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检索条件"机构=Cancer Data Science Program"
252 条 记 录,以下是171-180 订阅
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Five-Year Outcomes of the “Abatacept Combined with a Calcineurin Inhibitor and Methotrexate for Graft Versus Host Disease (GVHD) Prophylaxis: A Randomized Controlled Trial” (‘ABA2‘)
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Blood 2024年 144卷 3516-3516页
作者: Lev Gorfinkel Muna Qayed Brandi Bratrude Kayla Betz Kyle Hebert Sung W. Choi Jeffrey Davis Christine Duncan Roger H. Giller Michael S. Grimley Andrew Harris David A Jacobsohn Nahal Lalefar Nosha Farhadfar Michael A. Pulsipher Shalini Shenoy Aleksandra Petrovic Kirk R. Schultz Gregory Yanik Bruce R Blazar Benjamin Watkins Division of Hematology-Oncology Boston Children's Hospital Boston MA Harvard Medical School Boston MA Dana-Farber Cancer Institute Boston MA Division of Pediatric Hematology Oncology and Bone Marrow Transplantation Aflac Cancer and Blood Disorders Center Children's Healthcare of Atlanta Atlanta GA Boston Children's Hospital Boston Boston Children's Hospital boston MA Department of Data Science Dana-Farber Cancer Institute Boston MA Blood and Marrow Transplantation Program University of Michigan Ann Arbor MI BC Children's Hospital Oak Harbor WA Division of Pediatric Hematology/Oncology Boston Children's Hospital Boston MA Department of Pediatric Oncology Dana-Farber Cancer Institute Boston MA Department of Pediatrics Harvard Medical School Boston MA University of Colorado SOM / Childrens Hospital Colorado Denver CO Cancer and Blood Diseases Institute Cincinnati Children's Hospital Medical Center Cincinnati OH Pediatric Stem Cell Transplantation and Cellular Therapies Service Department of Pediatrics Memorial Sloan Kettering Cancer Center New York NY Children's National Medical Center Washington DC UCSF Benioff Children's Hospital Oakland Oakland CA University of Florida Gainesville FL Huntsman Cancer Institute Salt Lake City UT Department of Pediatrics Division of Hematology / Oncology Washington University Medical Center Saint Louis MO Fred Hutchinson Cancer Center Seattle WA B.C. Children's Hospital Vancouver Canada Rogel Cancer Center University of Michigan Ann Arbor MI Division of Pediatric Blood and Marrow Transplantation University of Minnesota Minneapolis MN Tulane University New Orleans
Background: GVHD remains a major cause of non-relapse mortality (NRM) after hematopoietic cell transplant (HCT). Abatacept, a costimulatory blockade agent targeting the CD28:CD80/86 pathway, was FDA-approved in 2021 f...
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NGS-Based Copy Number Analysis in 1,185 Patients with Myeloid Neoplasms
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BLOOD 2016年 第22期128卷 955-955页
作者: Saiki, Ryunosuke Shiozawa, Yusuke Yoshizato, Tetsuichi Yoshida, Kenichi Shiraishi, Yuichi Tanaka, Hiroko Chiba, Kenichi Atsuta, Yoshiko Onizuka, Makoto Itonaga, Hidehiro Kanda, Yoshinobu Sekeres, Mikkael A. Guinta, Kathryn M. Miyawaki, Shuichi Nakamaki, Tsuyoshi Chiba, Shigeru Shih, Lee-Yung Miyazaki, Yasushi Miyano, Satoru Makishima, Hideki Maciejewski, Jaroslaw P. Ogawa, Seishi Department of Pathology and Tumor Biology Graduate School of Medicine Kyoto University Kyoto Japan Department of Pediatrics Graduate School of Medicine The University of Tokyo Tokyo Japan Human Genome Center Institute of Medical Science The University of Tokyo Tokyo Japan Laboratory of DNA information Analysis & Laboratory of Sequence Analysis Human Genome Center The University of Tokyo Tokyo Japan Japanese Data Center for Hematopoietic Cell Transplantation Nagoya Japan Nagoya University Graduate School of Medicine Nagoya Japan Department of Hematology and Oncology Tokai University School of Medicine Isehara Japan Department of Hematology Atomic Bomb Disease and Hibakusha Medicine Unit Atomic Bomb Disease Institute Nagasaki University Nagasaki Japan Division of Hematology Saitama Medical Center Jichi Medical University Saitama Japan Department of Translational Hematology and Oncology Research Taussig Cancer Institute Cleveland Clinic Cleveland OH Leukemia Program Department of Hematology and Medical Oncology Cleveland Clinic Cleveland OH Division of Hematology Tokyo Metropolitan Ohtsuka Hospital Tokyo Japan Department of Hematology Showa University School of Medicine Tokyo Japan Department of Hematology Faculty of Medicine University of Tsukuba Tsukuba Japan Division of Hematology-Oncology Department of Internal Medicine Chang Gung Memorial Hospital Chang Gung University Taoyuan Taiwan
955
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Correction to: Required concentration index quantifies effective drug combinations against hepatitis C virus infection
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Theoretical biology & medical modelling 2021年 第1期18卷 5页
作者: Yusuke Kakizoe Yoshiki Koizumi Yukino Ikoma Hirofumi Ohashi Takaji Wakita Shingo Iwami Koichi Watashi Department of Biology Faculty of Sciences Kyushu University Fukuoka 812-8581 Japan. Present address: Data Science Group Advanced Technology Division INTAGE Inc Tokyo 101-8201 Japan. National Center for Global Health and Medicine Tokyo 162-8655 Japan. Department of Virology II National Institute of Infectious Diseases Tokyo 162-8640 Japan. Department of Applied Biological Science Tokyo University of Science Noda 278-8510 Japan. Department of Biology Faculty of Sciences Kyushu University Fukuoka 812-8581 Japan. siwami@***. Institute for the Advanced Study of Human Biology (ASHBi) Kyoto University Kyoto 606-8501 Japan. siwami@***. NEXT-Ganken Program Japanese Foundation for Cancer Research (JFCR) Tokyo 135-8550 Japan. siwami@***. Science Groove Inc Fukuoka Japan. siwami@***. Department of Virology II National Institute of Infectious Diseases Tokyo 162-8640 Japan. kwatashi@nih.go.jp. Department of Applied Biological Science Tokyo University of Science Noda 278-8510 Japan. kwatashi@nih.go.jp. Institute for the Advanced Study of Human Biology (ASHBi) Kyoto University Kyoto 606-8501 Japan. kwatashi@nih.go.jp. NEXT-Ganken Program Japanese Foundation for Cancer Research (JFCR) Tokyo 135-8550 Japan. kwatashi@nih.go.jp. Institute for Frontier Life and Medical Sciences Kyoto University Kyoto Japan. kwatashi@nih.go.jp.
An amendment to this paper has been published and can be accessed via the original article.
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Classification of datasets with imputed missing values: does imputation quality matter?
arXiv
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arXiv 2022年
作者: Shadbahr, Tolou Roberts, Michael Stanczuk, Jan Gilbey, Julian Teare, Philip Dittmer, Sören Thorpe, Matthew Torné, Ramon Viñas Sala, Evis Lió, Pietro Patel, Mishal Rudd, James H.F. Mirtti, Tuomas Rannikko, Antti Sakari Aston, John A.D. Tang, Jing Schönlieb, Carola-Bibiane Selby, Ian Breger, Anna Weir-McCall, Jonathan R. Gkrania-Klotsas, Effrossyni Korhonen, Anna Jefferson, Emily Langs, Georg Yang, Guang Prosch, Helmut Preller, Jacobus Stanczuk, Jan Babar, Judith Sánchez, Lorena Escudero Wassin, Marcel Holzer, Markus Walton, Nicholas Research Program in Systems Oncology Faculty of Medicine University of Helsinki Helsinki Finland Department of Applied Mathematics and Theoretical Physics University of Cambridge Cambridge United Kingdom Data Science & Artificial Intelligence AstraZeneca Cambridge United Kingdom Department of Mathematics University of Manchester Manchester United Kingdom Department of Computer Science and Technology University of Cambridge Cambridge United Kingdom Department of Radiology University of Cambridge Cambridge United Kingdom Clinical Pharmacology & Safety Sciences AstraZeneca Cambridge United Kingdom Department of Medicine University of Cambridge Cambridge United Kingdom Department of Pathology University of Helsinki Helsinki University Hospital Finland iCAN-Digital Precision Cancer Medicine Flagship Helsinki Finland Department of Urology University of Helsinki Helsinki University Hospital Helsinki Finland Department of Pure Mathematics and Mathematical Statistics University of Cambridge Cambridge United Kingdom ZeTeM University of Bremen Bremen Germany Faculty of Mathematics University of Vienna Austria Royal Papworth Hospital Cambridge Royal Papworth Hospital NHS Foundation Trust Cambridge United Kingdom Addenbrooke’s Hospital Cambridge University Hospitals NHS Trust Cambridge United Kingdom Language Technology Laboratory University of Cambridge Cambridge United Kingdom Population Health and Genomics School of Medicine University of Dundee Dundee United Kingdom Department of Biomedical Imaging and Image-guided Therapy Computational Imaging Research Lab Medical University of Vienna Vienna Austria National Heart and Lung Institute Imperial College London London United Kingdom Contextflow GmbH Vienna Austria Institute of Astronomy University of Cambridge Cambridge United Kingdom
Classifying samples in incomplete datasets is a common aim for machine learning practitioners, but is non-trivial. Missing data is found in most real-world datasets and these missing values are typically imputed using... 详细信息
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Do Hematopoietic Cell Transplant Patients Treated on a Clinical Trial Do Better? Comparison of Characteristics and Outcomes of Patients Enrolled Versus Not Enrolled on Blood and Marrow Transplant Clinical Trials Network (BMT-CTN) 0201 Trial
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Blood 2014年 第21期124卷 209-209页
作者: Nandita Khera Navneet S. Majhail Ruta Brazauskas Zhiwei Wang Mahmoud Aljurf Görgün Akpek Yoshiko Atsuta Sara Beattie Christopher N. Bredeson Linda J. Burns Allen R. Chen Jason Dehn César O Freytes Vikas Gupta Gregory A. Hale Yoshihiro Inamoto Hillard M. Lazarus Charles F. LeMaistre Jeanne M. Palmer Kristjan Paulson Stephanie J. Lee Mayo Clinic Arizona Phoenix AZ Cleveland Clinic Cleveland OH Medical College of Wisconsin Milwaukee WI King Faisal Specialist Hospital and Research Centre Riyadh Saudi Arabia Section of Hematology Oncology Gilbert AZ Japanese Data Center for Hematopoietic Cell Transplantation Nagoya Japan University of Ottawa Ottawa Canada The Ottawa Hospital Ottawa Canada University of Minnesota Minneapolis MN Johns Hopkins University Baltimore MD National Marrow Donor Program Minneapolis MN University of Texas Health Science Center at San Antonio San Antonio TX Princess Margaret Cancer Centre University of Toronto Toronto Canada All Children’s Hospital St. Petersburg FL Fred Hutchinson Cancer Research Center Seattle WA University Hospitals Seidman Cancer Center and Case Western Reserve University Cleveland OH Sarah Cannon Nashville TN Mayo Clinic Arizona and Phoenix Children’s Hospital Phoenix AZ CancerCare Manitoba University of Manitoba Winnipeg Canada
Background: The association of clinical trial participation with outcomes in cancer patients is controversial, with some studies reporting better outcomes for trial participants while others do not. It is possible tha...
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QU-BraTS: MICCAI BraTS 2020 Challenge on Quantifying Uncertainty in Brain Tumor Segmentation - Analysis of Ranking Scores and Benchmarking Results
arXiv
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arXiv 2021年
作者: Mehta, Raghav Filos, Angelos Baid, Ujjwal Sako, Chiharu McKinley, Richard Rebsamen, Michael Dätwyler, Katrin Meier, Raphael Radojewski, Piotr Murugesan, Gowtham Krishnan Nalawade, Sahil Ganesh, Chandan Wagner, Ben Yu, Fang F. Fei, Baowei Madhuranthakam, Ananth J. Maldjian, Joseph A. Daza, Laura Gómez, Catalina Arbeláez, Pablo Dai, Chengliang Wang, Shuo Reynaud, Hadrien Mo, Yuanhan Angelini, Elsa Guo, Yike Bai, Wenjia Banerjee, Subhashis Pei, Linmin Murat, A.K. Rosas-González, Sarahi Zemmoura, Ilyess Tauber, Clovis Vu, Minh H. Nyholm, Tufve Löfstedt, Tommy Ballestar, Laura Mora Vilaplana, Veronica McHugh, Hugh Talou, Gonzalo Maso Wang, Alan Patel, Jay Chang, Ken Hoebel, Katharina Gidwani, Mishka Arun, Nishanth Gupta, Sharut Aggarwal, Mehak Singh, Praveer Gerstner, Elizabeth R. Kalpathy-Cramer, Jayashree Boutry, Nicolas Huard, Alexis Vidyaratne, Lasitha Rahman, Md Monibor Iftekharuddin, Khan M. Chazalon, Joseph Puybareau, Elodie Tochon, Guillaume Ma, Jun Cabezas, Mariano Llado, Xavier Oliver, Arnau Valencia, Liliana Valverde, Sergi Amian, Mehdi Soltaninejad, Mohammadreza Myronenko, Andriy Hatamizadeh, Ali Feng, Xue Dou, Quan Tustison, Nicholas Meyer, Craig Shah, Nisarg A. Talbar, Sanjay Weber, Marc-André Mahajan, Abhishek Jakab, Andras Wiest, Roland Fathallah-Shaykh, Hassan M. Nazeri, Arash Milchenko, Mikhail Marcus, Daniel Kotrotsou, Aikaterini Colen, Rivka Freymann, John Kirby, Justin Davatzikos, Christos Menze, Bjoern Bakas, Spyridon Gal, Yarin Arbel, Tal McGill University MontrealQC Canada Group University of Oxford Oxford United Kingdom University of Pennsylvania PhiladelphiaPA United States Department of Radiology Perelman School of Medicine The University of Pennsylvania PhiladelphiaPA United States Department of Pathology and Laboratory Medicine Perelman School of Medicine University of Pennsylvania PhiladelphiaPA United States University Institute of Diagnostic and Interventional Neuroradiology University of Bern Inselspital Bern University Hospital Bern Switzerland Department of Radiology University of Texas Southwestern Medical Center DallasTX United States Department of Bioengineering University of Texas DallasTX United States Advanced Imaging Research Center University of Texas Southwestern Medical Center DallasTX United States Universidad de los Andes Bogotá Colombia Data Science Institute Imperial College London London United Kingdom NIHR Imperial BRC ITMAT Data Science Group Imperial College London London United Kingdom Department of Brain Sciences Imperial College London London United Kingdom Machine Intelligence Unit Indian Statistical Institute Kolkata India Department of CSE University of Calcutta Kolkata India Department of Information Technology Uppsala University Uppsala Sweden Department of Diagnostic Radiology The University of Pittsburgh Medical Center PittsburghPA United States UMR U1253 iBrain Université de Tours Inserm Tours France Department of Radiation Sciences Umeå University Umeå Sweden Department of Computing Science Umeå University Umeå Sweden Signal Theory and Communications Department Universitat Politècnica de Catalunya Barcelona Tech Barcelona Spain Faculty of Medical and Health Sciences University of Auckland Auckland New Zealand Radiology Department Auckland City Hospital Auckland New Zealand Auckland Bioengineering Institute University of Auckland New Zealand Athinoula A. Martinos Center for Biomedical Imaging Department of Radiology
Deep learning (DL) models have provided state-of-the-art performance in various medical imaging benchmarking challenges, including the Brain Tumor Segmentation (BraTS) challenges. However, the task of focal pathology ... 详细信息
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Africa-specific human genetic variation near CHD1L associates with HIV-1 load (vol 620, pg 1025, 2023)
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NATURE 2023年 第7979期621卷 E42-E42页
作者: McLaren, Paul J. Porreca, Immacolata Iaconis, Gennaro Mok, Hoi Ping Mukhopadhyay, Subhankar Karakoc, Emre Cristinelli, Sara Pomilla, Cristina Bartha, Istvan Thorball, Christian W. Tough, Riley H. Angelino, Paolo Kiar, Cher S. Carstensen, Tommy Fatumo, Segun Porter, Tarryn Jarvis, Isobel Skarnes, William C. Bassett, Andrew DeGorter, Marianne K. Moorthy, Mohana Prasad Sathya Tuff, Jeffrey F. Kim, Eun-Young Walter, Miriam Simons, Lacy M. Bashirova, Arman Buchbinder, Susan Carrington, Mary Cossarizza, Andrea De Luca, Andrea Goedert, James J. Goldstein, David B. Haas, David W. Herbeck, Joshua T. Johnson, Eric O. Kaleebu, Pontiano Kilembe, William Kirk, Gregory D. Kootstra, Neeltje A. Kral, Alex H. Lambotte, Olivier Luo, Ma Mallal, Simon Martinez-Picado, Javier Meyer, Laurence Miro, Jose M. Moodley, Pravi Motala, Ayesha A. Mullins, James I. Nam, Kireem Obel, Niels Pirie, Fraser Plummer, Francis A. Poli, Guido Price, Matthew A. Rauch, Andri Theodorou, Ioannis Trkola, Alexandra Walker, Bruce D. Winkler, Cheryl A. Zagury, Jean-Francois Montgomery, Stephen B. Ciuffi, Angela Hultquist, Judd F. Wolinsky, Steven M. Dougan, Gordon Lever, Andrew M. L. Gurdasani, Deepti Groom, Harriet Sandhu, Manjinder S. Fellay, Jacques Sexually Transmitted and Blood-Borne Infections Division at JC Wilt Infectious Diseases Research Centre National Microbiology Laboratory Branch Public Health Agency of Canada Winnipeg Manitoba Canada Department of Medical Microbiology and Infectious Diseases University of Manitoba Winnipeg Manitoba Canada Vaccine and Therapeutics Laboratory Medical and Scientific Affairs National Microbiology Laboratory Branch Public Health Agency of Canada Winnipeg Manitoba Canada Wellcome Trust Sanger Institute Hinxton UK Department of Medicine University of Cambridge Cambridge UK Department of Medicine National University of Singapore Singapore Singapore Peter Gorer Department of Immunobiology School of Immunology and Microbial Sciences King’s College London London UK Institute of Microbiology Lausanne University Hospital and University of Lausanne Lausanne Switzerland Global Health Institute School of Life Sciences École Polytechnique Fédérale de Lausanne Lausanne Switzerland Swiss Institute of Bioinformatics Lausanne Switzerland Precision Medicine Unit Biomedical Data Science Center Lausanne University Hospital (CHUV) and University of Lausanne Lausanne Switzerland The African Computational Genomics (TACG) Research Group MRC/UVRI and LSHTM Uganda Research Unit Entebbe Uganda Department of Non-Communicable Disease Epidemiology Faculty of Epidemiology and Population Health London School of Hygiene and Tropical Medicine London UK The Jackson Laboratory for Genomic Medicine Farmington CT USA Department of Pathology Stanford University School of Medicine Stanford CA USA Department of Genetics Stanford University School of Medicine Stanford CA USA Division of Infectious Diseases Feinberg School of Medicine Northwestern University Chicago IL USA Basic Science Program Frederick National Laboratory for Cancer Research National Cancer Institute Frederick MD USA Laboratory of Integrative Cancer Immunology Center for Cancer Research National Cancer Institute Bethesda
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Corrigendum to "Identification of Differential Tumor Subtypes of T1 Bladder cancer" [Eur. Urol. 78 (2020) 533-537]
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European urology 2022年 第2期81卷 e53页
作者: A Gordon Robertson Clarice S Groeneveld Brian Jordan Xiaoqi Lin Kimberly A McLaughlin Arighno Das Leigh Ann Fall Damiano Fantini Timothy J Taxter Lauren S Mogil Sia Viborg Lindskrog Lars Dyrskjøt David J McConkey Robert S Svatek Aurélien de Reyniès Mauro A A Castro Joshua J Meeks Dxige Research Inc. Courtenay BC Canada. Cartes d'Identité des Tumeurs Program Ligue Nationale Contre le Cancer Paris France Oncologie Moleculaire Institut Curie Equipe Labellisée Ligue Contre le Cancer Paris France. Department of Urology University of Washington Seattle WA USA. Department of Pathology Northwestern University Feinberg School of Medicine Chicago IL USA. Departments of Urology Biochemistry and Molecular Genetics Feinberg School of Medicine Northwestern University Chicago IL USA. Tempus Labs Inc. Chicago IL USA. Center for Translational Data Science University of Chicago Chicago IL USA. Department of Molecular Medicine Aarhus University Hospital Aarhus Denmark. Johns Hopkins Greenberg Bladder Cancer Institute Brady Urological Institute Johns Hopkins University Baltimore MD USA. Experimental Developmental Therapeutics Program UT Health MD Anderson San Antonio TX USA Department of Urology UT Health San Antonio San Antonio TX USA. Cartes d'Identité des Tumeurs Program Ligue Nationale Contre le Cancer Paris France. Bioinformatics and Systems Biology Laboratory Federal University of Paraná Curitiba Brazil. Departments of Urology Biochemistry and Molecular Genetics Feinberg School of Medicine Northwestern University Chicago IL USA Jesse Brown VA Medical Center Chicago IL USA. Electronic address: joshua.meeks@northwestern.edu.
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SWEET: a single-sample network inference method for deciphering individual features in disease
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Briefings in bioinformatics 2023年 第2期24卷 bbad032页
作者: Hsin-Hua Chen Chun-Wei Hsueh Chia-Hwa Lee Ting-Yi Hao Tzu-Ying Tu Lan-Yun Chang Jih-Chin Lee Chun-Yu Lin Institute of Bioinformatics and Systems Biology National Yang Ming Chiao Tung University Hsinchu 300 Taiwan. School of Medical Laboratory Science and Biotechnology College of Medical Science and Technology Taipei Medical University Taipei 110 Taiwan. TMU Research Center of Cancer Translational Medicine Taipei Medical University Taipei 110 Taiwan. Ph.D. Program in Medical Biotechnology College of Medical Science and Technology Taipei Medical University Taipei Taiwan. Department of Otolaryngology-Head and Neck Surgery Tri-Service General Hospital National Defense Medical Center Taipei 110 Taiwan. Department of Biological Science and Technology National Yang Ming Chiao Tung University Hsinchu 300 Taiwan. Institute of Data Science and Engineering National Yang Ming Chiao Tung University Hsinchu 300 Taiwan. Center for Intelligent Drug Systems and Smart Bio-devices National Yang Ming Chiao Tung University Hsinchu 300 Taiwan. School of Dentistry Kaohsiung Medical University Kaohsiung 807 Taiwan.
Recently, extracting inherent biological system information (e.g. cellular networks) from genome-wide expression profiles for developing personalized diagnostic and therapeutic strategies has become increasingly impor... 详细信息
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PTEN pathogenic variants are associated with poor prognosis in patients with advanced soft tissue sarcoma
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BJC reports 2024年 第1期2卷 9页
作者: Minggui Pan Maggie Y Zhou Chen Jiang Zheyang Zhang Nam Bui Jeffrey Bien Amanda Siy Ninah Achacoso Aleyda V Solorzano Pam Tse Elaine Chung Wenwei Hu Sachdev Thomas Kristen Ganjoo Laurel A Habel Division of Research Kaiser Permanente Oakland CA 94612 USA. minggui@stanford.edu. Sarcoma Program Division of Oncology Stanford University School of Medicine Stanford CA 94305 USA. minggui@stanford.edu. Sarcoma Program Division of Oncology Stanford University School of Medicine Stanford CA 94305 USA. Division of Research Kaiser Permanente Oakland CA 94612 USA. State Key Laboratory of Cellular Stress Biology School of Life Sciences Faculty of Medicine and Life Sciences Xiamen University Xiamen Fujian 361102 China. National Institute for Data Science in Health and Medicine Xiamen University Xiamen Fujian 361102 China. Rutger's Cancer Institute of New Jersey New Brunswick NJ 08903 USA. Department of Oncology and Hematology Kaiser Permanente Vallejo CA 94589 USA.
BACKGROUND:We aimed to examine whether PTEN pathogenic variants (mutPTEN) were associated with overall survival (OS) in patients with advanced soft tissue sarcoma (STS) with the presence of one or more of the most com...
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