检索结果-内蒙古大学图书馆

arXiv 2020年

作者： Trobia, José Gabrick, Enrique C. Seifert, Evandro G. Borges, Fernando S. Protachevicz, Paulo R. Szezech, José D. Iarosz, Kelly C. Santos, Moises S. Caldas, Iberê L. Tian, Kun Ren, Hai-Peng Grebogi, Celso Batista, Antonio M. Graduate Program in Science - Physics State University of Ponta Grossa Ponta GrossaPR84030-900 Brazil Department of Mathematics and Statistics State University of Ponta Grossa Ponta GrossaPR84030-900 Brazil Department of Physics State University of Ponta Grossa Ponta GrossaPR84030-900 Brazil Center for Mathematics Computation and Cognition Federal University of ABC São Bernardo do CampoSP09606-045 Brazil Institute of Physics University of São Paulo São PauloSP05508-900 Brazil Faculty of Telêmaco Borba FATEB Telêmaco BorbaPR84266-010 Brazil Graduate Program in Chemical Engineering Federal Technological University of Paraná Ponta Grossa Paraná84016-210 Brazil Shaanxi Key Lab of Complex System Control and Intelligent Information Processing Xi’an University of Technology Xi’an710048 China Xi’an Technological University Xi’an710021 China Institute for Complex Systems and Mathematical Biology University of Aberdeen AberdeenAB24 3UE United Kingdom

Cancer is a term used to refer to a large set of diseases. The cancerous cells grow and divide and, as a result, they form tumours that grow in size. The immune system recognise the cancerous cells and attack them, though, it can be weakened by the cancer. One type of cancer treatment is chemotherapy, which uses drugs to kill cancer cells. Clinical, experimental, and theoretical research has been developed to understand the dynamics of cancerous cells with chemotherapy treatment, as well as the interaction between tumour growth and immune system. We study a mathematical model that describes the cancer growth, immune system response, and chemotherapeutic agents. The immune system is composed of resting cells that are converted to hunting cells to combat the cancer. In this work, we consider drug sensitive and resistant cancer cells. We show that the tumour growth can be controlled not only by means of different chemotherapy protocols, but also by the immune system that attacks both sensitive and resistant cancer cells. Furthermore, for all considered protocols, we demonstrate that the time delay from resting to hunting cells plays a crucial role in the combat against cancer cells. Copyright © 2020, The Authors. All rights reserved.

关键词： Chemotherapy

来源：评论

学校读者我要写书评

暂无评论

Mathematical model of brain tumour growth with drug resistance

arXiv

引用

arXiv 2020年

作者： Trobia, José Tian, Kun Batista, Antonio M. Grebogi, Celso Ren, Hai-Peng Santos, Moises S. Protachevicz, Paulo R. Borges, Fernando S. Szezech, José D. Viana, Ricardo L. Caldas, Iberê L. Iarosz, Kelly C. Department of Mathematics and Statistics State University of Ponta Grossa Ponta GrossaPR84030-900 Brazil Graduate in Science Program - Physics State University of Ponta Grossa Ponta GrossaPR84030-900 Brazil Shaanxi Key Lab of Complex System Control and Intelligent Information Processing Xi’an University of Technology Xi’anPR710048 China Institute of Physics University of São Paulo São PauloSP05508-900 Brazil Institute for Complex Systems and Mathematical Biology University of Aberdeen AberdeenAB24 3UE United Kingdom Xi’an Technological University Xi’anPR710021 China Center for Mathematics Computation and Cognition Federal University of ABC São Bernardo do CampoSP09606-045 Brazil Department of Physics Federal University of Paraná CuritibaPR80060-000 Brazil Faculdade de Telêmaco Borba FATEB Telêmaco BorbaPR84266-010 Brazil

Brain tumours are masses of abnormal cells that can grow in an uncontrolled way in the brain. There are different types of malignant brain tumours. Gliomas are malignant brain tumours that grow from glial cells and are identified as astrocytoma, oligodendroglioma, and ependymoma. We study a mathematical model that describes glia-neuron interaction, glioma, and chemotherapeutic agent. In this work, we consider drug sensitive and resistant glioma cells. We show that continuous and pulsed chemotherapy can kill glioma cells with a minimal loss of neurons. © 2020, CC BY.

关键词： Tumors

来源：评论

学校读者我要写书评

暂无评论

Spike-burst chimera states in an adaptive exponential integrate-and-fire neuronal network

arXiv

引用

arXiv 2019年

作者： Santos, Moises S. Protachevicz, Paulo R. Iarosz, Kelly C. Caldas, Iberê L. Viana, Ricardo L. Borges, Fernando S. Ren, Hai-Peng Szezech, José D. Batista, Antonio M. Grebogi, Celso Department of Physics Federal University of Paraná CuritibaPR80060-000 Brazil Graduate in Science Program - Physics State University of Ponta Grossa Ponta Grossa PR84030-900 Brazil Institute of Physics University of São Paulo São PauloSP05508-900 Brazil Center for Mathematics Computation and Cognition Federal University of ABC São Bernardo do CampoSP09606-045 Brazil Shaanxi Key Laboratory of Complex System Control and Intelligent Information Processing Xian University of Technology Xi'an710048 China Xian Technological University Xi'an710021 China Graduate in Science Program - Physics State University of Ponta Grossa Ponta Grossa PR84030-900 Brazil Institute for Complex Systems and Mathematical Biology King's College University of Aberdeen AberdeenAB24 3UE United Kingdom

Chimera states are spatiotemporal patterns in which coherence and incoherence coexist. We observe the coexistence of synchronous (coherent) and desynchronous (incoherent) domains in a neuronal network. The network is composed of coupled adaptive exponential integrate-and-fire neurons that are connected by means of chemical synapses. In our neuronal network, the chimera states exhibit spatial structures both with spikes and bursts activities. Furthermore, those desynchronised domains not only have either spike or burst activity, but we show that the structures switch between spikes and bursts as the time evolves. Moreover, we verify the existence of multicluster chimera states. Copyright © 2019, The Authors. All rights reserved.

关键词： Neural networks

来源：评论

学校读者我要写书评

暂无评论

Improving liver fibrosis diagnosis based on forward and backward second harmonic generation signals

引用

Applied Physics Letters 2015年第8期106卷

作者： Peng, Qiwen Zhuo, Shuangmu So, Peter T. C. Yu, Hanry Biosystems and Micromechanics IRG Singapore-MIT Alliance for Research and Technology 1 CREATE Way #04-13/14 Enterprise Wing Singapore138602 Singapore Institute of Laser and Optoelectronics Technology Fujian Normal University Fuzhou350007 China Computation and System Biology Program Singapore-MIT Alliance 4 Engineering Drive 3 E4-04-10 117576 Singapore Institute of Bioengineering and Nanotechnology A STAR The Nanos 31 Biopolis Way #04-01 Singapore138669 Singapore Department of Mechanical Engineering Massachusetts Institute of Technology CambridgeMA02139 United States Department of Biological Engineering Massachusetts Institute of Technology CambridgeMA02139 United States Department of Physiology Yong Loo Lin School of Medicine National University of Singapore Singapore117597 Singapore Mechanobiology Institute National University of Singapore Singapore117411 Singapore

The correlation of forward second harmonic generation (SHG) signal and backward SHG signal in different liver fibrosis stages was investigated. We found that three features, including the collagen percentage for forward SHG, the collagen percentage for backward SHG, and the average intensity ratio of two kinds of SHG signals, can quantitatively stage liver fibrosis in thioacetamide-induced rat model. We demonstrated that the combination of all three features by using a support vector machine classification algorithm can provide a more accurate prediction than each feature alone in fibrosis diagnosis. © 2015 AIP Publishing LLC.

关键词： Harmonic generation

来源：评论

学校读者我要写书评

暂无评论

26th Annual computational Neuroscience Meeting (CNS*2017): Part 3 Antwerp, Belgium. 15-20 July 2017 Abstracts

引用

BMC NEUROSCIENCE 2017年第SUPPL 1期18卷 95-176页

作者： [Anonymous] Department of Neuroscience Yale University New Haven CT 06520 USA Department Physiology & Pharmacology SUNY Downstate Brooklyn NY 11203 USA NYU School of Engineering 6 MetroTech Center Brooklyn NY 11201 USA Departament de Matemàtica Aplicada Universitat Politècnica de Catalunya Barcelona 08028 Spain Institut de Neurobiologie de la Méditerrannée (INMED) INSERM UMR901 Aix-Marseille Univ Marseille France Center of Neural Science New York University New York NY USA Aix-Marseille Univ INSERM INS Inst Neurosci Syst Marseille France Laboratoire de Physique Théorique et Modélisation CNRS UMR 8089 Université de Cergy-Pontoise 95300 Cergy-Pontoise Cedex France Department of Mathematics and Computer Science ENSAT Abdelmalek Essaadi’s University Tangier Morocco Laboratory of Natural Computation Department of Information and Electrical Engineering and Applied Mathematics University of Salerno 84084 Fisciano SA Italy Department of Medicine University of Salerno 84083 Lancusi SA Italy Dipartimento di Fisica Università degli Studi Aldo Moro Bari and INFN Sezione Di Bari Italy Data Analysis Department Ghent University Ghent Belgium Coma Science Group University of Liège Liège Belgium Cruces Hospital and Ikerbasque Research Center Bilbao Spain BIOtech Department of Industrial Engineering University of Trento and IRCS-PAT FBK 38010 Trento Italy Department of Data Analysis Ghent University Ghent 9000 Belgium The Wellcome Trust Centre for Neuroimaging University College London London WC1N 3BG UK Department of Electronic Engineering NED University of Engineering and Technology Karachi Pakistan Blue Brain Project École Polytechnique Fédérale de Lausanne Lausanne Switzerland Departement of Mathematics Swansea University Swansea Wales UK Laboratory for Topology and Neuroscience at the Brain Mind Institute École polytechnique fédérale de Lausanne Lausanne Switzerland Institute of Mathematics University of Aberdeen Aberdeen Scotland UK Department of Integrativ

来源：评论

学校读者我要写书评

暂无评论

25th Annual computational Neuroscience Meeting CNS-2016, Seogwipo City, South Korea, July 2-7, 2016 Abstracts

引用

BMC NEUROSCIENCE 2016年第1期17卷 1-112页

作者： [Anonymous] Computational Neurobiology Laboratory The Salk Institute for Biological Studies San Diego USA UNIC CNRS Gif sur Yvette France The European Institute for Theoretical Neuroscience (EITN) Paris France ATR Computational Neuroscience Laboratories Kyoto Japan Krembil Research Institute University Health Network Toronto Canada Department of Physiology University of Toronto Toronto Canada Department of Medicine (Neurology) University of Toronto Toronto Canada Department of Physics University of New Hampshire Durham USA Department of Neurophysiology Nencki Institute of Experimental Biology Warsaw Poland Department of Theory Wigner Research Centre for Physics of the Hungarian Academy of Sciences Budapest Hungary Department of Mathematical Sciences KAIST Daejoen Republic of Korea Department of Mathematics University of Houston Houston USA Department of Biochemistry & Cell Biology and Institute of Biosciences and Bioengineering Rice University Houston USA Department of Biology and Biochemistry University of Houston Houston USA Grupo de Neurocomputación Biológica Dpto. de Ingeniería Informática Escuela Politécnica Superior Universidad Autónoma de Madrid Madrid Spain Department of Biological Sciences University of Southern California Los Angeles USA Center for Neuroscience Korea Institute of Science and Technology Seoul South Korea Department of Neurology Albert Einstein College of Medicine Bronx USA Center for Neuroscience KIST Seoul South Korea Department of Neuroscience University of Science and Technology Daejon South Korea Systems Neuroscience Group QIMR Berghofer Medical Research Institute Herston Australia Department of Psychology Yonsei University Seoul South Korea Department of Psychiatry Kyung Hee University Hospital at Gangdong Seoul South Korea Department of Psychiatry Veterans Administration Boston Healthcare System and Harvard Medical School Brockton USA Department of Electrical and Electronic Engineering The University of Melbourne Parkvil

A1 Functional advantages of cell-type heterogeneity in neural circuits Tatyana O. Sharpee A2 Mesoscopic modeling of propagating waves in visual cortex Alain Destexhe A3 Dynamics and biomarkers of mental disorders Mitsuo Kawato F1 Precise recruitment of spiking output at theta frequencies requires dendritic h-channels in multi-compartment models of oriens-lacunosum/moleculare hippocampal interneurons Vladislav Sekulić, Frances K. Skinner F2 Kernel methods in reconstruction of current sources from extracellular potentials for single cells and the whole brains Daniel K. Wójcik, Chaitanya Chintaluri, Dorottya Cserpán, Zoltán Somogyvári F3 The synchronized periods depend on intracellular transcriptional repression mechanisms in circadian clocks. Jae Kyoung Kim, Zachary P. Kilpatrick, Matthew R. Bennett, Kresimir Josić O1 Assessing irregularity and coordination of spiking-bursting rhythms in central pattern generators Irene Elices, David Arroyo, Rafael Levi, Francisco B. Rodriguez, Pablo Varona O2 Regulation of top-down processing by cortically-projecting parvalbumin positive neurons in basal forebrain Eunjin Hwang, Bowon Kim, Hio-Been Han, Tae Kim, James T. McKenna, Ritchie E. Brown, Robert W. McCarley, Jee Hyun Choi O3 Modeling auditory stream segregation, build-up and bistability James Rankin, Pamela Osborn Popp, John Rinzel O4 Strong competition between tonotopic neural ensembles explains pitch-related dynamics of auditory cortex evoked fields Alejandro Tabas, André Rupp, Emili Balaguer-Ballester O5 A simple model of retinal response to multi-electrode stimulation Matias I. Maturana, David B. Grayden, Shaun L. Cloherty, Tatiana Kameneva, Michael R. Ibbotson, Hamish Meffin O6 Noise correlations in V4 area correlate with behavioral performance in visual discrimination task Veronika Koren, Timm Lochmann, Valentin Dragoi, Klaus Obermayer O7 Input-location dependent gain modulation in cerebellar nucleus neurons Maria Psarrou, Maria Schilstra, Neil Davey, Benjamin Torben-Ni

关键词：

来源：评论

学校读者我要写书评

暂无评论

Automated Scoring of Liver Fibrosis through Combined Features from Different Collagen Groups

Automated Scoring of Liver Fibrosis through Combined Feature...

引用

Annual International Conference of the IEEE Engineering in Medicine and biology Society

作者： Shuoyu Xu Dean Tai Aileen Wee Roy Welsch Peter So Hanry Yu Jagath Rajapakse Computation and System Biology Program Histoindex Pte.Ltd. Department of Pathology Yong Loo Lin School of Medicine National University of Singapore National University Hospital Sloan School of Management Massachusetts Institute of Technology Mechanical Engineering and Biological Engineering Massachusetts Institute of Technology Physiology Yong Loo Lin School of Medicine National University of Singapore Director of Bioinformatics Research Center School of Computer Engineering Nanyang Technological University

ISBN: (纸本)9781424441211

Liver biopsy remains the gold standard in monitoring progression of liver fibrosis associated with an abnormal increase in collagen. Descriptive scoring systems are still being widely used to grade biopsy samples. In this study, we propose a new set of features by clustering collagen fibers into three groups first based on their localization and connectivity properties, and then by extracting morphological features of collagen fibers. The new feature set is compared to the earlier features used in classification of liver fibrosis, which were based on the total amount of collagen fibers. Our results show that new features lead to more accurate grading of liver fibrosis.

关键词： Liver Fibrosis collagen fiber Scoring Scoring liver biopsy Collagen gold standard

来源：评论

学校读者我要写书评

暂无评论

Windows computer laboratory as a tutorial for undergraduate electromagnetics

引用

Computer Applications in Engineering Education 1995年第3期3卷 183-183页

作者： McCulloch, J. Keddy, W.A. Stuchly, M.A. University of Victoria Department of Electrical and Computer Engineering University of Victoria Victoria British Columbia Canada Janet McCulloch:is a native of Toronto Canada where she briefly attended both York University and the University of Toronto before she set off on a year-long adventure through the Middle East and North Africa. When she returned to Canada she relocated to California. She spent a number of years living both in Los Angeles and coastal Northern California interspersed with several extended trips through the United States Mexico and Central America. Ms. McCulloch moved to Victoria British Columbia in 1989 and a year later registered in the cooperative education program in Electrical Engineering at the University of Victoria. She is presently in the fifth and final year of the program and has her sights set on graduate school. Besides the work described in this article she has been very much involved in the use of technology to assist in the delivery of curriculum at the senior secondary level. She lives on a country property a half-hour from the University with her husband her horse and three cats. W. Alfred Keddy:is an applications programmer/analyst for the Department of Electrical and Computer Engineering at the University of Victoria. He received a BEng (1988) in Electrical Engineering and an MASc (1994) from the University of Victoria. His research interests include distributed systems image processing local area networks VLSI and DSP system design for computation and communication and human–computer interface design. Maria A. Stuchly:received an MSc in Electrical Engineering in 1962 from Warsaw Technical University and a PhD in Electrical Engineering from the Polish Academy of Sciences in 1970. Between the years of 1962 and 1970 she was with the Warsaw Technical University an Institute of the Polish Academy of Sciences. After immigrating to Canada during 1970 her first position was with the University of Manitoba. In 1976 she became employed by the Bureau of Radi

Contents and implementation of a computer laboratory for undergraduate electromagnetics are described. The laboratory consists of four 3-hour sessions covering vector calculus, Maxwell's equations (integral and differential forms), wave propagation in materials, and wave behavior at planar interfaces. Each session contains theory (in the Help file), animations (where relevant) and a quiz. The program runs on IBM compatible 486-based PCs in a Windows environment and uses the Borland C ++ 4.0 compiler.

关键词：

来源：评论

学校读者我要写书评

暂无评论

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

请选择保存的检索档案：

请选择收藏分类：

通借通还

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：