network analysis, we correlated distinct gene modules with sex and reproductive status, laying the groundwork for future investigations into the interplay between gene expression and adaptive behaviors in F. taiwana. In conclusion, our study not only highlights the unique olfactory repertoire of cerat

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Author Correction: Highly recurrent CBS epimutations in gastric cancer CpG island methylator phenotypes and inflammation

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Genome biology 2021年第1期22卷 181页

作者： Nisha Padmanabhan Huang Kie Kyon Arnoud Boot Kevin Lim Supriya Srivastava Shuwen Chen Zhiyuan Wu Hyung-Ok Lee Vineeth T Mukundan Charlene Chan Yarn Kit Chan Ong Xuewen Jason J Pitt Zul Fazreen Adam Isa Manjie Xing Ming Hui Lee Angie Lay Keng Tan Shamaine Ho Wei Ting Micah A Luftig Dennis Kappei Warren D Kruger Jinsong Bian Ying Swan Ho Ming Teh Steve George Rozen Patrick Tan Programme in Cancer and Stem Cell Biology Duke-NUS Medical School 8 College road Singapore 169857 Singapore. Centre for Computational Biology Duke-NUS Medical School Singapore 169857 Singapore. Department of Medicine Yong Loo Lin School of Medicine National University of Singapore Singapore 119228 Singapore. Bioprocessing Technology Institute A*STAR 20 Biopolis Way #06-01 Centros Singapore 138668 Singapore. Department of Pharmacology Yong Loo Lin School of Medicine National University of Singapore Singapore 117600 Singapore. Cancer Biology Program Fox Chase Cancer Center Philadelphia PA USA. Cancer Science Institute of Singapore National University of Singapore Singapore 117599 Singapore. Department of Molecular Genetics and Microbiology Duke Centre for Virology Duke University School of Medicine Durham NC USA. Department of Biochemistry Yong Loo Lin School of Medicine National University of Singapore Singapore 117596 Singapore. National University of Singapore (Suzhou) Research Institute Suzhou 215123 China. Department of Pathology National University of Singapore Singapore 119228 Singapore. Programme in Cancer and Stem Cell Biology Duke-NUS Medical School 8 College road Singapore 169857 Singapore. gmstanp@dukenus.edu.sg. Cancer Science Institute of Singapore National University of Singapore Singapore 117599 Singapore. gmstanp@dukenus.edu.sg. Genome Institute of Singapore Singapore 138672 Singapore. gmstanp@dukenus.edu.sg. SingHealth/Duke-NUS Institute of Precision Medicine National Heart Centre Singapore Singapore 169856 Singapore. gmstanp@dukenus.edu.sg. Singapore Gastric Cancer Consortium Singapore 119074 Singapore. gmstanp@dukenus.edu.sg. Department of Physiology National University of Singapore Singapore 117593 Singapore. gmstanp@dukenus.edu.sg.

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The importance of transparency and reproducibility in artificial intelligence research

arXiv

引用

arXiv 2020年

作者： Haibe-Kains, Benjamin Adam, George Alexandru Hosny, Ahmed Khodakarami, Farnoosh Waldron, Levi Wang, Bo McIntosh, Chris Kundaje, Anshul Greene, Casey S. Hoffman, Michael M. Leek, Jeffrey T. Huber, Wolfgang Brazma, Alvis Pineau, Joelle Tibshirani, Robert Hastie, Trevor Ioannidis, John P.A. Quackenbush, John Aerts, Hugo J.W.L. Princess Margaret Cancer Centre University Health Network TorontoON Canada Department of Medical Biophysics University of Toronto TorontoON Canada Department of Computer Science University of Toronto TorontoON Canada Ontario Institute for Cancer Research TorontoON Canada Vector Institute for Artificial Intelligence TorontoON Canada Program Brigham and Women's Hospital Harvard Medical School BostonMA United States Radiation Oncology and Radiology Dana-Farber Cancer Institute Brigham and Women's Department of Epidemiology and Biostatistics Institute for Implementation Science in Population Health CUNY Graduate School of Public Health and Health Policy New YorkNY United States Peter Munk Cardiac Centre University Health Network TorontoON Canada Hospital Harvard Medical School BostonMA United States Department of Genetics Stanford University School of Medicine StanfordCA United States Dept. of Systems Pharmacology and Translational Therapeutics Perelman School of Medicine University of Pennsylvania PhiladelphiaPA United States Childhood Cancer Data Lab Alex's Lemonade Stand Foundation PhiladelphiaPA United States Department of Biostatistics Johns Hopkins Bloomberg School of Public Health BaltimoreMD United States European Molecular Biology Laboratory Genome Biology Unit Heidelberg Germany European Molecular Biology Laboratory European Bioinformatics Institute EMBL-EBI Hinxton United Kingdom McGill University MontrealQC Canada Montreal Institute for Learning Algorithms QC Canada StanfordCA United States Department of Biomedical Data Science Stanford University School of Medicine StanfordCA United States Departments of Medicine of Health Research and Policy and of Biomedical Data Science Stanford University School of Medicine StanfordCA United States Department of Statistics Stanford University School of Humanities and Sciences StanfordCA United States Department of Biostatistics Harvard T.H Chan School of Public Health BostonMA Un

In their study, McKinney et al. showed the high potential of artificial intelligence for breast cancer screening. However, the lack of detailed methods and computer code undermines its scientific value. We identify ob... 详细信息

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When one size does not fit all: Reconsidering PCOS etiology, diagnosis, clinical subgroups, and subgroup-specific treatments

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Endocrine and Metabolic Science 2024年 14卷

作者： Unfer, V. Kandaraki, E. Pkhaladze, L. Roseff, S. Vazquez-Levin, M.H. Laganà, A.S. Shiao-Yng, C. Yap-Garcia, M.I.M. Greene, N.D.E. Soulage, C.O. Bevilacqua, A. Benvenga, S. Barbaro, D. Pintaudi, B. Wdowiak, A. Aragona, C. Kamenov, Z. Appetecchia, M. Porcaro, G. Hernandez Marin, I. Facchinetti, F. Chiu, T. Pustotina, O. Papalou, O. Nordio, M. Cantelmi, T. Cavalli, P. Vucenik, I. Unfer, V.R. Dinicola, S. Salehpour, S. Stringaro, A. Montaninno Oliva, M. Tugushev, M. Prapas, N. Bizzarri, M. Espinola, M.S.B. Di Lorenzo, C. Ozay, A.C. Nestler, J. The Experts Group on Inositol in Basic and Clinical Research (EGOI) Rome 00161 Italy UniCamillus-Saint Camillus International University of Health Sciences Rome 00156 Italy Department of Endocrinology and Diabetes HYGEIA Hospital Athens Marousi Greece Ioseb Zhordania Institute of Reproductology Tbilisi Georgia Reproductive Endocrinology and Infertility South Florida Institute for Reproductive Medicine (IVFMD) FL United States National Council of Scientific and Technical Research Instituto de Biología y Medicina Experimental (IBYME Buenos Aires Argentina Unit of Gynecologic Oncology ARNAS “Civico – Di Cristina – Benfratelli” Department of Health Promotion Mother and Child Care Internal Medicine and Medical Specialties (PROMISE) University of Palermo Palermo 90127 Italy Department of Obstetrics and Gynecology Yong Loo Lin School of Medicine National University of Singapore and the Singapore Institute for Clinical Sciences A*STAR Singapore St. Luke's Medical Center College of Medicine William H. Quasha Memorial Philippines Newlife Birth Defects Research Centre and Developmental Biology and Cancer Program Institute of Child Health University College London London United Kingdom University of Lyon INSERM U1060 CarMeN INSA de Lyon Université Claude Bernard Lyon 1 Villeurbanne France Department of Dynamic and Clinical Psychology Sapienza University Rome Italy Department of Clinical and Experimental Medicine University of Messina Italy Director of U.O. Endocrinology in Livorno Hospital USL Nordovest Toscana Italy ASST Grande Ospedale Metropolitano Niguarda Milan Italy Diagnostic Techniques Unit Medical University of Lublin Poland Systems Biology Laboratory Department of Experimental Medicine Sapienza University Rome Italy Department of Internal Medicine Medical University of Sofia Sofia Bulgaria Oncological Endocrinology Unit Regina Elena National Cancer Institute IRCCS Rome Italy Women's Health Center USL Umbria Terni Italy Human Reproduction Department

Polycystic Ovary Syndrome (PCOS) is a complex endocrine disorder that affects a large proportion of women. Due to its heterogeneity, the best diagnostic strategy has been a matter of contention. Since 1990 scientific ... 详细信息

Polycystic Ovary Syndrome (PCOS) is a complex endocrine disorder that affects a large proportion of women. Due to its heterogeneity, the best diagnostic strategy has been a matter of contention. Since 1990 scientific societies in the field of human reproduction have tried to define the pivotal criteria for the diagnosis of PCOS. The consensus Rotterdam diagnostic criteria included the presence of hyperandrogenism, oligo/anovulation, and polycystic ovarian morphology (PCOM), and have now been updated to evidence based diagnostic criteria in the 2018 and 2023 International Guideline diagnostic criteria endorsed by 39 societies internationally. Within the Rotterdam Criteria, at least two out of three of the above-mentioned features are required to be present to diagnose PCOS, resulting in four phenotypes being identified: phenotype A, characterized by the presence of all the features, phenotype B, exhibiting hyperandrogenism and oligo-anovulation, phenotype C, presenting as hyperandrogenism and PCOM and finally the phenotype D that is characterized by oligo-anovulation and PCOM, lacking the hyperandrogenic component. However, it is the hypothesis of the EGOI group that the Rotterdam phenotypes A, B, and C have a different underlying causality to phenotype D. Recent studies have highlighted the strong correlation between insulin resistance and hyperandrogenism, and the pivotal role of these factors in driving ovarian alterations, such as oligo-anovulation and follicular functional cyst formation. This new understanding of PCOS pathogenesis has led the authors to hypothesis that phenotypes A, B, and C are endocrine-metabolic syndromes with a metabolic clinical onset. Conversely, the absence of hyperandrogenism and metabolic disturbances in phenotype D suggests a different origin of this condition, and point towards novel pathophysiological mechanisms;however, these are still not fully understood. Further questions have been raised regarding the suitability of the “phenot

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Author Correction: LILRB3 genetic variation is associated with kidney transplant failure in African American recipients

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Nature medicine 2025年 2025 Apr 15页

作者： Zeguo Sun Zhengzi Yi Chengguo Wei Wenlin Wang Tianyuan Ren Paolo Cravedi Fasika Tedla Stephen C Ward Evren Azeloglu Daniel R Schrider Yun Li Atlas Khan Francesca Zanoni Jia Fu Sumaria Ali Shun Liu Deguang Liang Tong Liu Hong Li Caixia Xi Thi Ha Vy Gohar Mosoyan Quan Sun Ashwani Kumar Zhongyang Zhang Samira Farouk Kirk Campell Jordi Ochando Kyung Lee Steve Coca Jenny Xiang Patricia Connolly Lorenzo Gallon Philip J O'Connell Robert Colvin Madhav C Menon Girish Nadkarni John C He Monica Kraft Xuejun Jiang Xuewu Zhang Krzysztof Kiryluk Aravind Cherukuri Fadi G Lakkis Weiguo Zhang Shu-Hsia Chen Peter S Heeger Weijia Zhang Renal Division Department of Medicine Icahn School of Medicine at Mount Sinai New York NY USA. Suzhou Institute of Systems Medicine Chinese Academy of Medical Sciences Suzhou China. The Recanati/Miller Transplantation Institute Icahn School of Medicine at Mount Sinai New York NY USA. Department of Pathology and Laboratory Medicine Icahn School of Medicine at Mount Sinai New York NY USA. Department of Genetics University of North Carolina at Chapel Hill Chapel Hill NC USA. Division of Nephrology Department of Medicine Columbia University New York NY USA. Center for Immunotherapy Research Houston Methodist Neal Cancer Center and Houston Methodist Research Institute Houston TX USA. Department of Pharmacology University of Texas Southwestern Medical Center Dallas TX USA. Cell Biology Program Memorial Sloan Kettering Cancer Center New York NY USA. Center for Advanced Proteomics Research and Department of Microbiology Biochemistry and Molecular Genetics Rutgers University Newark NJ USA. Department of Medicine Yale University New Haven CT USA. Department of Genetics and Genomics Icahn School of Medicine at Mount Sinai New York NY USA. Department of Oncological Sciences Icahn School of Medicine at Mount Sinai New York NY USA. Department of Microbiology and Immunology Weil Cornell Medicine New York NY USA. VericiDx Inc. Franklin TN USA. Department of Medicine University of Illinois Chicago Chicago IL USA. Centre for Transplant and Renal Research Westmead Institute for Medical Research University of Sydney Sydney New South Wales Australia. Department of Pathology Massachusetts General Hospital and Harvard Medical School Boston MA USA. Department of Medicine Icahn School of Medicine at Mount Sinai New York NY USA. Departments of Surgery Immunology and Medicine University of Pittsburgh School of Medicine Pittsburgh PA USA. Department of Medicine Cedars-Sinai Medical Center Los Angeles CA USA. Renal Division Department of Medicine Icahn S

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Publisher Correction: Statistically and functionally fine-mapped blood eQTLs and pQTLs from 1,405 humans reveal distinct regulation patterns and disease relevance

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Nature genetics 2024年第10期56卷 2281页

作者： Qingbo S Wang Takanori Hasegawa Ho Namkoong Ryunosuke Saiki Ryuya Edahiro Kyuto Sonehara Hiromu Tanaka Shuhei Azekawa Shotaro Chubachi Yugo Takahashi Saori Sakaue Shinichi Namba Kenichi Yamamoto Yuichi Shiraishi Kenichi Chiba Hiroko Tanaka Hideki Makishima Yasuhito Nannya Zicong Zhang Rika Tsujikawa Ryuji Koike Tomomi Takano Makoto Ishii Akinori Kimura Fumitaka Inoue Takanori Kanai Koichi Fukunaga Seishi Ogawa Seiya Imoto Satoru Miyano Yukinori Okada Department of Genome Informatics Graduate School of Medicine University of Tokyo Tokyo Japan. qingbow@m.u-tokyo.ac.jp. Department of Statistical Genetics Osaka University Graduate School of Medicine Suita Japan. qingbow@m.u-tokyo.ac.jp. M&D Data Science Center Tokyo Medical and Dental University Tokyo Japan. Department of Infectious Diseases Keio University School of Medicine Tokyo Japan. hounamugun@keio.jp. Department of Pathology and Tumor Biology Kyoto University Kyoto Japan. Department of Statistical Genetics Osaka University Graduate School of Medicine Suita Japan. Department of Respiratory Medicine and Clinical Immunology Osaka University Graduate School of Medicine Suita Japan. Department of Genome Informatics Graduate School of Medicine University of Tokyo Tokyo Japan. Division of Pulmonary Medicine Department of Medicine Keio University School of Medicine Tokyo Japan. Faculty of Medicine Osaka University Suita Japan. Center for Data Sciences Brigham and Women's Hospital Harvard Medical School Boston MA USA. Divisions of Genetics and Rheumatology Department of Medicine Brigham and Women's Hospital Harvard Medical School Boston MA USA. Program in Medical and Population Genetics Broad Institute of MIT and Harvard Cambridge MA USA. Laboratory of Children's Health and Genetics Division of Health Science Osaka University Graduate School of Medicine Suita Japan. Department of Pediatrics Osaka University Graduate School of Medicine Suita Japan. Division of Genome Analysis Platform Development National Cancer Center Research Institute Tokyo Japan. Institute for the Advanced Study of Human Biology (WPI-ASHBi) Kyoto University Kyoto Japan. Health Science Research and Development Center (HeRD) Tokyo Medical and Dental University Tokyo Japan. Laboratory of Veterinary Infectious Disease Department of Veterinary Medicine Kitasato University Tokyo Japan. Department of Respiratory Medicine Nagoya University Graduate School of Medicine Nagoya Japan. In

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Complement system genetic variability shapes pancreatic cancer risk

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Pancreatology 2023年 23卷 e28-e29页

作者： Langtry, Alberto Rabadan, Raul Alonso, Lola Lawlor, Rita Carrato, Alfredo Hidalgo, María Iglesias, Mar Molero, Xavier Löhr, Matthias MICHALSKI, Christoph Perea, José O'Rorke, Michael Barberá, Victor Manuel Tardón, Adonina Farré, Antoni Muñoz-Bellvis, Luis Crnogorac-Jurcevic, Tatjana Domínguez-Muñoz, Enrique Gress, Thomas Greenhalf, William Sharp, Linda Filip, Ioan Sabroso, Sergio Balsells, Joaquim Costello, Eithne Ilzarbe, Lucas Kleeff, Jórg Kong, B. Mora, Josefina O'Driscoll, Damian Scarpa, Aldo Ye, Weimin Yu, J. Real, Francisco X. Malats, Núria López de Maturana, Evangelina Genetic and Molecular Epidemiology Group Spanish National Cancer Research Centre (CNIO) Madrid Spain Program for Mathematical Genomics Department of Systems Biology Department of Biomedical Informatics Columbia University New York USA ARC-Net Centre for Applied Research on Cancer and Department of Pathology and Diagnostics University and Hospital trust of Verona Verona Italy Department of Oncology Ramón y Cajal University Hospital IRYCIS Alcala University Madrid Spain Madrid-Norte-Sanchinarro Hospital Madrid Spain Hospital del Mar—Parc de Salut Mar Universitat Pompeu Fabra Barcelona Spain Hospital Universitari Vall d’Hebron Vall d’Hebron Research Institute (VHIR) Barcelona Spain Gastrocentrum Karolinska Institutet and University Hospital Stockholm Sweden Department of Surgery Technical University of Munich Munich Germany Department of Surgery Hospital 12 de Octubre and Department of Surgery and Health Research Institute Fundación Jiménez Díaz Madrid Spain College of Public Health The University of Iowa Iowa USA Molecular Genetics Laboratory General University Hospital of Elche Elche Spain Department of Medicine Instituto Universitario de Oncología del Principado de Asturias (IUOPA) Instituto de Investigación Sanitaria del Principado de Asturias (ISPA) Oviedo Spain Department of Gastroenterology and Clinical Biochemistry Hospital de la Santa Creu i Sant Pau Barcelona Spain Department of Surgery Hospital Universitario de Salamanca – IBSAL. Universidad de Salamanca Salamanca Spain Barts Cancer Institute Centre for Molecular Oncology Queen Mary University of London London United Kingdom Department of Gastroenterology University Clinical Hospital of Santiago de Compostela Santiago Spain Department of Gastroenterology University Hospital of Giessen and Marburg Marburg Germany Department of Molecular and Clinical Cancer Medicine University of Liverpool Liverpool United Kingdom

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Author Correction: π-HuB: the proteomic navigator of the human body

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Nature 2025年第8046期637卷 E22页

作者： Fuchu He Ruedi Aebersold Mark S Baker Xiuwu Bian Xiaochen Bo Daniel W Chan Cheng Chang Luonan Chen Xiangmei Chen Yu-Ju Chen Heping Cheng Ben C Collins Fernando Corrales Jürgen Cox Weinan E Jennifer E Van Eyk Jia Fan Pouya Faridi Daniel Figeys George Fu Gao Wen Gao Zu-Hua Gao Keisuke Goda Wilson Wen Bin Goh Dongfeng Gu Changjiang Guo Tiannan Guo Yuezhong He Albert J R Heck Henning Hermjakob Tony Hunter Narayanan Gopalakrishna Iyer Ying Jiang Connie R Jimenez Lokesh Joshi Neil L Kelleher Ming Li Yang Li Qingsong Lin Cui Hua Liu Fan Liu Guang-Hui Liu Yansheng Liu Zhihua Liu Teck Yew Low Ben Lu Matthias Mann Anming Meng Robert L Moritz Edouard Nice Guang Ning Gilbert S Omenn Christopher M Overall Giuseppe Palmisano Yaojin Peng Charles Pineau Terence Chuen Wai Poon Anthony W Purcell Jie Qiao Roger R Reddel Phillip J Robinson Paola Roncada Chris Sander Jiahao Sha Erwei Song Sanjeeva Srivastava Aihua Sun Siu Kwan Sze Chao Tang Liujun Tang Ruijun Tian Juan Antonio Vizcaíno Chanjuan Wang Chen Wang Xiaowen Wang Xinxing Wang Yan Wang Tobias Weiss Mathias Wilhelm Robert Winkler Bernd Wollscheid Limsoon Wong Linhai Xie Wei Xie Tao Xu Tianhao Xu Liying Yan Jing Yang Xiao Yang John Yates Tao Yun Qiwei Zhai Bing Zhang Hui Zhang Lihua Zhang Lingqiang Zhang Pingwen Zhang Yukui Zhang Yu Zi Zheng Qing Zhong Yunping Zhu State Key Laboratory of Medical Proteomics Beijing Proteome Research Center National Center for Protein Sciences (Beijing) Beijing Institute of Lifeomics Beijing China. hefc@***. International Academy of Phronesis Medicine (Guangdong) Guangdong China. hefc@***. Department of Biology Institute of Molecular Systems Biology ETH Zurich Zurich Switzerland. aebersold@imsb.biol.ethz.ch. Macquarie Medical School Macquarie University Sydney New South Wales Australia. Institute of Pathology and Southwest Cancer Center Southwest Hospital Third Military Medical University (Army Medical University) and Key Laboratory of Tumor Immunopathology Ministry of Education of China Chongqing China. Institute of Health Service and Transfusion Medicine Beijing China. Department of Pathology and The Sidney Kimmel Comprehensive Cancer Center Johns Hopkins University Baltimore MD USA. State Key Laboratory of Medical Proteomics Beijing Proteome Research Center National Center for Protein Sciences (Beijing) Beijing Institute of Lifeomics Beijing China. Key Laboratory of Systems Biology Center for Excellence in Molecular Cell Science Shanghai Institute of Biochemistry and Cell Biology Chinese Academy of Sciences Shanghai China. Department of Nephrology First Medical Center of Chinese PLA General Hospital Nephrology Institute of the Chinese People's Liberation Army State Key Laboratory of Kidney Diseases National Clinical Research Center for Kidney Diseases Beijing Key Laboratory of Kidney Disease Research Beijing China. Institute of Chemistry Academia Sinica Taipei China. National Biomedical Imaging Center State Key Laboratory of Membrane Biology Institute of Molecular Medicine Peking-Tsinghua Center for Life Sciences College of Future Technology Peking University Beijing China. School of Biological Sciences Queen's University of Belfast Belfast UK. Functional Proteomics Laboratory Centro Nacional de Biotecnología-CSIC Madrid Spain. Computational Systems Biochemistry Research Group Ma

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Author Correction: Multi-ancestry polygenic mechanisms of type 2 diabetes

引用

Nature medicine 2024年第7期30卷 2091页

作者： Kirk Smith Aaron J Deutsch Carolyn McGrail Hyunkyung Kim Sarah Hsu Alicia Huerta-Chagoya Ravi Mandla Philip H Schroeder Kenneth E Westerman Lukasz Szczerbinski Timothy D Majarian Varinderpal Kaur Alice Williamson Noah Zaitlen Melina Claussnitzer Jose C Florez Alisa K Manning Josep M Mercader Kyle J Gaulton Miriam S Udler Diabetes Unit Endocrine Division Department of Medicine Massachusetts General Hospital Boston MA USA. Center for Genomic Medicine Massachusetts General Hospital Boston MA USA. Programs in Metabolism and Medical & Population Genetics Broad Institute of MIT and Harvard Cambridge MA USA. Department of Medicine Harvard Medical School Boston MA USA. Biomedical Sciences Graduate Program University of California San Diego La Jolla CA USA. Committee on Genetics Genomics and Systems Biology University of Chicago Chicago IL USA. Section of Genetic Medicine Department of Medicine University of Chicago Chicago IL USA. Clinical and Translational Epidemiology Unit Massachusetts General Hospital Boston MA USA. Department of Endocrinology Diabetology and Internal Medicine Medical University of Bialystok Bialystok Poland. Clinical Research Centre Medical University of Bialystok Bialystok Poland. Vertex Pharmaceuticals Boston MA USA. Precision Healthcare University Research Institute Queen Mary University of London London UK. MRC Epidemiology Unit Institute of Metabolic Science University of Cambridge Cambridge UK. Department of Neurology University of California Los Angeles Los Angeles CA USA. Department of Computational Medicine University of California Los Angeles Los Angeles CA USA. Department of Human Genetics University of California Los Angeles Los Angeles CA USA. Novo Nordisk Foundation Center for Genomic Mechanisms of Disease Broad Institute of MIT and Harvard Cambridge MA USA. Department of Pediatrics University of California San Diego San Diego CA USA. Diabetes Unit Endocrine Division Department of Medicine Massachusetts General Hospital Boston MA USA. mudler@mgh.harvard.edu. Center for Genomic Medicine Massachusetts General Hospital Boston MA USA. mudler@mgh.harvard.edu. Programs in Metabolism and Medical & Population Genetics Broad Institute of MIT and Harvard Cambridge MA USA. mudler@mgh.harvard.edu. Department of Medicine Ha

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