检索结果-内蒙古大学图书馆

High-Performance Thermoelectric α-Ag9Ga1−xTe6Compounds with Ultralow Lattice Thermal Conductivity Originating from Ag9Te2Motifs

引用

Angewandte Chemie 2022年第36期134卷

作者： Yingfei Tang Yimeng Yu Na Zhao Keke Liu Haijie Chen Constantinos C. Stoumpos Yixuan Shi Shuo Chen Lingxiao Yu Jinsong Wu Qingjie Zhang Xianli Su Xinfeng Tang State Key Laboratory of Advanced Technology for Materials Synthesis and Processing Wuhan University of Technology Wuhan 430070 China International School of Materials Science and Engineering Wuhan University of Technology Wuhan 430070 China Contribution: Conceptualization (equal) Data curation (lead) Formal analysis (lead) Investigation (equal) Methodology (equal) Visualization (equal) Writing - original draft (lead) Nanostructure Research Center Wuhan University of Technology Wuhan 430070 China Contribution: Data curation (equal) Software (equal) Visualization (supporting) Contribution: Investigation (equal) Methodology (equal) Contribution: Investigation (equal) Methodology (equal) Visualization (equal) State Key Laboratory for Modification of Chemical Fibers and Polymer Materials Institute of Functional Materials College of Materials Science and Engineering Donghua University Shanghai 201620 China Contribution: Methodology (equal) Visualization (equal) Writing - review & editing (equal) Department of Materials Science and Technology Voutes Campus University of Crete Iraklio Heraklion 70013 Greece Contribution: Methodology (equal) Visualization (equal) Contribution: Investigation (equal) Visualization (equal) Contribution: Conceptualization (equal) Investigation (equal) Contribution: Methodology (equal) Contribution: Conceptualization (equal) Methodology (equal) Contribution: Conceptualization (equal) Investigation (equal) Methodology (equal) Writing - review & editing (equal) Contribution: Conceptualization (equal) Funding acquisition (lead) Methodology (equal) Supervision (equal) Writing - review & editing (equal)

We have determined the complex atomic structure of high-temperature α-Ag 9 GaTe 6 phase with a hexagonal lattice ( P 6 3 mc space group, a = b =8.2766 Å, c =13.4349 Å). The structure has outer [GaTe 4 ] 5− tetrahedrons and inner [Ag 9 Te 2 ] 5+ clusters. All of the Ag ions are disorderly distributed in the lattice. Seven types of the Ag atoms constitute the cage-like [Ag 9 Te 2 ] 5+ clusters. The highly disordered Ag ions vibrate in-harmonically, producing strong coupling between low frequency optical phonons and acoustic phonons. This in conjunction with a low sound velocity of 1354 m s −1 leads to an ultralow thermal conductivity of 0.20 W m −1 K −1 at 673 K. Meanwhile, the deficiency of Ga in Ag 9 Ga 1− x Te 6 compounds effectively optimizes the electronic transport properties. Ag 9 Ga 0.91 Te 6 attains a highest power factor of 0.40 mW m −1 K −2 at 673 K. All these contribute to a much-improved ZT value of 1.13 at 623 K for Ag 9 Ga 0.95 Te 6 , which is 41 % higher than that of the pristine Ag 9 GaTe 6 sample.

关键词： α-Ag9GaTe6 Crystal Structure Ga Deficiency Thermoelectrics Ultralow Lattice Thermal Conductivity

来源：评论

学校读者我要写书评

暂无评论

Fano Resonance in Single-Molecule Junctions

引用

Angewandte Chemie 2022年第40期134卷

作者： Yan Zheng Ping Duan Yu Zhou Chuan Li Dahai Zhou Yaping Wang Li-Chuan Chen Zhiyu Zhu Xiaohui Li Jie Bai Kai Qu Tengyang Gao Jia Shi Junyang Liu Qian-Chong Zhang Zhong-Ning Chen Wenjing Hong State Key Laboratory of Physical Chemistry of Solid Surfaces College of Chemistry and Chemical Engineering and Institute of Artificial Intelligence and Innovation Laboratory for Sciences and Technologies of Energy Materials of Fujian Province (IKKEM) Xiamen University Xiamen 361005 China Contribution: Data curation (lead) Investigation (lead) Writing - review & editing (equal) Contribution: Investigation (equal) Methodology (equal) Writing - original draft (lead) Contribution: Investigation (equal) Methodology (equal) Validation (lead) State Key Laboratory of Structural Chemistry Fujian Institute of Research on the Structure of Matter Chinese Academy of Sciences Fuzhou 350002 China School of Physical Science and Technology Shanghai Tech University Shanghai 201210 China University of Chinese Academy of Sciences Beijing 100049 China Contribution: Investigation (equal) Contribution: Conceptualization (equal) Data curation (equal) Writing - original draft (equal) Contribution: Writing - review & editing (equal) Contribution: Validation (equal) Contribution: Software (equal) Contribution: Methodology (supporting) Contribution: Validation (supporting) Contribution: Software (lead) Contribution: Conceptualization (lead) Funding acquisition (equal) Investigation (lead) Project administration (equal) Supervision (equal) Validation (equal) Writing - review & editing (lead) Contribution: Conceptualization (equal) Funding acquisition (equal) Project administration (equal) Validation (equal) Writing - review & editing (equal) Contribution: Conceptualization (supporting) Funding acquisition (equal) Contribution: Conceptualization (lead) Funding acquisition (lead) Methodology (equal) Project administration (lead) Resources (lead) Software (equal) Supervision (lead) Writing - review & editing (equal)

The Fano resonance in single-molecule junctions could be created by interaction with discrete and continuous molecular orbitals and enables effective electron transport modulation between constructive and destructive interference within a small energy range. However, direct observation of Fano resonance remains unexplored because of the disappearance of discrete orbitals by molecule-electrode coupling. We demonstrated the room-temperature observation of Fano resonance from electrochemical gated single-molecule conductance and current–voltage measurements of a para -carbazole anion junction. Theoretical calculations reveal that the negative charge on the nitrogen atom induces a localized HOMO on the molecular center, creating Fano resonance by interfering with the delocalized LUMO on the molecular backbone. Our findings demonstrate that the Fano resonance in electron transport through single-molecule junctions opens pathways for designs of interference-based electronic devices.

关键词： Charge Transfer Electrochemical Gating Fano Resonance Single-Molecule Junctions

来源：评论

学校读者我要写书评

暂无评论

Solution-Processable Pure-Red Multiple Resonance-induced Thermally Activated Delayed Fluorescence Emitter for Organic Light-Emitting Diode with External Quantum Efficiency over 20 %

引用

Angewandte Chemie 2022年第7期135卷

作者： Xinliang Cai Dr. Yincai Xu Yue Pan Linjie Li Yexuan Pu Dr. Xuming Zhuang Prof. Chenglong Li Prof. Yue Wang State Key Laboratory of Supramolecular Structure and Materials College of Chemistry Jilin University Changchun 130012 P. R. China Contribution: Data curation (lead) Formal analysis (equal) Supervision (equal) Validation (equal) Writing - original draft (lead) Writing - review & editing (equal) Contribution: Conceptualization (equal) Methodology (equal) Writing - original draft (equal) Key Laboratory for Molecular Enzymology and Engineering of Ministry of Education School of Life Science Jilin University Changchun 130012 P. R. China Contribution: Formal analysis (equal) Methodology (equal) Software (equal) Contribution: Formal analysis (equal) Methodology (equal) Jihua Laboratory 28 Huandao South Road Foshan 528200 Guangdong Province P. R. China Contribution: Data curation (equal) Methodology (lead) Software (equal) Visualization (equal) Chongqing Research Institute Jilin University Chongqing 401120 P. R. China Contribution: Conceptualization (lead) Formal analysis (equal) Methodology (equal) Supervision (equal) Visualization (equal) Writing - original draft (equal) Writing - review & editing (equal) Jihua Hengye Electronic Materials CO. LTD. Foshan 528200 Guangdong Province P. R. China Contribution: Supervision (equal) Visualization (equal) Writing - original draft (supporting)

Developing solution-processable red organic light-emitting diodes (OLEDs) with high color purity and efficiency based on multiple resonance thermally activated delayed fluorescence (MR-TADF) is a formidable challenge. Herein, by introducing auxiliary electron donor and acceptor moieties into the highest occupied molecular orbital (HOMO) and lowest unoccupied molecular orbital (LUMO) distributed positions of multiple resonance skeleton simultaneously, an effective strategy to obtain red MR-TADF emitters was represented. The proof-of-the-concept molecule BN-R exhibits a narrowband pure-red emission at 624 nm, with a high luminous efficiency of 94 % and a narrow bandwidth of 46 nm. Notably, the fabricated solution-processable pure-red OLED based on BN-R exhibits a state-of-the-art external quantum efficiency over 20 % with the Commission Internationale de I’Éclairage coordinates of (0.663, 0.337) and a long operational lifetime (LT 50 ) of 1088 hours at an initial luminance of 1000 cd m −2 .

关键词： Multiple Resonance Narrowband Emission Organic Light-Emitting Diodes Solution-Processed Thermally Activated Delayed fluorescence

来源：评论

学校读者我要写书评

暂无评论

THE CALLING(SM) NETWORK - A GLOBAL WIRELESS COMMUNICATION-SYSTEM

引用

INTERNATIONAL JOURNAL OF SATELLITE COMMUNICATIONS 1994年第1期12卷 45-61页

作者： TUCK, EF PATTERSON, DP STUART, JR LAWRENCE, MH Calling Communications Corporation. 1900 West Garvey Ave South. Suite 200 West Covina CA 91790 USA. Chairman of Calling Communications Corporation. He is also the Managing Director of Kinship Venture Management Inc. the general partner of Kinship Partners 11 and a General Partner of Boundary the general partner of The Boundary Fund. As a venture capitalist he has founded or participated in founding several telecommunications companies including Calling Communications Corporation Magellan Systems Corporation manufactures of Global Positioning System receivers Applied Digital Access manufacturer of DS-3 test access and network performance monitoring equipment Endgate Technology Corporation specialists in satellite phased array antennas and Poynting Systems Corporation. now a division of Reliance Corporation manufacturers of fibre optic transport equipment. He was a founder of Kebby Microwave Corporation where he invented the first solid-state. frequency-modulated commercial microwave link system. The company was acquired by ITT Corporation where he rose to the position of V.P. and Technical Director of ITT North America Telecommunications Inc. Subsequently he was V.P. of Marketing and Engineering at American Telecommunications Inc. (ATC). He was founding Director of American Telecom Inc. a joint venture between ATC and Fujitsu and has served on more than 20 boards of directors including those of three public companies. He has authored articles on microwave engineering and telephone signalling and was a contributor to Reference Data For Radio Engineers. He is a graduate of the University of Missouri at Rolla where he was later awarded an honorary Professional degree and serves on its Academy of Electrical Engineering. Mr Tuck is a Senior Member of the IEEE a Fellow of the Institution of Engineers (Australia) a Professional Member of the AIAA and a registered professional engineer in three states. More than 25 years of experience in the telecommunications industry where he has been responsibl

There is a very large demand for basic telephone service in developing nations, and remote parts of industrialized nations, which cannot be met by conventional wireline and cellular systems. This is the world's largest unserved market. We describe a system which uses recent advances in active phased arrays, fast-packet switching technology, adaptive routeing, and light spacecraft technology, in part based on the work of the Jet Propulsion Laboratory and on recently-declassified work done on the Strategic Defense Initiative, to make it possible to address this market with a global telephone network based on a large low-Earth-orbit constellation of identical satellites. A telephone utility can use such a network to provide the same modern basic and enhanced telephone services offered by telephone utilities in the urban centres of fully-industrialized nations. Economies of scale permit capital and operating costs per subscriber low enough to provide a service to all subscribers, regardless of location, at prices comparable to the same services in urban areas of industrialized nations, while generating operating profits great enough to attract the capital needed for its construction. The bandwidth needed to support the capacity needed to gain these economies of scale requires that the system use K(alpha)-band frequencies. This choice of frequencies places unusual constraints on the network design, and in particular forces the use of a large number of satellites. Global demand for basic and enhanced telephone service is great enough to support at least three networks of the size described herein. The volume of advanced components, and services such as launch services, required to construct and replace these networks is sufficient to propel certain industries to market leadership positions in the early 21st Century.

关键词： LOW EARTH ORBIT SATELLITE COMMUNICATIONS FAST PACKET SWITCHING EARTH FIXED CELLS ADAPTIVE ROUTEING LIGHT SPACECRAFT K(A) BAND PHASED-ARRAY ANTENNAS

来源：评论

学校读者我要写书评

暂无评论

Non-symmetric Half-Fused B←N Coordinated Diketopyrrolopyrrole Building Block forn-type Semiconducting Polymers

引用

Angewandte Chemie 2023年第23期135卷

作者： Jinqiu Meng Jiawen Dou Zhaoqiong Zhou Pinyu Chen Nan Luo Dr. Yan Li Liang Luo Prof. Feng He Prof. Hua Geng Prof. Xiangfeng Shao Prof. Hao-Li Zhang Prof. Zitong Liu State Key Laboratory of Applied Organic Chemistry (SKLAOC) Key Laboratory of Special Function Materials and Structure Design College of Chemistry and Chemical Engineering Lanzhou University Lanzhou 730000 China Contribution: Investigation (equal) Validation (equal) Writing - review & editing (supporting) Beijing Key Laboratory for Optical Materials and Photonic Devices Department of Chemistry Capital Normal University Beijing 100048 China Contribution: Investigation (equal) Methodology (equal) Contribution: Data curation (equal) Investigation (supporting) Methodology (supporting) Contribution: Investigation (supporting) Methodology (supporting) Validation (supporting) Guangdong Provincial Key Laboratory of Catalysis Shenzhen Grubbs Institute and Department of Chemistry Southern University of Science and Technology Shenzhen 518055 China Contribution: Investigation (supporting) Validation (supporting) Contribution: Conceptualization (supporting) Data curation (supporting) Investigation (supporting) Methodology (supporting) Software (lead) Writing - review & editing (supporting) Contribution: Conceptualization (supporting) Methodology (supporting) Validation (supporting) Writing - review & editing (supporting) Contribution: Conceptualization (supporting) Project administration (supporting) Writing - review & editing (supporting) Contribution: Conceptualization (lead) Project administration (lead) Supervision (lead) Writing - original draft (lead) Writing - review & editing (lead)

The development of conjugated polymers with high semiconducting performance and high reliability is of great significance for flexible electronics. Herein, we developed a new type of electron-accepting building block; i.e., non-symmetric half-fused B←N coordinated diketopyrrolopyrrole (DPP) ( HBNDPP ), for amorphous conjugated polymers toward flexible electronics. The rigid B←N fusion part of HBNDPP endows the resulting polymers with decent electron transport, while its non-symmetric structure causes the polymer to exhibit multiple conformation isomers with flat torsional potential energies. Thus, it gets packed in an amorphous manner in solid state, ensuring good resistance to bending strain. Combined with hardness and softness, the flexible organic field-effect transistor devices exhibit n -type charge properties with decent mobility, good bending resistance, and good ambient stability. The preliminary study makes this building block a potential candidate for future design of conjugated materials for flexible electronic devices.

关键词： B←N Coordination Conjugated Polymer Diketopyrrolopyrrole Non-Symmetric Chemical Structure n-Type Semiconductor

来源：评论

学校读者我要写书评

暂无评论

A Multifunctional Polymer as an Interfacial Layer for Efficient and Stable Perovskite Solar Cells

引用

Angewandte Chemie 2022年第2期135卷

作者： Bingqian Zhang Chen Chen Xianzhao Wang Xiaofan Du Dachang Liu Xiuhong Sun Zhipeng Li Lianzheng Hao Caiyun Gao Yimeng Li Zhipeng Shao Xiao Wang Prof. Guanglei Cui Prof. Shuping Pang Qingdao Institute of Bioenergy and Bioprocess Technology Chinese Academy of Sciences Qingdao 266101 P. R. China College of Materials Science and Engineering Qingdao University of Science and Technology Qingdao 266042 P. R. China Shandong Energy Institute Qingdao 266101 P. R. China Contribution: Conceptualization (equal) Data curation (lead) Formal analysis (lead) Investigation (lead) Methodology (lead) Project administration (equal) Validation (lead) Visualization (equal) Writing - original draft (lead) Writing - review & editing (equal) Contribution: Data curation (supporting) Formal analysis (supporting) Investigation (supporting) Methodology (supporting) Visualization (supporting) Contribution: Data curation (supporting) Formal analysis (supporting) Investigation (supporting) Resources (equal) Validation (supporting) Contribution: Methodology (supporting) Software (lead) Contribution: Formal analysis (supporting) Methodology (supporting) Resources (supporting) Validation (supporting) Visualization (supporting) Writing - review & editing (supporting) Contribution: Formal analysis (supporting) Investigation (supporting) Validation (supporting) Writing - review & editing (supporting) Contribution: Methodology (supporting) Validation (supporting) Visualization (supporting) Contribution: Investigation (supporting) Methodology (supporting) Validation (supporting) Contribution: Formal analysis (supporting) Resources (supporting) Validation (supporting) Contribution: Investigation (supporting) Validation (supporting) Contribution: Investigation (supporting) Methodology (supporting) Contribution: Conceptualization (equal) Formal analysis (supporting) Funding acquisition (equal) Investigation (supporting) Methodology (supporting) Project administration (equal) Supervision (equal) Validation (equal) Visualization (equal) Writing - review & editing (equal) Contribution: Methodology (supporting) Supervision (supporting) Contribution: Conceptualization (equal) Dat

Metal-cation defects and halogen-anion defects in perovskite films are critical to the efficiency and stability of perovskite solar cells (PSCs). In this work, a random polymer, poly(methyl methacrylate- co -acrylamide) (PMMA-AM), was synthesized to serve as an interfacial passivation layer for synergistically passivating the under-coordinated Pb 2+ and anchor the I - of the [PbI 6 ] 4− octahedron. Additionally, the interfacial PMMA-AM passivation layer cannot be destroyed during the hole transport layer deposition because of its low solubility in chlorobenzene. This passivation leads to an enhancement in the open-circuit voltage from 1.12 to 1.22 V and improved stability in solar cell devices, with the device maintaining 95 % of the initial power conversion efficiency (PCE) over 1000 h of maximum power point tracking. Additionally, a large-area solar cell module was fabricated using this approach, achieving a PCE of 20.64 %.

关键词： Passivation Perovskite Polymer Solar Cells Stability

来源：评论

学校读者我要写书评

暂无评论

MedShapeNet - A Large-Scale dataset of 3D Medical Shapes for Computer Vision

arXiv

引用

arXiv 2023年

作者： Li, Jianning Zhou, Zongwei Yang, Jiancheng Pepe, Antonio Gsaxner, Christina Luijten, Gijs Qu, Chongyu Zhang, Tiezheng Chen, Xiaoxi Li, Wenxuan Wodzinski, Marek Friedrich, Paul Xie, Kangxian Jin, Yuan Ambigapathy, Narmada Nasca, Enrico Solak, Naida Melito, Gian Marco Vu, Viet Duc Memon, Afaque R. Schlachta, Christopher De Ribaupierre, Sandrine Patel, Rajnikant Eagleson, Roy Chen, Xiaojun Mächler, Heinrich Kirschke, Jan Stefan de la Rosa, Ezequiel Christ, Patrick Ferdinand Li, Hongwei Bran Ellis, David G. Aizenberg, Michele R. Gatidis, Sergios Küstner, Thomas Shusharina, Nadya Heller, Nicholas Andrearczyk, Vincent Depeursinge, Adrien Hatt, Mathieu Sekuboyina, Anjany Löffler, Maximilian Liebl, Hans Dorent, Reuben Vercauteren, Tom Shapey, Jonathan Kujawa, Aaron Cornelissen, Stefan Langenhuizen, Patrick Ben-Hamadou, Achraf Rekik, Ahmed Pujades, Sergi Boyer, Edmond Bolelli, Federico Grana, Costantino Lumetti, Luca Salehi, Hamidreza Ma, Jun Zhang, Yao Gharleghi, Ramtin Beier, Susann Sowmya, Arcot Garza-Villarreal, Eduardo A. Balducci, Thania Angeles-Valdez, Diego Souza, Roberto Rittner, Leticia Frayne, Richard Ji, Yuanfeng Ferrari, Vincenzo Chatterjee, Soumick Dubost, Florian Schreiber, Stefanie Mattern, Hendrik Speck, Oliver Haehn, Daniel John, Christoph Nürnberger, Andreas Pedrosa, João Ferreira, Carlos Aresta, Guilherme Cunha, António Campilho, Aurélio Suter, Yannick Garcia, Jose Lalande, Alain Vandenbossche, Vicky Van Oevelen, Aline Duquesne, Kate Mekhzoum, Hamza Vandemeulebroucke, Jef Audenaert, Emmanuel Krebs, Claudia van Leeuwen, Timo Vereecke, Evie Heidemeyer, Hauke Röhrig, Rainer Hölzle, Frank Badeli, Vahid Krieger, Kathrin Gunzer, Matthias Chen, Jianxu van Meegdenburg, Timo Dada, Amin Balzer, Miriam Fragemann, Jana Jonske, Frederic Rempe, Moritz Malorodov, Stanislav Bahnsen, Fin H. Seibold, Constantin Jaus, Alexander Marinov, Zdravko Jaeger, Paul F. Stiefelhagen, Rainer Santos, Ana Sofia Lindo, Mariana Ferreira, André Alves, Victor Kamp, Michael Abourayya, Amr Nensa, Felix Hörst, Fabian Brehmer, Alexander Hein Girardetstraße 2 Essen45131 Germany Graz University of Technology Inffeldgasse 16c Graz8010 Austria Graz Austria The Department of Computer Science Johns Hopkins University Malone Hall 3400 N Charles St BaltimoreMD21218 United States Rte Cantonale Lausanne1015 Switzerland The Department of Measurement and Electronics AGH University of Science and Technology Krakow Poland Sierre Switzerland Department of Biomedical Engineering University of Basel Hegenheimermattweg Allschwil167C CH-4123 Switzerland The Boston College 140 Commonwealth Ave Chestnut HillMA02467 United States University Hospital B7-200 339 Windermere Road LondonN6A 5A5 Canada The Department of Radiology Renji Hospital School of Medicine Shanghai Jiao Tong University Shanghai200240 China The Research Center for Connected Healthcare Big Data ZhejiangLab Zhejiang Hangzhou311121 China The Faculty of Statistics Technical University Dortmund August-Schmidt-Straße 1 Dortmund44227 Germany The Institute of Mechanics Graz University of Technology Kopernikusgasse 24/IV Graz8010 Austria The Institute of Biomedical Manufacturing and Life Quality Engineering State Key Laboratory of Mechanical System and Vibration School of Mechanical Engineering Shanghai Jiao Tong University 800 Dongchuan Road Shanghai200240 China The Department of Cardiac Surgery Medical University Graz Auenbruggerplatz 29 Graz8036 Austria The Department of Diagnostic and Interventional Radiology University Hospital Giessen Justus-Liebig-University Giessen Klinikstraße 33 Giessen35392 Germany The Department of Mechanical Engineering Mehran University of Engineering and Technology Jamshoro Sindh76062 Pakistan The Institute of Medical Robotics Shanghai Jiao Tong University Shanghai China The Geschäftsführender Oberarzt Abteilung für Interventionelle und Diagnostische Neuroradiologie Universitätsklinikum der Technischen Universität München Ismaningerstr. 22 München81675 Germany icometrix Kolonel Be

Prior to the deep learning era, shape was commonly used to describe the objects. Nowadays, state-of-the-art (SOTA) algorithms in medical imaging are predominantly diverging from computer vision, where voxel grids, meshes, point clouds, and implicit surface models are used. This is seen from numerous shape-related publications in premier vision conferences as well as the growing popularity of ShapeNet (about 51,300 models) and Princeton ModelNet (127,915 models). For the medical domain, we present a large collection of anatomical shapes (e.g., bones, organs, vessels) and 3D models of surgical instrument, called MedShapeNet, created to facilitate the translation of data-driven vision algorithms to medical applications and to adapt SOTA vision algorithms to medical problems. As a unique feature, we directly model the majority of shapes on the imaging data of real patients. As of today, MedShapeNet includes 23 datasets with more than 100,000 shapes that are paired with annotations (ground truth). Our data is freely accessible via a web interface and a Python application programming interface (API) and can be used for discriminative, reconstructive, and variational benchmarks as well as various applications in virtual, augmented, or mixed reality, and 3D printing. Exemplary, we present use cases in the fields of classification of brain tumors, skull reconstructions, multi-class anatomy completion, education, and 3D printing. In future, we will extend the data and improve the interfaces. The project pages are: https://***/ and https://***/Jianningli/*** Codes 68T01 © 2023, CC BY.

关键词： Large dataset

来源：评论

学校读者我要写书评

暂无评论

Conferring BiVO4Nanorods with Oxygen Vacancies to Realize Enhanced Sonodynamic Cancer Therapy

引用

Angewandte Chemie 2022年第44期134卷

作者： Dr. Zhuang Yang Dr. Meng Yuan Dr. Bin Liu Dr. Wenying Zhang Dr. Aziz Maleki Prof. Baolin Guo Prof. Ping'an Ma Prof. Ziyong Cheng Prof. Jun Lin State Key Laboratory of Rare Earth Resource Utilization Changchun Institute of Applied Chemistry Changchun 130022 P. R. China School of Applied Chemistry and Engineering University of Science and Technology of China Hefei 230026 P. R. China Contribution: Investigation (lead) Methodology (lead) Resources (lead) Supervision (lead) Writing - original draft (lead) Writing - review & editing (lead) Contribution: Conceptualization (equal) Investigation (equal) Software (lead) Contribution: Formal analysis (supporting) Funding acquisition (supporting) Methodology (supporting) Contribution: Data curation (supporting) Project administration (supporting) Resources (supporting) Zanjan Pharmaceutical Nanotechnology Research Center (ZPNRC) and Department of Pharmaceutical Nanotechnology School of Pharmacy Zanjan University of Medical Sciences Zanjan 45139-56184 Iran Contribution: Methodology (supporting) Resources (supporting) State Key Laboratory for Mechanical Behavior of Materials and Frontier Institute of Science and Technology and Key Laboratory of Shaanxi Province for Craniofacial Precision Medicine Research College of Stomatology Xi'an Jiaotong University Xi'an 710049 P. R. China Contribution: Investigation (supporting) Validation (supporting) Contribution: Formal analysis (supporting) Software (supporting) Visualization (supporting) Guangdong Provincial Key Laboratory of Research and Development of Natural Drugs School of Pharmacy Guangdong Medical University Guangdong Medical University Key Laboratory of Research and Development of New Medical Materials Dongguan 523808 P. R. China Contribution: Validation (lead) Visualization (lead) Writing - original draft (lead) Writing - review & editing (lead) Contribution: Resources (lead) Visualization (lead) Writing - review & editing (lead)

Owing to the high depth of tissue penetration, non-invasiveness, and controllability, ultrasound (US)-mediated sonodynamic therapy (SDT) has shown broad application prospects for tumor treatment. However, the electron-hole separation inefficiency of sonosensitizers and the tumor hypoxia remain two major challenges limiting the effect of SDT. Here, ultrafine photoetched bismuth vanadate (BiVO 4 ) nanorods modified with DSPE-PEG 2000 (PEBVO@PEG NRs) were fabricated to achieve in situ self-supply of oxygen (O 2 ) and reactive oxygen species (ROS) for hypoxic tumor therapy. The photoetching approach could enhance the charge separation by inducing enriched oxygen vacancies on the surface of BiVO 4 , thereby improving the generation efficiency of ROS and O 2 . The PEBVO@PEG overcome the main obstacles of traditional sonosensitizers in the SDT process and show promising sonodynamic therapeutic effects, thus providing new strategies for improving the performance of sonosensitizer and hypoxic tumor elimination.

关键词： Bismuth Vanadate Sonodynamic Therapy Sonosensitizers Surface Oxygen Vacancies Ultrasound

来源：评论

学校读者我要写书评

暂无评论

The need to implement FAIR principles in biomolecular simulations

arXiv

引用

arXiv 2024年

作者： Amaro, R. Åqvist, J. Bahar, I. Battistini, F. Bellaiche, A. Beltran, D. Biggin, P.C. Bonomi, M. Bowman, G.R. Bryce, R. Bussi, G. Carloni, P. Case, D. Cavalli, A. Chang, C.A. Cheatham, T.E. Cheung, M.S. Chipot, C. Chong, L.T. Choudhary, P. Cisneros, G.A. Clementi, C. Collepardo-Guevara, R. Coveney, P. Covino, R. Crawford, T.D. Dal Peraro, M. de Groot, B. Delemotte, L. De Vivo, M. Essex, J. Fraternali, F. Gao, J. Gelpí, J.L. Gervasio, F.L. Gonzalez-Nilo, F.D. Grubmüller, H. Guenza, M.G. Guzman, H.V. Harris, S. Head-Gordon, T. Hernandez, R. Hospital, A. Huang, N. Huang, X. Hummer, G. Iglesias-Fernández, J. Jensen, J.H. Jha, S. Jiao, W. Jorgensen, W.L. Kamerlin, S.C.L. Khalid, S. Laughton, C. Levitt, M. Limongelli, V. Lindahl, E. Lindorff-Larsen, K. Loverde, S. Lundborg, M. Luo, Y.L. Luque, F.J. Lynch, C.I. MacKerell, A. Magistrato, A. Marrink, S.J. Martin, H. McCammon, J.A. Merz, K. Moliner, V. Mulholland, A. Murad, S. Naganathan, A.N. Nangia, S. Noe, F. Noy, A. Oláh, J. O'Mara, M. Ondrechen, M.J. Onuchic, J.N. Onufriev, A. Osuna, S. Palermo, G. Panchenko, A.R. Pantano, S. Parish, C. Parrinello, M. Perez, A. Perez-Acle, T. Perilla, J.R. Pettitt, B.M. Pietropaolo, A. Piquemal, J.-P. Poma, A. Praprotnik, M. Ramos, M.J. Ren, P. Reuter, N. Roitberg, A. Rosta, E. Rovira, C. Roux, B. Röthlisberger, U. Sanbonmatsu, K. Schlick, T. Shaytan, A.K. Simmerling, C. Smith, J.C. Sugita, Y. Świderek, K. Taiji, M. Tao, P. Tikhonova, I.G. Tirado-Rives, J. Tuñón, I. Van Der Kamp, M.W. Van der Spoel, D. Velankar, S. Voth, G.A. Wade, R. Warshel, A. Welborn, V.V. Wetmore, S. Wong, C.F. Yang, L.-W. Zacharias, M. Orozco, M. Department of Molecular Biology University of California San DiegoCA United States Department of Cell and Molecular Biology Uppsala University Uppsala Sweden Laufer Center for Physical and Quantitative Biology Renaissance School of Medicine Stony Brook University Stony BrookNY United States Department of Biochemistry and Cell Biology Renaissance School of Medicine Stony Brook University Stony BrookNY United States Barcelona Spain European Molecular Biology Laboratory European Bioinformatics Institute Hinxton United Kingdom Structural Bioinformatics and Computational Biochemistry Department of Biochemistry University of Oxford Oxford United Kingdom Institut Pasteur Université Paris Cité CNRS UMR 3528 Computational Structural Biology Unit Paris France Department of Biochemistry and Biophysics University of Pennsylvania PhiladelphiaPA United States Division of Pharmacy and Optometry University of Manchester Manchester United Kingdom Scuola Internazionale Superiore di Studi Avanzati-SISSA Trieste Italy Computational Biomedicine Institute of Advanced Simulations IAS-5 Institute for Neuroscience and Medicine INM-9 Forschungszentrum Jülich GmbH Jülich Germany Department of Physics and Universitätsklinikum RWTH Aachen University Aachen Germany Department of Chemistry & Chemical Biology Rutgers University PiscatawayNJ United States Istituto Italiano di Tecnologia Drug Discovery and Development Bologna Italy Lausanne Switzerland Department of Chemistry University of California RiversideCA United States Department of Medicinal Chemistry College of Pharmacy University of Utah Salt Lake CityUT United States Department of Physics University of Washington SeattleWA United States Pacific Northwest National Laboratory RichlandWA United States LIA CNRS-UIUC UMR n°7019 Université de Lorraine Vandœuvre-lès-Nancy France Department of Physics University of Illinois at Urbana-Champaign UrbanaIL United States Department of Biochemistry and Molecular Biol

The communities that embraced data archiving efforts decades ago are now, in the era of data-driven biology, those gaining the most from the AI revolution. The structural biology community was a pioneer in this regard by establishing the Protein data Bank (PDB) in 1971 and making data accessible using the FAIR (Findable, Accessible, Interoperable and Reusable) principles even before these were articulated [1, 2]. The genomics/bioinformatics community has followed the example, establishing many widely used databases [3, 4]. By contrast, molecular simulation has been anchored in usage paradigms dating back to the seventies, when molecular dynamics (MD) simulation was first applied to study biomacromolecules [5]. At that time, MD was used by theoretical physicists and chemists in "proof of concept" simulations. Still, fifty years later, MD has evolved into a cornerstone molecular biology technique that can provide accurate quantitative analysis and property prediction. MD is now employed by tens of thousands of researchers worldwide, accounting for roughly 15% of global supercomputer usage. Unfortunately, these rich and costly data are not systematically maintained, and when further analyses are required, simulations have to be rerun-an unacceptable situation from scientific, environmental and sustainability standpoints. In this letter, we argue for a collaborative endeavor to archive MD simulation data and describe ongoing efforts to establish cost-effective and sustainable data archiving strategies. © 2024, CC BY-NC-SA.

关键词： Biotic

来源：评论

学校读者我要写书评

暂无评论

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

请选择保存的检索档案：

请选择收藏分类：

通借通还

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：