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IEEE Conference on Decision and control

作者： Gautam Kumar Vikram Aggarwal Nitish V. Thakor Marc H. Schieber Mayuresh V. Kothare Chemical Process Modeling and Control Center Department of Chemical Engineering Lehigh University Bethlehem PA USA Department of Biomedical Engineering Johns Hopkins University Baltimore MD USA Department of Neurobiology and Anatomy University of Rochester Medical Center Rochester NY USA

ISBN: (纸本)9781612848006;9781612848013

A control-theoretic study of complex systems such as closed-loop neural prostheses exhibits several challenges, from the design of an optimal feedback control problem to its solution. In this paper we study one such system, a closed-loop voluntary movement of a prosthetic finger using electrophysio-logical activities of a single cortical motor neuron. We develop an optimal feedback control problem in the nonlinear receding horizon based terminal set constraint framework. We analyze the feasibility and stability of the control problem. Further, we solve the control problem numerically by implementing a local optimum based nonconvex nonlinear programming algorithm. Finally, we study effects of visual and proprioceptive feedback pathways on the closed-loop system. Our results elucidate the importance of multiple feedback paths in designing a closed-loop neural prosthetic system.

关键词： Prosthetics Neurons Visualization Noise Optimization Torque Indexes

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Individual-based Modelling of Non-motile Bacterial Colony Formation In Structured Foods: A Comparative Study

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IFAC Proceedings Volumes 2010年第6期43卷 329-334页

作者： A.J. Verhulst A.M. Cappuyns E. Van Derlinden K. Bernaerts J.F.M. Van Impe CPMF - Flemish Cluster Predictive Microbiology in Foods www.cpmf2.be Chemical and Biochemical Process Technology and Control (BioTeC) Dept. of Chemical Engineering Katholieke Universiteit Leuven W. de Croylaan 46 3001 Heverlee Belgium

Microbial dynamics in structured food products differ from microbial dynamics in liquids. In structured products, microorganisms are immobilised and constrained to grow as colonies, as opposed to liquid, where bacteria grow planktonically, i.e., dispersed or free-living. Little information is available on the displacement mechanisms within colony formation of non-motile bacteria. Three displacement mechanisms can be found in literature, i.e., (i) a discrete cellular automaton (CA) mechanism, (ii) a moving boundary mechanism, and (iii) a shoving mechanism. All three mechanisms are implemented in an individual-based modelling (IbM) environment. Advantages and disadvantages of each approach with respect to the individualbased modelling approach are summarised. The discrete CA results in the least realistic colony formation, but has the advantage of great computational speed. Both the moving boundary and the shoving mechanism produce biologically realistic results, albeit at a different level of detail for the representation of the environment. Both are suitable for IbM implementation and the choice depends on the level of detail necessary to describe the microbial phenomena under study.

关键词： predictive microbiology cellular automaton individual-based modelling submerged colony dynamics bacterial movement

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Timed approximations of hybrid processes for controller verification

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IFAC Proceedings Volumes 1999年第2期32卷 4782-4787页

作者： Olaf Stursberg Sebastian Engell Stefan Kowalewski Process Control Laboratory Chemical Engineering Dept. University of Dortmund D-44221 Dortmund Phone: +49 (0)231 9700 351 Fax: +49 (0)231 7555129 (Germany)

The task of verifying the correct (with respect to a given specification) behaviour of discrete event controllers for continuous processes requires to combine model types of continuous and of discrete nature. In this contribution, the verification problem is treated by approximating the continuous dynamics using automata models, and by carrying out a reachability analysis in the discrete domain. The focus is on different methods to generate timed automata and hybrid automata from switched continuous systems. Furthermore, some model properties and their effects on the analysis results are discussed.

关键词： Automata Hybrid systems Discretization Model approximation Linear programming Reachability Verification

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PREDICTIVE ON-OFF COST MINIMIZING control OF A MUNICIPAL WASTE WATER TREATMENT PLANT

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IFAC Proceedings Volumes 2005年第1期38卷 43-48页

作者： U. Schmitz R. Haber F. Lang Dept. of Plant Design and Chemical Process Engineering Lab. of Process Control University of Applied Science Cologne D-50679 Köln Betzdorfer Str. 2 Germany fax: +49-221-8275-2201

With intermittently operated municipal waste water plants the aeration switching sequence should be optimized under the constraints that the solved nitrogen concentration in effluent has to be kept within its environmental limits. This is a highly nonlinear control problem because of the nonlinear biological process model ASM1 (Activated Sludge Model 1), the on-off state of the manipulated sequence and the concentration constraints. The constrained optimization was transformed to the unconstrained optimization of the predictive on-off control, as the violations of the constraints were converted to their economical costs. Furthermore, the cost of the aeration was considered in the cost function.

关键词： predictive control municipal waste water treatment nonlinear models

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control of a Heat-Integrated Complex Distillation Configuration

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IFAC Proceedings Volumes 1989年第8期22卷 69-76页

作者： S.S. Ding W.L. Luyben Eastman Kodak Company 2400 Mt. Read Boulevard Rochester New York 14652 USA Process Modeling and Control Center Department of Chemical Engineering Lehigh University 111 Research Drive Bethlehem PA 18015 USA

Several steadystate design studies of distillation systems that combine complex configurations (prefractionators and sidestream columns) and heat integration have appeared in the literature and have shown the potential for large reductions (50%) in energy consumption compared to conventional designs. However, the dynamics and control aspects of these highly interactive and multivariable systems have been virtually unexplored. This paper presents the results of computer simulation studies of the dynamic controllability of a complex heat-integrated distillation system for the ternary mixture of benzene, toluene and m-xylene. Both low and high-purity separations were explored. For the low-purity (95% product purities) separation, the complex heat-integrated system was found to be controllable and gave dynamic responses that were comparable to the simple conventional system. A diagonal multi-loop SISO controller structure was successful in controlling this 3x3 multivariable process. controlled variables were the three product purities. Manipulated variables were the flow rates of reflux, sidestream and reboiler steam. For the high-purity (99.9%) separation, the complex heat-integrated system was found to be controllable but could only handle small (<10%) feed composition disturbances and was dynamically worse than the conventional system. The control structure used in the low-purity separation did not work in the high-purity separation because of severe nonlinearity. To decrease the nonlinearity, a control structure was developed that maintained the two impurities in the toluene sidestream product instead of the toluene purity. The additional manipulated variable needed in this modified process (now a 4x4 multivariable process) was achieved by changing the sidestream drawoff-tray location.

关键词： Heat integration distillation control multivariable processes

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Neural network-based feedforward control of two-stage heat exchange process

Neural network-based feedforward control of two-stage heat e...

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IEEE International Conference on Systems, Man and Cybernetics

作者： A. Blazina N. Bolf Dept. of Meas. & Autom. Process Control Zagreb Univ. Croatia Faculty of Chemical Engineering aud Techology Department of Measurement and Automatic Process Control University of Zagreb Zagreb Croatia

An approach to the neural network-based feedforward control of a two-stage heat exchange process is presented. When pressure change occurs in the distillation column, the disturbance causes a variation of material balance that produces undesirable material and heat imbalance. The task is fulfilled first by developing a mathematical model in a traditional way, followed by the implementation of a neural network multilayer feedforward-based controller. The dynamics and unsteady state are investigated.

关键词： Neural networks Feedforward neural networks Temperature control Manipulator dynamics Feedback control Three-term control Databases Convergence Liquids Spirals

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Catalytic hydrogenation of aromatic nitro compound in a micro-reactor

Catalytic hydrogenation of aromatic nitro compound in a micr...

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Topical Conference on Applications of Micro-Reactor engineering 2007, Held at the 2007 AIChE Spring National Meeting

作者： Lawal, Adeniyi Tadepalli, Sunitha Muslehiddinoglu, Jale Kientzler, Donald New Jersey Center for Microchemical Systems Dept. of Chemical Biomedical and Materials engineering Stevens Institute of Technology Castle Point HobokenNJ United States Process R and D Bristol-Myers Squibb Company One Squibb Drive New BrunswickNJ United States

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Optimal model-based production planning for refinery operations

Optimal model-based production planning for refinery operati...

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2008 AIChE Annual Meeting, AIChE 100

作者： Alattas, Abdulrahman M. Grossmann, Ignacio E. Palou-Rivera, Ignasi Chemical Engineering Carnegie Mellon University 5000 Forbes Ave. Pittsburgh PA 15213 United States Center for Advanced Process Decision-making Dept. of Chemical Engineering Carnegie Mellon University 5000 Forbes Avenue Pittsburgh PA 15213 United States Refining Technology BP Products North America Inc. 150 West Warrenwille Road Naperville IL 60563-8460 United States

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Kinetic study of catalytic hydrogenation of O-nitroanisole to O-anisidine in a microchannel reactor

Kinetic study of catalytic hydrogenation of O-nitroanisole t...

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Topical Conference on Applications of Micro-Reactor engineering 2006, Held at the 2006 AIChE Spring National Meeting

作者： Tadepalli, Sunitha Halder, Raghu Muslehiddinoglu, Jale Kientzler, Donald Lawal, Adeniyi Dept. of Chemical Biomedical and Materials Engineering Stevens Institute of Technology New Jersey Center for Microchemical Systems Castle Point HobokenNJ07030 United States Process R and D Bristol-Myers Squibb Company One Squibb Drive New BrunswickNJ08903 United States

ISBN: (纸本)9781604235258

Hydrogenation reactions are ubiquitous in the fine chemicals and pharmaceutical industries. The hydrogenation of o-nitroanisole to o-anisidine in methanol was selected as a model three-phase reaction for kinetics study in a packed-bed microchannel reactor using Pd metal supported on zeolite as a catalyst. The kinetics of three-phase hydrogenation reactions in conventional slurry or batch reactors is often limited by mass transfer of hydrogen through the liquid due to the limited solubility of hydrogen in organic substrates and solvents. These reactions are also highly exothermic, therefore adequate temperature control is of primary importance to reduce side reactions and to prevent thermal runaway conditions. The use of a microchannel reactor for such reactions provides improved mass and heat transfer rates which may ensure that the reaction operates close to intrinsic kinetics. In the present study, the rate data in the intrinsic kinetic regime were analyzed and found to be well represented by L-H type rate equations. Kinetic experiments were also conducted in a semi-batch reactor under similar reaction conditions as the microchannel reactor. The performance of the packed bed microchannel reactor was compared to that of the semi-batch reactor by evaluating the mass transfer resistance in each system.

关键词： Hydrogen

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State Estimation of Baker's Yeast Fed-Batch Cultivation by Extended Kalman Filter Using Alternative Models 1

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IFAC Proceedings Volumes 1998年第11期31卷 601-606页

作者： P. Hrnčiřík J. Náhlík V. Havlena Dept. of Computing and Control Engineering Institute of Chemical Technology Prague Czech Republic Trnka Laboratory for Automatic Control Czech Technical University Prague and Honeywell Technology Center Prague Czech Republic

The implementation of a new estimation method with alternative process models for the state estimation of the baker’s yeast fermentation is presented. Some of the implementation issues are discussed using the data ob... 详细信息

关键词： Estimation Extended Kalman Filter Fermentation processes Nonlinear model

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