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An algorithm for heterogeneous wireless network connections for user preferences and services

Scientific Reports 2025年第1期15卷 1-15页

作者： Krishnan, S. Dinesh Daniel, A. Ayyasamy, S. Balusamy, Balamurugan Selvarajan, Shitharth Al-Shehari, Taher Alsadhan, Nasser A. B V Raju Institute of Technology Telangana Narsapur India Amity University Madhya Pradesh Gwalior India Vellore Institute of Technology Vellore Campus Tamil Nadu Vellore India Associate Dean-Student Engagement Shiv Nadar University Gautam Buddha Nagar India Department of Computer Science Kebri Dehar University Kebri Dehar 250 Ethiopia Computer Skills Department of Self-Development Skill Common First Year Deanship King Saud University Riyadh 11362 Saudi Arabia Computer Science Department College of Computer and Information Sciences King Saud University Riyadh 12372 Saudi Arabia School of Built Environment Engineering and Computing Leeds Beckett University Leeds United Kingdom Department of Computer Science and Engineering Chennai Institute of Technology Chennai India Centre for Research Impact & Outcome Chitkara University Institute of Engineering and Technology Chitkara University Punjab Rajpura 140401 India

Heterogeneous wireless networks (HWNs) present a challenge in selecting the optimal network for user devices due to the overlapping availability of multiple networks. In order to help users choose the best HWN connection, this research is trying to build a decision-making framework that takes user preferences and network performance characteristics into account. Using a multi-attribute decision-making (MADM) method that incorporates fuzzy logic and the Fuzzy Analytic Hierarchy Process (FAHP), our goal is to improve the decision-making process for network selection. The suggested system takes into account a number of network metrics, including latency, jitter, bandwidth, and cost, and uses user preferences to determine the relative importance of each to guarantee a tailored and adaptable recommendation. Our results demonstrate that the algorithm greatly enhances the efficiency of network selection and the level of user happiness, with UMTS being the best option for conversational services, WiMAX being the best for streaming, and LTE being the best for interactive services. Through the incorporation of user-centric decision-making into the network selection process, this research enhances adaptive wireless communication systems, leading to better user experience and network efficiency. © The Author(s) 2025.

关键词： Fuzzy analysis hierarchy process Fuzzy logic Heterogeneous wireless networks Machine learning Multi-attribute decision-making approach

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The medical algorithmic audit (vol 4, pg e384, 2022)

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LANCET DIGITAL HEALTH 2022年第6期4卷 E405-E405页

作者： Liu, X. Glocker, B. McCradden, M. M. Ghassemi, M. Denniston, A. K. Oakden-Rayner, L. Academic Unit of Ophthalmology Institute of Inflammation and Ageing College of Medical and Dental Sciences University of Birmingham UK Department of Ophthalmology University Hospitals Birmingham NHS Foundation Trust Birmingham UK Moorfields Eye Hospital NHS Foundation Trust London UK Health Data Research UK London UK Birmingham Health Partners Centre for Regulatory Science and Innovation University of Birmingham Birmingham UK Biomedical Image Analysis Group Department of Computing Imperial College London London UK The Hospital for Sick Children Toronto ON Canada Dalla Lana School of Public Health Toronto ON Canada Institute for Medical Engineering and Science and Department of Electrical Engineering and Computer Science Massachusetts Institute of Technology Cambridge MA USA National Institute of Health Research Biomedical Research Centre for Ophthalmology Moorfields Hospital London NHS Foundation Trust London UK University College London Institute of Ophthalmology London UK Australian Institute for Machine Learning University of Adelaide Adelaide SA Australia. lauren.oakden-rayner@adelaide.edu.au

Artificial intelligence systems for health care, like any other medical device, have the potential to fail. However, specific qualities of artificial intelligence systems, such as the tendency to learn spurious correlates in training data, poor generalisability to new deployment settings, and a paucity of reliable explainability mechanisms, mean they can yield unpredictable errors that might be entirely missed without proactive investigation. We propose a medical algorithmic audit framework that guides the auditor through a process of considering potential algorithmic errors in the context of a clinical task, mapping the components that might contribute to the occurrence of errors, and anticipating their potential consequences. We suggest several approaches for testing algorithmic errors, including exploratory error analysis, subgroup testing, and adversarial testing, and provide examples from our own work and previous studies. The medical algorithmic audit is a tool that can be used to better understand the weaknesses of an artificial intelligence system and put in place mechanisms to mitigate their impact. We propose that safety monitoring and medical algorithmic auditing should be a joint responsibility between users and developers, and encourage the use of feedback mechanisms between these groups to promote learning and maintain safe deployment of artificial intelligence *** © 2022 The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY 4.0 license. Published by Elsevier Ltd.. All rights reserved.

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Assessing Trustworthy AI in Times of COVID-19: Deep Learning for Predicting a Multiregional Score Conveying the Degree of Lung Compromise in COVID-19 Patients

IEEE Transactions on Technology and Society

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IEEE Transactions on Technology and Society 2022年第4期3卷 272-289页

作者： Allahabadi, Himanshi Amann, Julia Balot, Isabelle Beretta, Andrea Binkley, Charles Bozenhard, Jonas Bruneault, Frederick Brusseau, James Candemir, Sema Cappellini, Luca Alessandro Chakraborty, Subrata Cherciu, Nicoleta Cociancig, Christina Coffee, Megan Ek, Irene Espinosa-Leal, Leonardo Farina, Davide Fieux-Castagnet, Genevieve Frauenfelder, Thomas Gallucci, Alessio Giuliani, Guya Golda, Adam Van Halem, Irmhild Hildt, Elisabeth Holm, Sune Kararigas, Georgios Krier, Sebastien A. Kuhne, Ulrich Lizzi, Francesca Madai, Vince I. Markus, Aniek F. Masis, Serg Mathez, Emilie Wiinblad Mureddu, Francesco Neri, Emanuele Osika, Walter Ozols, Matiss Panigutti, Cecilia Parent, Brendan Pratesi, Francesca Moreno-Sanchez, Pedro A. Sartor, Giovanni Savardi, Mattia Signoroni, Alberto Sormunen, Hanna-Maria Spezzatti, Andy Srivastava, Adarsh Stephansen, Annette F. Theng, Lau Bee Tithi, Jesmin Jahan Tuominen, Jarno Umbrello, Steven Vaccher, Filippo Vetter, Dennis Westerlund, Magnus Wurth, Renee Zicari, Roberto V. Ey Netherlands Enterprise Intelligence Department Amsterdam1083 HP Netherlands Eth Zurich Health Ethics and Policy Lab Department of Health Sciences and Technology Zürich8092 Switzerland Center for Diplomatic and Strategic Studies Postgraduate Studies in Diplomacy and International Relations Paris75015 France Pisa56124 Italy Hackensack Meridian Health Bioethics Center EdisonNJ08820 United States University of Oxford Faculty of Philosophy OxfordOX2 6GG United Kingdom Collège André- Laurendeau Philosophie Department MontrealQCH8N 2J4 Canada Université du Québec À Montréal École des Médias MontrealQCH2L 2C4 Canada Pace University Philosophy Department New YorkNY10038 United States The Ohio State University Wexner Medical Center Department of Radiology ColumbusOH43210 United States Humanitas Research Hospital Department of Radiology Milan20089 Italy Humanitas University Department of Biomedical Sciences Milan20089 Italy University of New England Faculty of Science Agriculture Business and Law ArmidaleNSW2351 Australia University of Technology Sydney Faculty of Engineering and Information Technology SydneyNSW2007 Australia Scuola Superiore Sant'Anna European Centre of Excellence on the Regulation of Robotics and Ai Pisa56127 Italy University of Bremen Group of Computer Architecture Bremen28359 Germany New York University Grossman School of Medicine Division of Infectious Diseases and Immunology Department of Medicine New YorkNY10016 United States Digital Institute Ai Research Section Stockholm16731 Sweden Arcada University of Applied Sciences Department of Business Management and Analytics Helsinki00550 Finland University of Brescia Radiological Sciences and Public Health Department of Medical and Surgical Specialties Brescia25121 Italy Sncf Reseau Sa Ethique Groupe La Plaine93418 France Institute of Diagnostic and Interventional Radiology University Hospital Zurich Zürich8091 Switzerland Eindhoven University of Tech

This article's main contributions are twofold: 1) to demonstrate how to apply the general European Union's High-Level Expert Group's (EU HLEG) guidelines for trustworthy AI in practice for the domain of healthcare and 2) to investigate the research question of what does 'trustworthy AI' mean at the time of the COVID-19 pandemic. To this end, we present the results of a post-hoc self-assessment to evaluate the trustworthiness of an AI system for predicting a multiregional score conveying the degree of lung compromise in COVID-19 patients, developed and verified by an interdisciplinary team with members from academia, public hospitals, and industry in time of pandemic. The AI system aims to help radiologists to estimate and communicate the severity of damage in a patient's lung from Chest X-rays. It has been experimentally deployed in the radiology department of the ASST Spedali Civili clinic in Brescia, Italy, since December 2020 during pandemic time. The methodology we have applied for our post-hoc assessment, called Z-Inspection®, uses sociotechnical scenarios to identify ethical, technical, and domain-specific issues in the use of the AI system in the context of the pandemic. © 2020 IEEE.

关键词： COVID-19

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Iterative pseudo-labeling based adaptive copy-paste supervision for semi-supervised tumor segmentation

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Knowledge-Based Systems 2025年 324卷

作者： Qiangguo Jin Hui Cui Junbo Wang Changming Sun Yimiao He Ping Xuan Linlin Wang Cong Cong Leyi Wei Ran Su School of Software Northwestern Polytechnical University Shaanxi China Yangtze River Delta Research Institute of Northwestern Polytechnical University Taicang China Department of Computer Science and Information Technology La Trobe University Melbourne Australia CSIRO Data61 Sydney Australia Department of Computer Science School of Engineering Shantou University Guangdong China Shandong Cancer Hospital and Institute Shandong First Medical University and Shandong Academy of Medical Sciences Shandong China Australian Institute of Health Innovation (AIHI) Macquarie University Australia School of Software Shandong University Shandong China Centre for Artificial Intelligence driven Drug Discovery Faculty of Applied Science Macao Polytechnic University Macao Special Administrative Region of China School of Computer Software College of Intelligence and Computing Tianjin University Tianjin China

Semi-supervised learning (SSL) has attracted considerable attention in medical image processing. The latest SSL methods use a combination of consistency regularization and pseudo-labeling to achieve remarkable success. However, most existing SSL studies focus on segmenting large organs, neglecting the challenging scenarios where there are numerous tumors or tumors of small volume. Furthermore, the extensive capabilities of data augmentation strategies, particularly in the context of both labeled and unlabeled data, have yet to be thoroughly investigated. To tackle these challenges, we introduce a straightforward yet effective approach, termed iterative pseudo-labeling based adaptive copy-paste supervision (IPA-CP), for tumor segmentation in CT scans. IPA-CP incorporates a two-way uncertainty based adaptive augmentation mechanism, aiming to inject tumor uncertainties present in the mean teacher architecture into adaptive augmentation. Additionally, IPA-CP employs an iterative pseudo-label transition strategy to generate more robust and informative pseudo labels for the unlabeled samples. Extensive experiments on both in-house and public datasets show that our framework outperforms state-of-the-art SSL methods in medical image segmentation. Ablation study results demonstrate the effectiveness of our technical contributions.

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Sparse code multiple access for 6G wireless communication networks: Recent advances and future directions

arXiv

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arXiv 2021年

作者： Yu, Lisu Liu, Zilong Wen, Miaowen Cai, Donghong Dang, Shuping Wang, Yuhao Xiao, Pei School of Information Engineering Nanchang University Nanchang330031 China State Key Laboratory of Computer Architecture Institute of Computing Technology Chinese Academy of Sciences Beijing100190 China School of Computer Science and Electronics Engineering University of Essex ColchesterCO4 3SQ United Kingdom School of Electronic and Information Engineering South China University of Technology Guangzhou510640 China College of Cyber Security Jinan University Guangzhou510632 China Thuwal23955-6900 Saudi Arabia Institute for Communication Systems 5G Innovation Centre University of Surrey GuildfordGU2 7XH United Kingdom

As 5G networks rolling out in many different countries nowadays, the time has come to investigate how to upgrade and expand them towards 6G, where the latter is expected to realize the interconnection of everything as well as the development of a ubiquitous intelligent mobile world for intelligent life. To enable this epic leap in communications, this article provides an overview and outlook on the application of sparse code multiple access (SCMA) for 6G wireless communication systems, which is an emerging disruptive non-orthogonal multiple access (NOMA) scheme for the enabling of massive connectivity. We propose to apply SCMA to a massively distributed access system (MDAS), whose architecture is based on fiber-based visible light communication (FVLC), ultra-dense network (UDN), and NOMA. Under this framework, we consider the interactions between optical front-hauls and wireless access links. In order to stimulate more upcoming research in this area, we outline a number of promising directions associated with SCMA for faster, more reliable, and more efficient multiple access in future 6G communication networks. © 2021, CC BY-NC-ND.

关键词： Visible light communication

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The computer Vision-based Tolerancing Callout Detection Model

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Procedia CIRP 2020年 92卷 134-139页

作者： Xin Deng Tukun Li Yuanping Xu Yanlong Cao Chao Kong Errui Zhang School of Software Engineering Chengdu University of Information Technology Chengdu China EPSRC Future Advanced Metrology Hub Centre for Precision Technologies School of Computing and Engineering University of Huddersfield Huddersfield HD1 3DH UK Shandong Industrial Technology Research Institute of Zhejiang University Shandong 277500 China College of Engineering and Computer Science Australia National University Canberra ACT 2600 Australia

Tolerancing symbols play an important role in mechanical product drawings, and they directly determine the functions, mating properties, interchangeability and working life of geometrical products. A symbolic tolerancing callout containing a set of symbols represents a set of pre-ordered operations with attributes. It includes an amount of knowledge from the drawing and standard documents, which is often reconstructed manually by engineers. Thus, at the same time, a symbolic tolerancing callout makes it difficult for the end-user to understand and interpret these callouts manually. To this end, this study puts forward a tolerancing callout detection model via the use of off-the-shelf costumer-grade cameras on current mobile devices for extracting and recognizing tolerancing callout blocks and symbols in them intelligently. This model has four core components: image preprocessing, callout location and extraction, symbol and character segmentation, and deep learning-based symbol recognition. The image preprocessing component is developed to remove the interferences on the target technical drawings through the corresponding morphological methods. This study proposes a novel solution on callout block locations and extractions in callout intensive scenarios since the callout locations and extractions can directly affect the accuracy of symbol and character recognitions. Then, Huff Transform and improved projection methods have been devised to symbol and character segmentations. Finally, this study constructed a convolutional neural network (CNN) to train a symbol recognition model. The experimental results show that the proposed model gains applicability on intelligent callout extractions and the corresponding symbol recognitions.

关键词： Tolerancing symbols Callout location extraction Symbol character segmentation CNN

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A secure medical image encryption technique based on DNA cryptography with elliptic curves

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Scientific reports 2025年第1期15卷 20003页

作者： V N Senthil Kumaran T Manikandan Rajesh Kumar Dhanaraj Taher Al-Shehari Nasser A Alsadhan Shitharth Selvarajan Department of Electronics and Communication Engineering SRM Institute of Science and Technology Tiruchirappalli Campus Tiruchirappalli India. Department of Computer Science and Business Systems Rajalakshmi Engineering College Thandalam India. Symbiosis Institute of Computer Studies and Research (SICSR) Symbiosis International (Deemed University) Pune India. Computer Skills Department of Self-Development Skill Common First Year Deanship King Saud University 11362 Riyadh Saudi Arabia. Computer Science Department College of Computer and Information Sciences King Saud University 12372 Riyadh Saudi Arabia. Department of Computer Science Kebri Dehar University 250 Kebri Dehar Ethiopia. ShitharthS@kdu.edu.et. Department of Computer Science and Engineering Chennai Institute of Technology Chennai India. ShitharthS@kdu.edu.et. Centre for Research Impact & Outcome Chitkara University Institute of Engineering and Technology Chitkara University Rajpura Punjab 140401 India. ShitharthS@kdu.edu.et. School of Built Environment Engineering and Computing Leeds Beckett University LS6 3HF Leeds UK. ShitharthS@kdu.edu.et.

Health services and telemedicine have proven to be an important area for information protection in research, especially with medical services and smart health care applications. In these systems, medical imaging protection are important not only for clinical diagnosis, but also to protect the very sensitive and confidential patient data. With progress in imaging technologies and biomedical processing algorithms, the amount of image data increases rapidly. However, securing this information while transferring through insecure channel is still a constant challenge. Existing encryption techniques often face limitations such as high computational complexity, insufficient security against advanced cryptographic attacks, poor reversal and pixel correlation. To overcome these challenges, the proposed approach provides an innovative hybrid encryption technique that integrates DNA cryptography with Elliptical Curve Cryptography (ECC). The DNA-based coding shows high randomness and equality while the ECC provides strong security and confidentiality. The DNA encoding and secure key generation are employed in the proposed technique to obtain the encrypted medical image. The combination of these techniques addresses the main boundaries of existing disadvantage by increasing both security and calculation efficiency, making it well suited for real time medical applications. The experimental analysis was carried out with various parameters like histogram analysis, correlation coefficient, Chi square, MSE, PSNR, entropy etc. The result analysis states that the proposed methodology outperforms the state-of-the-art existing methods with enhanced performance such as entropy of 7.9981, Correlation coefficient of 0.0019 and PSNR of 53.97. Also, the proposed methodology is tested for runtime analysis, memory analysis and security analysis.

关键词： Applied AI Biomedical image encryption DNA encoding Elliptic curve cryptography Secure key generation Security

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An Early Stage Researcher's Primer on Systems Medicine Terminology

Network and Systems Medicine

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Network and Systems Medicine 2021年第1期4卷 2-50页

作者： Zanin, Massimiliano Aitya, Nadim A.A. Basilio, José Baumbach, Jan Benis, Arriel Behera, Chandan K. Bucholc, Magda Castiglione, Filippo Chouvarda, Ioanna Comte, Blandine Dao, Tien-Tuan Ding, Xuemei Pujos-Guillot, Estelle Filipovic, Nenad Finn, David P. Glass, David H. Harel, Nissim Iesmantas, Tomas Ivanoska, Ilinka Joshi, Alok Boudjeltia, Karim Zouaoui Kaoui, Badr Kaur, Daman Maguire, Liam P. McClean, Paula L. McCombe, Niamh De Miranda, João Luís Moisescu, Mihnea Alexandru Pappalardo, Francesco Polster, Annikka Prasad, Girijesh Rozman, Damjana Sacala, Ioan Sanchez-Bornot, Jose M. Schmid, Johannes A. Sharp, Trevor Solé-Casals, Jordi Spiwok, Vojtěch Spyrou, George M. Stalidzans, Egils Stres, Blaa Sustersic, Tijana Symeonidis, Ioannis Tieri, Paolo Todd, Stephen Van Steen, Kristel Veneva, Milena Wang, Da-Hui Wang, Haiying Wang, Hui Watterson, Steven Wong-Lin, Kongfatt Yang, Su Zou, Xin Schmidt, Harald H.H.W. Centro de Tecnología Biomédica Universidad Politécnica de Madrid Madrid Spain Intelligent Systems Research Centre School of Computing Engineering and Intelligent Systems Ulster University Ulster United Kingdom Center for Physiology and Pharmacology Institute of Vascular Biology and Thrombosis Research Medical University of Vienna Vienna Austria TUM School of Life Sciences Weihenstephan Technical University of Munich Freising Germany Holon Israel CNR National Research Council IAC Institute for Applied Computing Rome Italy Lab of Computing Medical Informatics and Biomedical Imaging Technologies School of Medicine Aristotle University of Thessaloniki Thessaloniki Greece Université Clermont Auvergne INRAE UNH Plateforme d'Exploration du Métabolisme MetaboHUB Clermont Clermont-Ferrand France Université de Technologie de Compiègne Compiègne France Labex MS2T Control of Technological Systems-of-Systems CNRS and Université de Technologie de Compiègne Compiègne France Faculty of Engineering University of Kragujevac Kragujevac Serbia Kragujevac Serbia Steinbeis Advanced Risk Technologies Institute Doo Kragujevac Kragujevac Serbia Pharmacology and Therapeutics School of Medicine Galway Neuroscience Centre National University of Ireland Galway Ireland School of Computing Ulster University Ulster United Kingdom Holon Israel Department of Mathematics and Natural Sciences Kaunas University of Technology Kaunas Lithuania Faculty of Computer Science and Engineering Ss. Cyril and Methodius University Skopje Macedonia Medicine Faculty Université Libre de Bruxelles CHU de Charleroi Charleroi Belgium Northern Ireland Centre for Stratified Medicine Biomedical Sciences Research Institute Ulster University Ulster United Kingdom Escola Superior de Tecnologia e Gestão Instituto Politécnico de Portalegre Portalegre Portugal Instituto Superior Técnico Universidade de Lisboa Lisboa Portugal Faculty of Automatic Control and Computers University Politehnica of B

Background: Systems Medicine is a novel approach to medicine, that is, an interdisciplinary field that considers the human body as a system, composed of multiple parts and of complex relationships at multiple levels, and further integrated into an environment. Exploring Systems Medicine implies understanding and combining concepts coming from diametral different fields, including medicine, biology, statistics, modeling and simulation, and data science. Such heterogeneity leads to semantic issues, which may slow down implementation and fruitful interaction between these highly diverse fields. Methods: In this review, we collect and explain more than100 terms related to Systems Medicine. These include both modeling and data science terms and basic systems medicine terms, along with some synthetic definitions, examples of applications, and lists of relevant references. Results: This glossary aims at being a first aid kit for the Systems Medicine researcher facing an unfamiliar term, where he/she can get a first understanding of them, and, more importantly, examples and references for digging into the topic. © Massimiliano Zanin et al., 2021;Published by Mary Ann Liebert, Inc. 2021.

关键词： Semantics

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Quantifying dynamical coherence with coherence measures

arXiv

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arXiv 2021年

作者： Kim, Sunho Xiong, Chunhe Kumar, Asutosh Zhang, Guijun Wu, Junde School of Mathematical Sciences Harbin Engineering University Harbin150001 China School of Computer and Computing Science Zhejiang University City College Hangzhou310015 China P.G. Department of Physics Gaya College Magadh University Rampur Gaya823001 India Harish-Chandra Research Institute HBNI Chhatnag Road Jhunsi Allahabad211019 India Vaidic and Modern Physics Research Centre Bhagal Bhim Bhinmal Jalore343029 India School of Mathematical Sciences Zhejiang University Hangzhou310027 China

Quantum coherence, like entanglement, is a fundamental resource in quantum information. In recent years, remarkable progress has been made in formulating resource theory of coherence from a broader perspective. The notions of block-coherence and POVM-based coherence have been established. Certain challenges, however, remain to be addressed. It is difficult to define incoherent operations directly, without requiring incoherent states, which proves a major obstacle in establishing the resource theory of dynamical coherence. In this paper, we overcome this limitation by introducing an alternate definition of incoherent operations, induced via coherence measures, and quantify dynamical coherence based on this definition. Finally, we apply our proposed definition to quantify POVM-based dynamical coherence. © 2021, CC BY.

关键词： Quantum entanglement

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Unleashing the Strengths of Unlabeled Data in Pan-cancer Abdominal Organ Quantification: The FLARE22 Challenge

arXiv

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arXiv 2023年

作者： Ma, Jun Zhang, Yao Gu, Song Ge, Cheng Ma, Shihao Young, Adamo Zhu, Cheng Meng, Kangkang Yang, Xin Huang, Ziyan Zhang, Fan Liu, Wentao Pan, YuanKe Huang, Shoujin Wang, Jiacheng Sun, Mingze Xu, Weixin Jia, Dengqiang Choi, Jae Won Alves, Natália de Wilde, Bram Koehler, Gregor Wu, Yajun Wiesenfarth, Manuel Zhu, Qiongjie Dong, Guoqiang He, Jian Wang, Bo He, Junjun Yang, Hua Yang, Huihua Huang, Bingding Lyu, Mengye Ma, Yongkang Guo, Heng Zhang, Rongguo Maier-Hein, Klaus The Department of Laboratory Medicine and Pathobiology University of Toronto Peter Munk Cardiac Centre University Health Network Vector Institute Toronto Canada Shanghai AI Laboratory Shanghai200232 China The Department of Image Reconstruction Nanjing Anke Medical Technology Co. Ltd. Nanjing211113 China Ocean University of China Qingdao266100 China The Department of Computer Science University of Toronto Peter Munk Cardiac Centre University Health Network Vector Institute Toronto Canada Tinavi Medical Technologies Co. Ltd. Beijing100192 China University of Science and Technology Beijing Beijing100083 China The School of Biomedical Engineering Health Science Center Shenzhen University Shenzhen518055 China The Department of Radiological Algorithm Fosun Aitrox Information Technology Co. Ltd. Shanghai200033 China The School of Artificial Intelligence Beijing University of Posts and Telecommunications Beijing100876 China Shenzhen Technology University Shenzhen518000 China Xiamen University Xiamen361005 China Alibaba Beijing100084 China Infervision Medical Technology Co. Ltd. Beijing100025 China Hong Kong Centre for Cerebro-cardiovascular Health Engineering 000000 Hong Kong The Department of Radiology Armed Forces Yangju Hospital Yangju11429 Korea Republic of The Department of Radiology Radboudumc Nijmegen6525XZ Netherlands The Department of Medical Image Computing German Cancer Research Center Heidelberg69120 Germany ShenZhen Yorktal DMIT LLC Shenzhen518100 China Heidelberg69120 Germany The Department of Nuclear Medicine Nanjing Drum Tower Hospital Nanjing210008 China The College of Big Data and Internet Shenzhen Technology University Shenzhen518188 China The College of Health Science and Environmental Engineering Shenzhen Technology University Shenzhen China The Manteia Technologies Co. Ltd Xiamen China The Alibaba DAMO Academy Beijing China The Peter Munk Cardiac Centre University Health Network Department of Laboratory M

Quantitative organ assessment is an essential step in automated abdominal disease diagnosis and treatment planning. Artificial intelligence (AI) has shown great potential to automatize this process. However, most existing AI algorithms rely on many expert annotations and lack a comprehensive evaluation of accuracy and efficiency in real-world multinational settings. To overcome these limitations, we organized the FLARE 2022 Challenge, the largest abdominal organ analysis challenge to date, to benchmark fast, low-resource, accurate, annotation-efficient, and generalized AI algorithms. We constructed an intercontinental and multinational dataset from more than 50 medical groups, including Computed Tomography (CT) scans with different races, diseases, phases, and manufacturers. We independently validated that a set of AI algorithms achieved a median Dice Similarity Coefficient (DSC) of 90.0% by using 50 labeled scans and 2000 unlabeled scans, which can significantly reduce annotation requirements. The best-performing algorithms successfully generalized to holdout external validation sets, achieving a median DSC of 89.5%, 90.9%, and 88.3% on North American, European, and Asian cohorts, respectively. They also enabled automatic extraction of key organ biology features, which was labor-intensive with traditional manual measurements. This opens the potential to use unlabeled data to boost performance and alleviate annotation shortages for modern AI models. © 2023, CC BY-NC-ND.

关键词： Diseases

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