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arXiv 2022年

作者： Maier-Hein, Lena Reinke, Annika Godau, Patrick Tizabi, Minu D. Buettner, Florian Christodoulou, Evangelia Glocker, Ben Isensee, Fabian Kleesiek, Jens Kozubek, Michal Reyes, Mauricio Riegler, Michael A. Wiesenfarth, Manuel Emre Kavur, A. Sudre, Carole H. Baumgartner, Michael Eisenmann, Matthias Heckmann-Nötzel, Doreen Rädsch, Tim Acion, Laura Antonelli, Michela Arbel, Tal Bakas, Spyridon Benis, Arriel Blaschko, Matthew B. Jorge Cardoso, M. Cheplygina, Veronika Cimini, Beth A. Collins, Gary S. Farahani, Keyvan Ferrer, Luciana Galdran, Adrian Ginneken, Bram Van Haase, Robert Hashimoto, Daniel A. Hoffman, Michael M. Huisman, Merel Jannin, Pierre Kahn, Charles E. Kainmueller, Dagmar Kainz, Bernhard Karargyris, Alexandros Karthikesalingam, Alan Kenngott, Hannes Kofler, Florian Kopp-Schneider, Annette Kreshuk, Anna Kurc, Tahsin Landman, Bennett A. Litjens, Geert Madani, Amin Maier-Hein, Klaus Martel, Anne L. Mattson, Peter Meijering, Erik Menze, Bjoern Moons, Karel G.M. Müller, Henning Nichyporuk, Brennan Nickel, Felix Petersen, Jens Rajpoot, Nasir Rieke, Nicola Saez-Rodriguez, Julio Sánchez, Clara I. Shetty, Shravya Smeden, Maarten Van Summers, Ronald M. Taha, Abdel A. Tiulpin, Aleksei Tsaftaris, Sotirios A. Calster, Ben Van Varoquaux, Gaël Jäger, Paul F. Heidelberg Division of Intelligent Medical Systems and HI Helmholtz Imaging Germany Faculty of Mathematics and Computer Science and Medical Faculty Heidelberg University Heidelberg Germany NCT Heidelberg a partnership between DKFZ University Medical Center Heidelberg Germany Faculty of Mathematics and Computer Science Heidelberg University Heidelberg Germany Heidelberg Division of Intelligent Medical Systems Germany partner site Frankfurt/Mainz a partnership between DKFZ and UCT Frankfurt-Marburg Germany Heidelberg Goethe University Frankfurt Germany Department of Medicine Goethe University Frankfurt Germany Department of Informatics Frankfurt Cancer Insititute Germany Department of Computing Imperial College London London United Kingdom Heidelberg Division of Medical Image Computing and HI Applied Computer Vision Lab Germany Institute for AI in Medicine University Medicine Essen Essen Germany Centre for Biomedical Image Analysis Faculty of Informatics Masaryk University Brno Czech Republic ARTORG Center for Biomedical Engineering Research University of Bern Bern Switzerland Department of Radiation Oncology University Hospital Bern University of Bern Bern Switzerland Simula Metropolitan Center for Digital Engineering Oslo Norway UiT The Arctic University of Norway Romsø Norway Heidelberg Division of Biostatistics Germany Heidelberg Division of Intelligent Medical Systems Division of Medical Image Computing HI Applied Computer Vision Lab Germany MRC Unit for Lifelong Health and Ageing UCL Centre for Medical Image Computing Department of Computer Science University College London London United Kingdom School of Biomedical Engineering and Imaging Science King’s College London London United Kingdom Heidelberg Division of Medical Image Computing Germany Instituto de Cálculo CONICET – Universidad de Buenos Aires Buenos Aires Argentina Centre for Medical Image Computing University College London London United Kingdom McGill University Montréal

Increasing evidence shows that flaws in machine learning (ML) algorithm validation are an underestimated global problem. Particularly in automatic biomedical image analysis, chosen performance metrics often do not reflect the domain interest, thus failing to adequately measure scientific progress and hindering translation of ML techniques into practice. To overcome this, we created Metrics Reloaded, a comprehensive framework guiding researchers in the problem-aware selection of metrics. It was developed by a large international consortium in a multi-stage Delphi process and is based on the novel concept of a problem fingerprint – a structured representation of the given problem that captures all aspects that are relevant for metric selection, from the domain interest to the properties of the target structure(s), data set and algorithm output. Based on the problem fingerprint, users are guided through the process of choosing and applying appropriate validation metrics while being made aware of potential pitfalls. Metrics Reloaded targets image analysis problems that can be interpreted as a classification task at image, object or pixel level, namely image-level classification, object detection, semantic segmentation, and instance segmentation tasks. To improve the user experience, we implemented the framework in the Metrics Reloaded online tool. Following the convergence of ML methodology across application domains, Metrics Reloaded fosters the convergence of validation methodology. Its applicability is demonstrated for various biomedical use cases. © 2022, CC BY.

关键词： Semantic Segmentation

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A Scalable Deep Attention Mechanism of Instance Segmentation for the Investigation of Chromosome

引用

SLAS technology 2025年 33卷 100306页

作者： Neelam Umbreen Sara Ali Hasan Sajid Yasar Ayaz Shrooq Alsenan Yunyoung Nam So Yeon Kim Muhammad Baber Sial National University of Sciences and Technology (NUST) Islamabad Pakistan. Electronic address: neelamumbreen.phd@smme.edu.pk. National University of Sciences and Technology (NUST) Islamabad Pakistan Suzhou Industrial Park (SIP) Monash Research Institute of Science and Technology Monash University 8Q9C+R6W Suzhou Jiangsu China. School of Mechanical and Manufacturing Engineering (SMME) National University of Sciences and Technology (NUST) Islamabad NUST-COVENTRY Human-Robot Interaction (NC-HRI) Laboratory Pakistan Intelligent Field Robotics Laboratory (IFRL) National Center for Artificial Intelligence (NCAI) National University of Sciences and Technology (NUST) Islamabad Pakistan. Electronic address: sarababer@smme.nust.edu.pk. National University of Sciences and Technology (NUST) Islamabad Pakistan. Electronic address: hasan.sajid@smme.nust.edu.pk. Intelligent Field Robotics Laboratory (IFRL) National Center for Artificial Intelligence (NCAI) National University of Sciences and Technology (NUST) Islamabad Pakistan. Electronic address: yasar@smme.nust.edu.pk. Information Systems Department College of Computer and Information Sciences Princess Nourah bint Abdulrahman University P.O. Box 84428 Riyadh 11671 Saudi Arabia. Electronic address: shalsenan@pnu.edu.sa. Emotional and Intelligent Child Care Convergence Research Center Soonchunhyang University Asan 31538 Korea. Electronic address: ynam@sch.ac.kr. Department of Artificial Intelligence Department of Software and Computer Engineering Ajou University. Electronic address: jebi1771@ajou.ac.kr. School of Automation Science and Electrical Engineering Beihang University Beijing 100191 China. Electronic address: babersial@***.

Chromosome segmentation in metaphase images is a critical yet challenging task in cytogenetics and genomics due to the inherent complexity, variability in chromosome shapes, and the scarcity of high-quality annotated datasets. This study proposes a robust instance segmentation framework that integrates an automated annotation pipeline with an enhanced deep learning architecture to address these challenges. A novel dataset is introduced, comprising metaphase images and corresponding karyograms, annotated with precise instance segmentation information across 24 chromosome classes in COCO format. To overcome the labor-intensive manual annotation process, a feature-based image registration technique leveraging SIFT and homography is employed, enabling the accurate mapping of chromosomes from karyograms to metaphase images and significantly improving annotation quality and segmentation performance. The proposed framework includes a custom Mask R-CNN model enhanced with an Attention-based Feature Pyramid Network (AttFPN), spatial attention mechanisms, and a LastLevelMaxPool block for superior multi-scale feature extraction and focused attention on critical regions of the image. Experimental evaluations demonstrate the model's efficacy, achieving a mean average precision (mAP) of 0.579 at IoU = 0.50:0.95, surpassing the baseline Mask R-CNN and Mask R-CNN with AttFPN by 3.94% and 5.97% improvements in mAP and AP50, respectively. Notably, the proposed architecture excels in segmenting small and medium-sized chromosomes, addressing key limitations of existing methods. This research not only introduces a state-of-the-art segmentation framework but also provides a benchmark dataset, setting a new standard for chromosome instance segmentation in biomedical imaging. The integration of automated dataset creation with advanced model design offers a scalable and transferable solution, paving the way for tackling similar challenges in other domains of biomedical and cytogenetic imagi

关键词： Chromosome segmentation Instance segmentation, cytogenetics Mask R-CNN attention mechanism biomedical imaging multi-scale feature fusion

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Adaptive leader-follower formation control and obstacle avoidance via deep reinforcement learning

arXiv

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arXiv 2019年

作者： Zhou, Yanlin Lu, Fan Pu, George Ma, Xiyao Sun, Runhan Chen, Hsi-Yuan Li, Xiaolin Wu, Dapeng National Science Foundation Center for Big Learning Large-scale Intelligent Systems Laboratory Department of Electrical and Computer Engineering University of Florida GainesvilleFL United States Department of Mechanical and Aerospace Engineering University of Florida GainesvilleFL United States Amazon Robotics North Reading AI Institute Tongdun Technology

We propose a deep reinforcement learning (DRL) methodology for the tracking, obstacle avoidance, and formation control of nonholonomic robots. By separating vision-based control into a perception module and a controller module, we can train a DRL agent without sophisticated physics or 3D modeling. In addition, the modular framework averts daunting retrains of an image-to-action end-to-end neural network, and provides flexibility in transferring the controller to different robots. First, we train a convolutional neural network (CNN) to accurately localize in an indoor setting with dynamic foreground/background. Then, we design a new DRL algorithm named Momentum Policy Gradient (MPG) for continuous control tasks and prove its convergence. We also show that MPG is robust at tracking varying leader movements and can naturally be extended to problems of formation control. Leveraging reward shaping, features such as collision and obstacle avoidance can be easily integrated into a DRL controller. Copyright © 2019, The Authors. All rights reserved.

关键词： Deep learning

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Cost Optimal Control of Microgrids Having Solar Power and Energy Storage

Cost Optimal Control of Microgrids Having Solar Power and En...

引用

2018 IEEE/PES Transmission and Distribution Conference and Exposition, T and D 2018

作者： Gupta, Nikhil Francis, Griffin Ospina, Juan Newaz, Alvi Collins, Emmanuel G. Faruque, Omar Meeker, Rick Harper, Mario United States Center for Intelligent Systems Control and Robotics FAMU-FSU COE United States Department of Electrical and Computer Engineering FAMU-FSU COE United States Center for Advanced Power Systems FSU United States NHU Energy Inc. TallahasseeFL United States Department of Scientific Computing FSU United States

ISBN: (纸本)9781538655832

Solar power availability is intermittent and must be accompanied by an energy storage system (ESS) so that the effect of variability can be minimized. Hence, a strategy is needed to find the optimum combination of grid power, solar power, and power from the ESS so that the total cost of energy can be minimized. A solution to this problem is proposed here as Advanced Optimal Resource Allocation (AORA). This control scheme uses the prediction of Photovoltaic (PV) power availability, the real-time price of energy, and the levelized cost of energy for both PV and ESS to optimally combine the dispatch of power sources. Simulation results are presented for a 24 h prediction window and compared with a baseline power usage scheme that is based on a fixed charging and discharging schedule for the ESS. The comparison shows that AORA results in a substantial cost savings over the baseline scheme. © 2018 IEEE.

关键词： Forecasting

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Common Limitations of Image Processing Metrics: A Picture Story

arXiv

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arXiv 2021年

作者： Reinke, Annika Tizabi, Minu D. Sudre, Carole H. Eisenmann, Matthias Rädsch, Tim Baumgartner, Michael Acion, Laura Antonelli, Michela Arbel, Tal Bakas, Spyridon Bankhead, Peter Benis, Arriel Blaschko, Matthew Buettner, Florian Cardoso, M. Jorge Chen, Jianxu Cheplygina, Veronika Christodoulou, Evangelia Cimini, Beth A. Collins, Gary S. Engelhardt, Sandy Farahani, Keyvan Ferrer, Luciana Galdran, Adrian van Ginneken, Bram Glocker, Ben Godau, Patrick Haase, Robert Hamprecht, Fred Hashimoto, Daniel A. Heckmann-Nötzel, Doreen Hirsch, Peter Hoffman, Michael M. Huisman, Merel Isensee, Fabian Jannin, Pierre Kahn, Charles E. Kainmueller, Dagmar Kainz, Bernhard Karargyris, Alexandros Karthikesalingam, Alan Kavur, A. Emre Kenngott, Hannes Kleesiek, Jens Kleppe, Andreas Koehler, Sven Kofler, Florian Kopp-Schneider, Annette Kooi, Thijs Kozubek, Michal Kreshuk, Anna Kurc, Tahsin Landman, Bennett A. Litjens, Geert Madani, Amin Maier-Hein, Klaus Martel, Anne L. Mattson, Peter Meijering, Erik Menze, Bjoern Moher, David Moons, Karel G.M. Müller, Henning Nichyporuk, Brennan Nickel, Felix Noyan, M. Alican Petersen, Jens Polat, Gorkem Rafelski, Susanne M. Rajpoot, Nasir Reyes, Mauricio Rieke, Nicola Riegler, Michael A. Rivaz, Hassan Saez-Rodriguez, Julio Sánchez, Clara I. Schroeter, Julien Saha, Anindo Selver, M. Alper Sharan, Lalith Shetty, Shravya Smeden, Maarten V.A.N. Stieltjes, Bram Summers, Ronald M. Taha, Abdel A. Tiulpin, Aleksei Tsaftaris, Sotirios A. Calster, Ben V.A.N. Varoquaux, Gaël Wiesenfarth, Manuel Yaniv, Ziv R. Jäger, Paul Maier-Hein, Lena Division of Intelligent Medical Systems and HI Helmholtz Imaging Heidelberg Germany Faculty of Mathematics and Computer Science Heidelberg University Heidelberg Germany Division of Intelligent Medical Systems Heidelberg Germany NCT Heidelberg DKFZ University Medical Center Heidelberg Germany MRC Unit for Lifelong Health and Ageing UCL Centre for Medical Image Computing Department of Computer Science University College London London United Kingdom School of Biomedical Engineering and Imaging Science King’s College London London United Kingdom Division of Medical Image Computing Heidelberg Germany Instituto de Cálculo CONICET – Universidad de Buenos Aires Buenos Aires Argentina Centre for Medical Image Computing University College London London United Kingdom McGill University Montréal Canada Division of Computational Pathology Dept of Pathology & Laboratory Medicine Indiana University School of Medicine IU Health Information and Translational Sciences Building Indianapolis United States University of Pennsylvania Richards Medical Research Laboratories FL7 PhiladelphiaPA United States Institute of Genetics and Cancer University of Edinburgh Edinburgh United Kingdom Department of Digital Medical Technologies Holon Institute of Technology Holon Israel European Federation for Medical Informatics Le Mont-sur-Lausanne Switzerland Center for Processing Speech and Images Department of Electrical Engineering KU Leuven Kasteelpark Arenberg 10 - box 2441 Leuven3001 Belgium Frankfurt/Mainz DKFZ UCT Frankfurt-Marburg Germany Heidelberg Germany Goethe University Frankfurt Department of Medicine Germany Goethe University Frankfurt Department of Informatics Germany Frankfurt Cancer Insititute Germany Leibniz-Institut für Analytische Wissenschaften – ISAS – e.V. Dortmund Germany Department of Computer Science IT University of Copenhagen Copenhagen Denmark Imaging Platform Broad Institute of MIT and Harvard CambridgeMA United States Centre for St

While the importance of automatic image analysis is continuously increasing, recent meta-research revealed major flaws with respect to algorithm validation. Performance metrics are particularly key for meaningful, objective, and transparent performance assessment and validation of the used automatic algorithms, but relatively little attention has been given to the practical pitfalls when using specific metrics for a given image analysis task. These are typically related to (1) the disregard of inherent metric properties, such as the behaviour in the presence of class imbalance or small target structures, (2) the disregard of inherent data set properties, such as the non-independence of the test cases, and (3) the disregard of the actual biomedical domain interest that the metrics should reflect. This living dynamically document has the purpose to illustrate important limitations of performance metrics commonly applied in the field of image analysis. In this context, it focuses on biomedical image analysis problems that can be phrased as image-level classification, semantic segmentation, instance segmentation, or object detection task. The current version is based on a Delphi process on metrics conducted by an international consortium of image analysis experts from more than 60 institutions worldwide. © 2021, CC BY.

关键词： Medical imaging

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Wearable Flexible Hybrid Electronics: Advanced Soft Materials, Sensor Integrations, and Applications of Wearable Flexible Hybrid Electronics in Healthcare, Energy, and Environment (Adv. Mater. 15/2020)

引用

Advanced Materials 2020年第15期32卷

作者： Hyo‐Ryoung Lim Hee Seok Kim Raza Qazi Young‐Tae Kwon Jae‐Woong Jeong Woon‐Hong Yeo George W. Woodruff School of Mechanical Engineering Institute for Electronics and Nanotechnology Georgia Institute of Technology Atlanta GA 30332 USA Department of Mechanical Engineering University of South Alabama Mobile AL 36608 USA Department of Electrical Computer & Energy Engineering University of Colorado Boulder Boulder CO 80309 USA School of Electrical Engineering Korea Advanced Institute of Science and Technology Daejeon 34141 South Korea George W. Woodruff School of Mechanical Engineering Wallace H. Coulter Department of Biomedical Engineering Institute for Electronics and Nanotechnology Parker H. Petit Institute for Bioengineering and Biosciences Center for Flexible and Wearable Electronics Advanced Research Neural Engineering Center Institute for Materials Institute for Robotics and Intelligent Machines Georgia Institute of Technology Atlanta GA 30332 USA

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Unsupervised learning in reservoir computing for EEG-based emotion recognition

arXiv

引用

arXiv 2018年

作者： Fourati, Rahma Ammar, Boudour Sanchez-Medina, Javier Alimi, Adel M. Research Groups in Intelligent Machines Department of Electrical and Computer Engineering National Engineering School of Sfax University of Sfax Sfax3038 Tunisia Innovation Center for the Information Society University of Las Palmas de Gran Canaria Las Palmas de Gran Canaria Spain

In real-world applications such as emotion recognition from recorded brain activity, data are captured from electrodes over time. These signals constitute a multidimensional time series. In this paper, Echo State Network (ESN), a recurrent neural network with a great success in time series prediction and classification, is optimized with different neural plasticity rules for classification of emotions based on electroencephalogram (EEG) time series. Actually, the neural plasticity rules are a kind of unsupervised learning adapted for the reservoir, i.e. the hidden layer of ESN. More specifically, an investigation of Oja's rule, BCM rule and gaussian intrinsic plasticity rule was carried out in the context of EEG-based emotion recognition. The study, also, includes a comparison of the offline and online training of the ESN. When testing on the well-known affective benchmark"DEAP dataset" which contains EEG signals from 32 subjects, we find that pretraining ESN with gaussian intrinsic plasticity enhanced the classification accuracy and outperformed the results achieved with an ESN pretrained with synaptic plasticity. Four classification problems were conducted in which the system complexity is increased and the discrimination is more challenging, i.e. inter-subject emotion discrimination. Our proposed method achieves higher performance over the state of the art methods. Copyright © 2018, The Authors. All rights reserved.

关键词： Electroencephalography

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Stretchable Hybrid Electronics: Soft Modular Electronic Blocks (SMEBs): A Strategy for Tailored Wearable Health-Monitoring Systems (Adv. Sci. 5/2019)

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Advanced Science 2019年第5期6卷 1970025-1970025页

作者： Jaeyoung Yoon Yunsik Joo Eunho Oh Byeongmoon Lee Daesik Kim Seunghwan Lee Taehoon Kim Junghwan Byun Yongtaek Hong Department of Electrical and Computer Engineering Inter University Semiconductor Research Center (ISRC) Seoul National University Seoul 08826 Republic of Korea Department of Mechanical and Aerospace Engineering Institute of Advanced Machines and Design (IAMD) Soft Robotics Research Center (SRRC) Seoul National University Seoul 08826 Republic of Korea

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Multi-path region-based convolutional neural network for accurate detection of unconstrained "hard faces"

arXiv

引用

arXiv 2017年

作者： Liu, Yuguang Levine, Martin D. Department of Electrical and Computer Engineering Center for Intelligent Machines McGill University MontrealQC Canada

Large-scale variations still pose a challenge in unconstrained face detection. To the best of our knowledge, no current face detection algorithm can detect a face as large as 800 × 800 pixels while simultaneously detecting another one as small as 8 × 8 pixels within a single image with equally high accuracy. We propose a two-stage cascaded face detection framework, Multi-Path Region-based Convolutional Neural Network (MP-RCNN), that seamlessly combines a deep neural network with a classic learning strategy, to tackle this challenge. The first stage is a Multi-Path Region Proposal Network (MP-RPN) that proposes faces at three different scales. It simultaneously utilizes three parallel outputs of the convolutional feature maps to predict multi-scale candidate face regions. The "atrous" convolution trick (convolution with up-sampled filters) and a newly proposed sampling layer for "hard" examples are embedded in MP-RPN to further boost its performance. The second stage is a Boosted Forests classifier, which utilizes deep facial features pooled from inside the candidate face regions as well as deep contextual features pooled from a larger region surrounding the candidate face regions. This step is included to further remove hard negative samples. Experiments show that this approach achieves state-of-the-art face detection performance on the WIDER FACE dataset "hard" partition, outperforming the former best result by 9.6% for the Average Precision. Copyright © 2017, The Authors. All rights reserved.

关键词： Deep neural networks

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Aerial navigation in obstructed environments with embedded nonlinear model predictive control

arXiv

引用

arXiv 2018年

作者： Small, Elias Sopasakis, Pantelis Fresk, Emil Patrinos, Panagiotis Nikolakopoulos, George University of Cyprus Department of Electrical and Computer Engineering KIOS Research Center for Intelligent Systems and Networks 1 Panepistimiou Avenue Aglantzia Nicosia2109 Cyprus Robotics Team at Luleå Technical University LuleåSE-97187 Sweden KU Leuven Kasteelpark Arenberg 10 Leuven3001 Belgium

We propose a methodology for autonomous aerial navigation and obstacle avoidance of micro aerial vehicles (MAVs) using non-linear model predictive control (NMPC) and we demonstrate its effectiveness with laboratory experiments. The proposed methodology can accommodate obstacles of arbitrary, potentially non-convex, geometry. The NMPC problem is solved using PANOC: a fast numerical optimization method which is completely matrix-free, is not sensitive to ill conditioning, involves only simple algebraic operations and is suitable for embedded NMPC. A C89 implementation of PANOC solves the NMPC problem at a rate of 20 Hz on board a lab-scale MAV. The MAV performs smooth maneuvers moving around an obstacle. For increased autonomy, we propose a simple method to compensate for the reduction of thrust over time, which comes from the depletion of the MAV’s battery, by estimating the thrust *** Codes 49M37, 34H05, 93B52 Copyright © 2018, The Authors. All rights reserved.

关键词： Micro air vehicle (MAV)

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