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检索条件"机构=Cell Programming Core Facility"
4 条 记 录,以下是1-10 订阅
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Generation of a homozygous DNMT3A knock-out hiPSC line for modeling of cardiovascular diseases associated with clonal hematopoiesis of indeterminate potential
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Stem cell Research 2025年 86卷 103707页
作者: Triantafyllou, Christos Peitz, Michael Fleischmann, Bernd K. Rieck, Sarah Institute of Physiology I University of Bonn Medical Faculty Bonn Germany Cell Programming Core Facility University of Bonn Medical Faculty Bonn Germany
Mutations associated with clonal hematopoiesis of indeterminate potential (CHIP) have been linked to cardiovascular disease (CVD), with DNA methyltransferase 3A (DNMT3A) being the most commonly mutated gene. (Jaiswal ...
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Automated CRISPR/Cas9-based genome editing of human pluripotent stem cells using the StemcellFactory
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Cytotherapy 2025年 第5期27卷 S36-S37页
作者: Nießing, B. Breitkreuz, Y. Elanzew, A. de Toledo, M.A.S. Vajs, P. Nolden, M. Erkens, F. Wanek, P. Yeung, S. Au Haupt, S. Koenig, N. Peitz, M. Schmitt, R. Zenke, M. Brustle, O. Bioadaptive Production Fraunhofer Institute for Production Technology IPT Aachen Germany Cellomics Unit LIFE&BRAIN GmbH Bonn Germany Institute of Reconstructive Neurobiology University of Bonn Medical Faculty and University Hospital Bonn Bonn Germany Institute for Biomedical Engineering Cell Biology Faculty of Medicine RWTH Aachen University Aachen Germany Helmholtz Institute for Biomedical Engineering RWTH Aachen University Aachen Germany Department of Medicine IV Hematology Oncology and Stem Cell Transplantation RWTH Aachen University Hospital Aachen Germany Center for Integrated Oncology Aachen Bonn Cologne Düsseldorf (CIO ABCD) Aachen Germany Fraunhofer Institute for Production Technology IPT Aachen Germany Cell Programming Core Facility University of Bonn Medical Faculty Bonn Germany Laboratory for Machine Tools and Production RWTH Aachen University Aachen Germany
Background & AimCRISPR/Cas9 technology is a leading method for efficient gene editing, enabling the creation of isogenic pairs of mutant and control human induced pluripotent stem cells (hiPSCs). While hiPSCs prov... 详细信息
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CHARACTERIZATION OF A NEW HUMAN NEURONAL MODEL FOR SYNGAP1 DISEASE
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IBRO Neuroscience Reports 2023年 15卷 S151-S152页
作者: Oriana Zerpa Rios Christina Au Yeung Alba Tristan-Noguero Diego Del Castillo-Berges Cristian De Quintana-Schmidt Michael Peitz Nerea Roher Oliver Brüstle Àlex Bayés Biomedical Research Institute Hospital Sant Pau Molecular Physiology Of The Synapse Barcelona Spain Universitat Autònoma de Barcelona Institut De Biotecnologia I De Biomedicina Barcelona Spain Universitat Autònoma de Barcelona Animal Physiology Unit (faculty Of Biosciences) Department Of Cellular Biology Physiology And Immunology Barcelona Spain University of Bonn School of Medicine & University Hospital Bonn Institute Of Reconstructive Neurobiology Life & Brain Center Bonn Germany Universitat de Barcelona Departament De Genètica Microbiologia I Estadística Facultat De Biologia Barcelona Spain University of Bonn School of Medicine Cell Programming Core Facility Bonn Germany Biomateriales y Nanomedicina (BBN) Ciber De Bioingenieria Barcelona Spain
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Recommendations, guidelines, and best practice for the use of human induced pluripotent stem cells for neuropharmacological studies of neuropsychiatric disorders
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Neuroscience Applied 2023年 2卷
作者: Dutan Polit, Lucia Eidhof, Ilse McNeill, Rhiannon V. Warre-Cornish, Katherine M. Yde Ohki, Cristine Marie Walter, Natalie Monet Sala, Carlo Verpelli, Chiara Radtke, Franziska Galderisi, Silvana Mucci, Armida Collo, Ginetta Edenhofer, Frank Castrén, Maija L. Réthelyi, János M. Ejlersen, Morten Hohmann, Sonja Simone Ilieva, Mirolyuba S. Lukjanska, Renate Matuleviciute, Rugile Michel, Tanja Maria de Vrij, Femke M.S. Kushner, Steven A. Lendemeijer, Bas Kittel-Schneider, Sarah Ziegler, Georg C. Gruber-Schoffnegger, Doris Pasterkamp, R. Jeroen Kasri, Amal Potier, Marie-Claude Knoblich, Jürgen A. Brüstle, Oliver Peitz, Michael Pich, Emilio Merlo Harwood, Adrian J. Abranches, Elsa Falk, Anna Vernon, Anthony C. Grünblatt, Edna Srivastava, Deepak P. Department of Basic and Clinical Neuroscience Institute of Psychiatry Psychology and Neuroscience King's College London London United Kingdom MRC Centre for Neurodevelopmental Disorders King's College London London United Kingdom Department of Neuroscience Karolinska Institutet Stockholm Sweden Department of Psychiatry Psychotherapy and Psychosomatic Medicine University Hospital University of Würzburg Würzburg D-97080 Germany National Institute for Biological Standards and Control South Mimms United Kingdom Department of Child and Adolescent Psychiatry and Psychotherapy Psychiatric University Hospital Zurich (PUK) University of Zurich Zürich Switzerland CNR Neuroscience Institute Milano Via Raoul Follereau 3 MB Vedano al Lambro 20854 Italy Department of Child and Adolescent Psychiatry University Hospital University of Wuerzburg Würzburg D-97080 Germany Department of Mental and Physical Health and Preventive Medicine University of Campania Luigi Vanvitelli Naples Italy Department of Molecular and Translational Medicine University of Brescia Viale Europa 11 Brescia 25123 Italy Department of Molecular Biology & CMBI Genomics Stem Cell Biology & Regenerative Medicine Group Leopold-Franzens-University Innsbruck Austria Medicum Department of Physiology University of Helsinki Helsinki Finland Department of Psychiatry and Psychotherapy Semmelweis University Budapest Hungary Department of Psychiatry Department of Clinical Research University of Southern Denmark and Psychiatry in the Region of Southern Denmark Odense University Hospital Odense Denmark Department of Psychiatry Erasmus University Medical Center Rotterdam Netherlands Department of Translational Neuroscience Evotec SE Essener Bogen 7 Hamburg D-22419 Germany Department of Translational Neuroscience University Medical Center Utrecht Brain Center Utrecht University Universiteitsweg 100 Utrecht 3584 CG Netherlands ICM Paris Brain Institute CNRS UMR7225 INSERM U1127 Sorbonne University Hôpit
The number of individuals suffering from neuropsychiatric disorders (NPDs) has increased worldwide, with 3 million disability-adjusted life-years calculated in 2019. Though research using various approaches including ... 详细信息
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