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检索条件"机构=Cancer Data Science Program"
255 条 记 录,以下是131-140 订阅
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Author Correction: Genomic footprints of activated telomere maintenance mechanisms in cancer (Dec, 10.1038/s41467-019-13824-9, 2022)
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NATURE COMMUNICATIONS 2022年 第1期13卷 1-1页
作者: Sieverling, Lina Hong, Chen Koser, Sandra D. Ginsbach, Philip Kleinheinz, Kortine Hutter, Barbara Braun, Delia M. Cortes-Ciriano, Isidro Xi, Ruibin Kabbe, Rolf Park, Peter J. Eils, Roland Schlesner, Matthias Brors, Benedikt Rippe, Karsten Jones, David T. W. Feuerbach, Lars Division of Applied Bioinformatics German Cancer Research Center (DKFZ) 69120 Heidelberg Germany Faculty of Biosciences Heidelberg University 69120 Heidelberg Germany Division of Applied Bioinformatics German Cancer Research Center (DKFZ) Heidelberg Germany Faculty of Biosciences Heidelberg University Heidelberg Germany Division of Theoretical Bioinformatics German Cancer Research Center (DKFZ) 69120 Heidelberg Germany Department for Bioinformatics and Functional Genomics Institute for Pharmacy and Molecular Biotechnology (IPMB) and BioQuant 69120 Heidelberg Germany Division of Theoretical Bioinformatics German Cancer Research Center (DKFZ) Heidelberg Germany Institute of Pharmacy and Molecular Biotechnology and BioQuant Heidelberg University Heidelberg Germany German Cancer Consortium (DKTK) Heidelberg Germany National Center for Tumor Diseases (NCT) Heidelberg Heidelberg Germany Heidelberg Center for Personalized Oncology (DKFZ-HIPO) German Cancer Research Center (DKFZ) Heidelberg Germany German Cancer Consortium (DKTK) German Cancer Research Center (DKFZ) Heidelberg Germany Division of Chromatin Networks German Cancer Research Center (DKFZ) and BioQuant 69120 Heidelberg Germany Department of Biomedical Informatics Harvard Medical School Boston Massachusetts 02115 USA Department of Chemistry Centre for Molecular Science Informatics University of Cambridge Cambridge CB2 1EW UK Ludwig Center at Harvard Medical School Boston Massachusetts 02115 USA Department of Biomedical Informatics Harvard Medical School Boston MA USA Department of Chemistry Centre for Molecular Science Informatics University of Cambridge Cambridge UK Ludwig Center at Harvard Medical School Boston MA USA School of Mathematical Sciences and Center for Statistical Science Peking University Beijing 100871 China Heidelberg University Heidelberg Germany New BIH Digital Health Center Berlin Institute of Health (BIH) and Charité - Universitätsmedizin Berlin Berlin Germany Bioi
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The Multi-modality Cell Segmentation Challenge: Towards Universal Solutions
arXiv
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arXiv 2023年
作者: Ma, Jun Xie, Ronald Ayyadhury, Shamini Ge, Cheng Gupta, Anubha Gupta, Ritu Gu, Song Zhang, Yao Lee, Gihun Kim, Joonkee Lou, Wei Li, Haofeng Upschulte, Eric Dickscheid, Timo de Almeida, José Guilherme Wang, Yixin Han, Lin Yang, Xin Labagnara, Marco Gligorovski, Vojislav Scheder, Maxime Rahi, Sahand Jamal Kempster, Carly Pollitt, Alice Espinosa, Leon Mignot, Tâm Middeke, Jan Moritz Eckardt, Jan-Niklas Li, Wangkai Li, Zhaoyang Cai, Xiaochen Bai, Bizhe Greenwald, Noah F. Van Valen, David Weisbart, Erin Cimini, Beth A. Cheung, Trevor Brück, Oscar Bader, Gary D. Wang, Bo Peter Munk Cardiac Centre University Health Network TorontoON Canada Department of Laboratory Medicine and Pathobiology University of Toronto TorontoON Canada Vector Institute TorontoON Canada Department of Molecular Genetics University of Toronto TorontoON Canada Donnelly Centre University of Toronto TorontoON Canada Princess Margaret Cancer Centre University Health Network TorontoON Canada School of Medicine and Pharmacy Ocean University of China Qingdao China New Delhi India Laboratory Oncology Dr. BRA-IRCH All India Institute of Medical Sciences New Delhi India Department of Image Reconstruction Nanjing Anke Medical Technology Co. Ltd. Nanjing China Shanghai Artificial Intelligence Laboratory Shanghai China Graduate School of AI KAIST Seoul Korea Republic of Shenzhen Research Institute of Big Data Shenzhen China Shenzhen China Helmholtz AI Research Center Jülich Jülich Germany Faculty of Mathematics and Natural Sciences Institute of Computer Science Heinrich Heine University Düsseldorf Düsseldorf Germany Hinxton United Kingdom Champalimaud Foundation - Centre for the Unknown Lisbon Portugal Department of Bioengineering Stanford University Palo AltoCA United States Tandon School of Engineering New York University New YorkNY United States School of Biomedical Engineering Health Science Center Shenzhen University Shenzhen China Lausanne Switzerland School of Biological Sciences University of Reading Reading United Kingdom Laboratoire de Chimie Bactérienne CNRS Université Aix Marseille UMR Institut de Microbiologie de la Méditerranée Marseille France Department of Internal Medicine I University Hospital Dresden Technical University Dresden Dresden Germany Else Kroener Fresenius Center for Digital Health Technical University Dresden Dresden Germany Department of Automation University of Science and Technology of China Hefei China Institute of Advanced Technology University of Science and Technology of China Hefei Chi
Cell segmentation is a critical step for quantitative single-cell analysis in microscopy images. Existing cell segmentation methods are often tailored to specific modalities or require manual interventions to specify ... 详细信息
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Chronic radiation-associated dysphagia in oropharyngeal cancer survivors: Towards age-adjusted dose constraints for deglutitive muscles
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CLINICAL AND TRANSLATIONAL RADIATION ONCOLOGY 2019年 18卷 16-22页
作者: Christopherson, Kaitlin M. Ghosh, Alokananda Sherif, Abdallah Mohamed, Radwan Kamal, Mona Fuller, David Department of Radiation Oncology The University of Texas MD Anderson Cancer Center Houston TX United States Department of Biostatistics and Data Science University of Texas School of Public Health Houston TX United States Department of Clinical Oncology University of Alexandria Alexandria Egypt Department of Emergency Medicine The University of Texas MD Anderson Cancer Center Houston TX United States Baylor College of Medicine Houston TX United States Athinoula A. Martinos Center for Biomedical Imaging Massachusetts General Hospital Charlestown MA United States Department of Radiation Oncology The University of Texas Medical Branch Galveston TX United States Department of Head and Neck Surgery The University of Texas MD Anderson Cancer Center Houston TX United States Department of Thoracic & Head and Neck Oncology The University of Texas MD Anderson Cancer Center Houston TX United States Medical Physics Program The University of Texas Graduate School of Biomedical Sciences Houston TX United States Department of Computer Science University of Illinois at Chicago Chicago IL United States Department of Electrical and Computer Engineering The University of Iowa Iowa City IA United States
Objectives: We sought to model chronic radiation-associated dysphagia (RAD) in patients given intensity-modulated radiation therapy (IMRT) for oropharyngeal squamous cell cancer (OPSCC) as a function of age and dose t... 详细信息
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OpenMM 8: Molecular Dynamics Simulation with Machine Learning Potentials
arXiv
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arXiv 2023年
作者: Eastman, Peter Galvelis, Raimondas Peláez, Raúl P. Abreu, Charlles R.A. Farr, Stephen E. Gallicchio, Emilio Gorenko, Anton Henry, Michael M. Hu, Frank Huang, Jing Krämer, Andreas Michel, Julien Mitchell, Joshua A. Pande, Vijay S. Rodrigues, João P.G.L.M. Rodriguez-Guerra, Jaime Simmonett, Andrew C. Singh, Sukrit Swails, Jason Turner, Philip Wang, Yuanqing Zhang, Ivy Chodera, John D. De Fabritiis, Gianni Markland, Thomas E. Department of Chemistry Stanford University StanfordCA94305 United States Acellera Labs C Dr Trueta 183 Barcelona08005 Spain C Dr. Aiguader 88 Barcelona08003 Spain Chemical Engineering Department School of Chemistry Federal University of Rio de Janeiro Rio de Janeiro68542 Brazil Redesign Science Inc. 180 Varick St. New YorkNY10014 United States EaStCHEM School of Chemistry University of Edinburgh EH9 3FJ United Kingdom Department of Chemistry and Biochemistry Brooklyn College The City University of New York NY United States Ph.D. Program in Chemistry Ph.D. Program in Biochemistry The Graduate Center of the City University of New York New YorkNY United States Stream HPC Koningin Wilhelminaplein 1 - 40601 Amsterdam1062 HG Netherlands Computational and Systems Biology Program Sloan Kettering Institute Memorial Sloan Kettering Cancer Center New YorkNY10065 United States Key Laboratory of Structural Biology of Zhejiang Province School of Life Sciences Westlake University 18 Shilongshan Road Zhejiang Hangzhou310024 China Department of Mathematics and Computer Science Freie Universität Berlin Arnimallee 12 Berlin14195 Germany The Open Force Field Initiative Open Molecular Software Foundation DavisCA95616 United States Andreessen Horowitz 2865 Sand Hill Rd Menlo ParkCA94025 United States Department of Structural Biology Stanford University StanfordCA94305 United States Charité Universitätsmedizin Berlin In silico Toxicology and Structural Bioinformatics Virchowweg 6 Berlin10117 Germany Laboratory of Computational Biology National Heart Lung and Blood Institute National Institutes of Health BethesdaMD20892 United States Entos Inc. 9310 Athena Circle La Jolla CA92037 United States College of Engineering Virginia Polytechnic Institute State University BlacksburgVA24061 United States Simons Center for Computational Physical Chemistry Center for Data Science New York University 24 Waverly Place New YorkNY10004 United States T
Machine learning plays an important and growing role in molecular simulation. The newest version of the OpenMM molecular dynamics toolkit introduces new features to support the use of machine learning potentials. Arbi... 详细信息
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415O Predictive factors of fertility in patients with breast cancer interrupting adjuvant endocrine therapy to attempt pregnancy in the POSITIVE trial
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ESMO Open 2025年 10卷 104987-104987页
作者: I. Demeestere S.M. Niman A.H. Partridge D. Diego R. Kammler M. Ruggeri M.A. Colleoni C. Shimizu C. Saura Manich K.A. Gelmon A. Satersdal J.R. Kroep A. Mailliez F. Amant T. Spanic S. El-Abed R.D. Gelber O. Pagani H.A. Azim F.A. Peccatori Research Laboratory on Human Reproduction ULB - Université Libre de Bruxelles Brussels Belgium Department of Data Science Dana-Farber Cancer Institute Boston MA United States of America Medical Oncology Dana-Farber Cancer Institute Boston United States of America Gynecology and Obstetrics Emory University Hospital Midtown Atlanta United States of America Translational Research Coordination Department ETOP IBCSG Partners Foundation Bern Switzerland IBCSG International Breast Cancer Study Group Bern Switzerland Division of Medical Senology IEO - Istituto Europeo di Oncologia Milan Italy Department of Breast and Medical Oncology NCGM - National Center for Global Health and Medicine Shinjuku-ku Japan Breast Cancer Program Vall d'Hebron University Hospital Barcelona Spain Department of Medical Oncology BC Cancer Agency - Vancouver Vancouver Canada Breast Cancer Unit Department of Oncology Oslo University Hospital Oslo Norway Medical Oncology Department LUMC-Leiden University Medical Center Leiden Netherlands Department of Medical Oncology Centre Oscar Lambret Lille France Gynaecology Unit UZ Leuven - University Hospitals Leuven - Campus Gasthuisberg Leuven Belgium Europa Donna Slovenia Europa Donna - Slovensko zdruzenje za boj proti raku dojk Ljubljana Slovenia Breast International Group Breast International Group (BIG) - AISBL Brussels Belgium Oncology HRC - Hopital Riviera-Chablais Rennaz Switzerland Medical Cairo Cure Oncology Center Cairo Egypt Department of Gynaecological Oncology IEO - Istituto Europeo di Oncologia IRCCS Milan Italy
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JS08.6.A A connectivity signature for glioblastoma
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Neuro-Oncology 2022年 第SUPPLEMENT_2期24卷 ii8-ii9页
作者: Hoffmann, D C Hai, L Wagener, R Mandelbaum, H Xie, R Hausmann, D Dominguez Azorín, D Weil, S Sievers, P Cebulla, G Ito, J Warnken, U Venkataramani, V Ernst, K Reibold, D Will, R Suvà, M L Herold-Mende, C Sahm, F Winkler, F Schlesner, M Wick, W Kessler, T Clinical Cooperation Unit Neurooncology German Cancer Consortium (DKTK) German Cancer Research Center (DKFZ) Heidelberg Germany Department of Neurology and Neurooncology Program National Center for Tumor Diseases Heidelberg University Hospital Heidelberg Germany Faculty of Biosciences Heidelberg University Heidelberg Germany Bioinformatics and Omics Data Analytics DKFZ Heidelberg Germany Department of Neuropathology Institute of Pathology University Hospital Heidelberg Heidelberg Germany Clinical Cooperation Unit Neuropathology DKTK DKFZ Heidelberg Germany Department of Neuroanatomy Institute for Anatomy and Cell Biology Heidelberg University Heidelberg Germany Hopp Children's Cancer Center at the NCT Heidelberg (KiTZ) Heidelberg Germany Division of Pediatric Neurooncology DKTK DKFZ Heidelberg Germany Genomics and Proteomics Core Facility DKTK DKFZ Heidelberg Germany Broad Institute of Harvard and MIT Cambridge MA United States Department of Pathology and Center for Cancer Research Massachusetts General Hospital and Harvard Medical School Boston MA United States Department of Neurosurgery Heidelberg University Hospital Heidelberg Germany Biomedical Informatics Data Mining and Data Analytics Faculty of Applied Computer Science and Medical Faculty University of Augsburg Augsburg Germany
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PTEN pathogenic variants are associated with poor prognosis in patients with advanced soft tissue sarcoma
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BJC reports 2024年 第1期2卷 9页
作者: Minggui Pan Maggie Y Zhou Chen Jiang Zheyang Zhang Nam Bui Jeffrey Bien Amanda Siy Ninah Achacoso Aleyda V Solorzano Pam Tse Elaine Chung Wenwei Hu Sachdev Thomas Kristen Ganjoo Laurel A Habel Division of Research Kaiser Permanente Oakland CA 94612 USA. minggui@stanford.edu. Sarcoma Program Division of Oncology Stanford University School of Medicine Stanford CA 94305 USA. minggui@stanford.edu. Sarcoma Program Division of Oncology Stanford University School of Medicine Stanford CA 94305 USA. Division of Research Kaiser Permanente Oakland CA 94612 USA. State Key Laboratory of Cellular Stress Biology School of Life Sciences Faculty of Medicine and Life Sciences Xiamen University Xiamen Fujian 361102 China. National Institute for Data Science in Health and Medicine Xiamen University Xiamen Fujian 361102 China. Rutger's Cancer Institute of New Jersey New Brunswick NJ 08903 USA. Department of Oncology and Hematology Kaiser Permanente Vallejo CA 94589 USA.
BACKGROUND:We aimed to examine whether PTEN pathogenic variants (mutPTEN) were associated with overall survival (OS) in patients with advanced soft tissue sarcoma (STS) with the presence of one or more of the most com...
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A robust multiplex-DIA workflow profiles protein turnover regulations associated with cisplatin resistance and aneuploidy
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Nature communications 2025年 第1期16卷 5034页
作者: Barbora Salovska Wenxue Li Oliver M Bernhardt Pierre-Luc Germain Qinyue Wang Tejas Gandhi Lukas Reiter Yansheng Liu Department of Pharmacology Yale University School of Medicine New Haven CT USA. Cancer Biology Institute Yale University School of Medicine West Haven CT USA. Biognosys AG Zurich-Schlieren Switzerland. Institute for Neuroscience Department of Health Sciences and Technology ETH Zurich Zurich Switzerland. Master Program of Public Health Department of Chronic Disease Epidemiology Yale School of Public Health New Haven CT USA. Department of Pharmacology Yale University School of Medicine New Haven CT USA. yansheng.liu@yale.edu. Cancer Biology Institute Yale University School of Medicine West Haven CT USA. yansheng.liu@yale.edu. Department of Biomedical Informatics & Data Science Yale University School of Medicine New Haven CT USA. yansheng.liu@yale.edu.
Quantifying protein turnover is fundamental to understanding cellular processes and advancing drug discovery. Multiplex-DIA mass spectrometry (MS), combined with dynamic SILAC labeling (pulse-SILAC, or pSILAC) reliabl...
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Author Correction: The landscape of viral associations in human cancers
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Nature genetics 2023年 第6期55卷 1077页
作者: Marc Zapatka Ivan Borozan Daniel S Brewer Murat Iskar Adam Grundhoff Malik Alawi Nikita Desai Holger Sültmann Holger Moch Colin S Cooper Roland Eils Vincent Ferretti Peter Lichter Division of Molecular Genetics German Cancer Research Center (DKFZ) Heidelberg Germany. Informatics and Bio-computing Program Ontario Institute for Cancer Research Toronto Ontario Canada. Norwich Medical School University of East Anglia Norwich UK. Earlham Institute Norwich UK. Heinrich-Pette-Institute Leibniz Institute for Experimental Virology Hamburg Germany. German Center for Infection Research (DZIF) Partner Site Hamburg-Borstel-Lübeck-Riems Hamburg Germany. Bioinformatics Core University Medical Center Hamburg-Eppendorf Hamburg Germany. Bioinformatics Group Department of Computer Science University College London London UK. Biomedical Data Science Laboratory Francis Crick Institute London UK. National Center for Tumor Diseases (NCT) Heidelberg Heidelberg Germany. Division of Cancer Genome Research German Cancer Research Center (DKFZ) Heidelberg Germany. German Cancer Consortium (DKTK) Heidelberg Germany. Department of Pathology and Molecular Pathology University and University Hospital Zürich Zurich Switzerland. Institute of Cancer Research London UK. University of East Anglia Norwich UK. Division of Theoretical Bioinformatics German Cancer Research Center (DKFZ) Heidelberg Germany. Department of Bioinformatics and Functional Genomics Institute of Pharmacy and Molecular Biotechnology Heidelberg University and BioQuant Center Heidelberg Germany. Center for Digital Health Berlin Institute of Health and Charité Universitätsmedizin Berlin Berlin Germany. Ontario Institute for Cancer Research MaRS Centre Toronto Ontario Canada. Department of Biochemistry and Molecular Medicine University of Montreal Montreal Québec Canada. Division of Molecular Genetics German Cancer Research Center (DKFZ) Heidelberg Germany. peter.lichter@dkfz-heidelberg.de. German Cancer Consortium (DKTK) Heidelberg Germany. peter.lichter@dkfz-heidelberg.de.
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Sustainability of Rideshare programs to Promote Engagement of Underrepresented Populations in Breast cancer Screening Trials.
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Journal of the American College of Radiology 2025年
作者: Bhavika K. Patel Jhenitza P. Raygoza Heidi E. Kosiorek Carmen C. Soto Diana Y. Grijalva Etta Pisano Donald Northfelt Suganya Karuppana Jessica D. Austin Professor of Radiology Department of Diagnostic Radiology Mayo Clinic Phoenix AZ. Data science Co-Chair for ACR Breast Imaging and ACR Breast Imaging Research Registry Program Coordinator Department of Quantitative Health Sciences Division of Epidemiology Mayo Clinic Scottsdale AZ. No ACR affiliation Assistant Professor of Biostatistics Department of Quantitative Health Sciences Division of Clinical Trials and Biostatistics Mayo Clinic Scottsdale AZ. No ACR affiliation Clinical Research Coordinator Mayo Clinic Comprehensive Cancer Center Cancer Clinical Research Office Phoenix AZ. No ACR affiliation Senior Director for Research Development Center for Research and Innovation American College of Radiology Philadelphia PA. ACR affiliation Professor of Medicine Division of Hematology/Oncology Mayo Clinic Phoenix AZ. No ACR affiliation Associate Chief Medical Officer Adelante Healthcare Phoenix AZ. No ACR affiliation Assistant Professor of Epidemiology Department of Quantitative Health Sciences Division of Epidemiology Mayo Clinic Scottsdale AZ. No ACR affiliation
Background Transportation barriers significantly limit participation in breast cancer screening trials among Hispanic women, exacerbating disparities in breast cancer outcomes and underrepresentation in clinical resea...
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