DeePMD-kit is a powerful open-source software package that facilitates molecular dynamics simulations using machine learning potentials (MLP) known as Deep Potential (DP) models. This package, which was released in 20...
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In 2023, La Niña conditions that generally prevailed in the eastern Pacific Ocean from mid-2020 into early 2023 gave way to a strong El Niño by October. Atmospheric concentrations of Earth’s major greenhous...
In 2023, La Niña conditions that generally prevailed in the eastern Pacific Ocean from mid-2020 into early 2023 gave way to a strong El Niño by October. Atmospheric concentrations of Earth’s major greenhouse gases—carbon dioxide, methane, and nitrous oxide—all increased to record-high levels. The annual global average carbon dioxide concentration in the atmosphere rose to 419.3±0.1 ppm, which is 50% greater than the pre-industrial level. The growth from 2022 to 2023 was 2.8 ppm, the fourth highest in the record since the 1960s. The combined short-term effects of El Niño and the long-term effects of increasing levels of heat-trapping gases in the atmosphere contributed to new records for many essential climate variables reported here. The annual global temperature across land and oceans was the highest in records dating as far back as 1850, with the last seven months (June–December) having each been record warm. Over land, the globally averaged temperature was also record high. Dozens of countries reported record or near-record warmth for the year, including China and continental Europe as a whole (warmest on record), India and Russia (second warmest), and Canada (third warmest). Intense and widespread heatwaves were reported around the world. In Vietnam, an all-time national maximum temperature record of 44.2°C was observed at Tuong Duong on 7 May, surpassing the previous record of 43.4°C at Huong Khe on 20 April 2019. In Brazil, the air temperature reached 44.8°C in Araçuaí in Minas Gerais on 20 November, potentially a new national record and 12.8°C above normal. The effect of rising temperatures was apparent in the cryosphere, where snow cover extent by June 2023 was the smallest in the 56-year record for North America and seventh smallest for the Northern Hemisphere overall. Heatwaves contributed to the greatest average mass balance loss for Alpine glaciers around the world since the start of the record in 1970. Due to rapid volume loss beginning in 2021, St. A
Research software has become a central asset in academic research. It optimizes existing and enables new research methods, implements and embeds research knowledge, and constitutes an essential research product in its...
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Chronic care manages long-term, progressive conditions, while acute care addresses short-term conditions. Chronic conditions increasingly strain health systems, which are often unprepared for these demands. This study...
A1 Functional advantages of cell-type heterogeneity in neural circuits Tatyana O. Sharpee A2 Mesoscopic modeling of propagating waves in visual cortex Alain Destexhe A3 Dynamics and biomarkers of mental disorders Mits...
A1 Functional advantages of cell-type heterogeneity in neural circuits Tatyana O. Sharpee A2 Mesoscopic modeling of propagating waves in visual cortex Alain Destexhe A3 Dynamics and biomarkers of mental disorders Mitsuo Kawato F1 Precise recruitment of spiking output at theta frequencies requires dendritic h-channels in multi-compartment models of oriens-lacunosum/moleculare hippocampal interneurons Vladislav Sekulić, Frances K. Skinner F2 Kernel methods in reconstruction of current sources from extracellular potentials for single cells and the whole brains Daniel K. Wójcik, Chaitanya Chintaluri, Dorottya Cserpán, Zoltán Somogyvári F3 The synchronized periods depend on intracellular transcriptional repression mechanisms in circadian clocks. Jae Kyoung Kim, Zachary P. Kilpatrick, Matthew R. Bennett, Kresimir Josić O1 Assessing irregularity and coordination of spiking-bursting rhythms in central pattern generators Irene Elices, David Arroyo, Rafael Levi, Francisco B. Rodriguez, Pablo Varona O2 Regulation of top-down processing by cortically-projecting parvalbumin positive neurons in basal forebrain Eunjin Hwang, Bowon Kim, Hio-Been Han, Tae Kim, James T. McKenna, Ritchie E. Brown, Robert W. McCarley, Jee Hyun Choi O3 Modeling auditory stream segregation, build-up and bistability James Rankin, Pamela Osborn Popp, John Rinzel O4 Strong competition between tonotopic neural ensembles explains pitch-related dynamics of auditory cortex evoked fields Alejandro Tabas, André Rupp, Emili Balaguer-Ballester O5 A simple model of retinal response to multi-electrode stimulation Matias I. Maturana, David B. Grayden, Shaun L. Cloherty, Tatiana Kameneva, Michael R. Ibbotson, Hamish Meffin O6 Noise correlations in V4 area correlate with behavioral performance in visual discrimination task Veronika Koren, Timm Lochmann, Valentin Dragoi, Klaus Obermayer O7 Input-location dependent gain modulation in cerebellar nucleus neurons Maria Psarrou, Maria Schilstra, Neil Davey, Benjamin Torben-Ni
Can a PhD be of even greater benefit to a candidate than just the award of the PhD? This paper argues yes, A PhD is a process of learning by doing, during which the successful candidate discovers what being a research...
Can a PhD be of even greater benefit to a candidate than just the award of the PhD? This paper argues yes. A PhD is a process of learning by doing, during which the successful candidate discovers what being a research...
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ISBN:
(纸本)9781424413065
Can a PhD be of even greater benefit to a candidate than just the award of the PhD? This paper argues yes. A PhD is a process of learning by doing, during which the successful candidate discovers what being a researcher is all about, and how to write academically. The PhD dissertation is the artifact that demonstrates that the process has been undertaken successfully. It might appear that this is as much as you can expect from a PhD. Upon completion and successful defense, the intensity of focus and effort in the last stages often leaves the successful candidate almost bereft, so all consuming has this been. It would be asking too much perhaps to want more. This paper sets out to show that more should be required, not for the PhD itself, but to benefit the candidate even more. The question is how?
This article describes the results of one of the ten pilot programmes under the integrated manufacturing and service systems (IMSS) initiative pursued by the Agency for Science, Technology and Research (A* STAR) in Si...
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This article describes the results of one of the ten pilot programmes under the integrated manufacturing and service systems (IMSS) initiative pursued by the Agency for Science, Technology and Research (A* STAR) in Singapore. The objective of this particular programme is to investigate how design, analysis, enhancement and implementation of critical business processes in a manufacturing and service network can be realised using one single simulation/application framework. The overall architecture of the framework outlines how commercial simulation packages and Web-service based business process application components would have to be connected through a commercial application framework to achieve maximum leverage and re-usability of the applications involved. In the pilot phase of this programme, research issues were also addressed with regard to mechanisms for interoperation between commercial simulation packages, symbiotic interaction between simulation-based decision support components and physical systems, and simulation speed-up through multi-objective optimal computing budget allocation techniques on a grid infrastructure.
Summary form only given. Discussion from panellists representing different simulation schools of thought: software engineering, standardised simulation methodologies, simulation software vendors, traditional academic,...
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Summary form only given. Discussion from panellists representing different simulation schools of thought: software engineering, standardised simulation methodologies, simulation software vendors, traditional academic, and a typical simulation consumer/user.
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