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A deep learning system for predicting time to progression of diabetic retinopathy

NATURE MEDICINE 2024年第2期30卷 358-359页

作者： [Anonymous] Shanghai Belt and Road International Joint Laboratory for Intelligent Prevention and Treatment of Metabolic Disorders Department of Computer Science and Engineering School of Electronic Information and Electrical Engineering Shanghai Jiao Tong University Department of Endocrinology and Metabolism Shanghai Sixth People’s Hospital Affiliated to Shanghai Jiao Tong University School of Medicine Shanghai Diabetes Institute Shanghai Clinical Center for Diabetes Shanghai China MOE Key Laboratory of AI School of Electronic Information and Electrical Engineering Shanghai Jiao Tong University Shanghai China Department of Ophthalmology Huadong Sanatorium Wuxi China Department of Ophthalmology Shanghai Sixth People’s Hospital Affiliated to Shanghai Jiao Tong University School of Medicine Shanghai China Department of Ophthalmology and Visual Sciences The Chinese University of Hong Kong Hong Kong China Singapore Eye Research Institute Singapore National Eye Centre Singapore Singapore Department of Computer Science and Engineering The Hong Kong University of Science and Technology Hong Kong China Department of Chemical and Biological Engineering The Hong Kong University of Science and Technology Hong Kong China State Key Laboratory of Ophthalmology Zhongshan Ophthalmic Center Sun Yat-sen University Guangdong Provincial Key Laboratory of Ophthalmology and Visual Science Guangzhou China Department of Ophthalmology Peking Union Medical College Hospital Peking Union Medical College Chinese Academy of Medical Sciences Beijing China Medical Records and Statistics Office Shanghai Sixth People’s Hospital Affiliated to Shanghai Jiao Tong University School of Medicine Shanghai China Department of Geriatrics Tongji Hospital Tongji Medical College Huazhong University of Science and Technology Wuhan China National Engineering Research Center for Big Data Technology and System Services Computing Technology and System Lab Cluster and Grid Computing Lab School of Computer Science and Tech

We developed and validated a deep learning system (termed DeepDR Plus) in a diverse, multiethnic, multi-country dataset to predict personalized risk and time to progression of diabetic retinopathy. We show that DeepDR Plus can be integrated into the clinical workflow to promote individualized intervention strategies for the management of diabetic retinopathy.

关键词： Diabetes complications Machine learning Predictive markers

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A Comprehensive Survey on Tiny Machine Learning for Human Behavior Analysis

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IEEE Internet of Things Journal 2025年

作者： Lamaakal, Ismail Essahraui, Siham Maleh, Yassine Makkaoui, Khalid El Ouahbi, Ibrahim Bouami, Mouncef Filali El-Latif, Ahmed A. Abd Almousa, May Peng, Jialiang Sultan Moulay Slimane University Laboratory LaSTI ENSAK Khouribga Morocco Prince Sultan University EIAS Data Science Lab College of Computer and Information Sciences Center of Excellence in Quantum and Intelligent Computing Riyadh11586 Saudi Arabia Menoufia University Faculty of Science Department of Mathematics and Computer Science Shebin El-Koom32511 Egypt Princess Nourah Bint Abdulrahman University College of Computer and Information Sciences Information Technology Department Riyadh Saudi Arabia Heilongjiang University School of Data Science and Technology Harbin150080 China Nanyang Technological University School of Computer Science and Engineering Nanyang Avenue Singapore639798 Singapore

The integration of Tiny Machine Learning (TinyML) with Human Behavior Analysis (HBA) represents a significant advancement in the field of Artificial Intelligence (AI), enabling real-time, efficient, and privacy-preserving analysis on resource-constrained devices. This paper provides the first comprehensive survey exploring this integration, presenting a detailed overview of TinyML, including its definitions, key concepts and advantages. The survey proposes a systematic taxonomy of TinyML applications in HBA, categorizing state-of-the-art implementations based on their use cases and specific methodologies. Furthermore, the challenges and limitations of integrating TinyML in HBA are thoroughly discussed, including technical constraints, data quality issues, and ethical considerations. Finally, future research directions and open issues are outlined, emphasizing the potential advancements and emerging trends in this field. This survey serves as a foundational resource, guiding researchers and practitioners in harnessing the capabilities of TinyML to advance HBA. © 2014 IEEE.

关键词： Embedded systems

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A Survey on Self-supervised Learning: Algorithms, Applications, and Future Trends

arXiv

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arXiv 2023年

作者： Gui, Jie Chen, Tuo Zhang, Jing Cao, Qiong Sun, Zhenan Luo, Hao Tao, Dacheng School of Cyber Science and Engineering Southeast University with Purple Mountain Laboratories Nanjing210000 China School of Cyber Science and Engineering Southeast University China School of Computer Science The University of Sydney CamperdownNSW2050 Australia College of Computing & Data Science Nanyang Technological University #32 Block N4 #02a-014 50 Nanyang Avenue Singapore639798 Singapore JD Explore Academy Center for Research on Intelligent Perception and Computing Chinese Academy of Sciences Beijing100190 China Alibaba Group Hangzhou310052 China

Deep supervised learning algorithms typically require a large volume of labeled data to achieve satisfactory performance. However, the process of collecting and labeling such data can be expensive and time-consuming. Self-supervised learning (SSL), a subset of unsupervised learning, aims to learn discriminative features from unlabeled data without relying on human-annotated labels. SSL has garnered significant attention recently, leading to the development of numerous related algorithms. However, there is a dearth of comprehensive studies that elucidate the connections and evolution of different SSL variants. This paper presents a review of diverse SSL methods, encompassing algorithmic aspects, application domains, three key trends, and open research questions. Firstly, we provide a detailed introduction to the motivations behind most SSL algorithms and compare their commonalities and differences. Secondly, we explore representative applications of SSL in domains such as image processing, computer vision, and natural language processing. Lastly, we discuss the three primary trends observed in SSL research and highlight the open questions that remain. A curated collection of valuable resources can be accessed at https://***/guijiejie/SSL. Copyright © 2023, The Authors. All rights reserved.

关键词： Contrastive Learning

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PreZ-DGGAN: A Drug Graph GAN Based on Pre-Learning of Implicit Variables 2nd

PreZ-DGGAN: A Drug Graph GAN Based on Pre-Learning of Implic...

引用

2nd International Conference on Applied Intelligence, ICAI 2024

作者： Liu, Yixin Fan, Yueqin Li, Zhipeng Zhang, Qinhu Big Data and Intelligent Computing Research Center Guangxi Academy of Science Nanning530007 China School of Mechanical Engineering Guangxi University Nanning530004 China Ningbo Institute of Digital Twin Eastern Institute of Technology Ningbo315201 China Institute for Regenerative Medicine Medical Innovation Center and State Key Laboratory of Cardiology School of Medicine Shanghai East Hospital Tongji University Shanghai200123 China College of Advanced Agricultural Sciences Zhejiang Agriculture and Forestry University Hangzhou311300 China

ISBN: (纸本)9789819619061

In the field of drug discovery and development, deep learning techniques have become a powerful tool to accelerate the discovery and development of new drugs. In the design and optimization of lead molecules, generative adversarial network and graph neural network are one of the prime techniques for accelerating research and development, because the former is based on the idea of two-player game to learn drug features to generate effective molecules, while the unstructured inputs of the latter are well-suited for the analysis of molecular data. Therefore, this study develops a new graph generative adversarial model, called PreZ-DGGAN, by inserting the graph neural network layer into the generative adversarial network. Within PreZ-DGGAN, the latent variable input of the generator is pre-learned by an improved graph variational autoencoder, which effectively avoids the mode collapse of the generative adversarial network, whereas the hidden layer of the discriminator is graph neural network layer, which is able to better learn the real molecules and judge the generated molecules as true or false. Experiments on two molecule datasets show that the molecules generated by PreZ-DGGAN have higher validity (100% on average) and uniqueness (91.5% on average), and the generated molecules are more diverse in structure. © The Author(s), under exclusive license to Springer Nature Singapore Pte Ltd. 2025.

关键词： Generative adversarial networks

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Visible-Thermal Multiple Object Tracking: Large-scale Video dataset and Progressive Fusion Approach

arXiv

引用

arXiv 2024年

作者： Zhu, Yabin Wang, Qianwu Li, Chenglong Tang, Jin Huang, Zhixiang The Key Laboratory of Intelligent Computing and Signal Processing Ministry of Education Anhui University School of Public Safety and Emergency Management Anhui University of Science and Technology Hefei231131 China School of Artificial Intelligence Anhui University Hefei230601 China Information Materials and Intelligent Sensing Laboratory of Anhui Province Anhui Provincial Key Laboratory of Security Artificial Intelligence School of Artificial Intelligence Anhui University Hefei230601 China Information Materials and Intelligent Sensing Laboratory of Anhui Province Anhui Provincial Key Laboratory of Multimodal Cognitive Computation School of Computer Science and Technology Anhui University Hefei230601 China Center for Big Data and Population Health of IHM China

The complementary benefits from visible and thermal infrared data are widely utilized in various computer vision task, such as visual tracking, semantic segmentation and object detection, but rarely explored in Multiple Object Tracking (MOT). In this work, we contribute a large-scale Visible-Thermal video benchmark for MOT, called VT-MOT. VT-MOT has the following main advantages. 1) The data is large scale and high diversity. VT-MOT includes 582 video sequence pairs, 401k frame pairs from surveillance, drone, and handheld platforms. 2) The cross-modal alignment is highly accurate. We invite several professionals to perform both spatial and temporal alignment frame by frame. 3) The annotation is dense and high-quality. VT-MOT has 3.99 million annotation boxes annotated and double-checked by professionals, including heavy occlusion and object re-acquisition (object disappear and reappear) challenges. To provide a strong baseline, we design a simple yet effective tracking framework, which effectively fuses temporal information and complementary information of two modalities in a progressive manner, for robust visible-thermal MOT. A comprehensive experiment are conducted on VT-MOT and the results prove the superiority and effectiveness of the proposed method compared with state-of-the-art methods. From the evaluation results and analysis, we specify several potential future directions for visible-thermal MOT. The project is released in https://***/wqw123wqw/PFTrack. Copyright © 2024, The Authors. All rights reserved.

关键词： Semantic Segmentation

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Rate-Splitting for Cell-Free Massive MIMO: Performance Analysis and Generative AI Approach

arXiv

引用

arXiv 2024年

作者： Zheng, Jiakang Zhang, Jiayi Du, Hongyang Zhang, Ruichen Niyato, Dusit Dobre, Octavia A. Ai, Bo The School of Electronic and Information Engineering Beijing Jiaotong University Beijing100044 China The Frontiers Science Center for Smart High-speed Railway System Beijing Jiaotong University Beijing100044 China The Department of Electrical and Electronic Engineering University of Hong Kong Pok Fu Lam Hong Kong The College of Computing and Data Science Nanyang Technological University Singapore Faculty of Engineering and Applied Science Memorial University Canada The State Key Laboratory of Rail Traffic Control and Safety Beijing Jiaotong University Beijing100044 China The Frontiers Science Center for Smart High-speed Railway System China Henan Joint International Research Laboratory of Intelligent Networking and Data Analysis Zhengzhou University Zhengzhou450001 China Research Center of Networks and Communications Peng Cheng Laboratory Shenzhen China

Cell-free (CF) massive multiple-input multiple-output (MIMO) provides a ubiquitous coverage to user equipments (UEs) but it is also susceptible to interference. Rate-splitting (RS) effectively extracts data by decoding interference, yet its effectiveness is limited by the weakest UE. In this paper, we investigate an RS-based CF massive MIMO system, which combines strengths and mitigates weaknesses of both approaches. Considering imperfect channel state information (CSI) resulting from both pilot contamination and noise, we derive a closed-form expression for the sum spectral efficiency (SE) of the RS-based CF massive MIMO system under a spatially correlated Rician channel. Moreover, we propose low-complexity heuristic algorithms based on statistical CSI for power-splitting of common messages and power-control of private messages, and genetic algorithm is adopted as a solution for upper bound performance. Furthermore, we formulate a joint optimization problem, aiming to maximize the sum SE of the RS-based CF massive MIMO system by optimizing the power-splitting factor and power-control coefficient. Importantly, we improve a generative AI (GAI) algorithm to address this complex and non-convexity problem by using a diffusion model to obtain solutions. Simulation results demonstrate its effectiveness and practicality in mitigating interference, especially in dynamic environments. Copyright © 2024, The Authors. All rights reserved.

关键词： Genetic algorithms

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Learning Unified Embeddings for Recommendation via Meta-path Semantics 21

Learning Unified Embeddings for Recommendation via Meta-path...

引用

29th ACM International Conference on Multimedia, MM 2021

作者： Hao, Qianxiu Xu, Qianqian Yang, Zhiyong Huang, Qingming Key Laboratory of Intelligent Information Processing Institute of Computing Technology CAS Beijing China School of Computer Science and Technology University of Chinese Academy of Sciences Beijing China Key Laboratory of Big Data Mining and Knowledge Management Chinese Academy of Sciences Beijing China Artificial Intelligence Research Center Peng Cheng Laboratory Shenzhen China

ISBN: (纸本)9781450386517

Heterogeneous information networks (HINs) have become a popular tool to capture complicated user-item relationships in recommendation problems in recent years. As a typical instantiation of HINs, meta-path is introduced in search of higher-level representations of user-item interactions. Though remarkable success has been achieved along this direction, existing meta-path-based recommendation methods face at least one of the following issues: 1) existing methods merely adopt simple meta-path fusion rules, which might be insufficient to exclude inconsistent information of different meta-paths that may hurt model performance;2) the representative power is limited by shallow/stage-wise formulations. To solve these issues, we propose an end-to-end and unified embedding-based recommendation framework with graph-based learning. To address 1), we propose a flexible fusion module to integrate meta-path-based similarities into relative similarities between users and items. To address 2), we take advantage of the powerful representative ability of deep neural networks to learn more complicated and flexible latent embeddings. Finally, empirical studies on real-world datasets demonstrate the effectiveness of our proposed method. © 2021 ACM.

关键词： Embeddings

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GCNs-Based Context-Aware Short Text Similarity Model

GCNs-Based Context-Aware Short Text Similarity Model

引用

International Conference on Pattern Recognition

作者： Xiaoqi Sun Shaochun Wu Yue Liu School of Computer Engineering and Science Shanghai University School of Computer Engineering and Science Shanghai University Shanghai Institute for Advanced Communication and Data Science Shanghai Engineering Research Center of Intelligent Computing System Shanghai China

ISBN: (纸本)9781728188089;9781728188096

Semantic textual similarity is a fundamental task in text mining and natural language processing (NLP), which has profound research value. The essential step for text similarity is text representation learning. Recently, researches have explored the graph convolutional network (GCN) techniques on text representation, since GCN does well in handling complex structures and preserving syntactic information. However, current GCN models are usually limited to very shallow layers due to the vanishing gradient problem, which can not capture non-local dependency information of sentences. In this paper, we propose a GCNs-based context-aware (GCSTS) model that applies iterated GCN blocks to train deeper GCNs. Recurrently employing the same GCN block prevents over-fitting and provides broad effective input width. Combined with dense connections, GCSTS can be trained more deeply. Besides, we use dynamic graph structures in the block, which further extends the receptive field of each vertex in graphs, learning better sentence representations. Experiments show that our model outperforms existing models on several text similarity datasets, while also verify that GCNs-based text representation models can be trained in a deeper manner, rather than being trained in two or three layers.

关键词： Text mining Semantics Syntactics Natural language processing Pattern recognition Task analysis Context modeling

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K-Space-Aware Cross-Modality Score for Quality Assessment of Synthesized Neuroimages

arXiv

引用

arXiv 2023年

作者： Xie, Guoyang Wang, Jinbao Huang, Yawen Lyu, Jiayi Zheng, Feng Zheng, Yefeng Jin, Yaochu Southern University of Science and Technology Department of Computer Science Shenzhen518055 China CATL Department of Intelligent Manufacturing Ningde352000 China Shenzhen University National Engineering Laboratory for Big Data System Computing Technology Shenzhen518060 China Tencent Youtu Lab Jarvis Research Center Shenzhen510310 China University of Chinese Academy of Sciences the School of Engineering Science Beijing100049 China Westlake University the School of Engineering Hangzhou310030 China

The problem of how to assess cross-modality medical image synthesis has been largely unexplored. The most used measures like PSNR and SSIM focus on analyzing the structural features but neglect the crucial lesion location and fundamental k-space speciality of medical images. To overcome this problem, we propose a new metric K-CROSS to spur progress on this challenging problem. Specifically, K-CROSS uses a pre-trained multi-modality segmentation network to predict the lesion location, together with a tumor encoder for representing features, such as texture details and brightness intensities. To further reflect the frequency-specific information from the magnetic resonance imaging principles, both k-space features and vision features are obtained and employed in our comprehensive encoders with a frequency reconstruction penalty. The structure-shared encoders are designed and constrained with a similarity loss to capture the intrinsic common structural information for both modalities. As a consequence, the features learned from lesion regions, k-space, and anatomical structures are all captured, which serve as our quality evaluators. We evaluate the performance by constructing a large-scale cross-modality neuroimaging perceptual similarity (NIRPS) dataset with 6,000 radiologist judgments. Extensive experiments demonstrate that the proposed method outperforms other metrics, especially in comparison with the radiologists on NIRPS. To forster reproducibility and accessibility, the source codeis uploaded to the website: https://***/M-3LAB/K-CROSS © 2023, CC BY.

关键词： Magnetic resonance imaging

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3D Anatomical Structure-Guided Deep Learning for Accurate Diffusion Microstructure Imaging

3D Anatomical Structure-Guided Deep Learning for Accurate Di...

引用

IEEE International Symposium on Biomedical Imaging

作者： Xinrui Ma Jian Cheng Wenxin Fan Ruoyou Wu Yongquan Ye Shanshan Wang Paul C. Lauterbur Research Center for Biomedical Imaging Shenzhen Institute of Advanced Technology Chinese Academy of Sciences Shenzhen Guangdong China University of Chinese Academy of Sciences Beijing China State Key Laboratory of Software Development Environment Beihang University Beijing China Key Laboratory of Data Science and Intelligent Computing Institute of International Innovation Beihang University Hangzhou Zhejiang China Pengcheng Laboratory Shenzhen Guangdong China United Imaging Healthcare Houston TX USA

ISBN: (数字)9798331520526

ISBN: (纸本)9798331520533

Diffusion magnetic resonance imaging (dMRI) is a crucial non-invasive technique for exploring the microstructure of the living human brain. Traditional hand-crafted and model-based tissue microstructure reconstruction methods often require extensive diffusion gradient sampling, which can be time-consuming and limits the clinical applicability of tissue microstructure information. Recent advances in deep learning have shown promise in microstructure estimation; however, accurately estimating tissue microstructure from clinically feasible dMRI scans remains challenging without appropriate constraints. This paper introduces a novel framework that achieves high-fidelity and rapid diffusion microstructure imaging by simultaneously leveraging anatomical information from macro-level priors and mutual information across parameters. This approach enhances time efficiency while maintaining accuracy in microstructure estimation. Experimental results demonstrate that our method outperforms four state-of-the-art techniques, achieving a peak signal-to-noise ratio (PSNR) of 30.51±0.58 and a structural similarity index measure (SSIM) of 0.97±0.004 in estimating parametric maps of multiple diffusion models. Notably, our method achieves a 15× acceleration compared to the dense sampling approach, which typically utilizes 270 diffusion gradients.

关键词： Deep learning PSNR Accuracy Three-dimensional displays Magnetic resonance imaging Estimation Reconstruction algorithms Diffusion models Feature extraction Microstructure

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