Context: Timely testing of women in labor with undocumented human immunodeficiency virus (HIV) status could enable immediate provision of antiretroviral ***: To determine the feasibility and acceptance of rapid HIV te...
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Context: Timely testing of women in labor with undocumented human immunodeficiency virus (HIV) status could enable immediate provision of antiretroviral ***: To determine the feasibility and acceptance of rapid HIV testing among women in labor and to assess rapid HIV assay performance. Design, Setting, and Patients: The Mother Infant Rapid Intervention At Delivery(MIRIAD) study implemented 24-hour counseling and voluntary rapid HIV testing for women in labor at 16 US hospitals from November 16, 2001, through November 15, 2003. A rapid HIV-1 antibody test for whole blood was used. Main Outcome Measures: Acceptance of HIV testing; sensitivity, specificity, and predictive value of the rapid test; time from blood collection to patient notification of results. Results: There were 91 707 visits to thelabor and delivery units in the study, 7381 of which were by eligible women without documentation of HIV *** these, 5744 (78%) women were approached for rapid HIV testing and 4849 (84%) consented. HIV-1 test results were positive for 34 women (prevalence=7/1000). Sensitivity and specificity of the rapid test were 100%and 99.9%, respectively; positive predictive value was 90%compared with 76%for enzyme immunoassay (EIA). Factors independently associated with higher test acceptance included younger age, being black or Hispanic,gestational age less than 32 weeks, and having had no prenatal care. Lower acceptance was associated with being admitted between 4 PM and midnight, particularly on Friday nights, but this may be explained in part by fewer available personnel. Median time from blood collection to patient notification of result was 66 minutes(interquartile range, 45-120 minutes), compared with 28 hours for EIA (P < .001). Conclusions: Rapid HIV testingis feasible and delivers accurate and timely test results for women in labor. It provides HIV positive women prompt access to intrapartum and neonatal antiretroviral prophylaxis,proven to reduce perin
The epidemiology of the HIV transmission in the United States has changed considerably since the epidemic began. Our increased understanding of the virus has fostered development of new treatments to prolong life, and...
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The HIV/std epidemics have broadened the need for better behavioral intervention programs and highlighted the importance of providing training in behavioral theory to frontline program practitioners. However, there is...
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Effective community-level HIV prevention strategies have the potential to reach large numbers of at-risk individuals at relatively small per-capita costs, and therefore to be highly cost-effective. We review the publi...
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Effective community-level HIV prevention strategies have the potential to reach large numbers of at-risk individuals at relatively small per-capita costs, and therefore to be highly cost-effective. We review the published literature on the cost-effectiveness of community-level HIV prevention interventions, including five studies of sexual behavior change interventions and seven risk reduction programs for injection drug users. Overall, these studies indicate that community-level strategies can be very cost-effective, and in many cases, actually save society money by averting the need for costly HIV/aids medical care.
The objective of this study was to evaluate the cost-effectiveness of a state-of-the-art sexual-risk reduction intervention for high-risk men and women. The main intervention consisted of seven small-group sessions ba...
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The objective of this study was to evaluate the cost-effectiveness of a state-of-the-art sexual-risk reduction intervention for high-risk men and women. The main intervention consisted of seven small-group sessions based on well-established principles of cognitive-behavioral therapy. This intervention was compared with a single-session video-based risk reduction intervention. The main outcome measure was the incremental cost-utility ratio, which equals the additional cost per additional quality-adjusted life year (QALY) saved by the cognitive-behavioral intervention, in comparison with the video intervention. A mathematical model of HIV transmission was used to translate reported sexual behavior changes into estimates of the number of HIV infections averted by the interventions, and associated savings in QALYs and averted HIV-related medical costs. For women, the incremental cost-utility ratio equaled $32,688 per QALY saved, which indicates that the cognitive-behavioral intervention was cost-effective compared to the video intervention. For men, the incremental cost-utility ratio was slightly negative, suggesting that the cognitive-behavioral intervention was highly cost-effective, or even cost-saving, compared to the video intervention. This analysis indicates that both brief and intensive sexual risk reduction interventions for high-risk populations can be cost-effective.
Objectives: To describe and analyze risk factors associatedwith disuse of condoms during commercial sexual intercourseamong clients attending sauna and massage ***: Selected female sex workers from saunas andbeauty pa...
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Objectives: To describe and analyze risk factors associatedwith disuse of condoms during commercial sexual intercourseamong clients attending sauna and massage ***: Selected female sex workers from saunas andbeauty parlors were trained as interviewers. They surveyedclients during provision of sexual services. Informationcollected included customers' demographics, knowledge ofstds, rationale for and history of condom use. Risk factorsfor condom usage were assessed though logistical ***: A total of 50 clients were interviewed. The rates ofcondom usage for last sexual intercourse with commercial andnon-commercial partners were 57% and 53% for clients ofsauna centers and 30% and 40% for clients of beauty parlors,respectively. The choice to use a condom was influenced byclients 60.8% of the time, sex workers 30.4%, and otherfactors 8.8 %. The choice against using a condom was decidedupon by clients 69.7% of the time, sex workers 9.1%, andother factors 21.2%. Multivariate analysis showed thateducational level and perception of risk of infection werefactors for condom use. Clients with a high school educationhad a higher condom use rate than those with a middle schooleducation or less. Furthermore, clients who perceived risk ofdisease used condoms more frequently than those who did ***: Clients played a significant role in decidingwhether or not to use a condom during commercial sex. Lackof perception of risk is a major factor for not using condoms.A program for promotion of prophylactics targeting bothcommercial sex workers and their clients is recommended.
Because resources to fund HIV prevention are limited, public health decision makers - such as health departments and HIV prevention community planning groups - need to know which prevention strategies are the most cos...
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Because resources to fund HIV prevention are limited, public health decision makers - such as health departments and HIV prevention community planning groups - need to know which prevention strategies are the most cost-effective. In the past several years, a number of studies have appeared in the literature that assess the cost-effectiveness of interventions to prevent the sexual transmission of HIV in the United States. Here, we comprehensively review 16 such studies and then outline an agenda for further research to advance the cost-effectiveness literature and to make the findings of these studies more useful for public health decision makers. The research summarized here provides compelling evidence that interventions to prevent sexual transmission of HIV can be highly cost-effective. Small-group, community-level, and outreach-based sexual risk reduction interventions, in particular, appear to be very efficient strategies for preventing the spread of HIV in moderate- to high-risk populations.
作者:
Weidle, Paul J.Epidemiology Branch
Division of HIV/AIDS Prevention National Center for HIV STD & TB Prevention Centers for Disease Control and Prevention 1600 Clifton Road MS E-45 Atlanta GA 30333
In this paper we review the cost-effectiveness of HIV counseling and testing in various settings and populations in preventing the sexual transmission of human immunodeficiency virus, and we discuss how multiple and c...
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In this paper we review the cost-effectiveness of HIV counseling and testing in various settings and populations in preventing the sexual transmission of human immunodeficiency virus, and we discuss how multiple and changing goals have influenced economic evaluations of these programs. The literature indicates that these interventions are generally cost-effective if targeted to groups of infected or high-risk individuals, although there is continuing debate over the efficacy of HIV counseling and testing in changing sexual behavior. For these reasons, HIV counseling and testing programs should be part of an overall prevention strategy which also includes more intensive sexual risk-reduction interventions such as individual, small-group, and community-level approaches.
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