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Generating 3D TOF-MRA volumes and segmentation labels using generative adversarial networks

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Medical Image Analysis 2022年 78卷 102396-102396页

作者： Subramaniam, Pooja Kossen, Tabea Ritter, Kerstin Hennemuth, Anja Hildebrand, Kristian Hilbert, Adam Sobesky, Jan Livne, Michelle Galinovic, Ivana Khalil, Ahmed A. Fiebach, Jochen B. Frey, Dietmar Madai, Vince I. CLAIM - Charité Lab for AI in Medicine Charité Universitätsmedizin Berlin Germany Department of Computer Engineering and Microelectronics Computer Vision & Remote Sensing Technical University Berlin Berlin Germany Berlin Germany Bernstein Center for Computational Neuroscience Berlin Germany Institute for Imaging Science and Computational Modelling in Cardiovascular Medicine Charité Universitätsmedizin Berlin Berlin Germany Fraunhofer MEVIS Max-von-Laue-Str. 2 Bremen Germany Department VI Computer Science and Media Beuth University of Applied Sciences Berlin Germany Johanna-Etienne-Hospital Neuss Germany Centre for Stroke Research Berlin Charité Universitätsmedizin Berlin Berlin Germany Department of Neurology Max Planck Institute for Human Cognitive and Brain Sciences Leipzig Germany Mind Brain Body Institute Berlin School of Mind and Brain Humboldt University Berlin Berlin Germany Berlin Institute of Health Berlin Germany School of Computing and Digital Technology Faculty of Computing Engineering and the Built Environment Birmingham City University Birmingham United Kingdom QUEST-Center for Transforming Biomedical Research Berlin Institute of Health Charité Universitätsmedizin Berlin Charitéplatz 1 Berlin10117 Germany

Deep learning requires large labeled datasets that are difficult to gather in medical imaging due to data privacy issues and time-consuming manual labeling. Generative Adversarial Networks (GANs) can alleviate these challenges enabling synthesis of shareable data. While 2D GANs have been used to generate 2D images with their corresponding labels, they cannot capture the volumetric information of 3D medical imaging. 3D GANs are more suitable for this and have been used to generate 3D volumes but not their corresponding labels. One reason might be that synthesizing 3D volumes is challenging owing to computational limitations. In this work, we present 3D GANs for the generation of 3D medical image volumes with corresponding labels applying mixed precision to alleviate computational constraints. We generated 3D Time-of-Flight Magnetic Resonance Angiography (TOF-MRA) patches with their corresponding brain blood vessel segmentation labels. We used four variants of 3D Wasserstein GAN (WGAN) with: 1) gradient penalty (GP), 2) GP with spectral normalization (SN), 3) SN with mixed precision (SN-MP), and 4) SN-MP with double filters per layer (c-SN-MP). The generated patches were quantitatively evaluated using the Fréchet Inception Distance (FID) and Precision and Recall of Distributions (PRD). Further, 3D U-Nets were trained with patch-label pairs from different WGAN models and their performance was compared to the performance of a benchmark U-Net trained on real data. The segmentation performance of all U-Net models was assessed using Dice Similarity Coefficient (DSC) and balanced Average Hausdorff Distance (bAVD) for a) all vessels, and b) intracranial vessels only. Our results show that patches generated with WGAN models using mixed precision (SN-MP and c-SN-MP) yielded the lowest FID scores and the best PRD curves. Among the 3D U-Nets trained with synthetic patch-label pairs, c-SN-MP pairs achieved the highest DSC (0.841) and lowest bAVD (0.508) compared to the benchmark

关键词： Generative adversarial networks

Automated Controller Placement for Software-Defined Networks to Resist DDoS Attacks

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computers, Materials & Continua 2021年第9期68卷 3147-3165页

作者： Muhammad Reazul Haque Saw Chin Tan Zulfadzli Yusoff Kashif Nisar Lee Ching Kwang Rizaludin Kaspin Bhawani Shankar Chowdhry Rajkumar Buyya Satya Prasad Majumder Manoj Gupta Shuaib Memon Faculty of Computing&Informatics Multimedia UniversityPersiaran MultimediaCyberjaya63100SelangorMalaysia Faculty of Engineering Multimedia UniversityPersiaran MultimediaCyberjaya63100SelangorMalaysia Faculty of Computing and Informatics University Malaysia SabahJalan UMSKota Kinabalu Sabah88400Malaysia Telekom Malaysia Research&Development TM Innovation CentreCyberjaya63000SelangorMalaysia National Center of Robotics and Automation Mehran University of Engineering&TechnologyJamshoroPakistan Department of Computer Science and Engineering Hanyang UniversitySeoul04763South Korea School of Electrical and Electronic Engineering Nanyang Technological University639798Singapore Cloud Computing and Distributed Systems Laboratory The University of MelbourneMelbourneVIC 3053Australia Department of Electrical and Electronic Engineering Bangladesh University of Engineering and Technology(BUET)Dhaka1205Bangladesh Department of Electronics and Communication Engineering JECRC UniversityVidhaniJaipur303905India Auckland Institute of Studies Mt AlbertAucklandNew Zealand

In software-defined networks(SDNs),controller placement is a critical factor in the design and planning for the future Internet of Things(IoT),telecommunication,and satellite communication *** research has concentrated largely on factors such as reliability,latency,controller capacity,propagation delay,and energy ***,SDNs are vulnerable to distributed denial of service(DDoS)attacks that interfere with legitimate use of the *** ever-increasing frequency of DDoS attacks has made it necessary to consider them in network design,especially in critical applications such as military,health care,and financial services networks requiring high *** propose a mathematical model for planning the deployment of SDN smart backup controllers(SBCs)to preserve service in the presence of DDoS *** a number of input parameters,our model has two distinct ***,it determines the optimal number of primary controllers to place at specific locations or nodes under normal operating ***,it recommends an optimal number of smart backup controllers for use with different levels of DDoS *** goal of the model is to improve resistance to DDoS attacks while optimizing the overall cost based on the *** simulated results demonstrate that the model is useful in planning for SDN reliability in the presence of DDoS attacks while managing the overall cost.

关键词： SDN automated controller placement SBC ILP DDoS attack

Global and Local Mamba Network for Multi-Modality Medical Image Super-Resolution

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arXiv 2025年

作者： Ji, Zexin Zou, Beiji Kui, Xiaoyan Thureau, Sbastien Ruan, Su School of Computer Science and Engineering Central South University Changsha410083 China Hunan Engineering Research Center of Machine Vision and Intelligent Medicine Central South University Changsha410083 China University of Rouen-Normandy LITIS QuantIF UR 4108 RouenF-76000 France Department of Nuclear Medicine Henri Becquerel Cancer Center Rouen France

Convolutional neural networks and Transformer have made significant progresses in multi-modality medical image super-resolution. However, these methods either have a fixed receptive field for local learning or significant computational burdens for global learning, limiting the super-resolution performance. To solve this problem, State Space Models, notably Mamba, is introduced to efficiently model long-range dependencies in images with linear computational complexity. Relying on the Mamba and the fact that low-resolution images rely on global information to compensate for missing details, while high-resolution reference images need to provide more local details for accurate super-resolution, we propose a global and local Mamba network (GLMamba) for multi-modality medical image super-resolution. To be specific, our GLMamba is a two-branch network equipped with a global Mamba branch and a local Mamba branch. The global Mamba branch captures long-range relationships in low-resolution inputs, and the local Mamba branch focuses more on short-range details in high-resolution reference images. We also use the deform block to adaptively extract features of both branches to enhance the representation ability. A modulator is designed to further enhance deformable features in both global and local Mamba blocks. To fully integrate the reference image for low-resolution image super-resolution, we further develop a multi-modality feature fusion block to adaptively fuse features by considering similarities, differences, and complementary aspects between modalities. In addition, a contrastive edge loss (CELoss) is developed for sufficient enhancement of edge textures and contrast in medical images. Quantitative and qualitative experimental results show that our GLMamba achieves superior super-resolution performance on BraTS2021and IXI datasets. We also validate the effectiveness of our approach on the downstream tumor segmentation task. Copyright © 2025, The Authors. All rights res

关键词： Image coding

Why is the Winner the Best?

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Why is the Winner the Best?

Conference on computer vision and Pattern Recognition (CVPR)

作者： M. Eisenmann A. Reinke V. Weru M. D. Tizabi F. Isensee T. J. Adler S. Ali V. Andrearczyk M. Aubreville U. Baid S. Bakas N. Balu S. Bano J. Bernal S. Bodenstedt A. Casella V. Cheplygina M. Daum M. De Bruijne A. Depeursinge R. Dorent J. Egger D. G. Ellis S. Engelhardt M. Ganz N. Ghatwary G. Girard P. Godau A. Gupta L. Hansen K. Harada M. Heinrich N. Heller A. Hering A. Huaulmé P. Jannin A. E. Kavur O. Kodym M. Kozubek J. Li H. Li J. Ma C. Martín-Isla B. Menze A. Noble V. Oreiller N. Padoy S. Pati K. Payette T. Rädsch J. Rafael-Patiño V. Singh Bawa S. Speidel C. H. Sudre K. Van Wijnen M. Wagner D. Wei A. Yamlahi M. H. Yap C. Yuan M. Zenk A. Zia D. Zimmerer D. Aydogan B. Bhattarai L. Bloch R. Brüngel J. Cho C. Choi Q. Dou I. Ezhov C. M. Friedrich C. Fuller R. R. Gaire A. Galdran Á. García Faura M. Grammatikopoulou S. Hong M. Jahanifar I. Jang A. Kadkhodamohammadi I. Kang F. Kofler S. Kondo H. Kuijf M. Li M. Luu T. Martinčič P. Morais M. A. Naser B. Oliveira D. Owen S. Pang J. Park S. Park S. Płotka E. Puybareau N. Rajpoot K. Ryu N. Saeed A. Shephard P. Shi D. Štepec R. Subedi G. Tochon H. R. Torres H. Urien J. L. Vilaça K. A. Wahid H. Wang J. Wang L. Wang X. Wang B. Wiestler M. Wodzinski F. Xia J. Xie Z. Xiong S. Yang Y. Yang Z. Zhao K. Maier-Hein P. F. Jäger A. Kopp-Schneider L. Maier-Hein Division of Intelligent Medical Systems German Cancer Research Center (DKFZ) Heidelberg Germany Helmholtz Imaging German Cancer Research Center (DKFZ) Heidelberg Germany Faculty of Mathematics and Computer Science Heidelberg University Heidelberg Germany Division of Biostatistics German Cancer Research Center (DKFZ) Heidelberg Germany Division of Medical Image Computing German Cancer Research Center (DKFZ) Heidelberg Germany Faculty of Engineering and Physical Sciences School of Computing University of Leeds Leeds UK Institute of Informatics School of Management HES-SO Valais-Wallis University of Applied Sciences and Arts Western Switzerland Sierre Switzerland Department of Nuclear Medicine and Molecular Imaging Lausanne University Hospital Lausanne Switzerland Technische Hochschule Ingolstadt Ingolstadt Germany Center for Artificial Intelligence and Data Science for Integrated Diagnostics (AI2D) and Center for Biomedical Image Computing and Analytics (CBICA) University of Pennsylvania Philadelphia PA USA Department of Pathology and Laboratory Medicine Perelman School of Medicine University of Pennsylvania Philadelphia PA USA Department of Radiology Perelman School of Medicine University of Pennsylvania Philadelphia PA USA Department of Radiology University of Washington Seattle WA USA Department of Computer Science Wellcome/EPSRC Centre for Interventional and Surgical Sciences (WEISS) University College London London UK Universitat Autònoma de Barcelona & Computer Vision Center Barcelona Spain Division of Translational Surgical Oncology National Center for Tumor Diseases (NCT/UCC) Dresden Dresden Germany Department of Advanced Robotics Istituto Italiano di Tecnologia Italy Department of Electronics Information and Bioengineering Politecnico di Milano Milan Italy IT University of Copenhagen Copenhagen Denmark Department of General Visceral and Transplantation Surgery Heidelberg University Hospital Heidelberg Germany Department of Radiology and Nuc

International benchmarking competitions have become fundamental for the comparative performance assessment of image analysis methods. However, little attention has been given to investigating what can be learnt from these competitions. Do they really generate scientific progress? What are common and successful participation strategies? What makes a solution superior to a competing method? To address this gap in the literature, we performed a multicenter study with all 80 competitions that were conducted in the scope of IEEE ISBI 2021 and MICCAI 2021. Statistical analyses performed based on comprehensive descriptions of the submitted algorithms linked to their rank as well as the underlying participation strategies revealed common characteristics of winning solutions. These typically include the use of multi-task learning (63%) and/or multi-stage pipelines (61%), and a focus on augmentation (100%), image preprocessing (97%), data curation (79%), and post-processing (66%). The “typical” lead of a winning team is a computer scientist with a doctoral degree, five years of experience in biomedical image analysis, and four years of experience in deep learning. Two core general development strategies stood out for highly-ranked teams: the reflection of the metrics in the method design and the focus on analyzing and handling failure cases. According to the organizers, 43% of the winning algorithms exceeded the state of the art but only 11% completely solved the respective domain problem. The insights of our study could help researchers (1) improve algorithm development strategies when approaching new problems, and (2) focus on open research questions revealed by this work.

关键词：

BrainIB: Interpretable Brain Network-based Psychiatric Diagnosis with Graph Information Bottleneck

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arXiv 2022年

作者： Zheng, Kaizhong Yu, Shujian Li, Baojuan Jenssen, Robert Chen, Badong National Key Laboratory of Human-Machine Hybrid Augmented Intelligence National Engineering Research Center for Visual Information and Applications Institute of Artificial Intelligence and Robotics Xi’an Jiaotong University Xi’an China The Department of Computer Science Vrije Universiteit Amsterdam Amsterdam and the Machine Learning Group UiT - Arctic University of Norway Tromsø Norway The Machine Learning Group UiT - Arctic University of Norway Tromsø Norway The School of Biomedical Engineering Fourth Military Medical University Xi’an China

Developing a new diagnostic models based on the underlying biological mechanisms rather than subjective symptoms for psychiatric disorders is an emerging consensus. Recently, machine learning-based classifiers using functional connectivity (FC) for psychiatric disorders and healthy controls are developed to identify brain markers. However, existing machine learning-based diagnostic models are prone to over-fitting (due to insufficient training samples) and perform poorly in new test environment. Furthermore, it is difficult to obtain explainable and reliable brain biomarkers elucidating the underlying diagnostic decisions. These issues hinder their possible clinical applications. In this work, we propose BrainIB, a new graph neural network (GNN) framework to analyze functional magnetic resonance images (fMRI), by leveraging the famed Information Bottleneck (IB) principle. BrainIB is able to identify the most informative edges in the brain (i.e., subgraph) and generalizes well to unseen data. We evaluate the performance of BrainIB against 3 baselines and 7 state-of-the-art brain network classification methods on three psychiatric datasets and observe that our BrainIB always achieves the highest diagnosis accuracy. It also discovers the subgraph biomarkers which are consistent to clinical and neuroimaging findings. The source code and implementation details of BrainIB are freely available at GitHub repository (https://***/SJYuCNEL/brain-and-Information-Bottleneck/). Copyright © 2022, The Authors. All rights reserved.

关键词： Graph neural networks

BasisConv: A method for compressed representation and learning in CNNs

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arXiv 2019年

作者： Tayyab, Muhammad Mahalanobis, Abhijit Center for Research in Computer Vision Department of Computer Science University of Central Florida United States

It is well known that Convolutional Neural Networks (CNNs) have significant redundancy in their filter weights. Various methods have been proposed in the literature to compress trained CNNs. These include techniques like pruning weights, filter quantization and representing filters in terms of a basis functions. Our approach falls in this latter class of strategies, but is distinct in that that we show both compressed learning and representation can be achieved without significant modifications of popular CNN architectures. Specifically, any convolution layer of the CNN is easily replaced by two successive convolution layers: the first is a set of fixed filters (that represent the knowledge space of the entire layer and do not change), which is followed by a layer of one-dimensional filters (that represent the learned knowledge in this space). For the pre-trained networks, the fixed layer is just the truncated eigen-decompositions of the original filters. The 1D filters are initialized as the weights of linear combination, but are fine-tuned to recover any performance loss due to the truncation. For training networks from scratch, we use a set of random orthogonal fixed filters (that never change), and learn the 1D weight vector directly from the labeled data. Our method substantially reduces i) the number of learnable parameters during training, and ii) the number of multiplication operations and filter storage requirements during implementation. It does so without requiring any special operators in the convolution layer, and extends to all known popular CNN architectures. We demonstrate the generality of the proposed approach by applying it to four well known network architectures with three different data sets. The results show a consistent reduction in i) the number of operations by up to a factor of 5, and ii) number of learnable parameters by up to a factor of 18, with less than 3% drop in performance on the CIFAR100 dataset. Copyright © 2019, The Authors. All

关键词： Convolution

Ovarian Cysts Classification Using Novel Deep Q-Learning With Harris Hawks Optimization Method

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Research Square

research Square 2021年

作者： Narmatha, C. Manimegalai, P. Krishnadass, J. Valsalan, Prajoona Manimurugan, S. Karunya Institute of Technology and Sciences India Department of Computer Science Faculty of Computers and Information Technology University of Tabuk Tabuk Saudi Arabia Department of Biomedical Engineering Karunya Deemed University Tamil Nadu Coimbatore India Sahrdaya College of Engineering and Technology Kodakara India Department of Electrical and Computer Engineering Dhofar University Salalah Oman Scientific Research and Consultant Unit Industrial Innovation & Robotics Center Department of Information Technology Faculty of Computers and Information Technology University of Tabuk Tabuk Saudi Arabia

This research presents an essential solution for classifying ultrasound diagnostic images describing seven types of ovarian cysts: Follicular cyst, Hemorrhagic cyst, Corpus luteum cyst, Polycystic-appearing ovary, endometriosis cysts, Dermoid cyst, and Teratoma. This work proposed a novel technique using images of ovarian ultrasound cysts from an ongoing database with this motivation. Initially, the work is followed by removing noise in preprocessing, feature extraction, and finally classifying using new Deep Q-Network with Harris Hawks Optimization (HHO) classifier. Automatic feature extraction is implemented using the recent popular convolutional neural network (CNN) technique that extracts image features as conditions in the reinforcement learning algorithm. With this, through the procedure of a new deep Q-learning algorithm, Deep Q-Network (DQN) is generated to train a Q-network. The swarm-based method of HHO utilized the optimization method to produce optimal hyperparameters in the DQN model known as HHO-DQN, a novel technique for classifying ovarian cysts. Extensive experimental evaluations on datasets show that the proposed HHO- DQN approach outperforms existing active learning approaches for ovarian cyst classification. Compared with the ANN, CNN, and AlexNet models, the performance of the proposed model is better in terms of precision, f-measure, recall, accuracy, and IoU. The proposed model has achieved 96% precision, 96.5% f-measure, 96% recall, 97% accuracy, and 0.65 IoU. © 2021, CC BY.

关键词： Image classification

Dynamics and aerial attitude control for rapid emergency deployment of the agile ground robot AGRO

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arXiv 2020年

作者： Gonzalez, Daniel J. Lesak, Mark C. Rodriguez, Andres H. Cymerman, Joseph A. Korpela, Christopher M. Robotics Research Center Department of Electrical Engineering and Computer Science Army Cyber Institute Department of Civil and Mechanical Engineering United States Military Academy West PointNY10996 United States

In this work we present a Four-Wheeled Independent Drive and Steering (4WIDS) robot named AGRO and a method of controlling its orientation while airborne using wheel reaction torques. This is the first documented use of independently steerable wheels to both drive on the ground and achieve aerial attitude control when thrown. Inspired by a cat’s self-righting reflex, this capability was developed to allow emergency response personnel to rapidly deploy AGRO by throwing it over walls and fences or through windows without the risk of it landing upside down. It also allows AGRO to drive off of ledges and ensure it lands on all four wheels. We have demonstrated a successful thrown deployment of AGRO. A novel parametrization and singularity analysis of 4WIDS kinematics reveals independent yaw authority with simultaneous adjustment of the ratio between roll and pitch authority. Simple PD controllers allow for stabilization of roll, pitch, and yaw. These controllers were tested in a simulation using derived dynamic equations of motion, then implemented on the AGRO prototype. An experiment comparing a controlled and non-controlled fall was conducted in which AGRO was dropped from a height of 0.85 m with an initial roll and pitch angle of 16 degrees and -23 degrees respectively. With the controller enabled, AGRO can use the reaction torque from its wheels to stabilize its orientation within 402 milliseconds. Copyright © 2020, The Authors. All rights reserved.

关键词： Wheels

A Robust Ensemble Algorithm for Ischemic Stroke Lesion Segmentation: Generalizability and Clinical Utility Beyond the ISLES Challenge

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arXiv 2024年

作者： de la Rosa, Ezequiel Reyes, Mauricio Liew, Sook-Lei Hutton, Alexandre Wiest, Roland Kaesmacher, Johannes Hanning, Uta Hakim, Arsany Zubal, Richard Valenzuela, Waldo Robben, David Sima, Diana M. Anania, Vincenzo Brys, Arne Meakin, James A. Mickan, Anne Broocks, Gabriel Heitkamp, Christian Gao, Shengbo Liang, Kongming Zhang, Ziji Siddiquee, Md Mahfuzur Rahman Myronenko, Andriy Ashtari, Pooya Van Huffel, Sabine Jeong, Hyun-Su Yoon, Chi-Ho Kim, Chulhong Huo, Jiayu Ourselin, Sebastien Sparks, Rachel Clèrigues, Albert Oliver, Arnau Lladó, Xavier Chalcroft, Liam Pappas, Ioannis Bertels, Jeroen Heylen, Ewout Moreau, Juliette Hatami, Nima Frindel, Carole Qayyum, Abdul Mazher, Moona Puig, Domenec Lin, Shao-Chieh Juan, Chun-Jung Hu, Tianxi Boone, Lyndon Goubran, Maged Liu, Yi-Jui Wegener, Susanne Kofler, Florian Ezhov, Ivan Shit, Suprosanna Hernandez Petzsche, Moritz R. Menze, Bjoern Kirschke, Jan S. Wiestler, Benedikt Department of Quantitative Biomedicine University of Zurich Zurich Switzerland Department of Informatics Technical University Munich Germany Icometrix Leuven Belgium ARTORG Center for Biomedical Research University of Bern Bern Switzerland Department of Radiation Oncology University Hospital Bern University of Bern Switzerland University of Bern Bern Switzerland Chan Division of Occupational Science and Occupational Therapy University of Southern California Los AngelesCA United States Stevens Neuroimaging and Informatics Institute Department of Neurology Keck School of Medicine University of Southern California United States University Institute of Diagnostic and Interventional Neuroradiology Inselspital Bern Switzerland University Institute of Diagnostic and Interventional Neuroradiology University Hospital Bern Inselspital University of Bern Bern Switzerland Department of Diagnostic and Interventional neuroradiology University Medical Center Hamburg-Eppendorf Hamburg Germany Department of Medical Imaging Radboud University Medical Center Institute for Health Sciences Nijmegen Netherlands Deepwise AI Lab Beijing China Beijing University of Posts and Telecommunications Bejing China School of Computing and Augmented Intelligence Arizona State University TempeAZ United States NVIDIA Santa ClaraCA United States STADIUS Center for Dynamical Systems Signal Processing and Data Analytics KU Leuven Leuven Belgium Pohang Korea Republic of School of Biomedical Engineering & Imaging Sciences King’s College London United Kingdom Institute of Computer Vision and Robotics University of Girona Spain Wellcome Centre for Human Neuroimaging University College London London United Kingdom Laboratory of Neuro Imaging Stevens Institute for Neuroimaging and Informatics Keck School of Medicine University of Southern California Los Angeles United States KU Leuven Leuven Belgium CREATIS Université Lyon1 CNRS UMR5220 INSERM U1206 INSA-Lyon Villeurbanne696

Diffusion-weighted MRI (DWI) is essential for stroke diagnosis, treatment decisions, and prognosis. However, image and disease variability hinder the development of generalizable AI algorithms with clinical value. We address this gap by presenting a novel ensemble algorithm derived from the 2022 Ischemic Stroke Lesion Segmentation (ISLES) challenge. ISLES’22 provided 400 patient scans with ischemic stroke from various medical centers, facilitating the development of a wide range of cutting-edge segmentation algorithms by the research community. By assessing them against a hidden test set, we identified strengths, weaknesses, and potential biases. Through collaboration with leading teams, we combined top-performing algorithms into an ensemble model that overcomes the limitations of individual solutions. Our ensemble model combines the individual algorithms’ strengths and achieved superior ischemic lesion detection and segmentation accuracy (median Dice score: 0.82, median lesion-wise F1 score: 0.86) on our internal test set compared to individual algorithms. This accuracy generalized well across diverse image and disease variables. Furthermore, the model excelled in extracting clinical biomarkers like lesion types and affected vascular territories. Notably, in a Turing-like test, neuroradiologists consistently preferred the algorithm’s segmentations over manual expert efforts, highlighting increased comprehensiveness and precision. Validation using a real-world external dataset (N=1686) confirmed the model’s generalizability (median Dice score: 0.82, median lesion-wise F1 score: 0.86). The algorithm’s outputs also demonstrated strong correlations with clinical scores (admission NIHSS and 90-day mRS) on par with or exceeding expert-derived results, underlining its clinical relevance. This study offers two key findings. First, we present an ensemble algorithm that detects and segments ischemic stroke lesions on DWI across diverse scenarios on par with expert (neuro)rad

关键词： Diagnosis