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检索条件"机构=Center for Computational Systems Biology and Electrical and Computer Engineering"
583 条 记 录,以下是1-10 订阅
排序:
Controlling Biomolecular Timekeeping via Regulated Gene Product Degradation  63
Controlling Biomolecular Timekeeping via Regulated Gene Prod...
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63rd IEEE Conference on Decision and Control, CDC 2024
作者: Rezaee, Sayeh Nieto, Cesar Singh, Abhyudai University of Delaware Department of Electrical and Computer Engineering NewarkDE United States University of Delaware Biomedical Engineering Mathematical Sciences Center of Bioinformatic and Computational Biology Department of Electrical and Computer Engineering NewarkDE United States
Numerous biological timing mechanisms are associated with the duration required for key regulatory molecules to reach critical threshold levels. Recent studies have mainly explored how random fluctuations affect the t... 详细信息
来源: 评论
Feedforward Regulation of Interneuronal Communication  63
Feedforward Regulation of Interneuronal Communication
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63rd IEEE Conference on Decision and Control, CDC 2024
作者: Gambrell, Oliver Vahdat, Zahra Singh, Abhyudai University of Delaware Department of Electrical and Computer Engineering NewarkDE19716 United States University of Delaware Biomedical Engineering Mathematical Sciences Center for Bioinformatics and Computational Biology Department of Electrical and Computer Engineering NewarkDE19716 United States
We formulate a mechanistic model capturing the dynamics of neurotransmitter release in a chemical synapse. The proposed modeling framework captures key aspects such as the random arrival of action potentials (AP) in t... 详细信息
来源: 评论
Quantifying statistics of gene product copy-number fluctuations: A stochastic hybrid systems approach  63
Quantifying statistics of gene product copy-number fluctuati...
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63rd IEEE Conference on Decision and Control, CDC 2024
作者: Vahdat, Zahra Singh, Abhyudai University of Delaware Department of Electrical and Computer Engineering NewarkDE19716 United States University of Delaware Department of Electrical and Computer Engineering Biomedical Engineering Mathematical Sciences Center for Bioinformatics and Computational Biology NewarkDE19716 United States
Across diverse cell types, genes are often expressed at low levels resulting in significant stochastic fluctuations (noise) in intracellular copy number of mRNAs and proteins over time. Motivated by single-cell experi... 详细信息
来源: 评论
Stochastic dynamics of the logistic growth model subjected to environmental perturbations
Stochastic dynamics of the logistic growth model subjected t...
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2023 IEEE Conference on Control Technology and Applications, CCTA 2023
作者: Rezaee, Sayeh Nieto, Cesar Vahdat, Zahra Singh, Abhyudai University of Delaware Department of Electrical and Computer Engineering NewarkDE United States University of Delaware Biomedical Engineering Mathematical Sciences Center of Bioinformatic and Computational Biology Department of Electrical and Computer Engineering NewarkDE United States
The stochastic logistic model is widely used to capture random fluctuations arising from birth-death processes in ecological populations. We use this model to study the impact of environmental perturbations that may o... 详细信息
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Optimizing Precision in Cellular Clocks Through Self-Regulated Accumulation Of Molecules  27
Optimizing Precision in Cellular Clocks Through Self-Regulat...
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27th International Conference on System Theory, Control and Computing, ICSTCC 2023
作者: Rezaee, Sayeh Nieto, César Singh, Abhyudai Department of Electrical and Computer Engineering University of Delaware NewarkDE United States Department of Electrical and Computer Engineering Biomedical Engineering Mathematical Sciences Center of Bioinformatic and Computational Biology University of Delaware NewarkDE United States
The timing of cellular events is often determined by the instant when the level of a chemical species crosses a threshold from an initial value of zero. To attenuate the inherent random fluctuations in this first-pass... 详细信息
来源: 评论
A Multi-phase Deep Learning Approach for Predicting HCC Response to TACE using Complete Computed Tomography
A Multi-phase Deep Learning Approach for Predicting HCC Resp...
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2023 IEEE EMBS Special Topic Conference on Data Science and engineering in Healthcare, Medicine and biology, IEEECONF 2023
作者: Chang, Shun Cheng Liu, Chien Fu Misztal, Marta Hsieh, Yi Hsien Lin, Che Taiwan School of Electronic Engineering and Computer Science Queen Mary University of London United Kingdom Department of Electrical Engineering Ntu Taiwan Center for Computational and Systems Biology Center for Biotechnology Ntu Taiwan Smart Medicine and Health Informatics Program Ntu Taiwan
In this research study, we compare the predictive performance of two advanced deep learning-based models in order to provide a solution to TACE (Transarterial Chemoembolization) response prediction in HCC (Hepatocellu... 详细信息
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Inferring the Effects of Protein Variants on Protein-Protein Interactions with Interpretable Transformer Representations
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Research 2024年 第2期2023卷 473-489页
作者: Zhe Liu Wei Qian Wenxiang Cai Weichen Song Weidi Wang Dhruba Tara Maharjan Wenhong Cheng Jue Chen Han Wang Dong Xu Guan Ning Lin Shanghai Mental Health Center Shanghai Jiao Tong University School of MedicineSchool of Biomedical EngineeringShanghai Jiao Tong UniversityShanghaiChina Shanghai Key Laboratory of Psychotic Disorders ShanghaiChina School of Information Science and Technology Institute of Computational BiologyNortheast Normal UniversityChangchunChina Department of Electrical Engineering and Computer Science University of MissouriColumbiaMO 65211USA Christopher S.Bond Life Sciences Center University of MissouriColumbiaMO 65211USA
Identifying pathogenetic variants and inferring their impact on protein-protein interactions sheds light on their functional consequences on *** by the availability of experimental data on the consequences of protein ... 详细信息
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Capturing non-Gaussian statistics in noise-injection driven dynamical systems
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IFAC-PapersOnLine 2024年 57卷 250-255页
作者: Zahra Vahdat Cesar Nieto Abhyudai Singh Department of Electrical and Computer Engineering University of Delaware Newark DE USA 19716 Department of Electrical and Computer Engineering Department of Biomedical Engineering Mathematical Sciences Center for Bioinformatics and Computational Biology University of Delaware Newark DE USA 19716
The canonical approach to modeling stochasticity considers a dynamical system driven by Gaussian white noise. Here, we propose an alternative hybrid formulation, in which continuous dynamics is interspersed with noise... 详细信息
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Capturing statistical fluctuations in gene expression activity using discrete stochastic systems
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IFAC-PapersOnLine 2024年 第1期58卷 276-281页
作者: Zahra Vahdat Sayeh Rezaee Abhyudai Singh Department of Electrical and Computer Engineering University of Delaware Newark DE USA 19716 Department of Electrical and Computer Engineering Department of Biomedical Engineering Mathematical Sciences Center for Bioinformatics and Computational Biology University of Delaware Newark DE USA 19716
We present a discrete-event system formalism to capture experimentally observed activity of genes in single cells, where a gene can stochastically switch between an active state (synthesis of gene products, such as mR... 详细信息
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A Framework of Deep Optimal Features Selection for Apple Leaf Diseases Recognition
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computers, Materials & Continua 2023年 第4期75卷 697-714页
作者: Samra Rehman Muhammad Attique Khan Majed Alhaisoni Ammar Armghan Usman Tariq Fayadh Alenezi Ye Jin Kim Byoungchol Chang Department of Computer Science HITEC UniversityTaxilaPakistan Computer Sciences Department College of Computer and Information SciencesPrincess Nourah bint Abdulrahman UniversityRiyadh11671Saudi Arabia Department of Electrical Engineering College of EngineeringJouf UniversitySakakahSaudi Arabia Department of Management Information Systems CoBAPrince Sattam bin Abdulaziz UniversitySaudi Arabia Department of Computer Science Hanyang UniversitySeoul04763Korea Center for Computational Social Science Hanyang UniversitySeoul04763Korea
Identifying fruit disease manually is time-consuming, expertrequired,and expensive;thus, a computer-based automated system is widelyrequired. Fruit diseases affect not only the quality but also the *** a result, it is... 详细信息
来源: 评论