检索结果-内蒙古大学图书馆

The impact of hot nights on dengue incidence: a nationwide case crossover study in Brazil

学校读者我要写书评

暂无评论

Infectious diseases of poverty 2025年第1期14卷 50页

作者： Mintao Su Junjun Chen Zhisheng Liang Qinfeng Zhou Junxiong Ma Huining Yang Shaym Biswal Murugappan Ramanathan Haojun Fan Fan Dai Wei Huang Minghui Ren Zhenyu Zhang Department of Global Health Peking University School of Public Health 38 Xue Yuan Road Haidian District Beijing 100191 China. Department of Electrical and Computer Engineering Johns Hopkins University Baltimore USA. Department of Disease Prevention and Control Third Medical Center of General Hospital of the People's Liberation Army Beijing China. Bloomberg School of Public Health Johns Hopkins University Baltimore USA. School of Medicine Johns Hopkins University Baltimore USA. Institute of Disaster and Emergency Medicine Tianjin University Tianjin China. California-China Climate Institute University of California Berkeley School of Law Berkeley CA USA. Institute of Environmental Medicine Peking University School of Public Health Beijing 100191 China. China Center for Health Development Studies Peking University Beijing China. Department of Global Health Peking University School of Public Health 38 Xue Yuan Road Haidian District Beijing 100191 China. zzy@***. Institute for Global Health and Development Peking University Beijing China. zzy@***. Institute of Carbon Neutrality Peking University Beijing China. zzy@***.

BACKGROUND:Dengue fever, a mosquito-borne disease, is influenced by temperature. As global warming intensifies, the frequency of hot nights has increased. However, the relationship between hot nights and dengue transmission remains unclear. This study aimed to evaluate the impact of hot night exposures on dengue incidence. METHODS:We collected individual dengue data from Brazil's SINAN database (2014-2021), covering 5,708,691 patients. Hot night exposures, including the average maximum nighttime temperatures, hot night excess, and hot night duration, were calculated using the ERA5-land dataset. A case-crossover design was employed to assess the association between each hot night exposure and dengue incidence using conditional logistic regression. RESULTS:The average maximum nighttime temperature, hot night excess, and hot night duration were all significantly associated with increased risk of dengue, with odds ratios (ORs) of 1.86 (95% CI 1.86-1.87), 1.01 (95% CI 1.01-1.01), and 1.05 (95% CI 1.05-1.05), respectively. The attributable risks for each hot night exposure were 14.02% (95% CI 13.49%-14.60%), 27.80% (95% CI 27.33%-28.21%), and 26.95% (95% CI 26.58%-27.38%), respectively, when the exposure value was above the 90th percentile of its distribution. CONCLUSIONS:Hot night exposures were associated with an increased risk of dengue in Brazil. The public health burden of dengue is likely to rise with increasing hot night exposures, especially as hot nights become more frequent worldwide. Implementation of targeted vector control strategies and improved access to cooling equipment, such as air-conditioning, may serve as important mitigation measures.

关键词： Attributable risk Brazil Dengue Hot nights Temperature

Neuroprotective effects of Ginkgo biloba extract and GinkgoUde B against oxygen-glucose deprivation/reoxygenation and glucose injury in a new in vitro multicellular network model

学校读者我要写书评

暂无评论

Frontiers of Medicine 2018年第3期12卷 307-318页

作者： Xiaohan Yang Tiezheng Zheng Hao Hong Nan Cai Xiaofeng Zhou Changkai Sun Liying Wu Shuhong Liu Yongqi Zhao Lingling Zhu Ming Fan Xuezhong Zhou Fengxie Jin Department of Biomedical Engineering Faculty of Electronic Information and Electrical Engineering Dalian University of Technology Dalian 116024 China Research Center for the Control Engineering of Translational Precision Medicine Dalian University of Technology Dalian 116024 China State Key Laboratory of Fine Chemicals Dalian R&D Center for Stem Cell and Tissue Engineering Dalian University of Technology Dalian 116024 China Liaoning Provincial Key Laboratory of Cerebral Diseases Institute for Brain Disorders Dalian Medical University Dalian 116044 China Institute of Basic Medical Sciences Academy of Military Medical Sciences Beijing 100850 China School of Computer and Information Technology and Beijing Key Lab of Traffic Data Analysis and Mining Beijing Jiaotong University Beijing 100044 China College of Biotecknology Dalian Polytechnic University Dalian 116034 China

Acute ischemic stroke （AIS）, as the third leading cause of death worldwide, is characterized by its high incidence, mortality rate, high incurred disability rate, and frequent reoccurrence. The neuroprotective effects of Ginkgo biloba extract （GBE） against several cerebral diseases have been reported in previous studies, but the underlying mechanisms of action are still unclear. Using a novel in vitro rat cortical capillary endothelial cell- astrocyte-neuron network model, we investigated the neuroprotective effects of GBE and one of its important constituents, Ginkgolide B （GB）, against oxygenglucose deprivation/reoxygenation and glucose （OGD/R） injury. In this model, rat cortical capillary endothelial cells, astrocytes, and neurons were cocultured so that they could be synchronously observed in the same system. Pretreatment with GBE or GB increased the neuron cell viability, ameliorated cell injury, and inhibited the cell apoptotic rate through Bax and Bcl-2 expression regulation after OGD/R injury. Furthermore, GBE or GB pretreatment enhanced the transendothelial electrical resistance of capillary endothelial monolayers, reduced the endothelial permeability coefficients for sodium fluorescein （Na-F）, and increased the expression levels of tight junction proteins, namely, ZO-1 and occludin, in endothelial cells. Results demonstrated the preventive effects of GBE on neuronal cell death and enhancement of the function of brain capillary endothelial monolayers after OGD/R injury in vitro; thus, GBE could be used as an effective neuroprotective agent for AIS/reperfusion, with GB as one of its significant constituents.

关键词： acute ischemic stroke Ginkgo biloba extract Ginkgolide B network model neuroprotection

Second-order coding rates for key distillation in quantum key distribution

学校读者我要写书评

暂无评论

arXiv 2019年

作者： Khatri, Sumeet Kaur, Eneet Guha, Saikat Wilde, Mark M. Hearne Institute for Theoretical Physics Department of Physics and Astronomy Center for Computation and Technology Louisiana State University Baton RougeLA70803 United States College of Optical Sciences University of Arizona 1630 E. University Blvd. TucsonAZ85719 United States Department of Electrical and Computer Engineering University of Arizona 1230 E Speedway Blvd. TucsonAZ85719 United States

The security of quantum key distribution has traditionally been analyzed in either the asymptotic or non-asymptotic regimes. In this paper, we provide a bridge between these two regimes, by determining second-order coding rates for key distillation in quantum key distribution under collective attacks. Our main result is a formula that characterizes the backoff from the known asymptotic formula for key distillation-our formula incorporates the reliability and security of the protocol, as well as the mutual information variances to the legitimate receiver and the eavesdropper. In order to determine secure key rates against collective attacks, one should perform a joint optimization of the Holevo information and the Holevo information variance to the eavesdropper. We show how to do so by analyzing several examples, including the six-state, BB84, and continuous-variable quantum key distribution protocols (the last involving Gaussian modulation of coherent states along with heterodyne detection). The technical contributions of this paper include one-shot and second-order analyses of private communication over a compound quantum wiretap channel with fixed marginal and key distillation over a compound quantum wiretap source with fixed marginal. We also establish the second-order asymptotics of the smooth max-relative entropy of quantum states acting on a separable Hilbert space, and we derive a formula for the Holevo information variance of a Gaussian ensemble of Gaussian states. Copyright © 2019, The Authors. All rights reserved.

关键词： Quantum cryptography

Topological nonlinear anomalous Nernst effect in strained transition metal dichalcogenides

学校读者我要写书评

暂无评论

Physical Review B 2019年第20期99卷 201410(R)-201410(R)页

作者： Xiao-Qin Yu Zhen-Gang Zhu Jhih-Shih You Tony Low Gang Su School of Physics and Electronics Hunan University Changsha 410082 China School of Electronic Electrical and Communication Engineering University of Chinese Academy of Sciences Beijing 100049 China Theoretical Condensed Matter Physics and Computational Materials Physics Laboratory College of Physical Sciences University of Chinese Academy of Sciences Beijing 100049 China CAS Center for Excellence in Topological Quantum Computation University of Chinese Academy of Sciences Beijing 100190 China Institute for Theoretical Solid State Physics IFW Dresden Helmholtzstraße 20 01069 Dresden Germany Department of Electrical and Computer Engineering University of Minnesota Minneapolis Minnesota 55455 USA Kavli Institute of Theoretical Sciences University of Chinese Academy of Sciences Beijing 100049 China

We theoretically analyze the nonlinear anomalous Nernst effect as the second-order response of temperature gradient by using the semiclassical framework of electron dynamics. We find that a nonlinear current can be generated transverse to the applied temperature gradient in time-reversal-symmetry materials with broken inversion symmetry. This effect has a quantum origin arising from the Berry curvature of states near the Fermi surface. We discuss the nonlinear Nernst effect in transition metal dichalcogenides (TMDCs) under the application of uniaxial strain. In particular, we predict that under fixed chemical potential in TMDCs, the nonlinear Nernst current exhibits a transition from T−2 temperature dependence in low temperature regime to a linear T dependence in high temperature.

关键词： Geometric & topological phases Nernst effect Thermal Hall effect Thermoelectric effects Topological materials Transition metal dichalcogenides Boltzmann theory

Experimental Demonstration of Quantum Fully Homomorphic Encryption with Application in a Two-Party Secure Protocol

学校读者我要写书评

暂无评论

Physical Review X 2020年第1期10卷 011038-011038页

作者： W. K. Tham Hugo Ferretti Kent Bonsma-Fisher Aharon Brodutch Barry C. Sanders Aephraim M. Steinberg Stacey Jeffery Department of Physics and Center for Quantum Information and Quantum Control University of Toronto 60 St. George Street Toronto Ontario M5S 1A7 Canada The Edward S. Rogers Department of Electrical and Computer Engineering University of Toronto 10 Kings College Road Toronto Ontario M5S 3G4 Canada Institute for Quantum Science and Technology University of Calgary Alberta T2N 1N4 Canada Institute for Quantum Information and Matter California Institute of Technology Pasadena California 91125 USA Canadian Institute for Advanced Research Toronto Ontario M5G 1M1 Canada QuSoft and CWI Amsterdam 1098 XG Netherlands

A fully homomorphic encryption system hides data from unauthorized parties while still allowing them to perform computations on the encrypted data. Aside from the straightforward benefit of allowing users to delegate computations to a more powerful server without revealing their inputs, a fully homomorphic cryptosystem can be used as a building block in the construction of a number of cryptographic functionalities. Designing such a scheme remained an open problem until 2009, decades after the idea was first conceived, and the past few years have seen the generalization of this functionality to the world of quantum machines. Quantum schemes prior to the one implemented here were able to replicate some features in particular use cases often associated with homomorphic encryption but lacked other crucial properties, for example, relying on continual interaction to perform a computation or leaking information about the encrypted data. We present the first experimental realization of a quantum fully homomorphic encryption scheme. To demonstrate the versatility of a a quantum fully homomorphic encryption scheme, we further present a toy two-party secure computation task enabled by our scheme.

关键词： Photon pairs & parametric down-conversion Quantum cryptography Quantum gates Quantum information with atoms & light

Robust control of the sit-to-stand movement for a powered lower limb orthosis

学校读者我要写书评

暂无评论

arXiv 2018年

作者： Narvaez-Aroche, Octavio Meyer, Pierre-Jean Tu, Stephen Packard, Andrew Arcak, Murat Berkeley Center for Control and Identification Department of Mechanical Engineering University of California BerkeleyCA94720 Department of Electrical Engineering and Computer Sciences University of California BerkeleyCA94720 United States

The sit-to-stand movement is a key feature for wide adoption of powered lower limb orthoses for patients with complete paraplegia. In this paper we study the control of the ascending phase of the sit-to-stand movement for a minimally actuated powered lower limb orthosis at the hips. First, we generate a pool of finite horizon Linear Quadratic Regulator feedback gains, designed under the assumption that we can control not only the torque at the hips but also the loads at the shoulders that in reality are applied by the user. Next we conduct reachability analysis to define a performance metric measuring the robustness of each controller against parameter uncertainty, and choose the best controller from the pool with respect to this metric. Then, we replace the presumed shoulder control with an Iterative Learning control algorithm as a substitute for human experiments. Indeed this algorithm obtains torque and forces at the shoulders that result in successful simulations of the sit-to-stand movement, regardless of parameter uncertainty and factors deliberately introduced to hinder learning. Thus it is reasonable to expect that the superior cognitive skills of real users will enable them to cooperate with the hip torque controller through training. Copyright © 2018, The Authors. All rights reserved.

关键词： Robust control

Finite time robust control of the sit-to-stand movement for powered lower limb orthoses

学校读者我要写书评

暂无评论

arXiv 2018年

作者： Narvaez-Aroche, Octavio Packard, Andrew Arcak, Murat Department of Mechanical Engineering Berkeley Center for Control and Identification University of California Berkeley United States Department of Electrical Engineering and Computer Sciences University of California BerkeleyCA94720 United States

This study presents a technique to safely control the Sit-to-Stand movement of powered lower limb orthoses in the presence of parameter uncertainty. The weight matrices used to calculate the finite time horizon linear-quadratic regulator (LQR) gain in the feedback loop are chosen from a pool of candidates as to minimize a robust performance metric involving induced gains that measure the deviation of variables of interest in a linear time-varying (LTV) system, at specific times within a finite horizon, caused by a perturbation signal modeling the variation of the parameters. Two relevant Sit-to-Stand movements are simulated for drawing comparisons with the results documented in a previous work. Copyright © 2018, The Authors. All rights reserved.

关键词： Orthotics

Reachability analysis for robustness evaluation of the sit-to-stand movement for powered lower limb orthoses

学校读者我要写书评

暂无评论

arXiv 2018年

作者： Narvaez-Aroche, Octavio Packard, Andrew Meyer, Pierre-Jean Arcak, Murat Berkeley Center for Control and Identification Department of Mechanical Engineering University of California Berkeley California94720 Department of Electrical Engineering and Computer Sciences University of California BerkeleyCA94720 United States

A sensitivity-based approach for computing over-approximations of reachable sets, in the presence of constant parameter uncertainties and a single initial state, is used to analyze a three-link planar robot modeling a Powered Lower Limb Orthosis and its user. Given the nature of the mappings relating the state and parameters of the system with the inputs, and outputs describing the trajectories of its center of Mass, reachable sets for their respective spaces can be obtained relying on the sensitivities of the nonlinear closed-loop dynamics in the state space. These over-approximations are used to evaluate the worst-case performances of a finite time horizon linear-quadratic regulator (LQR) for controlling the ascending phase of the Sit-To-Stand movement. Copyright © 2018, The Authors. All rights reserved.

关键词： Uncertainty analysis

Authors’ Response to Peer Reviews of “Emergence of the First Strains of SARS-CoV-2 Lineage B.1.1.7 in Romania: Genomic Analysis”

学校读者我要写书评

暂无评论

JMIRx Med 2021年第3期2卷

作者： Andrei Lobiuc Mihai Dimian Olga Sturdza Roxana Filip Mihai Covasa Department of Human Health and Development College of Physical Exercise and Sport Stefan cel Mare University of Suceava Suceava Romania Department of Computers Electronics and Automation College of Electrical Engineering and Computer Science Stefan cel Mare University of Suceava Suceava Romania Integrated Center for Research Development and Innovation in Advanced Materials Nanotechnologies and Distributed Systems for Fabrication and Control Stefan cel Mare University of Suceava Suceava Romania Suceava County Emergency Hospital Suceava Romania