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11th IEEE International Conference on Data Mining, ICDM 2011

作者： Hu, Po Huang, Minlie Xu, Peng Li, Weichang Usadi, Adam K. Zhu, Xiaoyan Department of Computer Science and Technology State Key Laboratory on Intelligent Technology and Systems Tsinghua University Beijing China ExxonMobil Research and Engineering Company NJ United States

ISBN: (纸本)9780769544083

Though news readers can easily access a large number of news articles from the Internet, they can be overwhelmed by the quantity of information available, making it hard to get a concise, global picture of a news topic. In this paper we propose a novel method to address this problem. Given a set of articles for a given news topic, the proposed method models theme variation through time and identifies the breakpoints, which are time points when decisive changes occur. For each breakpoint, a brief summary is automatically constructed based on articles associated with the particular time point. Summaries are then ordered chronologically to form a timeline overview of the news topic. In this fashion, readers can easily track various news topics efficiently. We have conducted experiments on 15 popular topics in 2010. Empirical experiments show the effectiveness of our approach and its advantages over other approaches. © 2011 IEEE.

关键词： Data mining

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Time-domain receiving properties of a multimode cylindrical waveguide antenna

Time-domain receiving properties of a multimode cylindrical ...

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作者： Lager, Ioan E. De Hoop, Adrianus T. Delft University of Technology Faculty of Electrical Engineering Mathematics and Computer Science Department of Microwave Technology and Systems for Radar Mekelweg 4 2628 CD Delft Netherlands Delft University of Technology Faculty of Electrical Engineering Mathematics and Computer Science Laboratory of Electromagnetic Research Mekelweg 4 2628 CD Delft Netherlands

ISBN: (纸本)9788882020743

The time-domain receiving properties of a multi-mode cylindrical waveguide antenna are investigated. The configurational properties of the antenna are characterized by the time-domain scattering matrix that interrelates the time-domain amplitudes of the axial modal constituents traveling towards and away from the radiating aperture of the waveguide, which is taken as their reference plane. The excitation of the system by an incident field is expressed as an excitation integral over the aperture that results from the application of the pertaining time-domain Lorentz reciprocity relation of the time-convolution type. Numerical results illustrate the complexity of the changes in pulse shape (with the associated loss of signal integrity) that occur upon the coupling of the incident wave to the different modal constituents. © 2011 EurAAP.

关键词： Circular waveguides

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MEMS-based handheld single-axis confocal microscope design and experiment

MEMS-based handheld single-axis confocal microscope design a...

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International Conference on electrical engineering/Electronics, computer, Telecommunications and Information Technology

作者： Chantakien, Techaniti Raphisak, Pisut Kumazawa, Itsuo Piyawattanametha, Wibool Department of Electrical Engineering Faculty of Engineering Kasetsart University Thailand Imaging Science and Engineering Laboratory Tokyo Institute of Technology Japan Photonics Laboratory National Electronics and Computer Technology and Advanced Imaging Research Center Chulalongkorn University Thailand

ISBN: (纸本)9781457704246

We demonstrate an optical configuration of MEMS based a single-axis confocal microscope imaging setup with 12.7 millimeters diameter commercial lenses. The configuration deploys lens models of optical design software, ZEMAX, to predict optical performance of the actual imaging setup. With this optical design, the maximum field of view is 150 μm x 30 μm with 11.96 μm transverse resolutions and 1.98 mm axial resolution. © 2011 IEEE.

关键词： Microscopes

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A 64-Channel Neural Signal Processor/Compressor Based on Haar Wavelet Transform

A 64-Channel Neural Signal Processor/Compressor Based on Haa...

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Annual International Conference of the IEEE engineering in Medicine and Biology Society

作者： Mohammad Ali Shaeri Amir M. Sodagar Hamid Abrishami-Moghaddam Research Laboratory for Integrated Circuits and Systems (ICAS) Department of Electrical and Computer Engineering K.N. Toosi University of Technology Department of Electrical and Computer Engineering K.N. Toosi University of Technology

ISBN: (纸本)9781424441211

A signal processor/compressor dedicated to implantable neural recording microsystems is presented. Signal compression is performed based on Haar wavelet. It is shown in this paper that, compared to other mathematical transforms already used for this purpose, compression of neural signals using this type of wavelet transform can be of almost the same quality, while demanding less circuit complexity and smaller silicon area. Designed in a 0.13-μm standard CMOS process, the 64-channel 8-bit signal processor reported in this paper occupies 113μm×110μm of silicon area. It operates under a 1.8-V supply voltage at a master clock frequency of 3.2MHz.

关键词： wavelet transforms signal compression circuit complexity supply voltage signal processor reference clock paper 8-bit Silicon Microelectromechanical devices

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282

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Cytokine 2013年第3期63卷 310-310页

作者： Elia D. Tait Wojno Mario Noti Brian S. Kim Mark C. Siracusa Paul R. Giacomin Meera G. Nair Alain J. Benitez Kathryn R. Ruymann Amanda B. Muir David A. Hill Kudakwashe R. Chikwava Amin E. Moghaddam Quentin J. Sattentau Aneesh Alex Chao Zhou Paul Menard-Katcher Masato Kubo Kazushige Obata-Ninomiya Hajime Karasuyama Michael R. Comeau David Artis Department of Microbiology University of Pennsylvania Philadelphia PA USA Institute for Immunology Perelman School of Medicine University of Pennsylvania Philadelphia PA USA Queensland Tropical Health Alliance and School of Public Health and Tropical Medicine James Cook University Cairns Australia Division of Gastroenterology Hepatology and Nutrition Children’s Hospital of Philadelphia Philadelphia PA USA Department of Pediatrics Division of Allergy and Immunology Children’s Hospital of Philadelphia Philadelphia PA USA Department of Pathology and Laboratory Medicine Children’s Hospital of Philadelphia Philadelphia PA USA The Sir William Dunn School of Pathology The University of Oxford Oxford UK Department of Electrical and Computer Engineering Lehigh University Bethlehem PA USA Center for Photonics and Nanoelectronics Lehigh University BethlehemPA USA Bioengineering Program Lehigh University Bethlehem PA USA Division of Gastroenterology Hospital of the University of Pennsylvania Philadelphia PA USA Laboratory for Signal Network Research Center for Allergy and Immunology RIKEN Yokohama Institute Yokohama Japan Division of Molecular Pathology Research Institute for Biological Science Tokyo University of Science Chiba Japan Department of Immune Regulation Tokyo Medical and Dental University Graduate School Tokyo Japan JST CREST Tokyo Medical and Dental University Graduate School Tokyo Japan Inflammation Research Amgen Inc. Seattle WA USA Department of Pathobiology School of Veterinary Medicine University of Pennsylvania Philadelphia PA USA

Eosinophilic esophagitis (EoE) is a food allergy-associated disease characterized by esophageal eosinophilia and associated inflammation. EoE has become increasingly common in industrialized countries. However, current management strategies, such as treatment with swallowed steroids and dietary restrictions, are nonspecific or negatively impact the quality of life of EoE patients. In addition, use of more specific therapies that target immunoglobulin E (IgE) and interleukin (IL)-5 have been largely unsuccessful in ameliorating EoE. Thus, there is an urgent need to identify novel, specific immunological pathways that underlie the pathogenesis of EoE that could be targeted to treat this disease. Recently, a genome-wide association study identified that EoE is associated with a gain-of-function polymorphism in the gene that encodes thymic stromal lymphopoietin (TSLP). TSLP is an IL-7 family member cytokine that promotes allergic inflammation by eliciting T helper type 2 cytokine responses, IgE production, and the expansion of a distinct population of basophils . However, whether TSLP directly promotes allergic inflammation in the esophagus and the mechanisms by which TSLP might contribute to the pathogenesis of EoE remain unknown. Here, we describe a new murine model of experimental EoE-like disease that was used to investigate the role of TSLP in allergic inflammation of the esophagus. Murine experimental EoE-like disease developed independently of IgE but was dependent on TSLP-elicited basophils. Critically, therapeutic antibody-mediated neutralization of TSLP or depletion of basophil populations ameliorated established EoE-like disease in mice. Finally, elevated TSLP levels and exaggerated basophil responses were observed in esophageal biopsies from EoE patients, and a gain-of-function polymorphism in TSLP correlated with increased basophil responses in patients with EoE. Together, these data indicate that TSLP-elicited basophil responses may play a key role in medi

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WOX5-IAA17 feedback circuit mediated cellular auxin response is crucial for Arabidopsis root patterning

WOX5-IAA17 feedback circuit mediated cellular auxin response...

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2012全国植物生物学大会

作者： Krzysztof Wabnik Zhaojun Ding Huiyu Tian Hanbing Li Stephan Pollmann Steffen Vanneste Willy Govaerts Jakub Rol(c)ík Markus Geisler Ji(r)í Friml Department of Plant Systems Biology VIB and Department of Plant Biotechnology and GeneticsGhent University B-9052 Gent Belgium Department of Biochemistry University of Missouri Columbia MO USA Laboratory of Growth Regulators Centre of the Region Haná for Biotechnological and Agricultural Research and Faculty of Science Palack(y) University 78371 Olomouc Czech Republic The Key Laboratory of Plant Cell Engineering and Germplasm Innovation Ministry of EducationSchool of Life Sciences Shandong University Shanda Nanlu 27 Jinan 250100 China Department of Applied Mathematics and Computer Science Ghent University 9000 Gent Belgium Department of Biology Plant Biology University of Fribourg 1700 Fribourg Switzerland Ruhr-Universit(a)t Bochum Lehrstuhl für Pflanzenphysiologie 44801 Bochum Germany

In plants, the patterning of root meristem requires a gradient-guided auxin maximum that depends on the concerted action of polar auxin transport, auxin biosnythesis and intracellular auxin homeostasis.

关键词： WOX5 auxin IAA17/AXR3 root patterning computer simulation

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Resilient subclass discriminant analysis with application to prelens tear film interferometry

Resilient subclass discriminant analysis with application to...

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Lecture Notes in computer science

作者： Boyer, Kim L. Wu, Dijia Signal Analysis and Machine Perception Laboratory Department of Electrical Computer and Systems Engineering Rensselaer Polytechnic Institute Troy NY United States Siemens Corporate Research Princeton NJ United States

ISBN: (纸本)9783642215865

The study of tear film thickness and breakup has important implications for understanding tear physiology and dynamics. We have developed a complete end-to-end automated system for robust and accurate measurements of the tear film thickness from interferometric video as a function of position and time (following a blink). This paper will primarily address the problem of identifying dry regions on the surface of the contact lens, which is one of the four major components of the system. (The others are motion stabilization, image normalization, and phase demodulation to infer absolute thickness and map the surface. To address the challenging wet/dry segmentation problem, we propose a new Gaussian clustering method for feature extraction in high dimensional spaces. Each class is modeled as a mixture of Gaussians, clustered using Expectation-Maximization in the lower-dimensional Fisher's discriminant space. We show that this approach adapts to a wide range of distributions and is insensitive to training sample size. We present experimental results on the real-world problem of identifying regions of breakup (drying) of the prelens tear film from narrowband interferometry for contact lens wearers in vivo. © 2011 Springer-Verlag Berlin Heidelberg.

关键词： Feature extraction

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Design of Double Layer Printed Spiral Coils for Wirelessly-Powered Biomedical Implants

Design of Double Layer Printed Spiral Coils for Wirelessly-P...

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Annual International Conference of the IEEE engineering in Medicine and Biology Society

作者： Ehsan Ashoori Farzad Asgarian Amir M. Sodagar Euisik Yoon Research Laboratory for Integrated Circuits and Systems (ICAS) Electrical & Computer Eng. Dept K.N. Toosi University of Technology Research Laboratory for Integrated Circuits and Systems (ICAS) Electrical & Computer Eng. Dept. K.N. Toosi University of Technology Center for Wireless Integrated Microsystems Department of Electrical Engineering and Computer Science University of Michigan

ISBN: (纸本)9781424441211

In this paper employing double layer printed spiral coils (PSCs) is proposed for wireless power transmission in implantable biomedical applications. Detailed modeling of this type of PSCs is presented. Both calculations and measurements of fabricated double layer PSCs indicate that this structure can decrease the size of typical single layer PSCs without any change in the most important parameters of the coils, such as quality factor. Also, it is shown that with equal PSC dimensions and design parameters, double layer PSCs achieve significantly higher inductances and quality factors. Ultimately, a pair of double layer PSCs with a distance of 5 mm in air is used in an inductive link. The power transfer efficiency of this link is about 79.8% with a carrier frequency of 5 MHz and coupling coefficient of 0.189.

关键词： Double layer helical coil Quality factor TRANSFER EFFICIENCY Implants and Prostheses CARRIER FREQUENCY biomedical

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Two-color-laser-driven direct electron acceleration in infinite vacuum

Two-color-laser-driven direct electron acceleration in infin...

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作者： Wong, Liang Jie Kartner, Franz X. Department of Electrical Engineering and Computer Science Research Laboratory of Electronics Massachusetts Institute of Technology 77 Massachusetts Avenue Cambridge MA 02139 United States

We propose a scheme that uses a two-color pulsed radially-polarized laser beam to achieve electron acceleration exceeding 90% of the theoretical energy gain limit, over twice of what is possible with a one-color beam.... 详细信息

ISBN: (纸本)9781557529107

关键词： Color

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Femtosecond Time Domain Techniques for Characterization of Linear and Nonlinear Optical Properties in GaAs Waveguides

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MRS Online Proceedings Library 2011年第1期167卷 51-60页

作者： K. K. Anderson M. J. Lagasse H. A. Haus J. G. Fujimoto Department of Electrical Engineering and Computer Science and Research Laboratory of Electronics Massachusetts Institute of Technology Cambridge USA

Femtosecond time domain measurements can provide a powerful approach for characterizing both the nonlinear as well as linear optical properties of waveguide devices. We describe a new time division interferometry technique to perform direct measurements of the nonresonant nonlinear index of refraction in AIGaAs waveguides. In addition, femtosecond time of flight measurements permit linear properties such as absorption and dispersion to be characterized using time domain techniques. These techniques permit a comprehensive characterization of linear and nonlinear waveguide properties.

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