This unit describes how to use Foldalign and FoldalignM to make structural alignments of non-protein-coding-rna (ncrna). These tools can be used to find new ncrnas, to find the structure of novel ncrnas, and to improv...
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Background: A classical problem in metabolic design is to maximize the production of a desired compound in a given chemical reaction network by appropriately directing the mass flow through the network. Computationall...
A key application of early methods for computational rna folding was to aid interpretation of structure probing *** the years computational rna biology has developed in which improved energy models and the availabilit...
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A key application of early methods for computational rna folding was to aid interpretation of structure probing *** the years computational rna biology has developed in which improved energy models and the availability of multiple genomes have contributed substantially to the development of the *** methods that search for common rna structures in a set of co-regulated rnas have
The avalanche of next generation sequencing data has led to a rapid increase of annotated micrornas in the last few years. Many of them are specific to individual species or rather narrow clades. A closer inspection o...
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