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Identification of Clinical Features Associated with Mortality in COVID-19 Patients

Operations research Forum 2023年第1期4卷 1-20页

作者： Eskandarian, Rahimeh Alizadehsani, Roohallah Behjati, Mohaddeseh Zahmatkesh, Mehrdad Sani, Zahra Alizadeh Haddadi, Azadeh Kakhi, Kourosh Roshanzamir, Mohamad Shoeibi, Afshin Hussain, Sadiq Khozeimeh, Fahime Darbandy, Mohammad Tayarani Joloudari, Javad Hassannataj Lashgari, Reza Khosravi, Abbas Nahavandi, Saeid Islam, Sheikh Mohammed Shariful Internal Medicine Research Center Semnan University of Medical Sciences Semnan Iran Institute for Intelligent Systems Research and Innovation (IISRI) Deakin University Victoria Australia Rajaei Cardiovascular Medical and Research Center Iran University of Medical Sciences Tehran Iran Omid Hospital Iran University of Medical Sciences Tehran Iran Department of Biology Faculty of Basic Sciences Shahrekord Branch Islamic Azad University Shahrekord Iran Department of Computer Engineering Faculty of Engineering Fasa University Fasa 74617-81189 Iran Data Science and Computational Intelligence Institute University of Granada Granada Spain System Administrator Dibrugarh University Assam 786004 India School of Architecture Islamic Azad University Taft Taft *** Iran Department of Computer Engineering Faculty of Engineering University of Birjand Birjand Iran Department of Computer Engineering Amol Institute of Higher Education Amol Iran Institute of Medical Science and Technology Shahid Beheshti University Tehran Iran School of Engineering and Applied Sciences Harvard Paulson Harvard University Allston 02134 MA United States Institute for Physical Activity and Nutrition School of Exercise and Nutrition Sciences Deakin University Geelong 3220 VIC Australia Cardiovascular Division The George Institute for Global Health Newtown Australia Sydney Medical School University of Sydney Camperdown Australia

Understanding clinical features and risk factors associated with COVID-19 mortality is needed to early identify critically ill patients, initiate treatments and prevent mortality. A retrospective study on COVID-19 patients referred to a tertiary hospital in Iran between March and November 2020 was conducted. COVID-19-related mortality and its association with clinical features including headache, chest pain, symptoms on computerized tomography (CT), hospitalization, time to infection, history of neurological disorders, having a single or multiple risk factors, fever, myalgia, dizziness, seizure, abdominal pain, nausea, vomiting, diarrhoea and anorexia were investigated. Based on the investigation outcome, decision tree and dimension reduction algorithms were used to identify the aforementioned risk factors. Of the 3008 patients (mean age 59.3 ± 18.7 years, 44% women) with COVID-19, 373 died. There was a significant association between COVID-19 mortality and old age, headache, chest pain, low respiratory rate, oxygen saturation < 93%, need for a mechanical ventilator, having symptoms on CT, hospitalization, time to infection, neurological disorders, cardiovascular diseases and having a risk factor or multiple risk factors. In contrast, there was no significant association between mortality and gender, fever, myalgia, dizziness, seizure, abdominal pain, nausea, vomiting, diarrhoea and anorexia. Our results might help identify early symptoms related to COVID-19 and better manage patients according to the extracted decision tree. The proposed ML models identified a number of clinical features and risk factors associated with mortality in COVID-19 patients. These models if implemented in a clinical setting might help to early identify patients needing medical attention and care. However, more studies are needed to confirm these findings. © 2023, The Author(s).

关键词： COVID‐19 Machine learning Mortality Risk factors Symptoms

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A Reinforcement Learning Based Dynamic Multi-Objective Constrained Evolutionary Algorithm for Open-Pit Mine Truck Scheduling

A Reinforcement Learning Based Dynamic Multi-Objective Const...

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Chinese Automation Congress (CAC)

作者： Junxiang Qiu Changhe Li Shengxiang Yang Engineering Research Center of Intelligent Technology for Geo- Exploration Ministry of Education School of Automation China University of Geosciences Hubei Key Laboratory of Advanced Control and Intelligent Automation for Complex Systems Wuhan China School of Computer Science and Informatics De Montfort University Leicester UK

Aiming at the truck scheduling problem in the open-pit mine scenario, a truck scheduling model based on real-time ore blending is established, and an adaptive evolution algorithm for truck scheduling based on DCNSGA-III is proposed. In the established scheduling model, the real-time grade variance of the crushing plant is minimized as one of the optimization objectives, and the Q-learning algorithm is introduced to adaptively select one of the most effective operators during the search process. Experiments show that the proposed method can effectively control the grade fluctuation of the ore flow and better scheduling schemes are obtained in comparison with algorithms equipped with the traditional search operator selection methods.

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Correction: Materials laboratories of the future for alloys, amorphous, and composite materials (MRS Bulletin, (2025), 50, 2, (190-207), 10.1557/s43577-024-00846-y)

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MRS Bulletin 2025年 1-2页

作者： Banerjee, Sarbajit Meng, Y. Shirley Minor, Andrew M. Zhang, Minghao Zaluzec, Nestor J. Chan, Maria K.Y. Seidler, Gerald McComb, David W. Agar, Joshua Mukherjee, Partha P. Melot, Brent Chapman, Karena Guiton, Beth S. Klie, Robert F. McCue, Ian D. Voyles, Paul M. Robertson, Ian Li, Ling Chi, Miaofang Destino, Joel F. Devaraj, Arun Marquis, Emmanuelle A. Segre, Carlo U. Liu, Huinan H. Yang, Judith C. Momeni, Kasra Misra, Amit Abdolrahim, Niaz Medvedeva, Julia E. Cai, Wenjun Sehirlioglu, Alp Dizbay-Onat, Melike Mehta, Apurva Graham-Brady, Lori Maruyama, Benji Rajan, Krishna Warner, Jamie H. Taheri, Mitra L. Kalinin, Sergei V. Reeja-Jayan, B. Schwarz, Udo D. Simon, Sindee L. Brown, Craig M. Department of Chemistry and Department of Materials Science & Engineering Texas A & M University College Station United States Pritzker School of Molecular Engineering The University of Chicago Chicago United States Department of Materials Science & Engineering University of California Berkeley Berkeley United States National Center for Electron Microscopy Molecular Foundry Lawrence Berkeley National Laboratory Berkeley United States Center for Nanoscale Materials Argonne National Laboratory Lemont United States Department of Physics University of Washington Seattle United States Department of Materials Science & Engineering The Ohio State University Columbus United States Department of Mechanical Engineering and Mechanics Drexel University Philadelphia United States School of Mechanical Engineering Purdue University West Lafayette United States Department of Chemistry University of Southern California Los Angeles United States Department of Chemistry Stony Brook University The State University of New York Stony Brook United States Department of Chemistry University of Kentucky Lexington United States Department of Physics University of Illinois at Chicago Chicago United States Department of Materials Science & Engineering Northwestern University Evanston Bangladesh Department of Materials Science & Engineering University of Wisconsin–Madison Madison United States Department of Materials Science and Engineering University of Pennsylvania Philadelphia United States Department of Mechanical Engineering and Materials Science Duke University Durham United States Department of Chemistry Creighton University Omaha United States Physical and Computational Sciences Directorate Pacific Northwest National Laboratory Richland United States Department of Materials Science & Engineering University of Michigan–Ann Arbor Ann Arbor United States Department of Physics Illinois Institute of Technology Chicago United States Department of Bioengineering and the Mater

This article was updated to correct Minghao Zhang’s affiliation from "Pritzker School of Molecular engineering, The University of Chicago, Chicago, USA" to "Pritzker School of Molecular engineering, The University of Chicago, Chicago, USA;Argonne National Laboratory, Lemont, USA." Argonne National Laboratory was left off the original publication. © The Author(s) 2025.

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Wireless,multimodal sensors for continuous measurement of pressure,temperature,and hydration of patients in wheelchair

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npj Flexible Electronics 2023年第1期7卷 479-493页

作者： Seokjoo Cho Hyeonseok Han Hyunwoo Park Sung-Uk Lee Jae-Hwan Kim Sung Woo Jeon Mengqiu Wang Raudel Avila Zhaoqian Xi Kabseok Ko Minsu Park Jungyup Lee Myungwoo Choi Je-Sang Lee Weon Gi Min Byeong-Ju Lee Soyeong Lee Jungrak Choi Jimin Gu Jaeho Park Min Seong Kim Junseong Ahn Osman Gul Chankyu Han Gihun Lee Seunghwan Kim Kyuyoung Kim Jeonghyun Kim Chang-Mo Kang Jahyun Koo Sung Soo Kwak Sungbong Kim Dong Yun Choi Seokwoo Jeon Hyung Jin Sung Yong Bae Park Minkyu Je Young Tae Cho Yong Suk Oh Inkyu Park Department of Mechanical Engineering Korea Advanced Institute of Science and TechnologyDaejeon 34141Republic of Korea School of Electrical Engineering Korea Advanced Institute of Science and TechnologyDaejeon 34141Republic of Korea Advanced 3D Printing Technology Development Division Korea Atomic Energy Research InstituteDaejeon 34057Republic of Korea Department of Electrical and Computer Engineering University of Illinois at Urbana-ChampaignUrbanaIL 61801USA State Key Laboratory of Structural Analysis for Industrial Equipment Department of Engineering MechanicsDalian University of TechnologyDalian 116023P.R.China Department of Mechanical Engineering Northwestern UniversityEvanstonIL 60208USA DUT-BSU Joint Institute Dalian University of TechnologyDalian 116023China Ningbo Institute of Dalian University of Technology Ningbo 315016China Department of Electronics Engineering Kangwon National UniversityChuncheon 24341Republic of Korea Querrey-Simpson Institute for Bioelectronics Northwestern UniversityEvanstonIL 60208USA Sibel Health Inc NilesIL 60714USA Department of Materials Science and Engineering KAIST Institute for The Nanocentury(KINC)Korea Advanced Institute of Science and TechnologyDaejeon 34141Republic of Korea Department of Rehabilitation Medicine Gimhae Hansol Rehabilitation&Convalescent HospitalGimhae 50924Republic of Korea Department of planning and development Gimhae Hansol Rehabilitation&Convalescent HospitalGimhae 50924Republic of Korea Department of rehabilitation medicine Pusan national university hospitalBusan 49241Republic of Korea Department of AI Convergence Network Ajou UniversitySuwon 16499Republic of Korea Department of Electronic Convergence Engineering Kwangwoon UniversitySeoul 01897Republic of Korea Korea Photonics Technology Institute Gwangju 61007Republic of Korea School of Biomedical Engineering Korea UniversitySeoul 02841Republic of Korea Interdisciplinary Program in Precision Public Health Korea UniversitySeoul 02841Republic of Korea Center

Individuals who are unable to walk independently spend most of the day in a *** population is at high risk for developing pressure injuries caused by ***,early diagnosis and prevention of these injuries still remain ***,we introduce battery-free,wireless,multimodal sensors and a movable system for continuous measurement of pressure,temperature,and hydration at skin *** device design includes a crack-activated pressure sensor with nanoscale encapsulations for enhanced sensitivity,a temperature sensor for measuring skin temperature,and a galvanic skin response sensor for measuring skin hydration *** movable system enables power harvesting,and data communication to multiple wireless devices mounted at skin-cushion interfaces of wheelchair users over full body *** evaluations and numerical simulations of the devices,together with clinical trials for wheelchair patients,demonstrate the feasibility and stability of the sensor system for preventing pressure injuries caused by sitting.

关键词： injuries modal mounted

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Foundation Models for Atomistic Simulation of Chemistry and Materials

arXiv

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arXiv 2025年

作者： Yuan, Eric C.-Y. Liu, Yunsheng Chen, Junmin Zhong, Peichen Raja, Sanjeev Kreiman, Tobias Vargas, Santiago Xu, Wenbin Head-Gordon, Martin Yang, Chao Blau, Samuel M. Cheng, Bingqing Krishnapriyan, Aditi Head-Gordon, Teresa Kenneth S. Pitzer Theory Center Department of Chemistry United States Department of Chemical and Biomolecular Engineering United States Electrical Engineering and Computer Science United States Bakar Institute of Digital Materials for the Planet University of California BerkeleyCA94720 United States Chemical Sciences Division United States Applied Mathematics and Computational Research Division United States Energy Technologies Area United States National Energy Research Scientific Computing Center Lawrence Berkeley National Laboratory BerkeleyCA94720 United States

Given the power of large language and large vision models, it is of profound and fundamental interest to ask if a foundational model based on data and parameter scaling laws and pre-training strategies is possible for learned simulations of chemistry and materials. The scaling of large and diverse datasets and highly expressive architectures for chemical and materials sciences should result in a foundation model that is more efficient and broadly transferable, robust to out-of-distribution challenges, and easily fine-tuned to a variety of downstream observables, when compared to specific training from scratch on targeted applications in atomistic simulation. In this Perspective we aim to cover the rapidly advancing field of machine learned interatomic potentials (MLIP), and to illustrate a path to create chemistry and materials MLIP foundation models at larger scale. © 2025, CC BY-SA.

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Additive Manufacturing of Ti6Al4V Alloy Through Laser Metal Deposition (LMD): An Elebotative Approach of Process Modelling Via Computational Fluid Dynamics

SSRN

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SSRN 2023年

作者： Rehman, Asif Ur Azher, Kashif Rehman, Aqsa Shah, Mussadiq Mahmood, Muhammed Arif Tüfekci, Celal Sami Salamci, Metin U. ERMAKSAN Bursa Turkey Department of Mechanical Engineering Faculty of Engineering Gazi University Ankara Turkey Additive Manufacturing Technologies Application and Research Center-EKTAM Ankara Turkey Department of Computer Science NFC-IET Punjab Multan60000 Pakistan Advanced Manufacturing Technologies Center of Excellence-URTEMM Ankara Turkey Intelligent Systems Center Missouri University of Science and Technology RollaMO65409 United States

Additive manufacturing (AM) has revolutionized many industries. Laser Melting Deposition (LMD) offers remarkable utility in size and is an effective method in terms of energy efficiency. The interaction of powder with laser before coming in contact with the substrate helps to attain fair melting and deposition. However, there is a problem associated with non-uniformity and accumulation of metallic melt on the edges of the manufactured parts which needs to be understood. Herein, LMD process of Ti6Al4V alloy is presented. The forces defining the melt pool flow have been elaborated. The phenomenon of recoil pressure and Marangoni actions along the single tracks of the melt pool is defined via the computational fluid dynamics (CFD) analysis. The behaviour of the melt pool in conduction mode and to check whether it will form a keyhole region or not. The main factor which influences the melt pool dynamics are found to be surface tension and density differences. Two modes of heat transfer conduction and depression are discussed with the Marangoni actions. Conduction mode is mainly governed by Marangoni actions while the depression mode is by recoil pressure. The stream traces and velocity vectors are observed for single tracks LMD process. A similar Marangoni actions experimental investigation is compared with the phenomenon observed under CFD analysis. The Discrete Element Modelling (DEM) adds value to the study as variable particle diameters are considered which are near to the actual powder size distribution. Moreover, considering the conduction mode flow dynamics to avoid the depression mode and generation of keyhole region in the melt pool will lead to porosity. © 2023, The Authors. All rights reserved.

关键词： Computational fluid dynamics

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Modular Multilevel DC-DC Converter With Inherent Bipolar Operation Capability for Resilient Bipolar MVDC Grids

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CPSS Transactions on Power Electronics and Applications 2022年第1期7卷 37-48页

作者： Shanshan Zhao Yu Chen Shenghui Cui Jingxin Hu State Key Laboratory of Advanced Electromagnetic Engineering and Technology School of Electrical and Electronic Engineering Huazhong University of Science and Technology China Department of Electrical and Computer Engineering Seoul National University Korea Institute for Power Generation and Storage Systems E. ON Energy Research Center RWTH Aachen University Germany

Bipolar medium-voltage dc (MVDC) distribution systems are of great interests nowadays due to its high availability and reliability. A bipolar MVDC grid can be established by the installation of power-balancers or directly by converters with inherent bipolar operation capability to avoid the extra cost and volume. Therefore, this paper proposes a modular multilevel dc-dc converter (MMDC) with inherent bipolar operation capability for the interconnection of bipolar MVDC grids and LVDC girds. Considering that the MMDC is normally only capable of operating with monopole MVDC distribution systems due to the symmetric structure and operation scheme, a center-tapped high-frequency interface transformer is employed on the MV side of the MMDC. Based on the concept of the flux dc-bias cancellation, a dedicated operation method is proposed, whereby the power flows of the two MVDC poles can be regulated independently with a simple control scheme, and no penalty of increased current rating is imposed on the semiconductor devices or the interface transformer compared to the conventional MMDC with monopole operation. Additionally, the MMDC can realize single-pole operation in case one pole is faulty and deliver at least 50% of the rated power capacity, which significantly enhance the reliability and availability of the power delivery. The validity of the proposed bipolar operation scheme of the MMDC has been verified by both simulations and experiments with a down-scale prototype.

关键词： Multilevel converters Semiconductor devices Prototypes DC-DC power converters Transformers Valves Power electronics

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Clinically Interpretable Machine Learning Models for Early Prediction of Mortality in Older Patients with Multiple Organ Dysfunction Syndrome: An International Multicenter Retrospective Study

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Journals of Gerontology - Series A Biological sciences and Medical sciences 2023年第4期78卷 718-726页

作者： Liu, Xiaoli DuMontier, Clark Hu, Pan Liu, Chao Yeung, Wesley Mao, Zhi Ho, Vanda Thoral, Patrick J. Kuo, Po-Chih Hu, Jie Li, Deyu Cao, Desen Mark, Roger G. Zhou, FeiHu Zhang, Zhengbo Celi, Leo Anthony Key Laboratory for Biomechanics and Mechanobiology of Ministry of Education Beijing Advanced Innovation Center for Biomedical Engineering School of Biological Science and Medical Engineering Beihang University Beijing China Laboratory for Computational Physiology Institute for Medical Engineering and Science Massachusetts Institute of Technology Cambridge MA United States Center for Artificial Intelligence in Medicine General Hospital of PLA Beijing China New England Geriatric Research Education and Clinical Center VA Boston Healthcare System Boston MA United States Division of Aging Brigham and Women's Hospital Boston MA United States Department of Anesthesiology 920 Hospital of Joint Logistic Support Force of Chinese PLA Kunming Yunnan China Department of Critical Care Medicine First Medical Center General Hospital of PLA Beijing China Department of Medicine National University Hospital Singapore Division of Geriatric Medicine Department of Medicine National University Hospital Singapore Department of Intensive Care Medicine Amsterdam Netherlands Department of Computer Science National Tsing Hua University Hsinchu Taiwan Department of Biomedical Engineering General Hospital of PLA Beijing China Elderly Center General Hospital of PLA Beijing China Department of Medicine Beth Israel Deaconess Medical Center Boston MA United States Department of Biostatistics Harvard T.H. Chan School of Public Health Boston MA United States

BACKGROUND: Multiple organ dysfunction syndrome (MODS) is associated with a high risk of mortality among older patients. Current severity scores are limited in their ability to assist clinicians with triage and management decisions. We aim to develop mortality prediction models for older patients with MODS admitted to the ICU. METHODS: The study analyzed older patients from 197 hospitals in the United States and 1 hospital in the Netherlands. The cohort was divided into the young-old (65-80 years) and old-old (≥80 years), which were separately used to develop and evaluate models including internal, external, and temporal validation. Demographic characteristics, comorbidities, vital signs, laboratory measurements, and treatments were used as predictors. We used the XGBoost algorithm to train models, and the SHapley Additive exPlanations (SHAP) method to interpret predictions. RESULTS: Thirty-four thousand four hundred and ninety-seven young-old (11.3% mortality) and 21 330 old-old (15.7% mortality) patients were analyzed. Discrimination AUROC of internal validation models in 9 046 U.S. patients was as follows: 0.87 and 0.82, respectively;discrimination of external validation models in 1 905 EUR patients was as follows: 0.86 and 0.85, respectively;and discrimination of temporal validation models in 8 690 U.S. patients: 0.85 and 0.78, respectively. These models outperformed standard clinical scores like Sequential Organ Failure Assessment and Acute Physiology Score III. The Glasgow Coma Scale, Charlson Comorbidity Index, and Code Status emerged as top predictors of mortality. CONCLUSIONS: Our models integrate data spanning physiologic and geriatric-relevant variables that outperform existing scores used in older adults with MODS, which represents a proof of concept of how machine learning can streamline data analysis for busy ICU clinicians to potentially optimize prognostication and decision making. © The Author(s) 2022. Published by Oxford University Press on behalf

关键词： International multicenter Interpretable models Machine learning Mortality Multiple organ dysfunction syndrome

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Label Informed Contrastive Pretraining for Node Importance Estimation on Knowledge Graphs

arXiv

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arXiv 2024年

作者： Zhang, Tianyu Hou, Chengbin Jiang, Rui Zhang, Xuegong Zhou, Chenghu Tang, Ke Lv, Hairong The Ministry of Education Key Laboratory of Bioinformatics Bioinformatics Division Beijing National Research Center for Information Science and Technology Department of Automation Tsinghua University Beijing100084 China The School of Computer Science and Engineering Fuyao Institute of Technology Fuzhou350109 China The State Key Laboratory of Resources and Environmental Information Systems Institute of Geographic Sciences and Natural Resources Research Chinese Academy of Sciences Beijing100101 China The Department of Computer Science and Engineering Southern University of Science and Technology Shenzhen518055 China The Fuzhou Institute of Data Technology Fuzhou350200 China

Node Importance Estimation (NIE) is a task of inferring importance scores of the nodes in a graph. Due to the availability of richer data and knowledge, recent research interests of NIE have been dedicating to knowledge graphs for predicting future or missing node importance scores. Existing state-of-the-art NIE methods train the model by available labels, and they consider every interested node equally before training. However, the nodes with higher importance often require or receive more attention in real-world scenarios, e.g., people may care more about the movies or webpages with higher importance. To this end, we introduce Label Informed ContrAstive Pretraining (LICAP) to the NIE problem for being better aware of the nodes with high importance scores. Specifically, LICAP is a novel type of contrastive learning framework that aims to fully utilize the continuous labels to generate contrastive samples for pretraining embeddings. Considering the NIE problem, LICAP adopts a novel sampling strategy called top nodes preferred hierarchical sampling to first group all interested nodes into a top bin and a non-top bin based on node importance scores, and then divide the nodes within top bin into several finer bins also based on the scores. The contrastive samples are generated from those bins, and are then used to pretrain node embeddings of knowledge graphs via a newly proposed Predicate-aware Graph Attention Networks (PreGAT), so as to better separate the top nodes from non-top nodes, and distinguish the top nodes within top bin by keeping the relative order among finer bins. Extensive experiments demonstrate that the LICAP pretrained embeddings can further boost the performance of existing NIE methods and achieve the new state-of-the-art performance regarding both regression and ranking metrics. The source code for reproducibility is available at https://***/zhangtia16/LICAP Copyright © 2024, The Authors. All rights reserved.

关键词： Knowledge graph

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RETRACTION: Luminescent solar concentrator efficiency enhanced via nearly lossless propagation pathways

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NATURE PHOTONICS 2024年第9期18卷 998-998页

作者： Park, Kyoungwon Yi, Jeongmin Yoon, Suk-Young Park, Seong Min Kim, Jiyong Shin, Hyun-Beom Biswas, Swarup Yoo, Gang Yeol Moon, Sang-Hwa Kim, Jiwan Oh, Min Suk Wedel, Armin Jeong, Sohee Kim, Hyeok Oh, Soong Ju Kang, Ho Kwan Yang, Heesun Han, Chul Jong Display Research Center Korea Electronics Technology Institute Seongnam-si Republic of Korea Department of Materials Science and Engineering Korea University Seoul Republic of Korea Department of Materials Science and Engineering Hongik University Seoul Republic of Korea Functional Materials and Devices Fraunhofer Institute for Applied Polymer Research Potsdam Germany Device Technology Division Korea Advanced Nano Fab Center Suwon-si Republic of Korea School of Electrical and Computer Engineering Center for Smart Sensor System of Seoul (CS4) University of Seoul Seoul Republic of Korea Department of Advanced Materials Engineering Kyonggi University Suwon-si Republic of Korea Department of Energy Science Sungkyunkwan Institute of Energy Science and Technology (SIEST) Artificial Atom and Quantum Materials Center Sungkyunkwan University (SKKU) Suwon Republic of Korea

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