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arXiv 2023年

作者： Zhi, Q.J. Bai, J.T. Dai, S. Xu, X. Dang, S.J. Shang, L.H. Zhao, R.S. Li, D. Zhu, W.W. Wang, N. Yuan, J.P. Wang, P. Zhang, L. Feng, Y. Wang, J.B. Wang, S.Q. Wu, Q.D. Dong, A.J. Yang, H. Tian, J. Zhong, W.Q. Luo, X.H. Filipović, Miroslav D. Qiao, G.J. School of Physics and Electronic Science Guizhou Provincial Key Laboratory of Radio Astronomy and Data Processing Guizhou Normal University Guiyang550001 China Xinjiang Astronomical Observatory Chinese Academy of Sciences Xinjiang Urumqi830011 China School of Science Western Sydney University Locked Bag 1797 Penrith South DCNSW2751 Australia School of Mathematical Sciences Guizhou Provincial Key Laboratory of Radio Astronomy and Data Processing Guizhou Normal University Guiyang550001 China National Astronomical Observatories Chinese Academy of Sciences Beijing100101 China University of Chinese Academy of Sciences Beijing100049 China Research Center for Intelligent Computing Platforms Zhejiang Laboratory Hangzhou311100 China Key Laboratory of Radio Astronomy Chinese Academy of Sciences Xinjiang Urumqi830011 China Xinjiang Key Laboratory of Radio Astrophysics 150 Science1-Street Xinjiang Urumqi830011 China Zhejiang Lab Zhejiang Hangzhou311121 China Institute of Optoelectronic Technology Lishui University Lishui323000 China School of Astronomy and Space Science University of Chinese Academy of Sciences Beijing100049 China School of Physics Peking University Beijing100871 China

We present the discovery and timing results of four pulsars discovered in a pilot survey at intermediate Galactic latitudes with the Five-hundred Aperture Spherical Telescope (FAST). Among these pulsars, two belong to the category of millisecond pulsars (MSPs) with spin periods of less than 20 ms. The other two fall under the classification of "mildly recycled" pulsars, with massive white dwarfs as companions. Remarkably, this small survey, covering an area of 4.7 deg2, led to the discovery of four recycled pulsars. Such success underscores the immense potential of future surveys at intermediate Galactic latitudes. In order to assess the potential yield of MSPs, we conducted population simulations and found that both FAST and Parkes new phased array feed surveys, focusing on intermediate Galactic latitudes, have the capacity to uncover several hundred new MSPs. Copyright © 2023, The Authors. All rights reserved.

关键词： Pulsars

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COVID-19 Infection Percentage Estimation from Computed Tomography Scans: Results and Insights from the International Per-COVID-19 Challenge

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Sensors 2024年第5期24卷 1557页

作者： Bougourzi, Fares Distante, Cosimo Dornaika, Fadi Taleb-Ahmed, Abdelmalik Hadid, Abdenour Chaudhary, Suman Yang, Wanting Qiang, Yan Anwar, Talha Breaban, Mihaela Elena Hsu, Chih-Chung Tai, Shen-Chieh Chen, Shao-Ning Tricarico, Davide Chaudhry, Hafiza Ayesha Hoor Fiandrotti, Attilio Grangetto, Marco Spatafora, Maria Ausilia Napoli Ortis, Alessandro Battiato, Sebastiano Institute of Applied Sciences and Intelligent Systems National Research Council of Italy Lecce73100 Italy Laboratoire LISSI University Paris-Est Creteil Paris Vitry sur Seine94400 France Department of Computer Science and Artificial Intelligence University of the Basque Country UPV/EHU Manuel Lardizabal 1 San Sebastian20018 Spain IKERBASQUE Basque Foundation for Science Bilbao48011 Spain UMR 8520 Universite Polytechnique Hauts-de-France Université de Lille CNRS Valenciennes59313 France Sorbonne Center for Artificial Intelligence Sorbonne University of Abu Dhabi P.O. Box 38044 Abu Dhabi United Arab Emirates College of Computer Science and Technology Taiyuan University of Technology Taiyuan030024 China School of Computing National University of Computer and Emerging Sciences Islamabad44000 Pakistan Faculty of Computer Science Alexandru Ioan Cuza University Iasi700506 Romania Institute of Data Science National Cheng Kung University No. 1 University Rd. East Dist. Tainan City701 Taiwan Dipartimento di Informatica Universita degli Studi di Torino Corso Svizzera 185 Torino10149 Italy Department of Mathematics and Computer Science University of Catania Catania95125 Italy

COVID-19 analysis from medical imaging is an important task that has been intensively studied in the last years due to the spread of the COVID-19 pandemic. In fact, medical imaging has often been used as a complementary or main tool to recognize the infected persons. On the other hand, medical imaging has the ability to provide more details about COVID-19 infection, including its severity and spread, which makes it possible to evaluate the infection and follow-up the patient’s state. CT scans are the most informative tool for COVID-19 infection, where the evaluation of COVID-19 infection is usually performed through infection segmentation. However, segmentation is a tedious task that requires much effort and time from expert radiologists. To deal with this limitation, an efficient framework for estimating COVID-19 infection as a regression task is proposed. The goal of the Per-COVID-19 challenge is to test the efficiency of modern deep learning methods on COVID-19 infection percentage estimation (CIPE) from CT scans. Participants had to develop an efficient deep learning approach that can learn from noisy data. In addition, participants had to cope with many challenges, including those related to COVID-19 infection complexity and crossdataset scenarios. This paper provides an overview of the COVID-19 infection percentage estimation challenge (Per-COVID-19) held at MIA-COVID-2022. Details of the competition data, challenges, and evaluation metrics are presented. The best performing approaches and their results are described and discussed. © 2024 by the authors.

关键词： COVID-19

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Investigating 16 Open Clusters in the Kepler/K2 - Gaia DR3 field. I. Membership, Binary, and Rotation

arXiv

引用

arXiv 2023年

作者： Long, Liu Bi, Shaolan Zhang, Jinghua Zhang, Xianfei Zhang, Liyun Ge, Zhishuai Li, Tanda Chen, Xunzhou Li, YaGuang Ye, LiFei Sun, TianCheng Zhou, JianZhao Institute for Frontiers in Astronomy and Astrophysics Beijing Normal University Beijing102206 China Department of Astronomy Beijing Normal University Beijing100875 China South-Western Institute for Astronomy Research Yunnan University Chenggong District Kunming650500 China College of Physics Guizhou University Guiyang550025 China State Key Laboratory of Public Big Data Guizhou University Guiyang550025 China Beijing Planetarium Beijing Academy of Science and Technology Beijing100044 China Research Center for Intelligent Computing Platforms Zhejiang Laboratory Hangzhou311100 China School of Physics University of Sydney NSW2006 Australia Stellar Astrophysics Centre Department of Physics and Astronomy Aarhus University Ny Munkegade 120 Aarhus CDK-8000 Denmark

Using data from the Gaia data Release 3 (Gaia DR3) and Kepler/K2, we present a catalog of 16 open clusters with ages ranging from 4 to 4000 Myr, which provides detailed information on membership, binary systems, and rotation. We assess the memberships in 5D phase space, and estimate the basic parameters of each cluster. Among the 20,160 members, there are 4,381 stars identified as binary candidates and 49 stars as blue straggler stars. The fraction of binaries vary in each cluster, and the range between 9% to 44%. We obtain the rotation periods of 5,467 members, of which 4,304 are determined in this work. To establish a benchmark for the rotation-age-color relation, we construct color-period diagrams. We find that the rotational features of binaries are similar to that of single stars, while features for binaries are more scattered in the rotation period. Moreover, the morphology of the color-period relationship is already established for Upper Scorpius at the age of 19 Myr, and some stars of varying spectral types (i.e. FG-, K-, and M-type) show different spin-down rates after the age of ∼ 110 Myr. By incorporating the effects of stalled spin-down into our analysis, we develop an empirical rotation-age-color relation, which is valid with ages between 700 - 4000 Myr and colors corresponding to a range of 0.5 BP − GRP)0 Copyright © 2023, The Authors. All rights reserved.

关键词： Color

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ADAM CHALLENGE: DETECTING AGE-RELATED MACULAR DEGENERATION FROM FUNDUS IMAGES

arXiv

引用

arXiv 2022年

作者： Fang, Huihui Li, Fei Fu, Huazhu Sun, Xu Cao, Xingxing Lin, Fengbin Son, Jaemin Kim, Sunho Quellec, Gwenole Matta, Sarah Shankaranarayana, Sharath M. Chen, Yi-Ting Wang, Chuen-Heng Shah, Nisarg A. Lee, Chia-Yen Hsu, Chih-Chung Xie, Hai Lei, Baiying Baid, Ujjwal Innani, Shubham Dang, Kang Shi, Wenxiu Kamble, Ravi Singhal, Nitin Wang, Ching-Wei Lo, Shih-Chang Orlando, José Ignacio Bogunović, Hrvoje Zhang, Xiulan Xu, Yanwu The ADAM Challenge State Key Laboratory of Ophthalmology Zhongshan Ophthalmic Center Sun Yat-Sen University Guangdong Provincial Key Laboratory of Ophthalmology and Visual Science Guangzhou China Intelligent Healthcare Unit Baidu Inc. Beijing China The Institute of High Performance Computing Agency for Science Technology and Research Singapore CONICET Yatiris lab of Pladema Institute Tandil Argentina Department of Ophthalmology and Optometry Medical University of Vienna Vienna Austria VUNO Inc Seoul Korea Republic of Inserm UMR 1101 BrestF-29200 France Univ Bretagne Occidentale BrestF-29200 France Zasti India Pvt. Ltd. India Graphen.Inc Muen Biomedical and Optoelectronics Technologies Inc Taiwan Department of Electrical Engineering Indian Institute of Technology Rajasthan Jodhpur India Department of Electrical Engineering National United University Taiwan Institute of Data Science Department of Statistics National Cheng Kung University Taiwan Shenzhen University Shenzhen China SGGS Institute of Engineering and Technology Nanded India Suzhou Tisu Information Technology Co. Ltd China AIRA Matrix Mumbai India Graduate Institute of Biomedical Engineering National Taiwan University of Science and Technology Taiwan

Age-related macular degeneration (AMD) is the leading cause of visual impairment among elderly in the world. Early detection of AMD is of great importance, as the vision loss caused by this disease is irreversible and permanent. Color fundus photography is the most cost-effective imaging modality to screen for retinal disorders. Cutting edge deep learning based algorithms have been recently developed for automatically detecting AMD from fundus images. However, there are still lack of a comprehensive annotated dataset and standard evaluation benchmarks. To deal with this issue, we set up the Automatic Detection challenge on Age-related Macular degeneration (ADAM), which was held as a satellite event of the ISBI 2020 conference. The ADAM challenge consisted of four tasks which cover the main aspects of detecting and characterizing AMD from fundus images, including detection of AMD, detection and segmentation of optic disc, localization of fovea, and detection and segmentation of lesions. As part of the ADAM challenge, we have released a comprehensive dataset of 1200 fundus images with AMD diagnostic labels, pixel-wise segmentation masks for both optic disc and AMD-related lesions (drusen, exudates, hemorrhages and scars, among others), as well as the coordinates corresponding to the location of the macular fovea. A uniform evaluation framework has been built to make a fair comparison of different models using this dataset. During the ADAM challenge, 610 results were submitted for online evaluation, with 11 teams finally participating in the onsite challenge. This paper introduces the challenge, the dataset and the evaluation methods, as well as summarizes the participating methods and analyzes their results for each task. In particular, we observed that the ensembling strategy and the incorporation of clinical domain knowledge were the key to improve the performance of the deep learning models. © 2022, CC BY-NC-ND.

关键词： Cost effectiveness

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Distributed Computation Offloading and Power Control for UAV-Enabled Internet of Medical Things

引用

ACM Transactions on Internet Technology 1000年

作者： Jiakun Gao Xiaolong Xu Lianyong Qi Wanchun Dou Xiaoyu Xia Xiaokang Zhou School of Software Nanjing University of Information Science and Technology NanJing China School of Software Nanjing University of Information Science and Technology NanJing China and Jiangsu Province Engineering Research Center of Advanced Computing and Intelligent Services Jiangsu Collaborative Innovation Center of Atmospheric Environment and Equipment Technology (CICAEET) Nanjing University of Information Science and Technology Nanjing China College of Computer Science and Technology China University of Petroleum (East China) QingDao China and State Key Laboratory for Novel Software Technology Nanjing University Nanjing China State Key Laboratory for Novel Software Technology Nanjing University Nanjing China School of Computer Technology RMIT University Victoria Australia Faculty of Data Science Shiga University Hikone Japan

The advancement of the Internet of Medical Things (IoMT) has led to the emergence of various health and emotion care services, e.g., health monitoring. To cater to increasing computational requirements of IoMT services, Mobile Edge computing (MEC) has emerged as an indispensable technology in smart health. Benefiting from the cost-effectiveness of deployment, unmanned aerial vehicles (UAVs) equipped with MEC servers in Non-Orthogonal Multiple Access (NOMA) have emerged as a promising solution for providing smart health services in proximity to medical devices (MDs). However, the escalating number of MDs and the limited availability of communication resources of UAVs give rise to a significant increase in transmission latency. Moreover, due to the limited communication range of UAVs, the geographically-distributed MDs lead to workload imbalance of UAVs, which deteriorates the service response delay. To this end, this paper proposes a UAV-enabled Distributed computation Offloading and Power control method with Multi-Agent, named DOPMA, for NOMA-based IoMT environment. Specifically, this paper introduces computation and transmission queue models to analyze the dynamic characteristics of task execution latency and energy consumption. Moreover, a credit assignment scheme-based reward function is designed considering both system-level rewards and rewards tailored to each MD, and an improved multi-agent deep deterministic policy gradient algorithm is developed to derive offloading and power control decisions independently. Extensive simulations demonstrate that the proposed method outperforms existing schemes, achieving \(7.1\%\) reduction in energy consumption and \(16\%\) decrease in average delay.

关键词： Internet of Medical Things (IoMT) Mobile Edge computing (MEC) Unmanned Aerial Vehicles (UAV) Non-Orthogonal Multiple Access (NOMA)

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Why is the Winner the Best?

Why is the Winner the Best?

引用

Conference on Computer Vision and Pattern Recognition (CVPR)

作者： M. Eisenmann A. Reinke V. Weru M. D. Tizabi F. Isensee T. J. Adler S. Ali V. Andrearczyk M. Aubreville U. Baid S. Bakas N. Balu S. Bano J. Bernal S. Bodenstedt A. Casella V. Cheplygina M. Daum M. De Bruijne A. Depeursinge R. Dorent J. Egger D. G. Ellis S. Engelhardt M. Ganz N. Ghatwary G. Girard P. Godau A. Gupta L. Hansen K. Harada M. Heinrich N. Heller A. Hering A. Huaulmé P. Jannin A. E. Kavur O. Kodym M. Kozubek J. Li H. Li J. Ma C. Martín-Isla B. Menze A. Noble V. Oreiller N. Padoy S. Pati K. Payette T. Rädsch J. Rafael-Patiño V. Singh Bawa S. Speidel C. H. Sudre K. Van Wijnen M. Wagner D. Wei A. Yamlahi M. H. Yap C. Yuan M. Zenk A. Zia D. Zimmerer D. Aydogan B. Bhattarai L. Bloch R. Brüngel J. Cho C. Choi Q. Dou I. Ezhov C. M. Friedrich C. Fuller R. R. Gaire A. Galdran Á. García Faura M. Grammatikopoulou S. Hong M. Jahanifar I. Jang A. Kadkhodamohammadi I. Kang F. Kofler S. Kondo H. Kuijf M. Li M. Luu T. Martinčič P. Morais M. A. Naser B. Oliveira D. Owen S. Pang J. Park S. Park S. Płotka E. Puybareau N. Rajpoot K. Ryu N. Saeed A. Shephard P. Shi D. Štepec R. Subedi G. Tochon H. R. Torres H. Urien J. L. Vilaça K. A. Wahid H. Wang J. Wang L. Wang X. Wang B. Wiestler M. Wodzinski F. Xia J. Xie Z. Xiong S. Yang Y. Yang Z. Zhao K. Maier-Hein P. F. Jäger A. Kopp-Schneider L. Maier-Hein Division of Intelligent Medical Systems German Cancer Research Center (DKFZ) Heidelberg Germany Helmholtz Imaging German Cancer Research Center (DKFZ) Heidelberg Germany Faculty of Mathematics and Computer Science Heidelberg University Heidelberg Germany Division of Biostatistics German Cancer Research Center (DKFZ) Heidelberg Germany Division of Medical Image Computing German Cancer Research Center (DKFZ) Heidelberg Germany Faculty of Engineering and Physical Sciences School of Computing University of Leeds Leeds UK Institute of Informatics School of Management HES-SO Valais-Wallis University of Applied Sciences and Arts Western Switzerland Sierre Switzerland Department of Nuclear Medicine and Molecular Imaging Lausanne University Hospital Lausanne Switzerland Technische Hochschule Ingolstadt Ingolstadt Germany Center for Artificial Intelligence and Data Science for Integrated Diagnostics (AI2D) and Center for Biomedical Image Computing and Analytics (CBICA) University of Pennsylvania Philadelphia PA USA Department of Pathology and Laboratory Medicine Perelman School of Medicine University of Pennsylvania Philadelphia PA USA Department of Radiology Perelman School of Medicine University of Pennsylvania Philadelphia PA USA Department of Radiology University of Washington Seattle WA USA Department of Computer Science Wellcome/EPSRC Centre for Interventional and Surgical Sciences (WEISS) University College London London UK Universitat Autònoma de Barcelona & Computer Vision Center Barcelona Spain Division of Translational Surgical Oncology National Center for Tumor Diseases (NCT/UCC) Dresden Dresden Germany Department of Advanced Robotics Istituto Italiano di Tecnologia Italy Department of Electronics Information and Bioengineering Politecnico di Milano Milan Italy IT University of Copenhagen Copenhagen Denmark Department of General Visceral and Transplantation Surgery Heidelberg University Hospital Heidelberg Germany Department of Radiology and Nuc

International benchmarking competitions have become fundamental for the comparative performance assessment of image analysis methods. However, little attention has been given to investigating what can be learnt from these competitions. Do they really generate scientific progress? What are common and successful participation strategies? What makes a solution superior to a competing method? To address this gap in the literature, we performed a multicenter study with all 80 competitions that were conducted in the scope of IEEE ISBI 2021 and MICCAI 2021. Statistical analyses performed based on comprehensive descriptions of the submitted algorithms linked to their rank as well as the underlying participation strategies revealed common characteristics of winning solutions. These typically include the use of multi-task learning (63%) and/or multi-stage pipelines (61%), and a focus on augmentation (100%), image preprocessing (97%), data curation (79%), and post-processing (66%). The “typical” lead of a winning team is a computer scientist with a doctoral degree, five years of experience in biomedical image analysis, and four years of experience in deep learning. Two core general development strategies stood out for highly-ranked teams: the reflection of the metrics in the method design and the focus on analyzing and handling failure cases. According to the organizers, 43% of the winning algorithms exceeded the state of the art but only 11% completely solved the respective domain problem. The insights of our study could help researchers (1) improve algorithm development strategies when approaching new problems, and (2) focus on open research questions revealed by this work.

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CMRxRecon2024: A Multi-Modality, Multi-View K-Space dataset Boosting Universal Machine Learning for Accelerated Cardiac MRI

arXiv

引用

arXiv 2024年

作者： Wang, Zi Wang, Fanwen Qin, Chen Lyu, Jun Ouyang, Cheng Wang, Shuo Li, Yan Yu, Mengyao Zhang, Haoyu Guo, Kunyuan Shi, Zhang Li, Qirong Xu, Ziqiang Zhang, Yajing Li, Hao Hua, Sha Chen, Binghua Sun, Longyu Sun, Mengting Li, Qin Chu, Ying-Hua Bai, Wenjia Qin, Jing Zhuang, Xiahai Prieto, Claudia Young, Alistair Markl, Michael Wang, He Wu, Lianming Yang, Guang Qu, Xiaobo Wang, Chengyan Department of Electronic Science Fujian Provincial Key Laboratory of Plasma and Magnetic Resonance National Institute for Data Science in Health and Medicine Xiamen University Xiamen China Department of Bioengineering and Imperial-X Imperial College London London United Kingdom Cardiovascular Research Centre Royal Brompton Hospital London United Kingdom Department of Electrical and Electronic Engineering & Imperial-X Imperial College London London United Kingdom Psychiatry Neuroimaging Laboratory Brigham and Women’s Hospital Harvard Medical School Boston United States Department of Computing Department of Brain Sciences Imperial College London London United Kingdom Digital Medical Research Center School of Basic Medical Sciences Fudan University Shanghai China Department of Radiology Ruijin Hospital Shanghai Jiao Tong University School of Medicine Shanghai China Human Phenome Institute Fudan University Shanghai China Department of Radiology Zhongshan Hospital Fudan University Shanghai China School of Health Science and Engineering University of Shanghai for Science and Technology Shanghai China GE Healthcare Beijing China Institute of Science and Technology for Brain-Inspired Intelligence Fudan University Shanghai China Department of Cardiovascular Medicine Ruijin Hospital Lu Wan Branch Shanghai Jiao Tong University School of Medicine Shanghai China Department of Radiology Ren Ji Hospital School of Medicine Shanghai Jiao Tong University Shanghai China Siemens Healthineers Ltd. Shanghai China School of Nursing The Hong Kong Polytechnic University Hong Kong School of Data Science Fudan University Shanghai China School of Engineering Pontificia Universidad Católica de Chile Santiago Chile School of Biomedical Engineering and Imaging Sciences King’s College London London United Kingdom Millenium Institute for Intelligent Healthcare Engineering Santiago Chile Department of Radiology Feinberg School of Medicine Northwestern University Chicago Unit

The released CMRxRecon2024 dataset is currently the largest and most protocol-diverse publicly available k-space dataset including multi-modality and multi-view cardiac MRI data from 330 healthy volunteers, and each o... 详细信息

关键词： Adversarial machine learning

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BigNeuron: a resource to benchmark and predict performance of algorithms for automated tracing of neurons in light microscopy datasets

引用

Nature methods 2023年第6期20卷 824-835页

作者： Linus Manubens-Gil Zhi Zhou Hanbo Chen Arvind Ramanathan Xiaoxiao Liu Yufeng Liu Alessandro Bria Todd Gillette Zongcai Ruan Jian Yang Miroslav Radojević Ting Zhao Li Cheng Lei Qu Siqi Liu Kristofer E Bouchard Lin Gu Weidong Cai Shuiwang Ji Badrinath Roysam Ching-Wei Wang Hongchuan Yu Amos Sironi Daniel Maxim Iascone Jie Zhou Erhan Bas Eduardo Conde-Sousa Paulo Aguiar Xiang Li Yujie Li Sumit Nanda Yuan Wang Leila Muresan Pascal Fua Bing Ye Hai-Yan He Jochen F Staiger Manuel Peter Daniel N Cox Michel Simonneau Marcel Oberlaender Gregory Jefferis Kei Ito Paloma Gonzalez-Bellido Jinhyun Kim Edwin Rubel Hollis T Cline Hongkui Zeng Aljoscha Nern Ann-Shyn Chiang Jianhua Yao Jane Roskams Rick Livesey Janine Stevens Tianming Liu Chinh Dang Yike Guo Ning Zhong Georgia Tourassi Sean Hill Michael Hawrylycz Christof Koch Erik Meijering Giorgio A Ascoli Hanchuan Peng Institute for Brain and Intelligence Southeast University Nanjing China. Microsoft Corporation Redmond WA USA. Tencent AI Lab Bellevue WA USA. Computing Environment and Life Sciences Directorate Argonne National Laboratory Lemont IL USA. Kaya Medical Seattle WA USA. University of Cassino and Southern Lazio Cassino Italy. Center for Neural Informatics Structures and Plasticity Krasnow Institute for Advanced Study George Mason University Fairfax VA USA. Faculty of Information Technology Beijing University of Technology Beijing China. Beijing International Collaboration Base on Brain Informatics and Wisdom Services Beijing China. Nuctech Netherlands Rotterdam the Netherlands. Janelia Research Campus Howard Hughes Medical Institute Ashburn VA USA. Department of Electrical and Computer Engineering University of Alberta Edmonton Alberta Canada. Ministry of Education Key Laboratory of Intelligent Computation and Signal Processing Anhui University Hefei China. Paige AI New York NY USA. Scientific Data Division and Biological Systems and Engineering Division Lawrence Berkeley National Lab Berkeley CA USA. Helen Wills Neuroscience Institute and Redwood Center for Theoretical Neuroscience UC Berkeley Berkeley CA USA. RIKEN AIP Tokyo Japan. Research Center for Advanced Science and Technology (RCAST) The University of Tokyo Tokyo Japan. School of Computer Science University of Sydney Sydney New South Wales Australia. Texas A&M University College Station TX USA. Cullen College of Engineering University of Houston Houston TX USA. Graduate Institute of Biomedical Engineering National Taiwan University of Science and Technology Taipei Taiwan. National Centre for Computer Animation Bournemouth University Poole UK. PROPHESEE Paris France. Department of Neuroscience Columbia University New York NY USA. Mortimer B. Zuckerman Mind Brain Behavior Institute Columbia University New York NY USA. Department of Computer Science Northern Illinois Universit

BigNeuron is an open community bench-testing platform with the goal of setting open standards for accurate and fast automatic neuron tracing. We gathered a diverse set of image volumes across several species that is representative of the data obtained in many neuroscience laboratories interested in neuron tracing. Here, we report generated gold standard manual annotations for a subset of the available imaging datasets and quantified tracing quality for 35 automatic tracing algorithms. The goal of generating such a hand-curated diverse dataset is to advance the development of tracing algorithms and enable generalizable benchmarking. Together with image quality features, we pooled the data in an interactive web application that enables users and developers to perform principal component analysis, t-distributed stochastic neighbor embedding, correlation and clustering, visualization of imaging and tracing data, and benchmarking of automatic tracing algorithms in user-defined data subsets. The image quality metrics explain most of the variance in the data, followed by neuromorphological features related to neuron size. We observed that diverse algorithms can provide complementary information to obtain accurate results and developed a method to iteratively combine methods and generate consensus reconstructions. The consensus trees obtained provide estimates of the neuron structure ground truth that typically outperform single algorithms in noisy datasets. However, specific algorithms may outperform the consensus tree strategy in specific imaging conditions. Finally, to aid users in predicting the most accurate automatic tracing results without manual annotations for comparison, we used support vector machine regression to predict reconstruction quality given an image volume and a set of automatic tracings.

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CHAOS Challenge - Combined (CT-MR) healthy abdominal organ segmentation

arXiv

引用

arXiv 2020年

作者： Kavur, A. Emre Gezer, N. Sinem Barış, Mustafa Conze, Pierre-Henri Groza, Vladimir Pham, Duc Duy Chatterjee, Soumick Ernst, Philipp Özkan, Savaş Baydar, Bora Lachinov, Dmitry Han, Shuo Pauli, Josef Isensee, Fabian Perkonigg, Matthias Sathish, Rachana Rajan, Ronnie Aslan, Sinem Sheet, Debdoot Dovletov, Gurbandurdy Speck, Oliver Nürnberger, Andreas Maier-Hein, Klaus H. Akar, Gözde Bozdagı Ünal, Gözde Dicle, Oguz Selver, M. Alper Graduate School of Natural and Applied Sciences Dokuz Eylul University Izmir Turkey Department of Radiology Faculty Of Medicine Dokuz Eylul University Izmir Turkey Dept. of Ophthalmology and Optometry Medical Uni. of Vienna Austria Intelligent Systems Faculty of Engineering University of Duisburg-Essen Germany Division of Medical Image Computing German Cancer Research Center Heidelberg Germany CIR Lab Dept of Biomedical Imaging and Image-guided Therapy Medical Uni. of Vienna Austria IMT Atlantique LaTIM UMR 1101 Brest France Department of Electrical and Electronics Engineering Middle East Technical University Ankara Turkey Department of Electrical Engineering Indian Institute of Technology Kharagpur India School of Medical Science and Technology Indian Institute of Technology Kharagpur India Ca’ Foscari University of Venice ECLT DAIS Venice Italy Ege University International Computer Institute Izmir Turkey Johns Hopkins University Baltimore United States Data and Knowledge Engineering Group Otto von Guericke University Magdeburg Germany Magnetic Resonance Otto von Guericke University Magdeburg Germany Median Technologies Valbonne France Department of Computer Engineering Istanbul Technical University Istanbul Turkey Department of Electrical and Electronics Engineering Dokuz Eylul University Izmir Turkey

—Segmentation of abdominal organs has been a comprehensive, yet unresolved, research field for many years. In the last decade, intensive developments in deep learning (DL) have introduced new state-of-the-art segmentation systems. Despite outperforming the overall accuracy of existing systems, the effects of DL model properties and parameters on the performance is hard to interpret. This makes comparative analysis a necessary tool to achieve explainable studies and systems. Moreover, the performance of DL for emerging learning approaches such as cross-modality and multi-modal tasks have been rarely discussed. In order to expand the knowledge in these topics, CHAOS – Combined (CT-MR) Healthy Abdominal Organ Segmentation challenge has been organized in the IEEE International Symposium on Biomedical Imaging (ISBI), 2019, in Venice, Italy. Despite a large number of the previous abdomen related challenges, the majority of which are focused on tumor/lesion detection and/or classification with a single modality, CHAOS providesboth abdominal CT and MR data from healthy subjects. Five different and complementary tasks have been designed to analyze the capabilities of the current approaches from multiple perspectives. The results are investigated thoroughly, compared with manual annotations and interactive methods. The outcomes are reported in detail to reflect the latest advancements in the field. CHAOS challenge and data will be available online to provide a continuous benchmark resource for segmentation. Copyright © 2020, The Authors. All rights reserved.

关键词： Medical imaging

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Harmonized-Multinational qEEG norms (HarMNqEEG)

引用

NEUROIMAGE 2022年 256卷 119190-119190页

作者： Li, Min Wang, Ying Lopez-Naranjo, Carlos Hu, Shiang Reyes, Ronaldo Cesar Garcia Paz-Linares, Deirel Areces-Gonzalez, Ariosky Hamid, Aini Ismafairus Abd Evans, Alan C. Savostyanov, Alexander N. Calzada-Reyes, Ana Villringer, Arno Tobon-Quintero, Carlos A. Garcia-Agustin, Daysi Yao, Dezhong Dong, Li Aubert-Vazquez, Eduardo Reza, Faruque Razzaq, Fuleah Abdul Omar, Hazim Abdullah, Jafri Malin Galler, Janina R. Ochoa-Gomez, John F. Prichep, Leslie S. Galan-Garcia, Lidice Morales-Chacon, Lilia Valdes-Sosa, Mitchell J. Trondle, Marius Zulkifly, Mohd Faizal Mohd Rahman, Muhammad Riddha Bin Abdul Milakhina, Natalya S. Langer, Nicolas Rudych, Pavel Koenig, Thomas Virues-Alba, Trinidad A. Lei, Xu Bringas-Vega, Maria L. Bosch-Bayard, Jorge F. Valdes-Sosa, Pedro Antonio [a]The Clinical Hospital of Chengdu Brain Science Institute MOE Key Lab for Neuroinformation School of Life Science and Technology University of Electronic Science and Technology of China Chengdu China [b]Cuban Center for Neurocience La Habana Cuba [c]McGill Centre for Integrative Neuroscience Ludmer Centre for Neuroinformatics and Mental Health Montreal Neurological Institute Canada [d]Department of Neurosciences School of Medical Sciences Universiti Sains Malaysia Universiti Sains Malaysia Health Campus Kota Bharu Kelantan 16150 Malaysia [e]Brain and Behaviour Cluster School of Medical Sciences Universiti Sains Malaysia Health Campus Kota Bharu Kelantan 16150 Malaysia [f]Hospital Universiti Sains Malaysia Universiti Sains Malaysia Health Campus Kota Bharu Kelantan 16150 Malaysia [g]Humanitarian Institute Novosibirsk State University Novosibirsk 630090 Russia [h]Laboratory of Psychophysiology of Individual Differences Federal State Budgetary Scientific Institution Scientific Research Institute of Neurosciences and Medicine Novosibirsk 630117 Russia [i]Laboratory of Psychological Genetics at the Institute of Cytology and Genetics Siberian Branch of the Russian Academy of Sciences Novosibirsk 630090 Russia [j]University of Pinar del Río “Hermanos Saiz Montes de Oca” Pinar del Río Cuba [k]Department of Neurology Max Planck Institute for Human Cognitive and Brain Sciences Leipzig Germany [l]Department of Cognitive Neurology University Hospital Leipzig Leipzig Germany [m]Center for Stroke Research Charité-Universitätsmedizin Berlin Berlin Germany [n]Grupo Neuropsicología y Conducta - GRUNECO Faculty of Medicine Universidad de Antioquia Colombia [o]Research Department Institución Prestadora de Servicios de Salud IPS Universitaria Colombia [p]The Cuban center aging longevity and health Havana Cuba [q]Research Unit of NeuroInformation Chinese Academy of Medical Sciences Chengdu 2019RU035 China [r]School of Electrical Engineering Zhengzhou University Zhengzhou 4500

This paper extends frequency domain quantitative electroencephalography (qEEG) methods pursuing higher sensitivity to detect Brain Developmental Disorders. Prior qEEG work lacked integration of cross-spectral information omitting important functional connectivity descriptors. Lack of geographical diversity precluded accounting for site-specific variance, increasing qEEG nuisance variance. We ameliorate these weaknesses. (i) Create lifespan Riemannian multinational qEEG norms for cross-spectral tensors. These norms result from the HarMNqEEG project fostered by the Global Brain Consortium. We calculate the norms with data from 9 countries, 12 devices, and 14 studies, including 1564 subjects. Instead of raw data, only anonymized metadata and EEG cross spectral tensors were shared. After visual and automatic quality control, developmental equations for the mean and standard deviation of qEEG traditional and Riemannian DPs were calculated using additive mixed-effects models. We demonstrate qEEG "batch effects " and provide methods to calculate harmonized z-scores. (ii) We also show that harmonized Riemannian norms produce z-scores with increased diagnostic accuracy predicting brain dysfunction produced by malnutrition in the first year of life and detecting COVID induced brain dysfunction. (iii) We offer open code and data to calculate different individual z-scores from the HarMNqEEG dataset. These results contribute to developing bias-free, low-cost neuroimaging technologies applicable in various health settings.

关键词： Quantitative EEG EEG cross-spectrum Riemannian geometry Batch effects Z-score Harmonization Malnutrition Covid induced brain dysfunction Developmental Brain Chart

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