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2017 IEEE International Conference on robotics and automation, ICRA 2017

作者： Guo, Dejun Wang, Hesheng Chen, Weidong Liu, Ming Xia, Zeyang Leang, Kam K. Lab University of Utah Robotics Center Salt Lake CityUT84112 United States Department of Automation Shanghai Jiao Tong University Shanghai200240 China Department of Electronics and Computer Engineering Hong Kong University of Science and Technology Hong Kong Hong Kong Institute of Biomedical and Health Engineering Key Laboratory of Human-Machine Intelligence-Synergy Systems Shenzhen Institutes of Advanced Technology Chinese Academy of Sciences Shenzhen China

ISBN: (纸本)9781509046331

This paper studies the problem of image-based leader-follower formation control for mobile robots, where the controller is designed independently of the leader's motion. An adaptive control scheme, which is suitable for both omnidirectional and perspective cameras, is proposed. The proposed approach avoids the need for accurate calibration of the extrinsic parameters of the omnidirectional camera as well as the intrinsic and extrinsic parameters of perspective camera. Additionally, the coefficients of the plane where the feature point moves relative to the camera frame can be uncertain. These uncertain constant parameters are estimated using an adaptive estimator. Uniform Semi-global Practical Asymptotic Stability (USPAS) of the system is shown using the Lyapunov approach. Experimental results are presented to demonstrate the effectiveness of the proposed control scheme. © 2017 IEEE.

关键词： Mobile robots

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Automatic metal drum opening-sealing device prototype for nuclear power plant

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Revista Tecnica de la Facultad de Ingenieria Universidad del Zulia 2016年第6期39卷 264-275页

作者： Liu, Sibang Ge, Shuzhi Sam Zhao, Qian Huang, Gang Su, Zhe School of Automation Engineering University of Electronic Science and Technology of China ChengduSichuan611731 China Center for Robotics University of Electronic Science and Technology of China ChengduSichuan611731 China Department of Electrical and Computer Engineering National University of Singapore Singapore Singapore Centre for Robotics University of Electronic Science and Technology of China China

Automatic metal drum opening-sealing device is the key device of the low and intermediate level radioactive wastes treatment line for the nuclear power plant, which is used to open and seal the metal drum filled with radioactive wastes automatically. This paper firstly analyzes the key technologies of the metal drum opening-sealing device which include the technology of metal drum positioning, drum trip bolt and bolt hole positioning, drum cover depositing and bolt tightening shaft torque controlling. Then, based on the modular design method, a device prototype was designed and made and tests were carried out based on the prototype. The test results verified the design rationality and high operation efficiency of the prototype. © 2016, Revista Tecnica de la Facultad de Ingeniera. All rights reserved.

关键词： Bolt tightening

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Adaptive control for an uncertain robotic manipulator with input saturations

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Control Theory and Technology 2016年第2期14卷 113-121页

作者： Trong-Toan TRAN Shuzhi Sam GE Wei HE Center for Robotics and School of Automation Engineering University of Electronic Science and Technology of China (UESTC) Chengdu Sichuan 611731 China Department of Electrical and Computer Engineering National University of Singapore Singapore 117576 Faculty of Electronic Technology Industrial University of rio Chi Minh City Ho Chi Minh City Vietnam School of Automation and Electrical Engineering University of Science and Technology Beijing Beijing 100083 China

In this paper, we address the control problem of an uncertain robotic manipulator with input saturations, unknown input scalings and disturbances. For this purpose, a model reference adaptive control like （MRAC-like） is used to handle the input saturations. The model reference is input to state stable （ISS） and driven by the errors between the required control signals and input saturations. The uncertain parameters are dealt with by using linear-in-the-parameters property of robotic dynamics, while unknown input scalings and disturbances are handled by non-regressor based approach. Our design ensures that all the signals in the closed-loop system are bounded, and the tracking error converges to the compact set which depends on the predetermined bounds of the control inputs. Simulation on a planar elbow manipulator with two joints is provided to illustrate the effectiveness of the proposed controller.

关键词： Robotic manipulator adaptive control uncertain parameter input saturation trajectory tracking

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A novel extended potential field controller for use on aerial robots

A novel extended potential field controller for use on aeria...

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2016 IEEE International Conference on automation science and engineering, CASE 2016

作者： Woods, Alexander C. Lay, Hung M. Ha, Quang P. Advanced Robotics and Automation Laboratory Department of Computer Science and Engineering University of Nevada RenoNV89557 United States School of Electrical Mechanical and Mechatronic Systems University of Technology Sydney Australia

ISBN: (纸本)9781509024094

Unmanned Aerial Vehicles (UAV), commonly known as drones, have many potential uses in real world applications. Drones require advanced planning and navigation algorithms to enable them to safely move through and interact with the world around them. This paper presents an extended potential field controller (ePFC) which enables an aerial robot, or drone, to safely track a dynamic target location while simultaneously avoiding any obstacles in its path. The ePFC outperforms a traditional potential field controller (PFC) with smoother tracking paths and shorter settling times. The proposed ePFC's stability is evaluated by Lyapunov approach, and its performance is simulated in a Matlab environment. Finally, the controller is implemented on an experimental platform in a laboratory environment which demonstrates the effectiveness of the controller. © 2016 IEEE.

关键词： Controllers

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NTIRE 2018 Challenge on Single Image Super-Resolution: Methods and Results

NTIRE 2018 Challenge on Single Image Super-Resolution: Metho...

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IEEE computer Society Conference on computer Vision and Pattern Recognition Workshops (CVPRW)

作者： Radu Timofte Shuhang Gu Jiqing Wu Luc Van Gool Lei Zhang Ming-Hsuan Yang Muhammad Haris Greg Shakhnarovich Norimichi Ukita Shijia Hu Yijie Bei Zheng Hui Xiao Jiang Yanan Gu Jie Liu Yifan Wang Federico Perazzi Brian McWilliams Alexander Sorkine-Hornung Olga Sorkine-Hornung Christopher Schroers Jiahui Yu Yuchen Fan Jianchao Yang Ning Xu Zhaowen Wang Xinchao Wang Thomas S. Huang Xintao Wang Ke Yu Tak-Wai Hui Chao Dong Liang Lin Chen Change Loy Dongwon Park Kwanyoung Kim Se Young Chun Kai Zhang Pengjv Liu Wangmeng Zuo Shi Guo Jiye Liu Jinchang Xu Yijiao Liu Fengye Xiong Yuan Dong Hongliang Bai Alexandru Damian Nikhil Ravi Sachit Menon Cynthia Rudin Junghoon Seo Taegyun Jeon Jamyoung Koo Seunghyun Jeon Soo Ye Kim Jae-Seok Choi Sehwan Ki Soomin Seo Hyeonjun Sim Saehun Kim Munchurl Kim Rong Chen Kun Zeng Jinkang Guo Yanyun Qu Cuihua Li Namhyuk Ahn Byungkon Kang Kyung-Ah Sohn Yuan Yuan Jiawei Zhang Jiahao Pang Xiangyu Xu Yan Zhao Wei Deng Sibt Ul Hussain Muneeb Aadil Rafia Rahim Xiaowang Cai Fang Huang Yueshu Xu Pablo Navarrete Michelini Dan Zhu Hanwen Liu Jun-Hyuk Kim Jong-Seok Lee Yiwen Huang Ming Qiu Liting Jing Jiehang Zeng Ying Wang Manoj Sharma Rudrabha Mukhopadhyay Avinash Upadhyay Sriharsha Koundinya Ankit Shukla Santanu Chaudhury Zhe Zhang Yu Hen Hu Lingzhi Fu ETH Zurich Zurich Switzerland Merantix Germany NTIRE Eidgenossische Technische Hochschule Zurich Zurich ZH CH ESAT KU Leuven Belgium University of California at Merced CA USA Toyota Technological Institute TTI-Chicago Chicago US Duke University US School of Electronic Engineering Xidian University China Disney Research Facebook Oculus University of Illinois at Urbana-Champaign Illinois US Snap Inc. Snap Inc. Adobe Research Stevens Institute of Technology US University of Illinois at Urbana-Champaign US The Chinese University of Hong Kong Hong Kong China SenseTime Research School of Electrical and Computer Engineering National Institute of Science and Technolog Korea School of Electrical and Computer Engineering National Institute of Science and Technology Korea School of Computer Science and Technology Harbin Institute of Technology Harbin China Beijing University of Posts and Telecommunications China Beijing Faceall Technology Co. Ltd China Satrec Initiative R&D Center Korea Advanced Institute of Science and Technology Korea Xiamen University China Xiamen Universi China Ajou University Korea Electrical and Computer Engineering University of Alberta Canada Fuzhou University China National University of Computer & Emerging Sciences Islamabad Pakistan BOE Technology Group Co. Ltd. Yonsei University Korea Wenhua College China Software School Xiamen University China CSIR-CEERI India University of Wisconsin-Madison Madison Wisconsin US Institute of Integrated Automation School of Electronic and Information Engineering Xian Jiaotong University China

ISBN: (数字)9781538661000

ISBN: (纸本)9781538661017

This paper reviews the 2nd NTIRE challenge on single image super-resolution (restoration of rich details in a low resolution image) with focus on proposed solutions and results. The challenge had 4 tracks. Track 1 employed the standard bicubic downscaling setup, while Tracks 2, 3 and 4 had realistic unknown downgrading operators simulating camera image acquisition pipeline. The operators were learnable through provided pairs of low and high resolution train images. The tracks had 145, 114, 101, and 113 registered participants, resp., and 31 teams competed in the final testing phase. They gauge the state-of-the-art in single image super-resolution.

关键词： Image resolution Degradation Training Runtime computer architecture Testing Tracking

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The ultra-high-energy event KM3-230213A within the global neutrino landscape

arXiv

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arXiv 2025年

作者： Adriani, O. Aiello, S. Albert, A. Alhebsi, A.R. Alshamsi, M. Garre, S. Alves Ambrosone, A. Ameli, F. Andre, M. Aphecetche, L. Ardid, M. Ardid, S. Argüelles, C. Aublin, J. Badaracco, F. Bailly-Salins, L. Bardačová, Z. Baret, B. Bariego-Quintana, A. Becherini, Y. Bendahman, M. Gualandi, F. Benfenati Benhassi, M. Bennani, M. Benoit, D.M. Berbee, E. Berti, E. Bertin, V. Betti, P. Biagi, S. Boettcher, M. Bonanno, D. Bottai, S. Bouasla, A.B. Boumaaza, J. Bouta, M. Bouwhuis, M. Bozza, C. Bozza, R.M. Brânzaş, H. Bretaudeau, F. Breuhaus, M. Bruijn, R. Brunner, J. Bruno, R. Buis, E. Buompane, R. Busto, J. Caiffi, B. Calvo, D. Capone, A. Carenini, F. Carretero, V. Cartraud, T. Castaldi, P. Cecchini, V. Celli, S. Cerisy, L. Chabab, M. Chen, A. Cherubini, S. Chiarusi, T. Circella, M. Clark, R. Cocimano, R. Coelho, J.A.B. Coleiro, A. Condorelli, A. Coniglione, R. Coyle, P. Creusot, A. Cuttone, G. Dallier, R. De Benedittis, A. De Wasseige, G. Decoene, V. Deguire, P. Del Rosso, I. Di Mauro, L.S. Di Palma, I. Díaz, A.F. Diego-Tortosa, D. Distefano, C. Domi, A. Donzaud, C. Dornic, D. Drakopoulou, E. Drouhin, D. Ducoin, J.-G. Duverne, P. Dvornický, R. Eberl, T. Eckerová, E. Eddymaoui, A. van Eeden, T. Eff, M. van Eijk, D. El Bojaddaini, I. El Hedri, S. El Mentawi, S. Ellajosyula, V. Enzenhöfer, A. Ferrara, G. Filipović, M.D. Filippini, F. Franciotti, D. Fusco, L.A. Gal, T. Méndez, J. García Soto, A. Garcia Oliver, C. Gatius Geißelbrecht, N. Genton, E. Ghaddari, H. Gialanella, L. Gibson, B.K. Giorgio, E. Goos, I. Goswami, P. Gozzini, S.R. Gracia, R. Guidi, C. Guillon, B. Gutiérrez, M. Haack, C. van Haren, H. Heijboer, A. Hennig, L. Hernández-Rey, J.J. Idrissi, A. Ibnsalih, W. Idrissi Illuminati, G. Janik, O. Joly, D. de Jong, M. de Jong, P. Jung, B.J. Kalaczyński, P. Kamp, N. Keegans, J. Kikvadze, V. Kistauri, G. Kopper, C. Kouchner, A. Kovalev, Y.Y. Krupa, L. Kueviakoe, V. Kulikovskiy, V. Kvatadze, R. Labalme, M. Lahmann, R. INFN Sezione di Firenze via Sansone 1 Sesto Fiorentino50019 Italy Università di Firenze Dipartimento di Fisica e Astronomia via Sansone 1 Sesto Fiorentino50019 Italy Via Santa Sofia 64 Catania95123 Italy Université de Strasbourg CNRS IPHC UMR 7178 StrasbourgF-67000 France Université de Haute Alsace rue des Frères Lumière Mulhouse68093 Cedex France Khalifa University of Science and Technology Department of Physics PO Box 127788 Abu Dhabi United Arab Emirates Aix Marseille Univ CNRS IN2P3 CPPM Marseille France c/Catedrático José Beltrán 2 Valencia Paterna46980 Spain Università di Napoli "Federico II" Dip. Scienze Fisiche "E. Pancini" Complesso Universitario di Monte S. Angelo Via Cintia ed. G Napoli80126 Italy INFN Sezione di Napoli Complesso Universitario di Monte S. Angelo Via Cintia ed. G Napoli80126 Italy INFN Sezione di Roma Piazzale Aldo Moro 2 Roma00185 Italy Universitat Politècnica de Catalunya Laboratori d’Aplicacions Bioacústiques Centre Tecnològic de Vilanova i la Geltrú Avda. Rambla Exposició s/n Vilanova i la Geltrú08800 Spain Subatech IMT Atlantique IN2P3-CNRS Nantes Université 4 rue Alfred Kastler - La Chantrerie BP Nantes20722 44307 France Universitat Politècnica de València Instituto de Investigación para la Gestión Integrada de las Zonas Costeras C/ Paranimf 1 Gandia46730 Spain Harvard University Department of Physics Laboratory for Particle Physics and Cosmology Lyman Laboratory 17 Oxford St. CambridgeMA02138 United States Université Paris Cité CNRS Astroparticule et Cosmologie ParisF-75013 France INFN Sezione di Genova Via Dodecaneso 33 Genova16146 Italy Università di Genova Via Dodecaneso 33 Genova16146 Italy LPC CAEN Normandie Univ ENSICAEN UNICAEN CNRS IN2P3 6 boulevard Maréchal Juin Caen14050 France Comenius University in Bratislava Department of Nuclear Physics and Biophysics Mlynska dolina F1 Bratislava842 48 Slovakia Czech Technical University in Prague Institute of Experimen

On February 13th, 2023, the KM3NeT/ARCA telescope detected a neutrino candidate with an estimated energy in the hundreds of PeVs. In this article, the observation of this ultra-high-energy neutrino is discussed in light of null observations above tens of PeV from the IceCube and Pierre Auger observatories. Performing a joint fit of all experiments under the assumption of an isotropic E−2 flux, the best-fit single-flavour flux normalisation is E2Φ1fν+ν¯ = 7.5 × 10−10 GeVcm−2s−1sr−1 in the 90% energy range of the KM3NeT event. Furthermore, the ultra-high-energy data are then fit together with the IceCube measurements at lower energies, either with a single power law or with a broken power law, allowing for the presence of a new component in the spectrum. The joint fit including non-observations by other experiments in the ultra-high-energy region shows a slight preference for a break in the PeV regime if the "High-Energy Starting Events" sample is included, and no such preference for the other two IceCube samples investigated. A stronger preference for a break appears if only the KM3NeT data is considered in the ultra-high-energy region, though the flux resulting from such a fit would be inconsistent with null observations from IceCube and Pierre Auger. In all cases, the observed tension between KM3NeT and other datasets is of the order of 2.5σ − 3σ, and increased statistics are required to resolve this apparent tension and better characterise the neutrino landscape at ultra-high energies. Copyright © 2025, The Authors. All rights reserved.

关键词： Neutrons

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Cooperative control of a nonuniform gantry crane with constrained tension

Cooperative control of a nonuniform gantry crane with constr...

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作者： He, Wei Ge, Shuzhi Sam School of Automation and Electrical Engineering University of Science and Technology Beijing Beijing100083 China Department of Electrical and Computer Engineering National University of Singapore Singapore117576 Singapore Center for Robotics University of Electronic Science and Technology of China Chengdu611731 China

In this paper, the control problem is addressed for a hybrid PDE-ODE system that describes a nonuniform gantry crane system with constrained tension. A bottom payload hangs from the top gantry by connecting a flexible cable. The flexible cable is nonuniform due to the spatiotemporally varying tension applied to the system. The control objectives are: (i) to position the payload to the desired setpoint, (ii) to regulate the transverse deflection of the flexible cable, and (iii) to keep the tension values remaining in the constrained space. Cooperative control laws are proposed and the integral-barrier Lyapunov functions are employed for stability analysis of the closed-loop system. Adaption laws are developed for handling parametric uncertainties. The bounded stability is guaranteed through rigorous analysis without any simplification of the dynamics. In the end, numerical simulations are displayed to illustrate the performance of the proposed cooperative control. © 2016 Elsevier Ltd. All rights reserved.

关键词： Flexible structures

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Optoelectronic Devices: Thin Metallic Heat Sink for Interfacial Thermal Management in Biointegrated Optoelectronic Devices (Adv. Mater. Technol. 11/2018)

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advanced Materials Technologies 2018年第11期3卷

作者： Han Hee Jung Juwon Song Shuang Nie Han Na Jung Min Seok Kim Jae-Woong Jeong Young Min Song Jizhou Song Kyung-In Jang Department of Robotics Engineering Department of Information and Communication Engineering Brain Engineering Convergence Center Daegu Gyeongbuk Institute of Science and Technology Daegu 49288 Republic of Korea Department of Engineering Mechanics Soft Matter Research Center and Key Laboratory of Soft Machines and Smart Devices of Zhejiang Province Zhejiang University Hangzhou 310027 China School of Electrical Engineering and Computer Science Gwangju Institute of Science and Technology 123 Cheomdan-gwagiro Buk-gu Gwangju 61005 Republic of Korea School of Electrical Engineering Korea Advanced Institute of Science and Technology Daejeon 34141 Republic of Korea

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On the Potential Galactic Origin of the Ultra-High-Energy Event KM3-230213A

arXiv

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arXiv 2025年

作者： Adriani, O. Aiello, S. Albert, A. Alhebsi, A.R. Alshamsi, M. Garre, S. Alves Ambrosone, A. Ameli, F. Andre, M. Aphecetche, L. Ardid, M. Ardid, S. Aublin, J. Badaracco, F. Bailly-Salins, L. Bardačová, Z. Baret, B. Bariego-Quintana, A. Becherini, Y. Bendahman, M. Gualandi, F. Benfenati Benhassi, M. Bennani, M. Benoit, D.M. Berbee, E. Berti, E. Bertin, V. Betti, P. Biagi, S. Boettcher, M. Bonanno, D. Bottai, S. Bouasla, A.B. Boumaaza, J. Bouta, M. Bouwhuis, M. Bozza, C. Bozza, R.M. Brânzaş, H. Bretaudeau, F. Breuhaus, M. Bruijn, R. Brunner, J. Bruno, R. Buis, E. Buompane, R. Busto, J. Caiffi, B. Calvo, D. Capone, A. Carenini, F. Carretero, V. Cartraud, T. Castaldi, P. Cecchini, V. Celli, S. Cerisy, L. Chabab, M. Chen, A. Cherubini, S. Chiarusi, T. Circella, M. Clark, R. Cocimano, R. Coelho, J.A.B. Coleiro, A. Condorelli, A. Coniglione, R. Coyle, P. Creusot, A. Cuttone, G. Dallier, R. De Benedittis, A. De Wasseige, G. Decoene, V. Deguire, P. Del Rosso, I. Di Mauro, L.S. Di Palma, I. Díaz, A.F. Diego-Tortosa, D. Distefano, C. Domi, A. Donzaud, C. Dornic, D. Drakopoulou, E. Drouhin, D. Ducoin, J.-G. Duverne, P. Dvornický, R. Eberl, T. Eckerová, E. Eddymaoui, A. van Eeden, T. Eff, M. van Eijk, D. Bojaddaini, I.El. Hedri, S.El. Mentawi, S.El. Ellajosyula, V. Enzenhöfer, A. Ferrara, G. Filipović, M.D. Filippini, F. Franciotti, D. Fusco, L.A. Gal, T. Méndez, J. García Soto, A. Garcia Oliver, C. Gatius Geißelbrecht, N. Genton, E. Ghaddari, H. Gialanella, L. Gibson, B.K. Giorgio, E. Goos, I. Goswami, P. Gozzini, S.R. Gracia, R. Guidi, C. Guillon, B. Gutiérrez, M. Haack, C. van Haren, H. Heijboer, A. Hennig, L. Hernández-Rey, J.J. Idrissi, A. Ibnsalih, W. Idrissi Illuminati, G. Janik, O. Joly, D. de Jong, M. de Jong, P. Jung, B.J. Kalaczyński, P. Keegans, J. Kikvadze, V. Kistauri, G. Kopper, C. Kouchner, A. Kovalev, Y.Y. Krupa, L. Kueviakoe, V. Kulikovskiy, V. Kvatadze, R. Labalme, M. Lahmann, R. INFN Sezione di Firenze via Sansone 1 Sesto Fiorentino50019 Italy Università di Firenze Dipartimento di Fisica e Astronomia via Sansone 1 Sesto Fiorentino50019 Italy Via Santa Sofia 64 Catania95123 Italy Université de Strasbourg CNRS IPHC UMR 7178 StrasbourgF-67000 France Université de Haute Alsace rue des Frères Lumière Mulhouse68093Cedex France Khalifa University of Science and Technology Department of Physics PO Box 127788 Abu Dhabi United Arab Emirates Aix Marseille Univ CNRS IN2P3 CPPM Marseille France c/Catedrático José Beltrán 2 Valencia Paterna46980 Spain Università di Napoli "Federico II" Dip. Scienze Fisiche "E. Pancini" Complesso Universitario di Monte S. Angelo Via Cintia ed. G Napoli80126 Italy INFN Sezione di Napoli Complesso Universitario di Monte S. Angelo Via Cintia ed. G Napoli80126 Italy INFN Sezione di Roma Piazzale Aldo Moro 2 Roma00185 Italy Universitat Politècnica de Catalunya Laboratori d’Aplicacions Bioacústiques Centre Tecnològic de Vilanova i la Geltrú Avda. Rambla Exposició s/n Vilanova i la Geltrú08800 Spain Subatech IMT Atlantique IN2P3 CNRS Nantes Université 4 rue Alfred Kastler - La Chantrerie BP Nantes20722 44307 France Universitat Politècnica de València Instituto de Investigación para la Gestión Integrada de las Zonas Costeras C/ Paranimf 1 Gandia46730 Spain Université Paris Cité CNRS Astroparticule et Cosmologie ParisF-75013 France INFN Sezione di Genova Via Dodecaneso 33 Genova16146 Italy Università di Genova Via Dodecaneso 33 Genova16146 Italy LPC CAEN Normandie Univ ENSICAEN UNICAEN CNRS IN2P3 6 boulevard Maréchal Juin Caen14050 France Comenius University in Bratislava Department of Nuclear Physics and Biophysics Mlynska dolina F1 Bratislava842 48 Slovakia Czech Technical University in Prague Institute of Experimental and Applied Physics Husova 240/5 Prague110 00 Czech Republic Università di Bologna Dipartimento di Fisica e Astronomia v.le C. Berti-Pichat 6/2

The KM3NeT observatory detected the most energetic neutrino candidate ever observed, with an energy between 72 PeV and 2.6 EeV at the 90 % confidence level. The observed neutrino is likely of cosmic origin. In this article, it is investigated if the neutrino could have been produced within the Milky Way. Considering the low fluxes of the Galactic diffuse emission at these energies, the lack of a nearby potential Galactic particle accelerator in the direction of the event and the difficulty to accelerate particles to such high energies in Galactic systems, we conclude that if the event is indeed cosmic, it is most likely of extragalactic origin. Copyright © 2025, The Authors. All rights reserved.

关键词： Neutrons

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Identifying the best machine learning algorithms for brain tumor segmentation, progression assessment, and overall survival prediction in the BRATS challenge

arXiv

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arXiv 2018年

作者： Bakas, Spyridon Reyes, Mauricio Jakab, Andras Bauer, Stefan Rempfler, Markus Crimi, Alessandro Shinohara, Russell Takeshi Berger, Christoph Ha, Sung Min Rozycki, Martin Prastawa, Marcel Alberts, Esther Lipkova, Jana Freymann, John Kirby, Justin Bilello, Michel Fathallah-Shaykh, Hassan M. Wiest, Roland Kirschke, Jan Wiestler, Benedikt Colen, Rivka Kotrotsou, Aikaterini Lamontagne, Pamela Marcus, Daniel Milchenko, Mikhail Nazeri, Arash Weber, Marc-Andr Mahajan, Abhishek Baid, Ujjwal Gerstner, Elizabeth Kwon, Dongjin Acharya, Gagan Agarwal, Manu Alam, Mahbubul Albiol, Alberto Albiol, Antonio Albiol, Francisco J. Alex, Varghese Allinson, Nigel Amorim, Pedro H.A. Amrutkar, Abhijit Anand, Ganesh Andermatt, Simon Arbel, Tal Arbelaez, Pablo Avery, Aaron Azmat, Muneeza Pranjal, B. Bai, Wenjia Banerjee, Subhashis Barth, Bill Batchelder, Thomas Batmanghelich, Kayhan Battistella, Enzo Beers, Andrew Belyaev, Mikhail Bendszus, Martin Benson, Eze Bernal, Jose Bharath, Halandur Nagaraja Biros, George Bisdas, Sotirios Brown, James Cabezas, Mariano Cao, Shilei Cardoso, Jorge M. Carver, Eric N. Casamitjana, Adri Castillo, Laura Silvana Cat, Marcel Cattin, Philippe Cérigues, Albert Chagas, Vinicius S. Chandra, Siddhartha Chang, Yi-Ju Chang, Shiyu Chang, Ken Chazalon, Joseph Chen, Shengcong Chen, Wei Chen, Jefferson W. Chen, Zhaolin Cheng, Kun Choudhury, Ahana Roy Chylla, Roger Clrigues, Albert Colleman, Steven Colmeiro, Ramiro German Rodriguez Combalia, Marc Costa, Anthony Cui, Xiaomeng Dai, Zhenzhen Dai, Lutao Daza, Laura Alexandra Deutsch, Eric Ding, Changxing Dong, Chao Dong, Shidu Dudzik, Wojciech Eaton-Rosen, Zach Egan, Gary Escudero, Guilherme Estienne, Tho Everson, Richard Fabrizio, Jonathan Fan, Yong Fang, Longwei Feng, Xue Ferrante, Enzo Fidon, Lucas Fischer, Martin French, Andrew P. Fridman, Naomi Fu, Huan Fuentes, David Gao, Yaozong Gates, Evan Gering, David Gholami, Amir Gierke, Willi Glocker, Ben Gong, Mingming Gonzlez-Vill, Sandra Grosges, T. Guan, Yuanfang Guo, Sheng Gupta, Sudeep Han, Woo-Sup Han, Il Song Harmuth, Ko Center for Biomedical Image Computing and Analytics University of Pennsylvania PhiladelphiaPA United States Department of Radiology Perelman School of Medicine University of Pennsylvania PhiladelphiaPA United States Department of Pathology and Laboratory Medicine Perelman School of Medicine University of Pennsylvania PhiladelphiaPA United States Institute for Surgical Technology and Biomechanics University of Bern Bern Switzerland Center for MR-Research University Children's Hospital Zurich Zurich Switzerland Support Centre for Advanced Neuroimaging Inselspital Institute for Diagnostic and Interventional Neuroradiology Bern University Hospital Bern Switzerland University Hospital of Zurich Zurich Switzerland Center for Clinical Epidemiology and Biostatistics University of Pennsylvania Philadelphia United States Image-Based Biomedical Modeling Group Technical University of Munich Munich Germany Icahn School of Medicine Mount Sinai Health System New YorkNY United States Leidos Biomedical Research Inc. Frederick National Laboratory for Cancer Research FrederickMD21701 United States Cancer Imaging Program National Cancer Institute National Institutes of Health BethesdaMD20814 United States Department of Neurology University of Alabama at Birmingham BirminghamAL United States Department of Diagnostic Radiology University of Texas MD Anderson Cancer Center HoustonTX United States Department of Psychology Washington University St. LouisMO United States Neuroimaging Informatics and Analysis Center Washington University St. LouisMO United States Department of Radiology Washington University St. LouisMO United States Institute of Diagnostic and Interventional Radiology Pediatric Radiology and Neuroradiology University Medical Center Rostock Ernst-Heydemann-Str. 6 Rostock18057 Germany Tata Memorial Centre Homi Bhabha National Institute Mumbai India Shri Guru Gobind Singhji Institute of Engineering and Technology Nanded India NVIDIA Santa Clara

Gliomas are the most common primary brain malignancies, with different degrees of aggressiveness, variable prognosis and various heterogeneous histologic sub-regions, i.e., peritumoral edematous/invaded tissue, necrotic core, active and non-enhancing core. This intrinsic heterogeneity is also portrayed in their radio-phenotype, as their sub-regions are depicted by varying intensity profiles disseminated across multi-parametric magnetic resonance imaging (mpMRI) scans, reflecting varying biological properties. Their heterogeneous shape, extent, and location are some of the factors that make these tumors difficult to resect, and in some cases inoperable. The amount of resected tumor is a factor also considered in longitudinal scans, when evaluating the apparent tumor for potential diagnosis of progression. Furthermore, there is mounting evidence that accurate segmentation of the various tumor sub-regions can offer the basis for quantitative image analysis towards prediction of patient overall survival. This study assesses the state-of-the-art machine learning (ML) methods used for brain tumor image analysis in mpMRI scans, during the last seven instances of the International Brain Tumor Segmentation (BraTS) challenge, i.e., 2012-2018. Specifically, we focus on i) evaluating segmentations of the various glioma sub-regions in pre-operative mpMRI scans, ii) assessing potential tumor progression by virtue of longitudinal growth of tumor sub-regions, beyond use of the RECIST/RANO criteria, and iii) predicting the overall survival from pre-operative mpMRI scans of patients that underwent gross total resection. Finally, we investigate the challenge of identifying the best ML algorithms for each of these tasks, considering that apart from being diverse on each instance of the challenge, the multi-institutional mpMRI BraTS dataset has also been a continuously evolving/growing dataset. Copyright © 2018, The Authors. All rights reserved.

关键词： Tumors

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