We report the design of an autonomous sensing device, which employs a thermotropic nematic liquid crystal (LC) to conduct chemical or biological sensing tasks. The development of highly reproducible methods to create ...
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To investigate the local environment's effect on the lifetime and quantum yield of extended polymer chains in the absence of intra-and interchain aggregation, short, rodlike polymers of poly(2,5-di-n-octyloxy-1,4-...
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The present study shows that double-stranded RNA-dependent protein kinase (PKR) regulates the protein expression level and phosphorylation of Bcl-2 and plays an anti-apoptotic role in human hepatocellular carcinoma ce...
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The present study shows that double-stranded RNA-dependent protein kinase (PKR) regulates the protein expression level and phosphorylation of Bcl-2 and plays an anti-apoptotic role in human hepatocellular carcinoma cells (HepG2). In various types of cells, saturated free fatty acids (FFAs), such as palmitate, have been shown to induce cellular apoptosis by several mechanisms. Palmitate down-regulates the activity of PKR and thereby decreases the level of Bcl-2 protein, mediated in part by reduced activation of the NF-kB transcription factor. In addition to the level of Bcl-2 protein, the phosphorylation of Bcl-2 at different amino acid residues, such as Ser70 and Ser87, is also important in regulating cellular apoptosis. The decrease in the phosphorylation of Bcl-2 at Ser70 upon exposure to palmitate is mediated by inhibition of PKR and possibly by c-Jun N-terminal kinase (JNK), whereas the phosphorylation of Bcl-2 at Ser87 is unaffected by palmitate or PKR. In summary, PKR mediates the regulation of the protein level and the phosphorylation status of Bcl-2, providing a novel mechanism of palmitate-induced apoptosis in HepG2 cells.
The setting rates of inks on paper influence the printing operation and the quality of the final product. While much work has been reported on the effect of the coating structure on setting rates, much less work has b...
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The setting rates of inks on paper influence the printing operation and the quality of the final product. While much work has been reported on the effect of the coating structure on setting rates, much less work has been done understanding the ink parameters, especially the influence of emulsification. A series of four papers were tested with three inks. The inks were characterized in terms of rheology and their filtration behavior. The filtration rate is used to obtain a permeability value of the ink filtercake. The final print ink density and gloss when printed on paper are reported as well as tack dynamics. The value of the maximum tack was found to depend upon the smoothness of the paper tested and not as much as on the type of ink. The dynamics and magnitude of the tack test depended on the ink viscosity, but viscosity alone does not explain the results. The measured ink filtercake permeabilities are different between the ink types by a factor of two. The setting rate is found to mostly be a function of the viscosity of the oil used in the ink, and not as much a function of the pigment and resin system.
In this article, surface and interface properties of I-D ZnO nanostrutcures from the fundamental optical properties of a single ZnO nanorod to the application in photovoltaics will be presented. In the first part, opt...
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The structure and phase behaviour of PP/POSS nanocomposites obtained by reactive blending of maleic anhydride grafted PP and amino functionalized POSS, have been investigated. SEM, EDS, WAXS and DSC analyses showed ma...
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The structure and phase behaviour of PP/POSS nanocomposites obtained by reactive blending of maleic anhydride grafted PP and amino functionalized POSS, have been investigated. SEM, EDS, WAXS and DSC analyses showed marked changes in the crystallization behaviour and properties of the samples supporting a molecular dispersion of the filler in the polymer matrix.
The use of Pd coatings on multiple InN nanobelts is shown to enhance their sensitivity for hydrogen sensing at hundreds of ppm level at 25 °C. Without the metal coating to catalyze dissociation of the hydrogen mo...
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