Small lesions play a critical role in early disease diagnosis and intervention of severe infections. Popular models often face challenges in segmenting small lesions, as it occupies only a minor portion of an image, w...
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The discovery and identification of molecules in biological and environmental samples is crucial for advancing biomedical and chemical sciences. Tandem mass spectrometry (MS/MS) is the leading technique for high-throu...
ISBN:
(纸本)9798331314385
The discovery and identification of molecules in biological and environmental samples is crucial for advancing biomedical and chemical sciences. Tandem mass spectrometry (MS/MS) is the leading technique for high-throughput elucidation of molecular structures. However, decoding a molecular structure from its mass spectrum is exceptionally challenging, even when performed by human experts. As a result, the vast majority of acquired MS/MS spectra remain uninterpreted, thereby limiting our understanding of the underlying (bio)chemical processes. Despite decades of progress in machine learning applications for predicting molecular structures from MS/MS spectra, the development of new methods is severely hindered by the lack of standard datasets and evaluation protocols. To address this problem, we propose MassSpecGym - the first comprehensive benchmark for the discovery and identification of molecules from MS/MS data. Our benchmark comprises the largest publicly available collection of high-quality labeled MS/MS spectra and defines three MS/MS annotation challenges: de novo molecular structure generation, molecule retrieval, and spectrum simulation. It includes new evaluation metrics and a generalization-demanding data split, therefore standardizing the MS/MS annotation tasks and rendering the problem accessible to the broad machine learning community. MassSpecGym is publicly available at https://***/pluskal-lab/MassSpecGym.
In order to devise an anomaly detection model using only normal training data, an autoencoder (AE) is typically trained to reconstruct the data. As a result, the AE can extract normal representations in its latent spa...
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Video-based action recognition is becoming a vital tool in clinical research and neuroscientific study for disorder detection and ***,action recognition currently used in non-human primate(NHP)research relies heavily ...
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Video-based action recognition is becoming a vital tool in clinical research and neuroscientific study for disorder detection and ***,action recognition currently used in non-human primate(NHP)research relies heavily on intense manual labor and lacks standardized *** this work,we established two standard benchmark datasets of NHPs in the laboratory:Monkeyin Lab(Mi L),which includes 13 categories of actions and postures,and MiL2D,which includes sequences of two-dimensional(2D)skeleton ***,based on recent methodological advances in deep learning and skeleton visualization,we introduced the Monkey Monitor Kit(Mon Kit)toolbox for automatic action recognition,posture estimation,and identification of fine motor activity in *** the datasets and Mon Kit,we evaluated the daily behaviors of wild-type cynomolgus monkeys within their home cages and experimental environments and compared these observations with the behaviors exhibited by cynomolgus monkeys possessing mutations in the MECP2 gene as a disease model of Rett syndrome(RTT).Mon Kit was used to assess motor function,stereotyped behaviors,and depressive phenotypes,with the outcomes compared with human manual *** Kit established consistent criteria for identifying behavior in NHPs with high accuracy and efficiency,thus providing a novel and comprehensive tool for assessing phenotypic behavior in monkeys.
Over the years, Machine Learning models have been successfully employed on neuroimaging data for accurately predicting brain age. Deviations from the healthy brain aging pattern are associated with the accelerated bra...
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The term "Cyber Security" is getting more and more popular and important over the last few years. Since computers and most of the devices are connected to the internet, they are likely to be hacked by the ha...
The term "Cyber Security" is getting more and more popular and important over the last few years. Since computers and most of the devices are connected to the internet, they are likely to be hacked by the hackers. In the past, this issue was not a big problem, because not every device is required to be connected to the internet or the internet was not popular as today. But the case has changed over the years. All the changes in the technology area also changed the cyber-attack models as well. With the development of technology and the change of usage of the internet over the last years cyber-attacks have become more common and popular by the hackers. Hackers have discovered that they have an opportunity to steal or earn money in a short time without having to spend too much effort. These days, the type of cyber-attacks is not the same as the ones in the past. As time passes, the cyber-attack methods are also changing and evolving. Today, hackers are using more advanced and effective cyber-attack methods compared to past years. There are many methods that are impossible to cover all of them in this article. Our main focus will be on social engineering attacks in this article. Social engineering attacks use different approaches to cyber attacking. Unlike trying to explode a victim’s social media password etc. using advanced exporting programs, algorithms or techniques, social engineering attacks focus on fooling victims into providing their data to hackers by themselves without using or implementing any password cracking, exploiting techniques etc. We will go over what social media engineering is, type of social engineering methods, what countermeasures can be used to protect from social engineering and more in this article.
Combination of multi-modal PET-CT imaging for lung tumor segmentation is significant for clinical treatment. Existing methods have not fully considered the impact of noise in PET-CT on the multi-modal interaction. To ...
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ISBN:
(数字)9798350390155
ISBN:
(纸本)9798350390162
Combination of multi-modal PET-CT imaging for lung tumor segmentation is significant for clinical treatment. Existing methods have not fully considered the impact of noise in PET-CT on the multi-modal interaction. To address this, we propose a novel Attention in Attention Network (AiANet). AiANet can mutually learn multi-modal characteristics for segmentation through its cross-learning modules. Within the cross-learning module, we introduce two nested-attention blocks, namely Attention in Self-Attention (AiSA) and Attention in Cross-Attention (AiCA), for multi-scale feature enhancement and multi-modal feature interaction. Importantly, since traditional attention weights calculated solely or unilaterally based on PET or CT can be vulnerable to the inevitable noisy information, we embed a novel Attention in Attention (AiA) module into AiSA and AiCA. The AiA module can seek cross-modal consensus for attention weights to alleviate their noise. Experimental results on clinical PET-CT data of lung cancer demonstrate the superiority of our method.
Cross-View Geo-Localization (CVGL) estimates the location of a ground image by matching it to a geo-tagged aerial image in a database. Recent works achieve outstanding progress on CVGL benchmarks. However, existing me...
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The evolution of healthcare systems worldwide necessitates continual improvement in hospital management practices, particularly pharmaceutical management. This paper explores transforming traditional pharmaceutical ma...
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Neural networks excel at capturing local spatial patterns through convolutional modules,but they may struggle to identify and effectively utilize the morphological and amplitude periodic nature of physiological *** th...
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Neural networks excel at capturing local spatial patterns through convolutional modules,but they may struggle to identify and effectively utilize the morphological and amplitude periodic nature of physiological *** this work,we propose a novel network named filtering module fully convolutional network(FM-FCN),which fuses traditional filtering techniques with neural networks to amplify physiological signals and suppress ***,instead of using a fully connected layer,we use an FCN to preserve the time-dimensional correlation information of physiological signals,enabling multiple cycles of signals in the network and providing a basis for signal ***,we introduce the FM as a network module that adapts to eliminate unwanted interference,leveraging the structure of the *** approach builds a bridge between deep learning and signal processing ***,we evaluate the performance of FM-FCN using remote *** results demonstrate that FM-FCN outperforms the second-ranked method in terms of both blood volume pulse(BVP)signal and heart rate(HR)*** substantially improves the quality of BVP waveform reconstruction,with a decrease of 20.23%in mean absolute error(MAE)and an increase of 79.95%in signal-to-noise ratio(SNR).Regarding HR estimation accuracy,FM-FCN achieves a decrease of 35.85%in MAE,29.65%in error standard deviation,and 32.88%decrease in 95%limits of agreement width,meeting clinical standards for HR accuracy *** results highlight its potential in improving the accuracy and reliability of vital sign measurement through high-quality BVP signal *** codes and datasets are available online at https://***/zhaoqi106/FM-FCN.
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