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检索条件"机构=Cancer Data Science Program"
252 条 记 录,以下是21-30 订阅
排序:
A General-Purpose Self-Supervised Model for Computational Pathology
arXiv
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arXiv 2023年
作者: Chen, Richard J. Ding, Tong Lu, Ming Y. Williamson, Drew F.K. Jaume, Guillaume Chen, Bowen Zhang, Andrew Shao, Daniel Song, Andrew H. Shaban, Muhammad Williams, Mane Vaidya, Anurag Sahai, Sharifa Oldenburg, Lukas Weishaupt, Luca L. Wang, Judy J. Williams, Walt Le, Long Phi Gerber, Georg Mahmood, Faisal Department of Pathology Brigham and Women’s Hospital Harvard Medical School BostonMA United States Department of Pathology Massachusetts General Hospital Harvard Medical School BostonMA United States Cancer Program Broad Institute of Harvard MIT CambridgeMA United States Cancer Data Science Program Dana-Farber Cancer Institute BostonMA United States Department of Biomedical Informatics Harvard Medical School BostonMA United States CambridgeMA United States Health Sciences and Technology Harvard-MIT CambridgeMA United States Harvard John A. Paulson School of Engineering And Applied Sciences Harvard University CambridgeMA United States Department of Systems Biology Harvard University CambridgeMA United States Harvard Data Science Initiative Harvard University CambridgeMA United States
Tissue phenotyping is a fundamental computational pathology (CPath) task in learning objective characterizations of histopathologic biomarkers in anatomic pathology. However, whole-slide imaging (WSI) poses a complex ... 详细信息
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Deciphering colorectal cancer genetics through multi-omic analysis of 100,204 cases and 154,587 controls of European and east Asian ancestries (vol 55, pg 89, 2023)
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NATURE GENETICS 2023年 第3期55卷 519-520页
作者: Fernandez-Rozadilla, Ceres Timofeeva, Maria Chen, Zhishan Law, Philip Thomas, Minta Schmit, Stephanie Diez-Obrero, Virginia Hsu, Li Fernandez-Tajes, Juan Palles, Claire Sherwood, Kitty Briggs, Sarah Svinti, Victoria Donnelly, Kevin Farrington, Susan Blackmur, James Vaughan-Shaw, Peter Shu, Xiao-ou Long, Jirong Cai, Qiuyin Guo, Xingyi Lu, Yingchang Broderick, Peter Studd, James Huyghe, Jeroen Harrison, Tabitha Conti, David Dampier, Christopher Devall, Mathew Schumacher, Fredrick Melas, Marilena Rennert, Gad Obon-Santacana, Mireia Martin-Sanchez, Vicente Moratalla-Navarro, Ferran Oh, Jae Hwan Kim, Jeongseon Jee, Sun Ha Jung, Keum Ji Kweon, Sun-Seog Shin, Min-Ho Shin, Aesun Ahn, Yoon-Ok Kim, Dong-Hyun Oze, Isao Wen, Wanqing Matsuo, Keitaro Matsuda, Koichi Tanikawa, Chizu Ren, Zefang Gao, Yu-Tang Jia, Wei-Hua Hopper, John Jenkins, Mark Win, Aung Ko Pai, Rish Figueiredo, Jane Haile, Robert Gallinger, Steven Woods, Michael Newcomb, Polly Duggan, David Cheadle, Jeremy Kaplan, Richard Maughan, Timothy Kerr, Rachel Kerr, David Kirac, Iva Bohm, Jan Mecklin, Lukka-Pekka Jousilahti, Pekka Knekt, Paul Aaltonen, Lauri Rissanen, Harri Pukkala, Eero Eriksson, Johan Cajuso, Tatiana Hanninen, Ulrika Kondelin, Johanna Palin, Kimmo Tanskanen, Tomas Renkonen-Sinisalo, Laura Zanke, Brent Mannisto, Satu Albanes, Demetrius Weinstein, Stephanie Ruiz-Narvaez, Edward Palmer, Julie Buchanan, Daniel Platz, Elizabeth Visvanathan, Kala Ulrich, Cornelia Siegel, Erin Brezina, Stefanie Gsur, Andrea Campbell, Peter Chang-Claude, Jenny Hoffmeister, Michael Brenner, Hermann Slattery, Martha Potter, John Tsilidis, Konstantinos Schulze, Matthias Gunter, Marc Murphy, Neil Castells, Antoni Castellvi-Bel, Sergi Moreira, Leticia Arndt, Volker Shcherbina, Anna Stern, Mariana Pardamean, Bens Bishop, Timothy Giles, Graham Southey, Melissa Idos, Gregory McDonnell, Kevin Abu-Ful, Zomoroda Greenson, Joel Shulman, Katerina Lejbkowicz, Flavio Offit, Kenneth Su, Yu-Ru Steinfelder, Robert Keku, Temitope van Guelpen, Bethany Hudson, Thomas Hampel, Heather Pearlman, Edinburgh Cancer Research Centre Institute of Genomics and Cancer University of Edinburgh Edinburgh UK Genomic Medicine Group Instituto de Investigacion Sanitaria de Santiago Santiago de Compostela Spain Colon Cancer Genetics Group Medical Research Council Human Genetics Unit Institute of Genetics and Cancer University of Edinburgh Edinburgh UK Danish Institute for Advanced Study Department of Public Health University of Southern Denmark Odense Denmark Division of Epidemiology Department of Medicine Vanderbilt-Ingram Cancer Center Vanderbilt Epidemiology Center Vanderbilt University Medical Center Nashville TN USA Division of Genetics and Epidemiology Institute of Cancer Research London UK Public Health Sciences Division Fred Hutchinson Cancer Research Center Seattle WA USA Genomic Medicine Institute Cleveland Clinic Cleveland OH USA Population and Cancer Prevention Program Case Comprehensive Cancer Center Cleveland OH USA Colorectal Cancer Group ONCOBELL Program Bellvitge Biomedical Research Institute Barcelona Spain Oncology Data Analytics Program Catalan Institute of Oncology Barcelona Spain Consortium for Biomedical Research in Epidemiology and Public Health Madrid Madrid Spain Department of Clinical Sciences Faculty of Medicine University of Barcelona Barcelona Spain Department of Biostatistics School of Public Health University of Washington Seattle WA USA Institute of Cancer and Genomic Sciences College of Medical and Dental Sciences University of Birmingham Birmingham UK Department of Public Health Richard Doll Building University of Oxford Oxford UK Department of Biomedical Informatics Vanderbilt University School of Medicine Nashville TN USA Department of Preventive Medicine USC Norris Comprehensive Cancer Center Keck School of Medicine University of Southern California Los Angeles CA USA Center for Public Health Genomics Department of Public Health Sciences University of Virginia Charlottesville VA USA Department of Populat
Colorectal cancer (CRC) is a leading cause of mortality worldwide. We conducted a genome-wide association study meta-analysis of 100,204 CRC cases and 154,587 controls of European and east Asian ancestry, identifying ... 详细信息
来源: 评论
Weakly Supervised Joint Whole-Slide Segmentation and Classification in Prostate cancer
arXiv
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arXiv 2023年
作者: Pati, Pushpak Jaume, Guillaume Ayadi, Zeineb Thandiackal, Kevin Bozorgtabar, Behzad Gabrani, Maria Goksel, Orcun IBM Research Europe Switzerland Department of Pathology Brigham and Women’s Hospital Harvard Medical School United States Department of Pathology Massachusetts General Hospital Harvard Medical School United States Cancer Program Broad Institute of Harvard MIT United States Data Science Program Dana-Farber Harvard Cancer Center United States Computer-Assisted Applications in Medicine ETH Zurich Switzerland Signal Processing Laboratory 5 EPFL Switzerland EPFL Switzerland Department of Information Technology Uppsala University Sweden
The segmentation and automatic identification of histological regions of diagnostic interest offer a valuable aid to pathologists. However, segmentation methods are hampered by the difficulty of obtaining pixel-level ... 详细信息
来源: 评论
Language Enhanced Model for Eye (LEME): An Open-Source Ophthalmology-Specific Large Language Model
arXiv
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arXiv 2024年
作者: Gilson, Aidan Ai, Xuguang Xie, Qianqian Srinivasan, Sahana Pushpanathan, Krithi Singer, Maxwell B. Huang, Jimin Kim, Hyunjae Long, Erping Wan, Peixing Del Priore, Luciano V. Ohno-Machado, Lucila Xu, Hua Liu, Dianbo Adelman, Ron A. Tham, Yih-Chung Chen, Qingyu Department of Ophthalmology Massachusetts Eye and Ear Harvard Medical School BostonMA United States Department of Biomedical Informatics and Data Science Yale School of Medicine Yale University New Haven United States Singapore Eye Research Institute Singapore National Eye Centre Singapore Centre for Innovation and Precision Eye Health Department of Ophthalmology Yong Loo Lin School of Medicine National University of Singapore Singapore Department of Ophthalmology and Visual Science Yale School of Medicine Yale University New Haven United States Department of Computer Science Korea University 145 Anam-ro Seongbuk-gu Seoul02841 Korea Republic of Division of Cancer Epidemiology and Genetics National Cancer Institute National Institutes of Health BethesdaMD United States Center for Cancer Research National Cancer Institute National Institutes of Health BethesdaMD United States Ophthalmology and Visual Science Academic Clinical Program Duke-NUS Medical School Singapore Singapore
Large Language Models (LLMs) are poised to revolutionize healthcare. Ophthalmology-specific LLMs remain scarce and underexplored. We introduced an open-source, specialized LLM for ophthalmology, termed Language Enhanc... 详细信息
来源: 评论
The spatial zonation of the murine placental vasculature is specified by epigenetic mechanisms
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Developmental Cell 2025年 第10期60卷 1467-1482.e8页
作者: Gehrs, Stephanie Jakab, Moritz Gutjahr, Ewgenija Gu, Zuguang Weichenhan, Dieter Mallm, Jan-Philipp Mogler, Carolin Schlesner, Matthias Plass, Christoph Schlereth, Katharina Augustin, Hellmut G. Division of Vascular Oncology and Metastasis German Cancer Research Center (DKFZ) Heidelberg 69120 Germany European Center for Angioscience (ECAS) Medical Faculty Mannheim Heidelberg University Mannheim 68167 Germany Faculty of Biosciences Heidelberg University Heidelberg 69120 Germany Institute of Pathology University Clinic Heidelberg Heidelberg 69120 Germany Computational Oncology Group Molecular Precision Oncology Program National Center for Tumor Diseases (NCT) Heidelberg and German Cancer Research Center (DKFZ) Heidelberg 69120 Germany Division of Cancer Epigenomics German Cancer Research Center (DKFZ) Heidelberg 69120 Germany Division of Chromatin Networks German Cancer Research Center (DKFZ) and Bioquant Heidelberg 69120 Germany Institute of Pathology TUM School of Medicine Technical University of Munich Munich 80333 Germany Biomedical Informatics Data Mining and Data Analytics Faculty of Applied Computer Science and Medical Faculty University of Augsburg Augsburg 86159 Germany
The labyrinthian fetoplacental capillary network is vital for proper nourishment of the developing embryo. Dysfunction of the maternal-fetal circulation is a primary cause of placental insufficiency. Here, we show tha... 详细信息
来源: 评论
Artificial Intelligence for Digital and Computational Pathology
arXiv
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arXiv 2023年
作者: Song, Andrew H. Jaume, Guillaume Williamson, Drew F.K. Lu, Ming Y. Vaidya, Anurag Miller, Tiffany R. Mahmood, Faisal Department of Pathology Brigham and Women's Hospital Harvard Medical School BostonMA United States Department of Pathology Massachusetts General Hospital Harvard Medical School BostonMA United States Cancer Program Broad Institute of Harvard and MIT CambridgeMA United States Data Science Program Dana-Farber Cancer Institute BostonMA United States Department of Electrical Engineering and Computer Science Massachusetts Institute of Technology CambridgeMA United States Harvard-MIT Division of Health Sciences and Technology Massachusetts Institute of Technology CambridgeMA United States Harvard Medical School BostonMA United States
Advances in digitizing tissue slides and the fast-paced progress in artificial intelligence, including deep learning, have boosted the field of computational pathology. This field holds tremendous potential to automat... 详细信息
来源: 评论
Narrowing of the Racial Disparities Gap in Survival of Patients With Mycosis Fungoides: A Longitudinal Analysis of the SEER database
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Clinical Lymphoma, Myeloma and Leukemia 2025年
作者: Le, Britney Soror, Noha Ismail, Hamid D. Baker, Mohammed Shetayyah, Salman Abu Chung, Catherine G. William, Basem M. Ohio University Heritage College of Osteopathic Medicine Dublin OH The University of Oklahoma College of Medicine Oklahoma City OK United States Department of Computational Data Science and Engineering North Carolina Agricultural and Technical State University Greensboro NC United States Faculty of Medicine Jordan University of Science and Technology Irbid Jordan The Ohio State University Comprehensive Cancer Center: Arthur G. James Cancer Hospital and Richard J. Solove Research Institute Division of Dermatology Columbus OH Ohio Health Blood and Marrow Transplant Program Columbus OH
Background: Mycosis fungoides (MF) is the commonest subtype of cutaneous T-cell lymphoma. In the United States, prior studies reported that African Americans (AA) with MF had poor outcomes. data characterizing differe... 详细信息
来源: 评论
Towards a Visual-Language Foundation Model for Computational Pathology
arXiv
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arXiv 2023年
作者: Lu, Ming Y. Chen, Bowen Williamson, Drew F.K. Chen, Richard J. Liang, Ivy Ding, Tong Jaume, Guillaume Odintsov, Igor Zhang, Andrew Le, Long Phi Gerber, Georg Parwani, Anil V. Mahmood, Faisal Department of Pathology Brigham and Women’s Hospital Harvard Medical School BostonMA United States Department of Pathology Massachusetts General Hospital Harvard Medical School BostonMA United States Cancer Program Broad Institute of Harvard and MIT CambridgeMA United States Cancer Data Science Program Dana-Farber Cancer Institute BostonMA United States Department of Biomedical Informatics Harvard Medical School BostonMA United States CambridgeMA United States Health Sciences and Technology Harvard-MIT CambridgeMA United States Harvard John A. Paulson School of Engineering And Applied Sciences Harvard University CambridgeMA United States Department of Pathology Wexner Medical Center Ohio State University ColumbusOH United States Harvard Data Science Initiative Harvard University CambridgeMA United States
The accelerated adoption of digital pathology and advances in deep learning have enabled the development of powerful models for various pathology tasks across a diverse array of diseases and patient cohorts1–13. Howe... 详细信息
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Locla: A Novel Local Optimization Tool for Chromosome-Level Assembly of Multiple Sequencing Technologies
SSRN
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SSRN 2024年
作者: Chuang, Wei-Hsuan Cheng, Hsueh-Chien Chang, Yu-Jung Fu, Pao-Ying Huang, Yi-Chen Hsieh, Ping-Heng Lin, Chung-Yen Ho, Jan-Ming Chen, Shu-Hwa Wellcome Genome Campus United Kingdom Institute of Information Science Academia Sinica Taipei115 Taiwan Wellcome Sanger Institute Hinxton United Kingdom Ocean Data Bank Institute of Oceanography National Taiwan University Taipei10663 Taiwan Genome and Systems Biology Degree Program National Taiwan University Taipei10663 Taiwan Institute of Fisheries Science National Taiwan University Taipei10663 Taiwan TMU Research Center of Cancer Translational Medicine Taipei Medical University Taipei11031 Taiwan
LOCLA (Local Optimization for Chromosome-Level Assembly) is an innovative tool designed to enhance genome assemblies by addressing challenges in repetitive regions and alignment errors through iterative gap-filling. I... 详细信息
来源: 评论
Statistical Power Analysis for Designing Bulk, Single-Cell, and Spatial Transcriptomics Experiments: Review, Tutorial, and Perspectives
arXiv
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arXiv 2023年
作者: Jeon, Hyeongseon Xie, Juan Jeon, Yeseul Jung, Kyeong Joo Gupta, Arkobrato Chang, Won Chung, Dongjun Department of Biomedical Informatics The Ohio State University ColumbusOH United States Pelotonia Institute for Immuno-Oncology The James Comprehensive Cancer Center The Ohio State University ColumbusOH43210 United States The Interdisciplinary PhD program in Biostatistics The Ohio State University ColumbusOH United States Department of Statistics and Data Science Yonsei University Seoul Korea Republic of Department of Applied Statistics Yonsei University Seoul Korea Republic of Department of Computer Science and Engineering The Ohio State University ColumbusOH United States Division of Statistics and Data Science University of Cincinnati CincinnatiOH United States
Gene expression profiling technologies have been used in various applications such as cancer biology. The development of gene expression profiling has expanded the scope of target discovery in transcriptomic studies, ... 详细信息
来源: 评论