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SCDetector: Software Functional Clone Detection Based on Semantic Tokens Analysis

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SCDetector: Software Functional Clone Detection Based on Sem...

IEEE International Conference on Automated Software Engineering (ASE)

作者： Yueming Wu Deqing Zou Shihan Dou Siru Yang Wei Yang Feng Cheng Hong Liang Hai Jin National Engineering Research Center for Big Data Technology and System Services Computing Technology and System Lab Hubei Engineering Research Center on Big Data Security HUST Wuhan China Shenzhen HUST Research Institute Shenzhen China School of Cyber Science and Engineering HUST Wuhan China School of Computer Science and Technology HUST Wuhan China University of Texas at Dallas United States

ISBN: (数字)9781450367684

ISBN: (纸本)9781728172811

Code clone detection is to find out code fragments with similar functionalities, which has been more and more important in software engineering. Many approaches have been proposed to detect code clones, in which token-based methods are the most scalable but cannot handle semantic clones because of the lack of consideration of program semantics. To address the issue, researchers conduct program analysis to distill the program semantics into a graph representation and detect clones by matching the graphs. However, such approaches suffer from low scalability since graph matching is typically time-consuming. In this paper, we propose SCDetector to combine the scalability of token-based methods with the accuracy of graph-based methods for software functional clone detection. Given a function source code, we first extract the control flow graph by static analysis. Instead of using traditional heavyweight graph matching, we treat the graph as a social network and apply social-network-centrality analysis to dig out the centrality of each basic block. Then we assign the centrality to each token in a basic block and sum the centrality ofthe same token in different basic blocks. By this, a graph is turned into certain tokens with graph details (i.e., centrality), called semantic tokens. Finally, these semantic tokens are fed into a Siamese architecture neural network to train a code clone detector. We evaluate SCDetector on two large datasets of functionally similar code. Experimental results indicate that our system is superior to four state-of-the-art methods (i.e., SourcererCC, Deckard, RtvNN, and ASTNN) and the time cost of SCDetector is 14 times less than a traditional graph-based method (i.e., CCSharp) on detecting semantic clones.

关键词： Scalability Semantics Cloning Detectors Transforms Static analysis Software engineering

Kurdish Handwritten Character Recognition using Deep Learning Techniques

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arXiv 2022年

作者： Ahmed, Rebin M. Rashid, Tarik A. Fattah, Polla Alsadoon, Abeer Bacanin, Nebojsa Mirjalili, Seyedali Vimal, S. Chhabra, Amit IT Department Faculty of Applied Science Tishk International University Erbil Iraq Computer Science and Engineering Department University of Kurdistan Hewler Erbil Iraq Software and Informatics Engineering Salahaddin University-Erbil- Erbil Iraq School of Computing and Mathematics Charles Sturt University Sydney Australia Sydney Australia Singidunum University Belgrade Serbia Centre for Artificial Intelligence Research and Optimisation Torrens University Australia Yonsei Frontier Lab Yonsei University Seoul Korea Republic of Department of Artificial Intelligence and Data Science Ramco Institute of Technology North Venganallur Village Virudhunagar District Tamilnadu Rajapalayam626 117 India Department of Computer Engineering and Technology Guru Nanak Dev University Amritsar India

Handwriting recognition is one of the active and challenging areas of research in the field of image processing and pattern recognition. It has many applications that include: a reading aid for visual impairment, automated reading and processing for bank checks, making any handwritten document searchable, and converting them into structural text form, etc. Moreover, high accuracy rates have been recorded by handwriting recognition systems for English, Chinese Arabic, Persian, and many other languages. Yet there is no such system available for offline Kurdish handwriting recognition. In this paper, an attempt is made to design and develop a model that can recognize handwritten characters for Kurdish alphabets using deep learning techniques. Kurdish (Sorani) contains 34 characters and mainly employs an Arabic\Persian based script with modified alphabets. In this work, a Deep Convolutional Neural Network model is employed that has shown exemplary performance in handwriting recognition systems. Then, a comprehensive dataset was created for handwritten Kurdish characters, which contains more than 40 thousand images. The created dataset has been used for training the Deep Convolutional Neural Network model for classification and recognition tasks. In the proposed system, the experimental results show an acceptable recognition level. The testing results reported a 96% accuracy rate, and training accuracy reported a 97% accuracy rate. From the experimental results, it is clear that the proposed deep learning model is performing well and is comparable to the similar model of other languages' handwriting recognition systems. © 2022, CC BY.

关键词： Convolutional neural networks

N-Docker: A NVM-HDD Hybrid Docker Storage Framework to Improve Docker Performance 16th

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N-Docker: A NVM-HDD Hybrid Docker Storage Framework to Impro...

16th IFIP WG 10.3 International Conference on Network and Parallel computing, NPC 2019

作者： Gu, Lin Tang, Qizhi Wu, Song Jin, Hai Zhang, Yingxi Shi, Guoqiang Lin, Tingyu Rao, Jia National Engineering Research Center for Big Data Technology and System Services Computing Technology and System Lab Cluster and Grid Computing Lab School of Computer Science and Technology Huazhong University of Science and Technology Wuhan430074 China State Key Laboratory of Intelligent Manufacturing System Technology Beijing100854 China The University of Texas at Arlington ArlingtonTX76019 United States

ISBN: (纸本)9783030307080

Docker has been widely adopted in production environment, but unfortunately deployment and cold-start of container are limited by the low speed of disk. The emerging non-volatile memory (NVM) technology, which has high speed and can store data permanently, brings a new chance to accelerate the deployment and cold-start of container. However, it is expensive to replace the whole hard disk driver (HDD) with NVM. To achieve the fastest deployment and cold-start with lowest cost, we conduct in-depth analysis on the Top-134 images in Docker Hub and obtain two main insights as: (1) the storing latency of layered image has become the bottleneck of container deployment;(2) only a few image layers are required for container cold-start. Based on these two findings, we propose a NVM-HDD hybrid docker storage framework as N-Docker. It can effectively accelerate container cold-start by detecting the bottleneck layers as well as cold-start required layers and storing them into NVM for faster container startup with limited NVM capacity. Experimental results show that N-Docker can accelerate the container deployment by 1.21X and cold-start by 2.96X. Compared to NVM-Docker, which stores all images into NVM, N-Docker achieves the same performance improvements while reducing the usage of NVM by 88.22%. © 2019, IFIP International Federation for Information Processing.

关键词： Containers

Energy Saving Strategy of Power System Cluster Based on Container Virtualization

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Energy Saving Strategy of Power System Cluster Based on Cont...

IEEE Asia Power and Energy Engineering Conference (APEEC)

作者： Ran Zheng Hao Wang Hai Jin Dechao Xu Yong Chen Xiaomeng Li Yufei Rao Zhenan Zhang National Engineering Research Center for Big Data Technology and System Services Computing Technology and System Lab Cluster and Grid Computing Lab School of Computer Science and Technology Huazhong University of Science and Technology Wuhan China State Key Laboratory of Power Grid Safety and Energy Conservation China Electric Power Research Institute Haidian District Beijing China State Grid Henan Electric Power Company Electric Power Research Institute Zhengzhou China

ISBN: (数字)9781728167824

ISBN: (纸本)9781728167831

With the continuous development of power grids, the scale of supercomputing clusters has also gradually increased to carry a large number of power system simulation calculations, and the problem of high energy consumption has appeared. To solve this problem, we propose a container virtualization-based supercomputing cluster for power system. We analyze the impact of containers on power simulation calculations and compare the energy consumption effects of various container scheduling and migration algorithms on clusters. Experiments show that compared to virtual machines with hypervisor, which consumes massive resources and reduces performances by 28.4%, the performance degradation of container on power simulation calculation is 1.3%, which can be ignored. The energy consumption of load-concentration or resource-and-load-balance container scheduling algorithms is up to 4.0% lower and at least 2.2% lower than other algorithms. In container migration, the method combining autoregressive model with most-correlation and resource-andload-balance algorithms is better than other methods, which not only minimizes energy consumption, but also has lowest number of migrations and SLA violations. Experiments verify the feasibility and advantages of container migration in power system computing clusters.

关键词：

Assessing Trustworthy AI in Times of COVID-19: Deep Learning for Predicting a Multiregional Score Conveying the Degree of Lung Compromise in COVID-19 Patients

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IEEE Transactions on Technology and Society

IEEE Transactions on Technology and Society 2022年第4期3卷 272-289页

作者： Allahabadi, Himanshi Amann, Julia Balot, Isabelle Beretta, Andrea Binkley, Charles Bozenhard, Jonas Bruneault, Frederick Brusseau, James Candemir, Sema Cappellini, Luca Alessandro Chakraborty, Subrata Cherciu, Nicoleta Cociancig, Christina Coffee, Megan Ek, Irene Espinosa-Leal, Leonardo Farina, Davide Fieux-Castagnet, Genevieve Frauenfelder, Thomas Gallucci, Alessio Giuliani, Guya Golda, Adam Van Halem, Irmhild Hildt, Elisabeth Holm, Sune Kararigas, Georgios Krier, Sebastien A. Kuhne, Ulrich Lizzi, Francesca Madai, Vince I. Markus, Aniek F. Masis, Serg Mathez, Emilie Wiinblad Mureddu, Francesco Neri, Emanuele Osika, Walter Ozols, Matiss Panigutti, Cecilia Parent, Brendan Pratesi, Francesca Moreno-Sanchez, Pedro A. Sartor, Giovanni Savardi, Mattia Signoroni, Alberto Sormunen, Hanna-Maria Spezzatti, Andy Srivastava, Adarsh Stephansen, Annette F. Theng, Lau Bee Tithi, Jesmin Jahan Tuominen, Jarno Umbrello, Steven Vaccher, Filippo Vetter, Dennis Westerlund, Magnus Wurth, Renee Zicari, Roberto V. Ey Netherlands Enterprise Intelligence Department Amsterdam1083 HP Netherlands Eth Zurich Health Ethics and Policy Lab Department of Health Sciences and Technology Zürich8092 Switzerland Center for Diplomatic and Strategic Studies Postgraduate Studies in Diplomacy and International Relations Paris75015 France Pisa56124 Italy Hackensack Meridian Health Bioethics Center EdisonNJ08820 United States University of Oxford Faculty of Philosophy OxfordOX2 6GG United Kingdom Collège André- Laurendeau Philosophie Department MontrealQCH8N 2J4 Canada Université du Québec À Montréal École des Médias MontrealQCH2L 2C4 Canada Pace University Philosophy Department New YorkNY10038 United States The Ohio State University Wexner Medical Center Department of Radiology ColumbusOH43210 United States Humanitas Research Hospital Department of Radiology Milan20089 Italy Humanitas University Department of Biomedical Sciences Milan20089 Italy University of New England Faculty of Science Agriculture Business and Law ArmidaleNSW2351 Australia University of Technology Sydney Faculty of Engineering and Information Technology SydneyNSW2007 Australia Scuola Superiore Sant'Anna European Centre of Excellence on the Regulation of Robotics and Ai Pisa56127 Italy University of Bremen Group of Computer Architecture Bremen28359 Germany New York University Grossman School of Medicine Division of Infectious Diseases and Immunology Department of Medicine New YorkNY10016 United States Digital Institute Ai Research Section Stockholm16731 Sweden Arcada University of Applied Sciences Department of Business Management and Analytics Helsinki00550 Finland University of Brescia Radiological Sciences and Public Health Department of Medical and Surgical Specialties Brescia25121 Italy Sncf Reseau Sa Ethique Groupe La Plaine93418 France Institute of Diagnostic and Interventional Radiology University Hospital Zurich Zürich8091 Switzerland Eindhoven University of Tech

This article's main contributions are twofold: 1) to demonstrate how to apply the general European Union's High-Level Expert Group's (EU HLEG) guidelines for trustworthy AI in practice for the domain of healthcare and 2) to investigate the research question of what does 'trustworthy AI' mean at the time of the COVID-19 pandemic. To this end, we present the results of a post-hoc self-assessment to evaluate the trustworthiness of an AI system for predicting a multiregional score conveying the degree of lung compromise in COVID-19 patients, developed and verified by an interdisciplinary team with members from academia, public hospitals, and industry in time of pandemic. The AI system aims to help radiologists to estimate and communicate the severity of damage in a patient's lung from Chest X-rays. It has been experimentally deployed in the radiology department of the ASST Spedali Civili clinic in Brescia, Italy, since December 2020 during pandemic time. The methodology we have applied for our post-hoc assessment, called Z-Inspection®, uses sociotechnical scenarios to identify ethical, technical, and domain-specific issues in the use of the AI system in the context of the pandemic. © 2020 IEEE.

关键词： COVID-19

Pixel-wise dense detector for image inpainting

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arXiv 2020年

作者： Zhang, Ruisong Quan, Weize Wu, Baoyuan Li, Zhifeng Yan, Dong-Ming National Laboratory of Pattern Recognition Institute of Automation Chinese Academy of Sciences Beijing100190 China School of Artificial Intelligence University of Chinese Academy of Sciences Beijing100049 China School of Data Science Chinese University of Hong Kong Shenzhen Hong Kong Secure Computing Lab of Big Data Shenzhen Research Institute of Big Data China Tencent AI Lab Shenzhen China

Recent GAN-based image inpainting approaches adopt an average strategy to discriminate the generated image and output a scalar, which inevitably lose the position information of visual artifacts. Moreover, the adversarial loss and reconstruction loss (e.g., `1 loss) are combined with tradeoff weights, which are also difficult to tune. In this paper, we propose a novel detection-based generative framework for image inpainting, which adopts the min-max strategy in an adversarial process. The generator follows an encoder-decoder architecture to fill the missing regions, and the detector using weakly supervised learning localizes the position of artifacts in a pixel-wise manner. Such position information makes the generator pay attention to artifacts and further enhance them. More importantly, we explicitly insert the output of the detector into the reconstruction loss with a weighting criterion, which balances the weight of the adversarial loss and reconstruction loss automatically rather than manual operation. Experiments on multiple public datasets show the superior performance of the proposed framework. The source code is available at https://***/Evergrow/GDN_Inpainting. Copyright © 2020, The Authors. All rights reserved.

关键词： Pixels

Neuroimaging epicenters as potential sites of onset of the neuroanatomical pathology in schizophrenia

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science Advances 2024年第24期10卷 eadk6063页

作者： Jiang, Yuchao Palaniyappan, Lena Luo, Cheng Chang, Xiao Zhang, Jie Tang, Yingying Zhang, Tianhong Li, Chunbo Zhou, Enpeng Yu, Xin Li, Wei An, Dongmei Zhou, Dong Huang, Chu-Chung Tsai, Shih-Jen Lin, Ching-Po Cheng, Jingliang Wang, Jijun Yao, Dezhong Cheng, Wei Feng, Jianfeng Institute of Science and Technology for Brain-Inspired Intelligence Fudan University Shanghai China Ministry of Education Shanghai China Douglas Mental Health University Institute Department of Psychiatry McGill University MontréalQC Canada Robarts Research Institute University of Western Ontario LondonON Canada Lawson Health Research Institute LondonON Canada Clinical Hospital of Chengdu Brain Science Institute MOE Key Lab for Neuroinformation School of life Science and Technology University of Electronic Science and Technology of China Chengdu China High-Field Magnetic Resonance Brain Imaging Key Laboratory of Sichuan Province Center for Information in Medicine University of Electronic Science and Technology of China Chengdu China Chinese Academy of Medical Sciences Chengdu China Shanghai Key Laboratory of Psychotic Disorders Shanghai Mental Health Center Shanghai Jiao Tong University School of Medicine Shanghai200030 China Beijing China Department of Neurology West China Hospital Sichuan University Chengdu610041 China School of Psychology and Cognitive Science East China Normal University Shanghai China Shanghai Changning Mental Health Center Shanghai China Department of Psychiatry Taipei Veterans General Hospital Taipei Taiwan Institute of Neuroscience National Yang Ming Chiao Tung University Taipei Taiwan Department of MRI First Affiliated Hospital of Zhengzhou University Zhengzhou China Department of Neurology Huashan Hospital Fudan University Shanghai China Fudan ISTBI—ZJNU Algorithm Centre for Brain-Inspired Intelligence Zhejiang Normal University Jinhua China MOE Frontiers Center for Brain Science Fudan University Shanghai China Zhangjiang Fudan International Innovation Center Shanghai China School of Data Science Fudan University Shanghai China Department of Computer Science University of Warwick CoventryCV 4 7AL United Kingdom

Schizophrenia lacks a clear definition at the neuroanatomical level, capturing the sites of origin and progress of this disorder. Using a network-theory approach called epicenter mapping on cross-sectional magnetic resonance imaging from 1124 individuals with schizophrenia, we identified the most likely "source of origin" of the structural pathology. Our results suggest that the Broca’s area and adjacent frontoinsular cortex may be the epicenters of neuroanatomical pathophysiology in schizophrenia. These epicenters can predict an individual’s response to treatment for psychosis. In addition, cross-diagnostic similarities based on epicenter mapping over of 4000 individuals diagnosed with neurological, neurodevelopmental, or psychiatric disorders appear to be limited. When present, these similarities are restricted to bipolar disorder, major depressive disorder, and obsessive-compulsive disorder. We provide a comprehensive framework linking schizophrenia-specific epicenters to multiple levels of neurobiology, including cognitive processes, neurotransmitter receptors and transporters, and human brain gene expression. Epicenter mapping may be a reliable tool for identifying the potential onset sites of neural pathophysiology in schizophrenia. © 2024 the Authors, some rights reserved

关键词： Mapping

FUTURE-AI: International consensus guideline for trustworthy and deployable artificial intelligence in healthcare

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arXiv 2023年

作者： Lekadir, Karim Feragen, Aasa Fofanah, Abdul Joseph Frangi, Alejandro F. Buyx, Alena Emelie, Anais Lara, Andrea Porras, Antonio R. Chan, An-Wen Navarro, Arcadi Glocker, Ben Botwe, Benard O. Khanal, Bishesh Beger, Brigit Wu, Carol C. Cintas, Celia Langlotz, Curtis P. Rueckert, Daniel Mzurikwao, Deogratias Fotiadis, Dimitrios I. Zhussupov, Doszhan Ferrante, Enzo Meijering, Erik Weicken, Eva González, Fabio A. Asselbergs, Folkert W. Prior, Fred Krestin, Gabriel P. Collins, Gary S. Tegenaw, Geletaw S. Kaissis, Georgios Misuraca, Gianluca Tsakou, Gianna Dwivedi, Girish Kondylakis, Haridimos Jayakody, Harsha Woodruf, Henry C. Mayer, Horst Joachim Aerts, Hugo JWL Walsh, Ian Chouvarda, Ioanna Buvat, Irène Tributsch, Isabell Rekik, Islem Duncan, James Kalpathy-Cramer, Jayashree Zahir, Jihad Park, Jinah Mongan, John Gichoya, Judy W. Schnabel, Julia A. Kushibar, Kaisar Riklund, Katrine Mori, Kensaku Marias, Kostas Amugongo, Lameck M. Fromont, Lauren A. Maier-Hein, Lena Alberich, Leonor Cerdá Rittner, Leticia Phiri, Lighton Marrakchi-Kacem, Linda Donoso-Bach, Lluís Martí-Bonmatí, Luis Cardoso, M. Jorge Bobowicz, Maciej Shabani, Mahsa Tsiknakis, Manolis Zuluaga, Maria A. Bielikova, Maria Fritzsche, Marie-Christine Camacho, Marina Linguraru, Marius George Wenzel, Markus De Bruijne, Marleen Tolsgaard, Martin G. Ghassemi, Marzyeh Ashrafuzzaman, Md Goisauf, Melanie Yaqub, Mohammad Abadía, Mónica Cano Mahmoud, Mukhtar M.E. Elattar, Mustafa Rieke, Nicola Papanikolaou, Nikolaos Lazrak, Noussair Díaz, Oliver Salvado, Olivier Pujol, Oriol Sall, Ousmane Guevara, Pamela Gordebeke, Peter Lambin, Philippe Brown, Pieta Abolmaesumi, Purang Dou, Qi Lu, Qinghua Osuala, Richard Nakasi, Rose Zhou, S. Kevin Napel, Sandy Colantonio, Sara Albarqouni, Shadi Joshi, Smriti Carter, Stacy Klein, Stefan Petersen, Steffen E. Aussó, Susanna Awate, Suyash Raviv, Tammy Riklin Cook, Tessa Mutsvangwa, Tinashe E.M. Rogers, Wendy A. Niessen, Wiro J. Puig-Bosch, Xènia Zeng, Yi Mohammed, Yunusa G. Aquino, Yves Saint James Salahuddin, Zohaib Starmans, Martijn P.A. Department de Matemàtiques i Informàtica Universitat de Barcelona Barcelona Spain Barcelona Spain DTU Compute Technical University of Denmark Kgs Lyngby Denmark Department of Mathematics and Computer Science Faculty of Science and Technology Milton Margai Technical University Freetown Sierra Leone Center for Computational Imaging & Simulation Technologies in Biomedicine Schools of Computing and Medicine University of Leeds Leeds United Kingdom Cardiovascular Science and Electronic Engineering Departments KU Leuven Leuven Belgium Institute of History and Ethics in Medicine Technical University of Munich Munich Germany Faculty of Engineering of Systems Informatics and Sciences of Computing Galileo University Guatemala City Guatemala Department of Biostatistics and Informatics Colorado School of Public Health University of Colorado Anschutz Medical Campus AuroraCO United States Department of Medicine Women’s College Research Institute University of Toronto Toronto Canada Universitat Pompeu Fabra BarcelonaBeta Brain Research Center Barcelona Spain Department of Computing Imperial College London London United Kingdom School of Biomedical & Allied Health Sciences University of Ghana Accra Ghana Department of Midwifery & Radiography School of Health & Psychological Sciences City University of London United Kingdom Kathmandu Nepal European Heart Network Brussels Belgium Department of Thoracic Imaging University of Texas MD Anderson Cancer Center Houston United States IBM Research Africa Nairobi Kenya Departments of Radiology Medicine and Biomedical Data Science Stanford University School of Medicine Stanford United States Institute for AI and Informatics in Medicine Klinikum rechts der Isar Technical University Munich Munich Germany Department of Computing Imperial College London London United Kingdom Muhimbili University of Health and Allied Sciences Dar es Salaam Tanzania United Republic of Ioannina Greece Almaty AI Lab Almaty Kazakhstan

Background: Despite major advances in artificial intelligence (AI) research for healthcare, the deployment and adoption of AI technologies remain limited in clinical practice. In recent years, concerns have been raised about the clinical, technical, ethical and legal risks associated with healthcare AI. To increase adoption in the real world, it is essential that AI technologies are trusted and accepted by patients, clinicians, health organisations and authorities. This paper describes the FUTURE-AI framework as the first international consensus guideline for trustworthy AI in healthcare. Methods: The FUTURE-AI consortium was founded in 2021 and now comprises 117 interdisciplinary experts from 50 countries representing all continents, including AI scientists, clinical researchers, biomedical ethicists, and social scientists. Over a two-year period, the consortium established guiding principles and best practices for trustworthy and deployable AI through an iterative process comprising an in-depth literature review, a modified Delphi survey, and online consensus meetings. Findings: The FUTURE-AI framework was established based on six guiding principles for trustworthy AI in healthcare, i.e. Fairness, Universality, Traceability, Usability, Robustness and Explainability. Through consensus, a set of 30 best practices were defined, addressing technical, clinical, socio-ethical and legal dimensions of trustworthy AI. The recommendations cover the entire lifecycle of healthcare AI, from design, development and validation to regulation, deployment, and monitoring. Interpretation: FUTURE-AI is a structured, risk-informed framework which provides guidance for constructing healthcare AI tools that will be trusted, deployed and adopted in real-world clinical practice. researchers are encouraged to take the recommendations into account in proof-of-concept stages to facilitate future translation towards clinical practice of healthcare AI. Copyright © 2023, The Authors. All rights

关键词： Clinical research

Deep Learning for Brain Age Estimation: A Systematic Review

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arXiv 2022年

作者： Tanveer, M. Ganaie, M.A. Beheshti, Iman Goel, Tripti Ahmad, Nehal Lai, Kuan-Ting Huang, Kaizhu Zhang, Yu-Dong Ser, Javier Del Lin, Chin-Teng Department of Mathematics Indian Institute of Technology Indore Simrol Indore453552 India Department of Robotics University of Michigan Ann ArborMI48109 United States Department of Human Anatomy and Cell Science Rady Faculty of Health Sciences Max Rady College of Medicine University of Manitoba WinnipegMB Canada Biomedical Imaging Lab National Institute of Technology Assam Silchar788010 India Department of Electrical Engineering and Computer Science National Taipei University of Technology Taipei Taiwan Department of Electronic Engineering National Taipei University of Technology Taipei Taiwan Data Science Research Center Duke Kunshan University China School of Computing and Mathematical Sciences University of Leicester United Kingdom Derio48160 Spain Bilbao48013 Spain School of Computer Science Faculty of Engineering and Information Technology University of Technology Sydney Sydney Australia

Over the years, Machine Learning models have been successfully employed on neuroimaging data for accurately predicting brain age. Deviations from the healthy brain aging pattern are associated to the accelerated brain aging and brain abnormalities. Hence, efficient and accurate diagnosis techniques are required for eliciting accurate brain age estimations. Several contributions have been reported in the past for this purpose, resorting to different data-driven modeling methods. Recently, deep neural networks (also referred to as deep learning) have become prevalent in manifold neuroimaging studies, including brain age estimation. In this review we offer a comprehensive analysis of the literature related to the adoption of deep learning for brain age estimation with neuroimaging data. We detail and analyze different deep learning architectures used for this application, pausing at research works published to date quantitatively exploring their application. We also examine different brain age estimation frameworks, comparatively exposing their advantages and weaknesses. Finally, the review concludes with an outlook towards future directions that should be followed by prospective studies. The ultimate goal of this paper is to establish a common and informed reference for newcomers and experienced researchers willing to approach brain age estimation by using deep learning models. Copyright © 2022, The Authors. All rights reserved.

关键词： Deep neural networks