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检索条件"机构=Center for Computational Systems Biology and Electrical and Computer Engineering"
583 条 记 录,以下是1-10 订阅
排序:
Dimensionality and dynamics for next-generation artificial neural networks
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Patterns 2025年
作者: Wang, Ge Fan, Feng-Lei Department of Biomedical Engineering Department of Electrical Computer and Systems Engineering Department of Computer Science Center for Computational Innovations Biomedical Imaging Center Center for Biotechnology and Interdisciplinary Studies Rensselaer Polytechnic Institute TroyNY United States Department of Data Science City University of Hong Kong Kowloon Hong Kong
The recent awarding of the Nobel Prize in Physics to Geoffrey E. Hinton and John J. Hopfield highlights their profound impact on artificial neural networks. In this perspective, we explore how their foundational insig... 详细信息
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Molecular architecture of mammalian pyruvate dehydrogenase complex
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Protein & Cell 2025年 第1期16卷 72-78页
作者: Maofei Chen Yutong Song Sensen Zhang Yitang Zhang Xudong Chen Minghui Zhang Meng Han Xin Gao Sai Li Maojun Yang Tsinghua-Peking Center for Life Sciences Beijing Frontier Research Center for Biological StructureSchool of Life SciencesTsinghua UniversityBeijing 100084China Ministry of Education Key Laboratory of Protein Science Tsinghua UniversityBeijing 100084China State Key Laboratory of Membrane Biology Tsinghua UniversityBeijing 100084China Department of Biochemistry and Molecular Biology School of Basic Medical SciencesShenzhen University Health Science CenterShenzhen 518060China Protein Research Technology Center Protein Chemistry and Omics PlatformSchool of Life SciencesTsinghua UniversityBeijing 100084China Computer Science Program ComputerElectrical and Mathematical Sciences and Engineering DivisionKing Abdullah University of Science and Technology(KAUST)Thuwal 23955-6900Kingdom of Saudi Arabia Computational Bioscience Research Center King Abdullah University of Science and TechnologyThuwal 23955-6900Kingdom of Saudi Arabia Cryo-EM Facility Center Southern University of Science and TechnologyShenzhen 518055China Beijing Life Science Academy Beijing 102209China
Dear Editor,Pyruvate dehydrogenase complex(PDHc) is a large multienzyme assembly(Mr = 4–10 million Daltons) consisting of three essential components: pyruvate dehydrogenase(E1p), dihydrolipoyl transacetylase(E2p), an... 详细信息
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Metallic and ferromagnetic carbon allotrope discovered using molecular precursors
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Physical Review Research 2025年 第1期7卷 013048-013048页
作者: Hong Fang Joel Therrien Puru Jena Department of Physics Rutgers University-Camden 530 Federal Street Camden New Jersey 08102 USA Center for Computational and Integrative Biology Rutgers University Camden New Jersey 08103 USA Department of Materials Science and Engineering Rutgers University-New Brunswick Piscataway New Jersey 08854 USA Department of Electrical and Computer Engineering University of Massachusetts Lowell Massachusetts 01854 USA Department of Physiscs Virginia Commonwealth University Richmond Virginia 23284 USA
Although carbon materials are known for their versatile structures and properties, a crystalline phase of carbon being both metallic and ferromagnetic is yet to be found. Here, using an organic molecular precursor 3,3... 详细信息
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Anisotropic exchange spin model to investigate the Curie temperature dispersion of L10-FePt magnetic nanoparticles
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Journal of Applied Physics 2025年 第18期137卷
作者: Ochiai, Kohei Tsuyama, Tomoyuki Shimizu, Sumera Zhang, Lei Watanabe, Jin Kudo, Fumito Zhu, Jian-Gang Okuno, Yoshishige Resonac Corporation Research Center for Computational Science and Informatics 8 Ebisu-cho Kanagawa-ku Kanagawa Yokohama221-8517 Japan Resonac Hard Disk Corporation Research & Development Center 5-1 Yawatakaigan-dori Chiba Ichihara290-0067 Japan Data Storage Systems Center Carnegie Mellon University PittsburghPA15213 United States Electrical and Computer Engineering Department Carnegie Mellon University PittsburghPA15213 United States Materials Science and Engineering Department Carnegie Mellon University PittsburghPA15213 United States
We developed an anisotropic exchange spin model that accounts for magnetic anisotropy and evaluated the Curie temperature ( T c ) dispersion due to finite-size effects in L1 0 -FePt nanoparticles. In heat-assisted mag... 详细信息
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Reconstructing Noisy Gene Regulation Dynamics Using Extrinsic-Noise-Driven Neural Stochastic Differential Equations
arXiv
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arXiv 2025年
作者: Zhang, Jiancheng Li, Xiangting Guo, Xiaolu You, Zhaoyi Böttcher, Lucas Mogilner, Alex Hoffmann, Alexander Chou, Tom Xia, Mingtao Department of Electrical and Computer Engineering University of California RiversideCA United States Department of Computational Medicine University of California Los AngelesCA United States Institute for Quantitative and Computational Biosciences University of California Los Angeles Los AngelesCA United States Ray and Stephanie Lane Computational Biology Department School of Computer Science Carnegie Mellon University PittsburghPA United States Department of Computational Science and Philosophy Frankfurt School of Finance and Management Frankfurt am Main Germany Laboratory for Systems Medicine Department of Medicine University of Florida FL32610 United States Courant Institute of Mathematical Sciences New York University NY10012 United States Department of Mathematics University of California Los AngelesCA90095 United States Department of Mathematics University of Houston HoustonTX77004 United States
Proper regulation of cell signaling and gene expression is crucial for maintaining cellular function, development, and adaptation to environmental changes. Reaction dynamics in cell populations is often noisy because ... 详细信息
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Anisotropic Exchange Spin Model to Investigate the Curie Temperature Dispersion of Finite-Size L10-FePt Magnetic Nanoparticles
arXiv
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arXiv 2025年
作者: Ochiai, Kohei Tsuyama, Tomoyuki Shimizu, Sumera Zhang, Lei Watanabe, Jin Kudo, Fumito Zhu, Jian-Gang Okuno, Yoshishige Resonac Corporation Research Center for Computational Science and Informatics 8 Ebisu-cho Kanagawa-ku Kanagawa. Yokohama221-8517 Japan Resonac Hard Disk Corporation Research & Development Center 5-1 Yawatakaigan-dori Chiba Ichihara290-0067 Japan Data Storage Systems Center Carnegie Mellon University PittsburghPA15213 United States Electrical and Computer Engineering Department Carnegie Mellon University PittsburghPA15213 United States Materials Science and Engineering Department Carnegie Mellon University PittsburghPA15213 United States
We developed an anisotropic spin model that accounts for magnetic anisotropy and evaluated the Curie temperature (Tc) dispersion due to finite size effects in L10-FePt nanoparticles. In heat-assisted magnetic recordin... 详细信息
来源: 评论
Biomedical data and AI
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Science China Life Sciences 2025年 第5期68卷 1536-1540页
作者: Hao Xu Shibo Zhou Zefeng Zhu Vincenzo Vitelli Liangyi Chen Ziwei Dai Ning Yang Luhua Lai Shengyong Yang Sergey Ovchinnikov Zhuoran Qiao Sirui Liu Chen Song Jianfeng Pei Han Wen Jianfeng Feng Yaoyao Zhang Zhengwei Xie Yang-Yu Liu Zhiyuan Li Fulai Jin Hao Li Mohammad Lotfollahi Xuegong Zhang Ge Yang Shihua Zhang Ge Gao Pulin Li Qi Liu Jing-Dong Jackie Han Peking-Tsinghua Center for Life Sciences (CLS) Academy for Advanced Interdisciplinary StudiesPeking University Center for Quantitative Biology (CQB) Academy for Advanced Interdisciplinary StudiesPeking University Peking University-Tsinghua University-National Institute of Biological Sciences Joint Graduate Program Academy for Advanced Interdisciplinary StudiesPeking University Department of Physics University of Chicago School of Life Sciences Southern University of Science and Technology Peking University Chengdu Academy for Advanced Interdisciplinary Biotechnologies College of Chemistry and Molecular Engineering Peking University Department of Biotherapy Cancer Center and State Key Laboratory of BiotherapyWest China HospitalSichuan University Department of Biology Massachusetts Institute of Technology Lambic Therapeutics Inc. Changping Laboratory Al for Science Institute Key Laboratory of Computational Neuroscience and Brain-Inspired Intelligence Fudan University Department of Obstetrics and Gynecology West China Second University HospitalSichuan University Peking University International Cancer Institute and Peking University-Yunnan Baiyao International Medical Institute and State Key Laboratory of Natural and Biomimetic Drugs Department of Molecular and Cellular PharmacologySchool of Pharmaceutical SciencesPeking University Health Science CenterPeking University Channing Division of Network Medicine Department of MedicineBrigham and Women's Hospital and Harvard Medical School Center for Artificial Intelligence and Modeling the Carl R.Woese Institute for Genomic BiologyUniversity of Illinois Urbana-Champaign Department of Genetics and Genome Sciences School of Medicine and Department of Computer and Data Sciences and Department of Population and Quantitative Health SciencesCase Western Reserve University Department of Biochemistry and Biophysics University of California Sanger Institute Department of Automation Tsinghua University State Key Laboratory of Multimodal Artificial Intelligence Systems I
The development of artificial intelligence(AI) and the mining of biomedical data complement each other. From the direct use of computer vision results to analyze medical images for disease screening, to now integratin...
来源: 评论
MedMimic: A Physician-Inspired Multimodal Fusion Framework for Early Diagnosing Fever of Unknown Origin
arXiv
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arXiv 2025年
作者: Chen, Minrui Zhou, Yi Jiang, Huidong Zhu, Yuhan Zou, Guanjie Chen, Minqi Tian, Rong Saigo, Hiroto Department of Information Science and Technology Kyushu University Fukuoka Japan Department of Nuclear Medicine West China Hospital Sichuan University Chengdu China Department of Computer Science Institute of Science Tokyo Yokohama Japan Center for Advanced Intelligence Project RIKEN Tokyo Japan Department of Computational Biology and Medical Sciences University of Tokyo Tokyo Japan Department of Thoracic Surgery Institute of Thoracic Oncology West China Hospital Sichuan University Chengdu China Department of Electrical Engineering and Computer Science Kyushu University Fukuoka Japan
Fever of unknown origin (FUO) poses a significant diagnostic challenge, often requiring extensive evaluations. While recent efforts integrating clinical features with 18F-FDG PET/CT imaging have improved diagnostic ac... 详细信息
来源: 评论
Boosting multi-demographic federated learning for chest x-ray analysis using general-purpose self-supervised representations
arXiv
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arXiv 2025年
作者: Lotfinia, Mahshad Tayebiarasteh, Arash Samiei, Samaneh Joodaki, Mehdi Arasteh, Soroosh Tayebi Department of Diagnostic and Interventional Radiology University Hospital RWTH Aachen Aachen Germany Department of Computer Engineering Hamedan University of Technology Hamedan Iran Quantitative Cell Dynamics and Translational Systems Biology University Hospital RWTH Aachen Aachen Germany Institute for Computational Genomics Joint Research Center for Computational Biomedicine University Hospital RWTH Aachen Aachen Germany Pattern Recognition Lab Friedrich-Alexander-Universität Erlangen-Nürnberg Erlangen Germany Department of Urology Stanford University StanfordCA United States Department of Radiology Stanford University StanfordCA United States
Reliable artificial intelligence (AI) models for medical image analysis often depend on large and diverse labeled datasets. Federated learning (FL) offers a decentralized and privacy-preserving approach to training bu... 详细信息
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Tree Reconstruction Guarantees from CRISPR-Cas9 Lineage Tracing Data Using Neighbor-Joining  29th
Tree Reconstruction Guarantees from CRISPR-Cas9 Lineage Tra...
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29th International Conference on Research in computational Molecular biology, RECOMB 2025
作者: Prillo, Sebastian An, Kevin Wu, Wilson Kristanto, Ivan Jones, Matthew G. Song, Yun S. Yosef, Nir Department of Electrical Engineering and Computer Sciences University of California Berkeley BerkeleyCA94720 United States Department of Systems Immunology Weizmann Institute of Science Rehovot7610001 Israel Department of Statistics University of California Berkeley BerkeleyCA94720 United States Department of Molecular and Cell Biology University of California Berkeley BerkeleyCA94720 United States Center for Personal Dynamic Regulomes Stanford University StanfordCA94305 United States
CRISPR-Cas9 based lineage tracing technologies have enabled the reconstruction of single-cell phylogenies from transcriptional readouts. However, developing tree-reconstruction algorithms with theoretical guarantees i...
来源: 评论