The degree of white matter (WM) myelination is rather inhomogeneous across the brain. As a consequence, white matter appears differently across the cortical lobes in MR images acquired during early postnatal developme...
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ISBN:
(纸本)9781424441273
The degree of white matter (WM) myelination is rather inhomogeneous across the brain. As a consequence, white matter appears differently across the cortical lobes in MR images acquired during early postnatal development. At 1 year old specifically, the gray/white matter contrast of MR images in prefrontal and temporal lobes is limited and thus tissue segmentation results show commonly reduce accuracy in these lobes. In this novel work, we propose the use of spatial intensity growth maps (IGM) for T1 and T2 weighted image to compensate for local appearance inhomogeneity. The IGM captures expected intensity changes from 1 to 2 years of age, as appearance inhomogeneity is highly reduced by the age of 24 months. For that purpose, we employ MRI data from a large dataset of longitudinal (12 and 24 month old subjects) MR study of Autism. The IGM creation is based on automatically co-registered images at 12 months, corresponding registered 24 months images, and a final registration of all image to a prior average template. In template space, voxelwise correspondence is thus achieved and the IGM is computed as the coefficient of a voxelwise linear regression model between corresponding intensities at 1-year and 2-years. The proposed IGM shows low regression values of 1-10% in GM and CSF regions, as well as in WM regions at advanced stage of myelination at 1-year. However, in the prefrontal and temporal lobe we observed regression values of 20-25%, indicating that the IGM appropriately captures the expected large intensity change in these lobes due to *** IGM is applied to cross-sectional MRI datasets of 1-year old subjects via registration, correction and tissue segmentation of the corrected dataset. We validated our approach in a small study of images with known, manual “ground truth” segmentations. We furthermore present an EM-like optimization of adapting existing non-optimal prior atlas probability maps to fit known expert rater segmentations.
Graphic process units (GPUs) are well suited to computing-intensive tasks and are among the fastest solutions to perform Computed Tomography (CT) reconstruction. As previous research shows, the bottleneck of GPU-imple...
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Graphic process units (GPUs) are well suited to computing-intensive tasks and are among the fastest solutions to perform Computed Tomography (CT) reconstruction. As previous research shows, the bottleneck of GPU-implementation is not the computational power, but the memory bandwidth. We propose a cache-aware memory-scheduling scheme for the back-projection, which can ensure a better load-balancing between GPU processors and the GPU memory. The proposed reshuffling method can be directly applied on existing GPU-accelerated CT reconstruction pipelines. The experimental results show that our optimization can achieve speedup ranging from 1.18-1.48. Our cache-optimization method is particular effective for low-resolution volumes with high resolution projections.
As the notion of Green computing becomes more popular in the IT world, new power saving features start to appear in both computer hardware and software. The difficulty of leveraging existing means of power management ...
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Process management systems play an important role for today's information systems. They coordinate the work items among employees and ensure the correct execution of processes. In this paper we focus on the organi...
A two-way textual entailment (TE) recognition system that uses lexical and syntactic features has been described in this paper. Thehybrid TEsystem is based on the Support Vector Machine that uses twenty three features...
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We present an Answer Validation System (AV) based on Textual Entailment and Question Answering. The important features used to develop the AV system are Named Entity Recognition, Textual Entailment, Question-Answer ty...
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The development of a parser based textual entailment system that is based on comparing the dependency relations in both the text and the hypothesis has been reported. The textual entailment system uses the CCG Parser ...
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In this paper we propose a new cause-effect non-symmetric measure applied to the task of Recognizing Textual *** we searched over a big corpus for sentences which contains the discourse marker "because" and ...
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Textual entailment has been recently defined as a common solution for modeling language variability in different NLP tasks. Textual Entailment is formally defined as a relationship between a coherent text T and a lang...
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Glycolysis is one of the most essential intracellular networks, found in a wide range of organisms. Due to its importance and due to its wide industrial applications, many experimental studies on all details of this p...
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Glycolysis is one of the most essential intracellular networks, found in a wide range of organisms. Due to its importance and due to its wide industrial applications, many experimental studies on all details of this process have been performed. Until now, however, to the best of our knowledge, there has been no comprehensive investigation of the robustness of this important process with respect to internal and external noise. To close this gap, we applied two complementary and mutually supporting approaches to a full-scale model of glycolysis in yeast: (a) a linear stability analysis based on a generalized modeling that deals only with those effective parameters of the system that are relevant for its stability, and (b) a numerical integration of the rate equations in the presence of noise, which accounts for imperfect mixing. The results suggest that the occurrence of metabolite oscillations in part of the parameter space is a side effect of the optimization of the system for maintaining a constant adenosine triphosphate level in the face of a varying energy demand and of fluctuations in the parameters and metabolite concentrations.
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