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Single and Mitochondrial Gene Inheritance Disorder Prediction Using Machine Learning

Computers, Materials & Continua 2022年第10期73卷 953-963页

作者： Muhammad Umar Nasir Muhammad Adnan Khan Muhammad Zubair Taher MGhazal Raed A.Said Hussam Al Hamadi Riphah School of Computing&Innovation Faculty of ComputingRiphah International University Lahore CampusLahore54000Pakistan Pattern Recognition and Machine Learning Lab Department of SoftwareGachon UniversitySeongnam13120GyeonggidoKorea Faculty of Computing Riphah International UniversityIslamabad45000Pakistan School of Information Technology Skyline University CollegeSharjah1797UAE Network and Communication Technology Lab Center for Cyber SecurityFaculty of Information Science and Technology Universiti Kebangsaan Malaysia43600Malaysia Canadian University Dubai00000UAE Cyber-Physical Systems Khalifa UniversityAbu Dhabi127788UAE

One of the most difficult jobs in the post-genomic age is identifying a genetic disease from a massive amount of genetic ***,the complicated genetic disease has a very diverse genotype,making it challenging to find genetic *** is a challenging process since it must be completed effectively and *** research article focuses largely on which patients are more likely to have a genetic disorder based on numerous medical *** the patient’s medical history,we used a genetic disease prediction algorithm that predicts if the patient is likely to be diagnosed with a genetic *** predict and categorize the patient with a genetic disease,we utilize several deep and machine learning techniques such as Artificial neural network(ANN),K-nearest neighbors(KNN),and Support vector machine(SVM).To enhance the accuracy of predicting the genetic disease in any patient,a highly efficient approach was utilized to control how the model can be *** predict genetic disease,deep and machine learning approaches are *** most productive tool model provides more precise *** simulation results demonstrate that by using the proposed model with the ANN,we achieve the highest model performance of 85.7%,84.9%,84.3%accuracy of training,testing and validation *** approach will undoubtedly transform genetic disorder prediction and give a real competitive strategy to save patients’lives.

关键词： Genetic disorder machine learning deep learning single gene inheritance gene disorder mitochondrial gene inheritance disorder

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CurvDrop: A Ricci Curvature Based Approach to Prevent Graph Neural Networks from Over-Smoothing and Over-Squashing 23

CurvDrop: A Ricci Curvature Based Approach to Prevent Graph ...

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2023 World Wide Web Conference, WWW 2023

作者： Liu, Yang Zhou, Chuan Pan, Shirui Wu, Jia Li, Zhao Chen, Hongyang Zhang, Peng Academy of Mathematics and Systems Science Chinese Academy of Sciences China Amss Chinese Academy of Science School of Cyber Security University of Chinese Academy of Science China School of Information and Communication Technology Griffith University Australia School of Computing Macquarie University Australia Hangzhou link2do Technology China Research Center for Graph Computing Zhejiang Lab China Cyberspace Institute of Advanced Technology Guangzhou University China

ISBN: (纸本)9781450394161

Graph neural networks (GNNs) are powerful models to handle graph data and can achieve state-of-the-art in many critical tasks including node classification and link prediction. However, existing graph neural networks still face both challenges of over-smoothing and over-squashing based on previous literature. To this end, we propose a new Curvature-based topology-aware Dropout sampling technique named CurvDrop, in which we integrate the Discrete Ricci Curvature into graph neural networks to enable more expressive graph models. Also, this work can improve graph neural networks by quantifying connections in graphs and using structural information such as community structures in graphs. As a result, our method can tackle the both challenges of over-smoothing and over-squashing with theoretical justification. Also, numerous experiments on public datasets show the effectiveness and robustness of our proposed method. The code and data are released in https://***/liu-yang-maker/Curvature-based-Dropout. © 2023 ACM.

关键词： Graph neural networks

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Uncertainty-Aware Trajectory Prediction via Rule-Regularized Heteroscedastic Deep Classification

arXiv

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arXiv 2025年

作者： Manas, Kumar Schlauch, Christian Paschke, Adrian Wirth, Christian Klein, Nadja Department of Mathematics and Computer Science Freie Universität Berlin Germany Continental Automotive Technologies GmbH AI Lab Berlin Germany Karlsruhe Institute of Technology Scientific Computing Center Germany Fraunhofer Institute for Open Communication Systems Berlin Germany

Deep learning-based trajectory prediction models have demonstrated promising capabilities in capturing complex interactions. However, their out-of-distribution generalization remains a significant challenge, particularly due to unbalanced data and a lack of enough data and diversity to ensure robustness and calibration. To address this, we propose SHIFT (Spectral Heteroscedastic Informed Forecasting for Trajectories), a novel framework that uniquely combines well-calibrated uncertainty modeling with informative priors derived through automated rule extraction. SHIFT reformulates trajectory prediction as a classification task and employs heteroscedastic spectral-normalized Gaussian processes to effectively disentangle epistemic and aleatoric uncertainties. We learn informative priors from training labels, which are automatically generated from natural language driving rules, such as stop rules and drivability constraints, using a retrieval-augmented generation framework powered by a large language model. Extensive evaluations over the nuScenes dataset, including challenging low-data and cross-location scenarios, demonstrate that SHIFT outperforms state-of-the-art methods, achieving substantial gains in uncertainty calibration and displacement metrics. In particular, our model excels in complex scenarios, such as intersections, where uncertainty is inherently higher. Project page: https://***/SHIFT/. © 2025, CC BY.

关键词： Deep learning

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Aligning Recommendation and Conversation via Dual Imitation

Aligning Recommendation and Conversation via Dual Imitation

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2022 Conference on Empirical Methods in Natural Language Processing, EMNLP 2022

作者： Zhou, Jinfeng Wang, Bo Huang, Minlie Zhao, Dongming Huang, Kun He, Ruifang Hou, Yuexian College of Intelligence and Computing Tianjin University Tianjin China State Key Laboratory of Communication Content Cognition People's Daily Online Beijing China The CoAI Group DCST Institute for Artificial Intelligence State Key Lab of Intelligent Technology and Systems China Beijing National Research Center for Information Science and Technology Tsinghua University Beijing100084 China AI Lab China Mobile Communication Group Tianjin Co. Ltd. China

Human conversations of recommendation naturally involve the shift of interests which can align the recommendation actions and conversation process to make accurate recommendations with rich explanations. However, existing conversational recommendation systems (CRS) ignore the advantage of user interest shift in connecting recommendation and conversation, which leads to an ineffective loose coupling structure of CRS. To address this issue, by modeling the recommendation actions as recommendation paths in a knowledge graph (KG), we propose DICR (Dual Imitation for Conversational Recommendation), which designs a dual imitation to explicitly align the recommendation paths and user interest shift paths in a recommendation module and a conversation module, respectively. By exchanging alignment signals, DICR achieves bidirectional promotion between recommendation and conversation modules and generates high-quality responses with accurate recommendations and coherent explanations. Experiments demonstrate that DICR outperforms the state-of-the-art models on recommendation and conversation performance with automatic, human, and novel explainability metrics. © 2022 Association for Computational Linguistics.

关键词： Knowledge graph

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Condition Monitoring and Maintenance Management with Grid-Connected Renewable Energy systems

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Computers, Materials & Continua 2022年第8期72卷 3999-4017页

作者： Md.Mottahir Alam Ahteshamul Haque Mohammed Ali Khan Nebras M.Sobahi Ibrahim Mustafa Mehedi Asif Irshad Khan Department of Electrical and Computer Engineering(ECE) King Abdulaziz UniversityJeddah 21589Saudi Arabia Advance Power Electronics Research Lab Department of Electrical EngineeringJamia Millia IslamiaNew Delhi 110025India Department of Electrical Power Engineering Faculty of Electrical Engineering and CommunicationBrno University of TechnologyBrno 61600Czech Republic Center of Excellence in Intelligent Engineering Systems(CEIES) King Abdulaziz UniversityJeddah 21589Saudi Arabia Computer Science Department Faculty of Computing and Information TechnologyKing Abdulaziz UniversityJeddah 21589Saudi Arabia

The shift towards the renewable energy market for carbon-neutral power generation has encouraged different governments to come up with a plan of *** with the endorsement of renewable energy for harsh environmental conditions like sand dust and snow,monitoring and maintenance are a few of the prime *** problems were addressed widely in the literature,but most of the research has drawbacks due to long detection time,and high misclassification *** to overcome these drawbacks,and to develop an accurate monitoring approach,this paper is motivated toward the understanding of primary failure concerning a grid-connected photovoltaic(PV)system and highlighted along with a brief overview on existing fault detection *** on the drawback a data-driven machine learning approach has been used for the identification of fault and indicating the maintenance unit regarding the operation and maintenance ***,the system was tested with a 4 kWp grid-connected PV system,and a decision tree-based algorithm was developed for the identification of a *** results identified 94.7%training accuracy and 14000 observations/sec prediction speed for the trained classifier and improved the reliability of fault detection nature of the grid-connected PV operation.

关键词： Fault detection machine learning fault ride through

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An LMI-based Composite Nonlinear Controller Design for Robust Stabilization of a Knee Rehabilitation Exoskeleton Robot

An LMI-based Composite Nonlinear Controller Design for Robus...

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International Conference on Control, Decision and Information Technologies (CoDIT)

作者： Sahar Jenhani Hassène Gritli Jyotindra Narayan Laboratory of Robotics Informatics and Complex Systems (RISC Lab - LR16ES07) National Engineering School of Tunis University of Tunis El Manar Tunis Tunisia Higher Institute of Information and Communication Technologies University of Carthage Tunis Tunisia RISC Lab Department of Computing Imperial College London UK Chair of Digital Health Universität Bayreuth Germany

ISBN: (数字)9798350373974

ISBN: (纸本)9798350373981

This paper introduces a novel robust control strategy specifically designed for a one-degree-of-freedom (1-DoF) knee rehabilitation exoskeleton robot, focusing on position control. Our approach addresses several key challenges, including state constraints, parameter uncertainties, solid and viscous frictions, and external disturbances. We suggest a composite controller that combines a nonlinear controller with a linear state feedback controller in order to successfully address these issues. By utilizing a quadratic Lyapunov function, we derive the expression of the nonlinear control law and establish the Linear Matrix Inequality (LMI) conditions for computing the matrix gain of the linear controller, ensuring robust stabilization of the exoskeleton robot to the desired position. These conditions are derived through the application of advanced mathematical techniques such as the matrix inversion lemma, the Young inequality, the Schur complement, and the S-procedure lemma. Numerical results show the effectiveness of our suggested control law, demonstrating the continuous convergence of the intended angular position to the real one, even when external disturbances and uncertainties are present. Overall, our research not only presents a novel methodology for robust control but also delivers promising results that underscore the efficacy of our approach in achieving stable and reliable performance for 1-DoF knee exoskeleton robots.

关键词： Robust control Uncertain systems State feedback Uncertainty Exoskeletons Position control Solids Linear matrix inequalities Reliability Robots

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A flexible capacitive photoreceptor for the biomimetic retina

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Light(Science & Applications) 2022年第1期11卷 38-49页

作者： Mani Teja Vijjapu Mohammed E.Fouda Agamyrat Agambayev Chun Hong Kang Chun-Ho Lin Boon S.Ooi Jr-Hau He Ahmed M.Eltawil Khaled N.Salama Sensors lab Advanced Membranes and Porous Materials CenterComputerElectrical and Mathematical Science and Engineering DivisionKing Abdullah University of Science and Technology(KAUST)Thuwal 23955-6900Kingdom of Saudi Arabia Communication and Computing Systems Lab ComputerElectrical and Mathematical Science and Engineering DivisionKing Abdullah University of Science and Technology(KAUST)Thuwal 23955-6900Kingdom of Saudi Arabia Department of Electrical Engineering and Computer Science University of California-IrvineIrvineCA 92612USA Department of Electrical Computer and Energy EngineeringArizona State UniversityTempeAZUSA Computer Electrical and Mathematical Science and Engineering DivisionKing Abdullah University of Science and Technology(KAUST)Thuwal 23955-6900Kingdom of Saudi Arabia Department of Materials Science and Engineering City University of Hong KongHong Kong SARChina

Neuromorphic vision sensors have been extremely beneficial in developing energy-efficient intelligent systems for robotics and privacy-preserving security *** is a dire need for devices to mimic the retina's photoreceptors that encode the light illumination into a sequence of spikes to develop such ***,we develop a hybrid perovskite-based flexible photoreceptor whose capacitance changes proportionally to the light intensity mimicking the retina's rod cells,paving the way for developing an efficient artificial retina *** proposed device constitutes a hybrid nanocomposite of perovskites(methyl-ammonium lead bromide)and the ferroelectric terpolymer(polyvinylidene fluoride trifluoroethylene-chlorofluoroethylene).A metal-insulator-metal type capacitor with the prepared composite exhibits the unique and photosensitive capacitive behavior at various light intensities in the visible light *** proposed photoreceptor mimics the spectral sensitivity curve of human photopic *** hybrid nanocomposite is stable in ambient air for 129 weeks,with no observable degradation of the composite due to the encapsulation of hybrid perovskites in the hydrophobic *** functionality of the proposed photoreceptor to recognize handwritten digits(MNIST)dataset using an unsupervised trained spiking neural network with 72.05%recognition accuracy is *** demonstration proves the potential of the proposed sensor for neuromorphic vision applications.

关键词： perovskite illumination preserving

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Robust Stabilization of a Knee Exoskeleton Robot Using an LMI-Based Composite Controller

Robust Stabilization of a Knee Exoskeleton Robot Using an LM...

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Indian Control Conference (ICC)

作者： Sahar Jenhani Hassène Gritli Jyotindra Narayan Laboratory of Robotics Informatics and Complex Systems (RISC Lab - LR16ES07) National Engineering School of Tunis University of Tunis El Manar Tunis Tunisia RISC Lab. Higher Institute of Information and Communication Technologies University of Carthage Borj Cedria Tunis Tunisia Department of Mechanical Engineering Thapar Institute of Engineering and Technology Patiala Punjab India Department of Computing Imperial College London UK

ISBN: (数字)9798331517212

ISBN: (纸本)9798331517229

Rehabilitation exoskeleton robots are vital for restoring lower limb functionality in individuals with locomotor disorders. Extensive research has focused on optimizing the control of these robotic systems and make them more stable. However, there is still a considerable gap in developing robust controllers. This work introduces a robust control approach tailored for a one-degree-of-freedom (1-DoF) knee rehabilitation exoskeleton robot. Emphasizing position control, our method addresses challenges such as parameter uncertainties, solid and viscous frictions, external disturbances, and motion constraints. To effectively manage these issues, we propose a composite controller that integrates a linear state-feedback controller and a nonlinear control law. By employing a quadratic Lyapunov function, we derive the expression of the nonlinear controller and establish the LMI conditions required for calculating the matrix gain of the composite controller using two different design methods. To confirm the developed LMI conditions and demonstrate the proposed control method's ability to ensure robust position control of the knee exoskeleton robotic system, simulation results are finally provided.

关键词： Robust control Uncertain systems Limbs Friction Exoskeletons Position control Solids systems simulation Robots Lyapunov methods

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Leveraging Machine Learning for Gait Phase Classification with Varied Training Methods

Leveraging Machine Learning for Gait Phase Classification wi...

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International Conference on Advanced Technologies for Signal and Image Processing (ATSIP)

作者： Amal Mekni Jyotindra Narayan Hassène Gritli Higher Institute of Information and Communication Technologies University of Carthage RISC Laboratory (LR16ES07) Borj Cedria Tunis Tunisia Department of Computing Imperial College London UK Chair of Digital Health Universität Bayreuth Germany Laboratory of Robotics Informatics and Complex Systems (RISC Lab - LR16ES07) National Engineering School of Tunis University of Tunis El Manar Le Belvédère Tunis Tunisia

ISBN: (数字)9798350351484

ISBN: (纸本)9798350351491

Accurate gait phase recognition is crucial for real-time analysis and intervention in rehabilitation, biomechanics, and prosthetics. However, achieving this is challenging due to the diverse machine learning (ML) training methods. This study employs ML algorithms to classify gait phases, focusing on stance and swing phases, utilizing open-source data from $\mathbf{1 0 0}$ participants ($41.91 \pm 5.3$ yrs). The classification algorithms considered are k-Nearest Neighbor (k-NN), Logistic Regression (LR), Decision Tree (DT), Random Forest (RF), Support Vector Machine (SVM), and Naive Bayesian (NB) algorithms. The study evaluates these algorithm performances using two training methods with five and ten lower body movements: one randomly selects $80 \%$ of stance and swing phase data for training, while the other divides data by participants, allocating $80 \%$ for training and $20 \%$ for testing. When assessing accuracy with five movements, RF achieved $99.8 \%$ for both training methods. With ten movements, RF achieved a high accuracy of $99.9 \%$ using the second method. Notably, the performance of all ML algorithms exhibited improvement when considering data from ten movements versus five. Additionally, it was observed that the second training method proved more effective with five-movement data compared to data involving ten movements. This comprehensive evaluation highlights the potential of machine learning algorithms for accurate gait phase recognition in diverse applications with varied training methods.

关键词： Training Radio frequency Support vector machines Machine learning algorithms Accuracy Real-time systems Classification algorithms

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Optimized efficient attention-based network for facial expressions analysis in neurological health care

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Computers in Biology and Medicine 2024年 179卷 108822-108822页

作者： Munsif, Muhammad Sajjad, Muhammad Ullah, Mohib Tarekegn, Adane Nega Cheikh, Faouzi Alaya Tsakanikas, Panagiotis Muhammad, Khan Sejong University Seoul143-747 Korea Republic of Digital Image Processing Lab Department of Computer Science Islamia College Peshawar25000 Pakistan Department of Computer Science Norwegian University for Science and Technology Gjøvik2815 Norway Department of Computer Science Norwegian University for Science and Technology Gjøvik2815 Norway Institute of Communication and Computer Systems National Technical University of Athens Athens15773 Greece Department of Applied Artificial Intelligence School of Convergence College of Computing and Informatics Sungkyunkwan University Seoul03063 Korea Republic of

Facial Expression Analysis (FEA) plays a vital role in diagnosing and treating early-stage neurological disorders (NDs) like Alzheimer's and Parkinson's. Manual FEA is hindered by expertise, time, and training requirements, while automatic methods confront difficulties with real patient data unavailability, high computations, and irrelevant feature extraction. To address these challenges, this paper proposes a novel approach: an efficient, lightweight convolutional block attention module (CBAM) based deep learning network (DLN) to aid doctors in diagnosing ND patients. The method comprises two stages: data collection of real ND patients, and pre-processing, involving face detection and an attention-enhanced DLN for feature extraction and refinement. Extensive experiments with validation on real patient data showcase compelling performance, achieving an accuracy of up to 73.2%. Despite its efficacy, the proposed model is lightweight, occupying only 3MB, making it suitable for deployment on resource-constrained mobile healthcare devices. Moreover, the method exhibits significant advancements over existing FEA approaches, holding tremendous promise in effectively diagnosing and treating ND patients. By accurately recognizing emotions and extracting relevant features, this approach empowers medical professionals in early ND detection and management, overcoming the challenges of manual analysis and heavy models. In conclusion, this research presents a significant leap in FEA, promising to enhance ND diagnosis and *** code and data used in this work are available at: https://***/munsif200/Neurological-Health-Care. © 2024 Elsevier Ltd

关键词： Feature extraction

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