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Annual International Conference of the IEEE engineering in Medicine and Biology Society

作者： Ali Shahidi Zandi Guy A. Dumont Manouchehr Javidan Reza Tafreshi Department of Electrical & Computer Engineering at The University of British Columbia MD FRCPC Division of Neurology Department of Medicine at The University of British Columbia Mechanical Engineering Program at Texas A&M University at Qatar

ISBN: (纸本)9781424441211

We propose a novel patient-specific method for predicting epileptic seizures by analysis of positive zero-crossing intervals in scalp electroencephalogram (EEG). In real-time analysis, the histogram of these intervals for the current EEG epoch is computed, and the values which correspond to the bins discriminating between interictal and preictal references are selected as an observation. Then, the set of observations from the last 5 min is compared with two reference sets of data points (interictal and preictal) using a variational Gaussian mixture model (GMM) of the data, and a combined index is computed. Comparing this index with a patient-specific threshold, an alarm sequence is produced for each channel. Finally, a seizure prediction alarm is generated according to channel-based information. The proposed method was evaluated using ～40.3 h of scalp EEG recordings from 6 patients with total of 28 partial seizures. A high sensitivity of 95% was achieved with a false prediction rate of 0.134/h and an average prediction time of 22.8 min for the test dataset.

关键词： epileptic seizure Gauss Scalp EEG Dataset Alarm Bins Electroencephalography

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SYSTEMS BIOLOGY IN BARLEY POWDERY MILDEW INTERACTIONS

SYSTEMS BIOLOGY IN BARLEY POWDERY MILDEW INTERACTIONS

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The 13th International Cereal Rusts and Powdery Mildews Conference(第13届国际禾谷类锈病与白粉病大会)

作者： Roger WISE Priyanka SURANA Greg FUERST Ruo XU Dan NETTLETON Divya MISTRY Julie DICKERSON Lin WANG Tom BRUTNELL Department of Plant Pathology and Microbiology Center for Plant Responses to Environmental StressesIowa State UniversityAmesIowa 50011USA Department of Statistics Iowa State UniversityAmesIowa 50011USA Bioinformatics and Computational Biology Graduate ProgramIowa State UniversityAmesIowa 50011USA Bioinformatics and Computational Biology Graduate ProgramIowa State UniversityAmesIowa 50011USA Bioinformatics and Computational Biology Graduate Program Iowa State UniversityAmesIowa 50011USA Department of Plant Pathology and MicrobiologyCenter for Plant Responses to Environmental StressesIowa State UniversityAmesIowa 50011USA Crop and Insect Genetics Genomicsand Informatics Research UnitU.S.Department of Agriculture-Agricultural Research ServiceIowa State UniversityAmesIowa 50011USA Department of Plant Pathology and Microbiology Center for Plant Responses to Environmental StressesIowa State UniversityAmesIowa 50011USA Department of StatisticsIowa State UniversityAmesIowa 50011USA Bioinformatics and Computational Biology Graduate ProgramIowa State UniversityAmesIowa 50011USA Bioinformatics and Computational Biology Graduate Program Iowa State UniversityAmesIowa 50011USA Crop and Insect GeneticsGenomicsand Informatics Research UnitU.S.Department of Agriculture-Agricultural Research ServiceIowa State UniversityAmesIowa 50011USA Department of Electrical and Computer Engineering Iowa State UniversityAmesIowa 50011USA Boyce Thompson Institute for Plant ResearchCornell UniversityIthacaNY

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Frame coherence and sparse signal processing

Frame coherence and sparse signal processing

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IEEE International Symposium on Information Theory

作者： Dustin G. Mixon Waheed U. Bajwa Robert Calderbank Program in Applied and Computational Mathematics Princeton University Princeton NJ USA Department of Electrical and Computer Engineering Duke University Durham NC USA

The sparse signal processing literature often uses random sensing matrices to obtain performance guarantees. Unfortunately, in the real world, sensing matrices do not always come from random processes. It is therefore desirable to evaluate whether an arbitrary matrix, or frame, is suitable for sensing sparse signals. To this end, the present paper investigates two parameters that measure the coherence of a frame: worst-case and average coherence. We first provide several examples of frames that have small spectral norm, worst-case coherence, and average coherence. Next, we present a new lower bound on worst-case coherence and compare it to the Welch bound. Later, we propose an algorithm that decreases the average coherence of a frame without changing its spectral norm or worst-case coherence. Finally, we use worst-case and average coherence, as opposed to the Restricted Isometry Property, to garner near-optimal probabilistic guarantees on both sparse signal detection and reconstruction in the presence of noise. This contrasts with recent results that only guarantee noiseless signal recovery from arbitrary frames, and which further assume independence across the nonzero entries of the signal-in a sense, requiring small average coherence replaces the need for such an assumption.

关键词： Coherence Signal processing algorithms Noise Harmonic analysis Noise measurement Geometry

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Stabilization of hydroxyl-terminated silanes in porous silicon for in-situ DNA synthesis

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Physica Status Solidi (C) Current Topics in Solid State Physics 2011年第6期8卷 1851-1855页

作者： Lawrie, Jenifer L. Weiss, Sharon M. Interdisciplinary Graduate Program in Materials Science Vanderbilt University Nashville TN United States Department of Electrical Engineering and Computer Science Vanderbilt University Nashville TN United States

Passivation of porous silicon sensors is a critical issue for achieving high sensitivity and selectivity toward biomolecule targets that may be detected in complex physiologic solution. Without appropriate passivation, degradation of the porous silicon matrix inhibits the repeatability of optical measurements and limits applications in complex media. In this work, we present a method for stabilizing TEOS-HBA monolayers in porous silicon. Annealing of the silane at 200°C for 16 hours, followed by a deionized water wash for a minimum of one hour, results in a porous silicon surface that is highly stable in a number of solvents. Annealing improves cross-linking of surface-attached silane molecules for added stability, and hydrolyzing facilitates removal of weakly bound multilayers. This surface treatment procedure is of considerable interest in applications such as DNA synthesis where hydroxyl functionality is critical and a thick silane surface coating is not desired. © 2011 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

关键词： Passivation

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Prediction of spatiotemporal patterns of neural activity using a higher-order Markov representation of instantaneous pairwise maximum entropy model

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BMC Neuroscience 2011年第1期12卷 1-2页

作者： Mehdi Aghagolzadeh Karim Oweiss Department of Electrical and Computer Engineering Michigan State University East Lansing MI 48823 USA Neuroscience Program Michigan State University East Lansing MI 48823 USA

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BioN∅T: A searchable database of biomedical negated sentences

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BMC Bioinformatics 2011年第1期12卷 1-7页

作者： Agarwal, Shashank Yu, Hong Kohane, Issac Medical Informatics College of Engineering and Applied Sciences University of Wisconsin-Milwaukee 3200 N. Cramer St. Milwaukee WI 53201-0784 United States Department of Computer Science and Electrical Engineering College of Engineering and Applied Sciences University of Wisconsin-Milwaukee 3200 N. Cramer St. Milwaukee WI 53201-0784 United States Department of Health Sciences College of Health Science University of Wisconsin-Milwaukee 2400 E. Hartford Ave. Milwaukee WI 53211 United States Children's Hospital Informatics Program Children's Hospital 300 Longwood Ave. Enders-6 Boston MA 02115 United States

Background: Negated biomedical events are often ignored by text-mining applications;however, such events carry scientific significance. We report on the development of BioN∅T, a database of negated sentences that can be used to extract such negated ***: Currently BioN∅T incorporates ≈32 million negated sentences, extracted from over 336 million biomedical sentences from three resources: ≈2 million full-text biomedical articles in Elsevier and the PubMed Central, as well as ≈20 million abstracts in PubMed. We evaluated BioN∅T on three important genetic disorders: autism, Alzheimer's disease and Parkinson's disease, and found that BioN∅T is able to capture negated events that may be ignored by ***: The BioN∅T database can be a useful resource for biomedical researchers. BioN∅T is freely available at http://***/. In future work, we will develop semantic web related technologies to enrich BioN∅T. © 2011 Agarwal et al;licensee BioMed Central Ltd.

关键词： Database systems

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Application of STATCOM to improve the high-voltage-ride-through capability of wind turbine generator

Application of STATCOM to improve the high-voltage-ride-thro...

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IEEE Innovative Smart Grid Technologies - Asia (ISGT Asia)

作者： Y. M. Alharbi A. M. Shiddiq Yunus A. Abu-Siada King Abdullah scholarship program Australia Department of Mechanical Engineering Energy Conversion Study State Polytechnic of Ujungpandang Makassar Indonesia Department of Electrical and Computer Engineering Curtin University of Technology Perth WA Australia

Variable speed wind turbine with full scale converter or so-called type-D wind turbine generator worldwide installation has been significantly increased in the last few years. Voltage Swell in the grid side may cause the wind turbine to be disconnected from the grid. In this paper, STATCOM is applied to improve the high voltage ride through capability of type-D wind turbine during voltage swell in the grid side. Simulation is carried out using MATLAB/Simulink software. Results show that STATCOM can significantly improve the high voltage ride through (HVRT) capability of type-D wind turbine and prevents it from being disconnected from the grid during certain level of voltage swell in the grid side.

关键词： Automatic voltage control Wind turbines Educational institutions Reactive power Control systems Power system stability Wind energy

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Redundant information encoding in primary motor cortex during motor tasks

Redundant information encoding in primary motor cortex durin...

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International IEEE/EMBS Conference on Neural engineering, CNE

作者： Kelvin So Karunesh Ganguly Michael Gastpar Jose M. Carmena Department of Electrical Engineering and Computer Sciences University of California Berkeley CA USA Neurology and Rehabilitation Services San Francisco Veterans Affairs Medical Center San Francisco CA USA Department of Electrical Engineering and Computer Sciences and the Helen Wills Neuroscience Institute University of California Berkeley CA USA Department of Electrical Engineering and Computer Sciences the Program in Cognitive Science and the Helen WillsNeuroscience Institute University of California Berkeley CA USA

Information encoded in neuron ensembles has previously been hypothesized to be highly redundant, despite the apparent inefficiency of a redundant encoding system. The recent availability of intracortical, multi-electrode recordings has enabled the possibility of exploring how neuronal ensembles encode information as a whole. Applying concepts from information theory, we examined the redundancy of the target information encoded in both contralateral and ipsilateral hemispheres of the primary motor cortex (M1) in macaque monkeys performing a center-out reaching task. During movement, we reliably found neurons in contralateral M1 to contain higher target information and to be more redundant than ipsilateral M1 neurons, which is consistent with the conventional understanding that motor control is mainly governed by contralateral M1. Secondly, neuron ensembles in both hemispheres showed largely redundant information encoding. These results suggest that redundancy in information encoding is highly prevalent in the motor cortex and may contribute to proficient motor control.

关键词： Neurons Redundancy Encoding Neuroscience Muscles Firing Mutual information

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Megapixel digital PCR

Megapixel digital PCR

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15th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2011, MicroTAS 2011

作者： Heyries, Kevin A. Tropini, Carolina VanInsberghe, Michael Doolin, Callum Petriv, Oleh I. Singhal, Anupam Leung, Kaston Hugesman, Curtis B. Hansen, Carl L. Centre for High-Throughput Biology University of British Columbia Vancouver BC Canada Department of Physics and Astronomy University of British Columbia Vancouver BC Canada Department of Chemical and Biological Engineering University of British Columbia Vancouver BC Canada Department of Electrical and Computer Engineering University of British Columbia Vancouver BC Canada Michael Smith Laboratories University of British Columbia Vancouver BC Canada Biophysics Program Stanford University Stanford CA United States

ISBN: (纸本)9781618395955

We report a microfluidic 'megapixel' digital polymerase chain reaction (PCR) device that uses a surface tension-based sample partitioning approach along with integrated dehydration control to enable high-fidelity single DNA molecule amplification in 1,000,000 reactors of picoliter volume, in arrays with densities up to 440,000 reactors cm-2. This device achieves a dynamic range of 107, single-nucleotide-variant detection below one copy per 100,000 wild-type sequences, and the discrimination of a 1% difference in chromosome copy number. Copyright © (2011) by the Chemical and Biological Microsystems Society.

关键词： Genome

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Autonomous passive light tracking utilizing single-wall carbon nanotube enhanced opto-thermo-mechanical elastomer actuators

Autonomous passive light tracking utilizing single-wall carb...

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International Conference on Solid State Sensors and Actuators (TRANSDUCERS)

作者： Ye Liu Chensha Li Chi-Wei Lo Hongrui Jiang Electrical and Computer Engineering Department University of Wisconsin Madison Madison WI USA Materials Science Program University of Wisconsin Madison Madison WI USA

We have developed novel opto-thermo-mechanical actuators by effectively distributing a significant amount of single-wall carbon nanotube (SWCNT, up to 0.7%w/w) into liquid crystal elastomer (LCE) matrices. These SWCNT/LCE actuators exhibit a great potential to be utilized in MEMS applications, as they respond to a wide spectrum of visible/near-infrared light, and possess a large reversible compressive strain (up to 35%) when stimulated. Autonomous and passive light tracking is demonstrated here as one of the applications. With a simple design, the actuators are able to adaptively tilt a solar cell towards the light source by a degree of ~15° (with an incident light intensity of 1.6 kW/m 2 ). As a result, the photocurrent output of the solar cell is significantly enhanced (up to 247.10%) without any other control system or external energy source.

关键词： Actuators Photovoltaic cells Photoconductivity Films Carbon nanotubes Light sources Micromechanical devices

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