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Human genome meeting 2016 : Houston, TX, USA. 28 February - 2 March 2016

Human genomics 2016年第1期10 Suppl 1卷 12页

作者： A. K. Srivastava Y. Wang R. Huang C. Skinner T. Thompson L. Pollard T. Wood F. Luo R. Stevenson R. Polimanti J. Gelernter X. Lin I. Y. Lim Y. Wu A. L. Teh L. Chen I. M. Aris S. E. Soh M. T. Tint J. L. MacIsaac F. Yap K. Kwek S. M. Saw M. S. Kobor M. J. Meaney K. M. Godfrey Y. S. Chong J. D. Holbrook Y. S. Lee P. D. Gluckman N. Karnani A. Kapoor D. Lee A. Chakravarti C. Maercker F. Graf M. Boutros G. Stamoulis F. Santoni P. Makrythanasis A. Letourneau M. Guipponi N. Panousis M. Garieri P. Ribaux E. Falconnet C. Borel S. E. Antonarakis S. Kumar J. Curran J. Blangero S. Chatterjee J. Akiyama D. Auer C. Berrios L. Pennacchio T. R. Donti G. Cappuccio M. Miller P. Atwal A. Kennedy A. Cardon C. Bacino L. Emrick J. Hertecant F. Baumer B. Porter M. Bainbridge P. Bonnen B. Graham R. Sutton Q. Sun S. Elsea Z. Hu P. Wang Y. Zhu J. Zhao M. Xiong David A. Bennett A. Hidalgo-Miranda S. Romero-Cordoba S. Rodriguez-Cuevas R. Rebollar-Vega E. Tagliabue M. Iorio E. D’Ippolito S. Baroni B. Kaczkowski Y. Tanaka H. Kawaji A. Sandelin R. Andersson M. Itoh T. Lassmann Y. Hayashizaki P. Carninci A. R. R. Forrest C. A. Semple E. A. Rosenthal B. Shirts L. Amendola C. Gallego M. Horike-Pyne A. Burt P. Robertson P. Beyers C. Nefcy D. Veenstra F. Hisama R. Bennett M. Dorschner D. Nickerson J. Smith K. Patterson D. Crosslin R. Nassir N. Zubair T. Harrison U. Peters G. Jarvik F. Menghi K. Inaki X. Woo P. Kumar K. Grzeda A. Malhotra H. Kim D. Ucar P. Shreckengast K. Karuturi J. Keck J. Chuang E. T. Liu B. Ji A. Tyler G. Ananda G. Carter H. Nikbakht M. Montagne M. Zeinieh A. Harutyunyan M. Mcconechy N. Jabado P. Lavigne J. Majewski J. B. Goldstein M. Overman G. Varadhachary R. Shroff R. Wolff M. Javle A. Futreal D. Fogelman L. Bravo W. Fajardo H. Gomez C. Castaneda C. Rolfo J. A. Pinto K. C. Akdemir L. Chin S. Patterson C. Statz S. Mockus S. N. Nikolaev X. I. Bonilla L. Parmentier B. King F. Bezrukov G. Kaya V. Zoete V. Seplyarskiy H. Sharpe T. McKee K. Popadin N. Basset-Seguin R. Ben Chaabene M. Andrianova C. Verdan K. Grosdemange O. Sumara M. E JCSRI Greenwood Genetic Center Greenwood USA School of Computing Clemson University Clemson USA Biochemical Genetics Laboratory Greenwood Genetic Center Greenwood USA Department Psychiatry Yale Sch Med and VA CT Healthcare Center West Haven USA Department Genetics Yale Sch Med and VA CT Healthcare Center West Haven USA Department Neurobiology Yale Sch Med and VA CT Healthcare Center West Haven USA Singapore Institute for Clinical Sciences Singapore Singapore National University of Singapore Singapore Singapore University of British Columbia Vancouver Canada KK Women’s and Children’s Hospital Singapore Singapore University of Southampton and University Hospital Southampton NHS Foundation Trust Southampton UK University of Auckland Auckland New Zealand McKusick-Nathans Institute of Genetic Medicine Johns Hopkins University School of Medicine Baltimore USA Esslingen University of Applied Sciences Esslingen Germany German Cancer Research Center Heidelberg Germany Department of Genetic Medicine and Development University of Geneva Medical School Geneva Switzerland Geneva University Hospitals-HUG Service of Genetic Medicine Geneva Switzerland GE3 Institute of Genetics and Genomics of Geneva University of Geneva Medical School Geneva Switzerland South Texas Diabetes and Obesity Institute School of Medicine University of Texas Rio-Grande Valley Edinburg USA South Texas Diabetes and Obesity Institute School of Medicine University of Texas Rio-Grande Valley Brownsville USA Institute of Genetic Medicine Johns Hopkins University Baltimore USA Genomics Division Lawrence Berkeley National Laboratory Berkeley USA Molecular and Human Genetics Baylor College of Medicine Houston USA Department of Translational Medical Sciences Federico II University Naples Italy Metabolon Inc Durham USA Section of Pediatric Neurology and Neuroscience Baylor College of Medicine Houston USA Tawam Hospital Abu Dhabi United Arab Emirates Stanford Medical School Stanford USA Sch

O1 The metabolomics approach to autism: identification of biomarkers for early detection of autism spectrum disorder A. K. Srivastava, Y. Wang, R. Huang, C. Skinner, T. Thompson, L. Pollard, T. Wood, F. Luo, R. Stevenson O2 Phenome-wide association study for smoking- and drinking-associated genes in 26,394 American women with African, Asian, European, and Hispanic descents R. Polimanti, J. Gelernter O3 Effects of prenatal environment, genotype and DNA methylation on birth weight and subsequent postnatal outcomes: findings from GUSTO, an Asian birth cohort X. Lin, I. Y. Lim, Y. Wu, A. L. Teh, L. Chen, I. M. Aris, S. E. Soh, M. T. Tint, J. L. MacIsaac, F. Yap, K. Kwek, S. M. Saw, M. S. Kobor, M. J. Meaney, K. M. Godfrey, Y. S. Chong, J. D. Holbrook, Y. S. Lee, P. D. Gluckman, N. Karnani, GUSTO study group O4 High-throughput identification of specific qt interval modulating enhancers at the SCN5A locus A. Kapoor, D. Lee, A. Chakravarti O5 Identification of extracellular matrix components inducing cancer cell migration in the supernatant of cultivated mesenchymal stem cells C. Maercker, F. Graf, M. Boutros O6 Single cell allele specific expression (ASE) IN T21 and common trisomies: a novel approach to understand DOWN syndrome and other aneuploidies G. Stamoulis, F. Santoni, P. Makrythanasis, A. Letourneau, M. Guipponi, N. Panousis, M. Garieri, P. Ribaux, E. Falconnet, C. Borel, S. E. Antonarakis O7 Role of microRNA in LCL to IPSC reprogramming S. Kumar, J. Curran, J. Blangero O8 Multiple enhancer variants disrupt gene regulatory network in Hirschsprung disease S. Chatterjee, A. Kapoor, J. Akiyama, D. Auer, C. Berrios, L. Pennacchio, A. Chakravarti O9 Metabolomic profiling for the diagnosis of neurometabolic disorders T. R. Donti, G. Cappuccio, M. Miller, P. Atwal, A. Kennedy, A. Cardon, C. Bacino, L. Emrick, J. Hertecant, F. Baumer, B. Porter, M. Bainbridge, P. Bonnen, B. Graham, R. Sutton, Q. Sun, S. Elsea O10 A novel causal methylation network approach to Alzheimer’s

关键词： Pulmonary Arterial Hypertension Oral Squamous Cell Carcinoma Deep Neural Network Autosomal Recessive Polycystic Kidney Disease Whole Genome Bisulfite Sequencing

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Adaptive rate transmission for spectrum sharing system with quantized channel state information

Adaptive rate transmission for spectrum sharing system with ...

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Annual Conference on Information Sciences and Systems

作者： Abdallah, Mohamed Salem, Ahmed Alouini, Mohamed-Slim Qaraqe, Khalid A. Electrical and Computer Engineering Texas A and M University at Qatar PO Box 23874 Doha Qatar Department of Electronics and Electrical Communication Cairo University Giza Egypt Electrical Engineering Program KAUST Thuwal Saudi Arabia

ISBN: (纸本)9781424498475

The capacity of a secondary link in spectrum sharing systems has been recently investigated in fading environments. In particular, the secondary transmitter is allowed to adapt its power and rate to maximize its capacity subject to the constraint of maximum interference level allowed at the primary receiver. In most of the literature, it was assumed that estimates of the channel state information (CSI) of the secondary link and the interference level are made available at the secondary transmitter via an infinite-resolution feedback links between the secondary/primary receivers and the secondary transmitter. However, the assumption of having infinite resolution feedback links is not always practical as it requires an excessive amount of bandwidth. In this paper we develop a framework for optimizing the performance of the secondary link in terms of the average spectral efficiency assuming quantized CSI available at the secondary transmitter. We develop a computationally efficient algorithm for optimally quantizing the CSI and finding the optimal power and rate employed at the cognitive transmitter for each quantized CSI level so as to maximize the average spectral efficiency. Our results give the number of bits required to represent the CSI sufficient to achieve almost the maximum average spectral efficiency attained using full knowledge of the CSI for Rayleigh fading channels. © 2011 IEEE.

关键词： Channel state information

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Organic Thin Film Transistor architecture, parameters and their applications

Organic Thin Film Transistor architecture, parameters and th...

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International Conference on communication Systems and Network Technologies

作者： Mittal, Poornima Kumar, Brijesh Negi, Y.S. Kaushik, B.K. Singh, R.K. Electronics and Communication Engineering Graphic Era University-Dehradun Dehradun India Polymer Science and Technology Program DPT Indian Institute of Technology-Roorkee Roorkee India Department of Electronics and Computer Engineering Indian Institute of Technology-Roorkee Roorkee India Electronics and Communication Engineering Uttarakhand Technical University-Dehradun Dehradun India

ISBN: (纸本)9780769544373

Organic Thin Film Transistors (OTFTs) are promising devices for future development of variety of low-cost and large-area electronics applications such as flexible displays. This paper analyzes the performance of OTFT made of several organic semiconducting and insulating materials and further discusses their applications. Analysis of previous research work demonstrates that the mobility in OTFT decreases when the product of semiconducting film thickness and gate capacitance per unit area increases. The decrease is specified by a power law function with parameters for several organic semiconductors. OTFT characteristics have undergone spectacular improvements during the last few years. This paper explores the effect of variation of channel length from 40 nm to 20 nm on drain current for pentacene bottom contact structure. Variations in these quantities maps to variations in the electrical behaviour of devices. It has been found that drain current increases due to decrease in length of organic thin film conducting channel. It reviews recent progress in parameter properties for device designs and applications related to OTFTs. The performance of OTFTs is evaluated in terms of mobility, on/off current ratio, threshold voltage and sub threshold slope. This paper thoroughly discusses the overall performance and applications of OTFTs in various fields. © 2011 IEEE.

关键词： Drain current

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Adaptive rate transmission for spectrum sharing system with quantized channel state information

Adaptive rate transmission for spectrum sharing system with ...

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Annual Conference on Information Sciences and Systems (CISS)

作者： Mohamed Abdallah Ahmed Salem Mohamed-Slim Alouini Khalid A. Qaraqe Electrical and Computer Engineering Texas A and M University Qatar Doha Qatar Department of Electronics and Electrical Communication Cairo University Cairo Egypt Electrical Engineering Program KAUST Thuwal Saudi Arabia

关键词： Interference channels Transmitters Receivers Fading Signal to noise ratio Interference constraints

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Mapping the domain of engineering education research: Network approaches to bibliometric data collection and analysis

Mapping the domain of engineering education research: Networ...

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作者： Strobel, Johannes Radcliffe, David F. Rajan, Prashant Nawaz, Sadia Luo, Yi Choi, Jea H. INSPIRE Institute for P-12 Engineering Research and Learning Department of Engineering Education and Educational Technology Purdue University United States Department of Engineering Education School of Engineering Education Purdue University West Lafayette United States Department of Communication Purdue University West Lafayette United States School of Electrical and Computer Engineering Purdue University West Lafayette United States Learning Design and Technology Program Purdue University United States

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FIPACT: A Frame-Oriented Dynamic Bandwidth Allocation Scheme for Triple-Play Services over EPONs

FIPACT: A Frame-Oriented Dynamic Bandwidth Allocation Scheme...

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International Conference on computer communications and Networks (ICCCN)

作者： Hui-Tang Lin Chia-Lin Lai Wang-Rong Chang Chin-Lien Liu National Cheng Kung University Tainan TW Institute of Computer and Communication Engineering National Cheng Kung University Taiwan ICT-Enabled Healthcare Program Industrial Technology and Research Institute Taiwan

Ethernet Passive Optical Networks (EPONs) are not only cost-effective, but also provide high throughput, high bandwidth utilization, and low transmission latency. As a result, EPONs are a viable solution for overcoming the bandwidth bottleneck problem in local access networks. This study develops a novel Dynamic Bandwidth Allocation (DBA) scheme, designated as Frame-oriented Interleaved Polling with Adaptive Cycle Time (FIPACT), to provide a differentiated Quality-of-Service (QoS) capability in EPONs. FIPACT adopts a framed approach, in which the upstream network bandwidth is partitioned into successive frames. Within each frame, each Optical Network Unit (ONU) is guaranteed the network resources necessary to transmit a specific quota of Voice over Internet Protocol (VoIP), video, and Internet access traffic, respectively. Since FIPACT permits these three types of traffic stream to share the available bandwidth efficiently whilst still satisfying their respective QoS requirements, it provides an effective means of achieving differentiated triple-play services in EPONs. The simulation results demonstrate the effectiveness and efficiency of the proposed approach.

关键词： Streaming media Optical network units Bandwidth EPON IEEE 802.3 Standards Quality of service Protocols

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Uniform scanning model for cognitive communications

Uniform scanning model for cognitive communications

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作者： Liao, Chien-Hsing Woo, Tai-Kuo Yang, Wan-Shing Degree Program of Infornation Technology Fooyin University Taiwan Department of Information Management National Defense Management College Taiwan Department of Computer and Communication Engineering De-Lin Institute of Technology Taiwan

In this paper, in order to capture the spectrum holes with temporal, spatial and frequency variations in sophisticated FHSS radio environments and avoid interference to the existing primary users, a cognitive radio unit (CRU) model with a uniform scanning (U-scanning) technique and cognitive probability ratio (CPR) metric for cognitive communications has been proposed. In this model, real-time spectrum sensing characteristics are coordinated together with system parameters in temporal and frequency domains, e.g., scanning rate and framing processing time, for evaluating the performance of the cognitive radio communications under an elliptic operation scenario. The CPR value is inverse to the hopping rate, and a high CPR value means high spectrum awareness but low coexistence. Moreover, many intriguing numerical results are also illustrated to examine their interrelationships.

关键词： Cognitive radio

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Selection decode-and-forward relay networks with rectangular QAM in Nakagami-m fading channels

Selection decode-and-forward relay networks with rectangular...

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IEEE Wireless communications and Networking Conference 2010, WCNC 2010

作者： Al-Qahtani, Fawaz S. Duong, Trung Q. Gurung, Arun K. Bao, Vo Nguyen Quoc National Satellite Technology Program Saudi Arabia Radio Communication Group Blekinge Institute of Technology Sweden School of Electrical and Computer Engineering RMIT University Melbourne VIC Australia Department of Electrical Engineering University of Ulsan Korea Republic of

ISBN: (纸本)9781424463985

In this paper, we investigate the average symbol error probability (SEP) of fixed decode-and-forward relay networks over independent but not identically distributed Nakagami-m fading channels. We have derived closed form expression of SEP for general rectangular quadrature amplitude modulation (QAM) under relay selection scheme where only the best relay forwards message from the source to the destination. The expressions are in terms of hypergeometric series which can be efficiently numerically evaluated. The numerical results are validated with Monte-Carlo simulations. ©2010 IEEE.

关键词： Quadrature amplitude modulation

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Experimental measurement of growth patterns on fossil corals:Secular variation in ancient Earth-Sun distances

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Chinese Science Bulletin 2010年第35期55卷 4010-4017页

作者： ZHANG WeiJia1,3,4,LI ZhengBin2,3 & LEI Yang1 1 Department of Physics,Peking University,Beijing 100871,China 2 Department of Electrical engineering and computer Science,Peking University,Beijing 100871,China 3 State Key Laboratory of Advanced Optical communication Systems & Networks,Peking University,Beijing 100871,China 4 Committee of Yuanpei Honors program,Peking University,Beijing 100871,China Department of Physics Peking University Beijing 100871 China State Key Laboratory of Advanced Optical Communication Systems & Networks Peking University Beijing 100871 China Committee of Yuanpei Honors Program Peking University Beijing 100871 China Department of Electrical Engineering and Computer Science Peking University Beijing 100871 China

In recent years,much attention has been given to the increase in the Earth-Sun distance,with the modern rate reported as 5-15 m/cy on the basis of astronomical ***,traditional methods cannot measure the ancient leaving rates,so a myriad of research attempting to provide explanations were met with unmatched *** this paper we consider that the growth patterns on fossils could reflect the ancient Earth-Sun *** mechanical analysis of both the Earth-Sun and Earth-Moon systems,these patterns confirmed an increase in the Earth-Sun *** a large number of well-preserved specimens and new technology available,both the modern and ancient leaving rates could be measured with high precision,and it was found that the Earth has been leaving the Sun over the past 0.53 billion *** Earth's semi-major axis was 146 million kilometers at the beginning of the Phanerozoic Eon,equating to 97.6% of its current *** modern leaving rates are 5-14 m/cy,whereas the ancient rates were much *** results indicate a special expansion with an average expansion coefficient of 0.57H0 and deceleration in the form of Hubble *** the basis of experimental results,the Earth's semi-major axis could be represented by a simple formula that matches fossil measurements.

关键词：地球太阳古代距离生长模式实验石珊瑚量化

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An efficient ICA approach based on neural network framework for biomedical applications

An efficient ICA approach based on neural network framework ...

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2010 6th IEEE World Congress on Computational Intelligence, WCCI 2010 - 2010 International Joint Conference on Neural Networks, IJCNN 2010

作者： Lin, Yue-Der Hsu, Chih-Yu Chen, Hung-Yun Tseng, Kuo-Kun Department of Automatic Control Engineering Master Program of Biomedical Informatics and Biomedical Engineering Feng Chia University Taichung Taiwan Department of Information and Communication Engineering Chaoyang University of Technology Wufeng Taichung County Taiwan Department of Automatic Control Engineering Feng Chia University Taichung Taiwan Department of Computer Science and Engineering HungKuang University Taichung Taiwan

ISBN: (纸本)9781424469178

The paper developed a block-wise approach for ICA algorithms which can improve the computational efficiency of ICA without the degradation of performance for the separation of biomedical signals. Source signals including electrocardiogram (ECG), electromyogram (EMG) and 60-Hz sinusoid are linearly mixed for experimental tests. The mean-square errors (MSE) between the original sources and the separated signals are calculated for the evaluation of separation performance. These results demonstrated that the proposed block-wise approach can achieve the desired separation performance of signals in a more efficient way. © 2010 IEEE.

关键词： Independent component analysis

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