The number of international benchmarking competitions is steadily increasing in various fields of machine learning (ML) research and practice. So far, however, little is known about the common practice as well as bott...
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The cell is arguably the most fundamental unit of life and is central to understanding biology. Accurate modeling of cells is important for this understanding as well as for determining the root causes of disease. Rec...
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Intelligent decision-making (IDM) is a cornerstone of artificial intelligence (AI) designed to automate or augment decision processes. Modern IDM paradigms integrate advanced frameworks to enable intelligent agents to...
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In biometrics, face recognition methods are achieving momentum with recent progress in the computer vision(CV). Face recognition is widely used in the identification of an individual's identity. Unfortunately, in ...
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In biometrics, face recognition methods are achieving momentum with recent progress in the computer vision(CV). Face recognition is widely used in the identification of an individual's identity. Unfortunately, in recent research work has revealed this face biometrics system is unprotected to spoofing attacks using by very low price instrument such as printed 2D photos attack, 3D masking attack and taking videos using smart devices (reply attack). Therefore, a Liveness Attack Detection (LAD) approach is needed to improve the high-quality security of face recognition system. Most of the earlier worked LAD methods for face anti-spoofing methods have highlight on using the handcrafted features, which are developed by expert knowledge of researcher. As example Gabor filter, Histogram of Oriented Gradients, local ternary pattern, and the Local Binary Pattern. Because of that, the extracted features consider limited factors of the problem, yielding a capture accuracy that is very low and changes with the point of presentation in attack face images. The deep learning method has developed in the computer vision research community, which is proven to be suitable for automatically training. In this article, we approach to mix or combine the handcrafted features and deep neural network features to design the discriminant face spoofing detection. The handcrafted features were based on LBP analysis. We examine the features information from the brightness and the chrominance channels using LBP descriptor. In deep features, we present an approach based on pre-trained convolutional neural network VGG-16 model using static features to recognize video and printed(2D) photo attacks. By attaching this two types of image features on our dataset and public databases, we get good results to identify real and attack images feature, called hybrid features, which has better discrimination ability to understand spoofing image feature.
Analysis of an individual's immunoglobulin or T cell receptor gene repertoire can provide important insights into immune function. High-quality analysis of adaptive immune receptor repertoire sequencing data depen...
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Analysis of an individual's immunoglobulin or T cell receptor gene repertoire can provide important insights into immune function. High-quality analysis of adaptive immune receptor repertoire sequencing data depends upon accurate and relatively complete germline sets, but current sets are known to be incomplete. Established processes for the review and systematic naming of receptor germline genes and alleles require specific evidence and data types, but the discovery landscape is rapidly changing. To exploit the potential of emerging data, and to provide the field with improved state-of-the-art germline sets, an intermediate approach is needed that will allow the rapid publication of consolidated sets derived from these emerging sources. These sets must use a consistent naming scheme and allow refinement and consolidation into genes as new information emerges. Name changes should be minimised, but, where changes occur, the naming history of a sequence must be traceable. Here we outline the current issues and opportunities for the curation of germline IG/TR genes and present a forward-looking data model for building out more robust germline sets that can dovetail with current established processes. We describe interoperability standards for germline sets, and an approach to transparency based on principles of findability, accessibility, interoperability, and reusability.
Science is and always has been based on data, but the terms ‘data-centric’ and the ‘4th paradigm’ of materials research indicate a radical change in how information is retrieved, handled and research is performed....
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Background: The COVID-19 pandemic highlighted gaps in health surveillance systems, disease prevention, and treatment globally. Among the many factors that might have led to these gaps is the issue of the financing of ...
Background: The COVID-19 pandemic highlighted gaps in health surveillance systems, disease prevention, and treatment globally. Among the many factors that might have led to these gaps is the issue of the financing of national health systems, especially in low-income and middle-income countries (LMICs), as well as a robust global system for pandemic preparedness. We aimed to provide a comparative assessment of global health spending at the onset of the pandemic;characterise the amount of development assistance for pandemic preparedness and response disbursed in the first 2 years of the COVID-19 pandemic;and examine expectations for future health spending and put into context the expected need for investment in pandemic preparedness. Methods: In this analysis of global health spending between 1990 and 2021, and prediction from 2021 to 2026, we estimated four sources of health spending: development assistance for health (DAH), government spending, out-of-pocket spending, and prepaid private spending across 204 countries and territories. We used the Organisation for Economic Co-operation and Development (OECD)'s Creditor Reporting System (CRS) and the WHO Global Health Expenditure Database (GHED) to estimate spending. We estimated development assistance for general health, COVID-19 response, and pandemic preparedness and response using a keyword search. Health spending estimates were combined with estimates of resources needed for pandemic prevention and preparedness to analyse future health spending patterns, relative to need. Findings: In 2019, at the onset of the COVID-19 pandemic, US$9·2 trillion (95% uncertainty interval [UI] 9·1–9·3) was spent on health worldwide. We found great disparities in the amount of resources devoted to health, with high-income countries spending $7·3 trillion (95% UI 7·2–7·4) in 2019;293·7 times the $24·8 billion (95% UI 24·3–25·3) spent by low-income countries in 2019. That same year, $43·1 billion in development assistance was provided
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