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Convex analysis for separation of functional patterns in DCE-MRI: A longitudinal study to antiangiogenic therapy

Convex analysis for separation of functional patterns in DCE...

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IEEE Workshop on Machine Learning for Signal Processing

作者： Tsung-Han Chan Li Chen Peter L. Choyke Chong-Yung Chi Yue Wang Department of Electrical and Computer Engineering Virginia Polytechnic Institute and State University Arlington VA USA Institute of Communications Engineering and Department of Electrical Engineering National Tsing Hua University Hsinchu Taiwan Molecular Imaging Program National Cancer Institute National Institutes of Health DHHS Bethesda MD USA

Dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) can characterize vascular heterogeneity, and has potential utility in assessment of the efficacy of angiogenesis inhibitors in cancer treatment. Due to the heterogeneous nature of tumor microvasculature, the measured signals can be represented as the mixture of the permeability images corresponding to different perfusion rates. We recently reported a hybrid convex analysis of mixture framework for unmixing of non-negative yet dependent angiogenic permeability distributions (APDs) and perfusion time activity curves (TACs). In our last work, we presented an underlying theory to infer the concept that the TACs can be identified by finding the lateral edges of an observation-constructed convex pyramid when the well-grounded points exist for all APDs. For fulfilling this concept, a hybrid method including non-negative clustered component analysis, convex analysis, and least-squares fitting with non-negativity constraints was developed. In this paper, we use computer simulations to validate the performance of our reported framework, and further apply it to three sets of real DCE-MRI data, before and during the treatment period, for assessing the response to antiangiogenic therapy. The experimental results are not only surprisingly meaningful in biology and clinic, but also capable of reflecting the efficacy of angiogenesis inhibitors in cancer treatment.

关键词： Pattern analysis Medical treatment Magnetic resonance imaging Permeability Cancer Pixel Image analysis Inhibitors Independent component analysis Source separation

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Novel Mems-based technology for measuring the mechanical properties of a live biological cell

Novel Mems-based technology for measuring the mechanical pro...

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11th International Congress and Exhibition on Experimental and Applied Mechanics 2008

作者： Gneriich, Markus Zhang, Wenyue Donahue, Henry Voloshin, Arkady Tatic-Lucic, Svetlana Sherman Fairchild Center Department of Electrical and Computer Engineering Lehigh University Bethlehem PA 18015 United States Pennsylvania State University College of Medicine Hershey PA United States Bioengineering Program Lehigh University Bethlehem PA 18015 United States Department of Mechanical Engineering and Mechanics Lehigh University 16A Memorial Drive East Bethlehem PA 18015 United States Lehigh University Bethlehem PA 10815 United States

ISBN: (纸本)9781605604152

This paper presents an experimental platform for measuring the mechanical properties of live biological cells. The polymer-based MEMS device integrates a V-shaped electrothermal actuator (ETA) array, a force sensor, a displacement sensor, a thermal sensor, and a cell-positioning system in a single chip. The integrated cell-positioning system based on dielectrophoresis precisely places a cell to a designed spot, the MEMS ETA array provides a predefined deformation to the cell, the force and displacement sensors measure the magnitude of the force applied to the cell and the corresponding cell deformation, and the thermal sensor monitors temperature in the liquid cell medium environment during the experiment. This MEMS device was able to compress a NIH3T3 fibroblast cell and cause 25% mechanical strain. © 2008 Society for Experimental Mechanics Inc.

关键词： Electrophoresis

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A comparison of molecular approaches for generating sparse and structured multiresolution representations of audio and music signals

A comparison of molecular approaches for generating sparse a...

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7th European Conference on Noise Control 2008, EURONOISE 2008

作者： Sturm, B. Shynk, J.J. McLeran, A. Roads, C. Daudet, L. University of California Department of Electrical and Computer Engineering Box 117 Santa Barbara CA 93106 United States University of California Media Arts and Technology Program Santa Barbara CA 93106 United States UPMC Univ Paris 06 LAM IJLRA 11 rue de Lourmel 75015 Paris France

We compare the characteristics and performance of joint (single-step) and sequential (two-step) approaches for creating sparse and structured acoustic signal representations derived using overcomplete methods (OMs). A joint approach, such as molecular matching pursuit (MMP), attempts to find coherent structures in a signal as part of the decomposition process, while a sequential approach, such as agglomerative clustering (AC), attempts to find coherent structures after the signal decomposition. We review each approach, and examine their performance using real audio and music signals.

关键词： Audio acoustics

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Benchmarking comparison of thermal and diode sensors for pulsed power measurement

Benchmarking comparison of thermal and diode sensors for pul...

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ARFTG Conference

作者： Sivalingam Somasundaram Meena Charles Baylis Lawrence Dunleavy Center for Wireless and Microwave Information Systems Department of Electrical Engineering University of South Florida Tampa FL USA Wireless and Microwave Circuits and Systems Program Department of Electrical and Computer Engineering Baylor University Waco TX USA Modelithics Inc. Tampa Florida USA

A pulsed power system has been constructed to explore conditions under which accurate pulsed power measurements can be made with both a thermal sensor and a diode sensor. For the thermal sensor, pulsed power is estimated from a simple calculation based on the average power of the pulsed RF signal. For the diode sensor, gating is used to enable direct measurement of the pulsed power. As expected, the results of measurements taken with varying pulse lengths and a constant period show that the dynamic range of the thermal sensor is approximately proportional to the pulse length. The results also indicate that, while a thermal sensor can provide accurate results for many situations, the diode sensor can be used to measure with higher precision than the thermal sensor for lower duty cycles. The paper demonstrates a benchmarking procedure that can be used to explore limitations and capabilities of power sensors as well as elements such as the input RF switch used for pulsed power measurements.

关键词： Diodes Thermal sensors Pulse measurements Power measurement Pulse power systems Sensor systems Switches Power system measurements Length measurement Dynamic range

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Nanoscale porous silicon waveguides for biosensing applications

Nanoscale porous silicon waveguides for biosensing applicati...

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21st Annual Meeting of the IEEE Lasers and Electro-Optics Society, LEOS 2008

作者： Rong, G. Wei, X. Kang, C. Liscidini, M. Sipe, J.E. Mernaugh, R.L. Weiss, S.M. Department of Electrical Engineering and Computer Science Vanderbilt University Nashville TN 37235 United States Interdisciplinary Graduate Program in Materials Science Vanderbilt University Nashville TN 37235 United States Department of Physics Institute for Optical Sciences University of Toronto Toronto ON M5S 1A7 Canada Department of Biochemistry Vanderbilt University Nashville TN 37235 United States

Nanoscale porous silicon waveguides, both on silicon substrates and free-standing membranes, are explored for biosensing applications. Measured detection limits in the nanomolar range are reported for DNA sensing. ... 详细信息

ISBN: (纸本)9781424419326

关键词： Porous silicon

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Sub-nanosecond infrared optical parametric pulse generation in PPLN pumped by a seeded fiber amplifier

Sub-nanosecond infrared optical parametric pulse generation ...

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Advanced Solid-State Photonics, ASSP 2008

作者： Cocuzzi, Matthew D. Schepler, Kenneth L. Powers, Peter E. Lima, Ivan T. Air Force Research Lab Wright Patterson Air Force Base 2241 Avionics Circle WPAFB OH 45433-7304 United States Department of Physics and the Electro-Optics Program University of Dayton 300 College Park Dayton OH 45469-2314 United States Department of Electrical and Computer Engineering North Dakota State University Fargo ND 58105 United States

Sub-nanosecond pulses generated in a microchip laser were amplified in an Yb-doped, polarization-maintaining fiber amplifier and converted with 24% efficiency to infrared wavelengths using a periodically poled lithium... 详细信息

ISBN: (纸本)1557528500

关键词： Fiber amplifiers

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The Third International Conference on human-robot interaction

The Third International Conference on human-robot interactio...

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作者： Fong, Terry Dautenhahn, Kerstin Scheutz, Matthias Demiris, Yiannis Intelligent Robotics Group NASA Ames Research Center Department of Artificial Intelligence School of Computer Science University of Herfordshire Herfordshire United Kingdom Adaptive Systems Research Group University of Herfordshire Herfordshire United Kingdom Department of Cognitive Science Computer Science and Informatics Cognitive Science Program Indiana University Bloomington IN United States Intelligent Robotics Team Department of Electrical Engineering Imperial College London London United Kingdom

The third international conference on Human-Robot Interaction (HRI-2008) was held in Amsterdam, The Netherlands, March 12-15, 2008. The theme of HRI-2008, "living with robots," highlights the importance of the technical and social issues underlying human-robot interaction with companion and assistive robots for long-term use in everyday life and work activities. More than 250 researchers, practitioners, and exhibitors attended the conference, and many more contributed to the conference as authors or reviewers. HRI-2009 will be held in San Diego, California, from March 11-13, 2009. Copyright © 2008, Association for the Advancement of Artificial Intelligence. All rights reserved.

关键词： Human robot interaction

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A New Anti-Collision Based on A-Priori Information

A New Anti-Collision Based on A-Priori Information

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5th International Conference on electrical engineering/Electronics, computer, Telecommunications and Information Technology (ECTI-CON 2008), vol.2

作者： Sarawut Makwimanloy Piya Kovintavewat Urachada Ketprom Charturong Tantibundhit Chaichana Mitrpant Electrical and Computer Engineering Department Thammasat University Thailand RFID Technology and Applications Research Unit Nakhon Pathom Rajabhat University Nakhon Pathom Thailand RFID Program National Electronics and Computer Technology Center Thailand

A collision occurs when more than two tags present in the reader's field of a radio frequency identification system. Anti-collision algorithms such as binary trees and dynamic framed slotted aloha (DFSA) have been employed to prevent such a collision. The identification number of tag consists of 64 bits and certain parts of 64 bits can be considered a priori-information. This paper proposes a new anti-collision algorithm based on a-priori information about the manufacturer code. This prior-information reduces the number of bits to analyze in the algorithm, hence reduces the operation time for the faster read-performance. Results indicate that the proposed anti-collision algorithm required a less number of used time slots, thus minimizing the operation time more than 50% comparing to the existing ones.

关键词： Radiofrequency identification Heuristic algorithms Binary trees ISO Approximation algorithms Algorithm design and analysis Partitioning algorithms

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Monolithic integration of a p-n junction and porous silicon host matrix for next generation photovoltaics

Monolithic integration of a p-n junction and porous silicon ...

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2008 33rd IEEE Photovoltaic Specialists Conference

作者： J.P. Clarkson G. See B. Veeramachaneni L.L. Gadeken K.D. Hirschman P.M. Fauchet BetaBatt Inc. Houston TX USA Microelectronic Engineering Department Rochester Institute of Technology Rochester NY USA Department of Electrical and Computer Engineering University of Rochester Rochester NY USA Materials Science Program University of Rochester Rochester NY USA

We report on a novel three-dimensional Si p-n junction that is capable of performing photovoltaic energy conversion. Vertically aligned pores with a very high aspect ratio of ≫ 100 were formed into a p-type Si substrate through an electrochemical etching process. A conformal p-n junction was then created in the etched porous silicon region by introducing phosphorous dopants through proximity rapid thermal diffusion. Al electrodes were subsequently evaporated on the front and back sides of the diode to establish electrical contact to the n-type and p-type regions respectively. Typical device structures resulted in highly three-dimensional diodes with pores extending up to 100 μm deep into the bulk Si. Porous films this thick correspond to an effective internal surface area of ∼ 5150 cm 2 /cm 3 . This ultimately makes the device applicable to both inorganic and organic next generation photovoltaics where it is desirable to maximize the amount of interfacing surface to a given photoactive compound. Dark box and illuminated I–V measurements of the device demonstrated successful monolithic integration of a p-n diode and a high internal surface area host matrix.

关键词： Monolithic integrated circuits P-n junctions Silicon Photovoltaic cells Diodes Etching Energy conversion Rapid thermal processing Electrodes Contacts

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An improved proof for RFID tags

An improved proof for RFID tags

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International Conference on electrical engineering/Electronics, computer, Telecommunications and Information Technology, ECTI-CON

作者： Thiti Nuamcherm Piya Kovintavewat Charturong Tantibundhit Urachada Ketprom Chaichana Mitrpant Electrical and Computer Engineering Department Thammasat University Thailand RFID Technology and Application Research Unit Nakhon Pathom Rajabhat University Nakhon Pathom Thailand RFID Program National Electronics and Computer Technology Center Thailand

An RFID system consists of an RFID reader, a server connected to a database, and RFID tags attached to the objects needed to be identified. We are interested in the case where two tags are needed to be simultaneously scanned in a readerpsilas field, for which many protocols have been proposed in literature. They however are all insecure for the special case, where an adversary, acting as a reader, can penetrate the server and access data stored in the server. In this paper, we propose a protocol to remedy this problem for two-tag environment. In addition, it can be extended to more-than-two-tag environment without much increasing total amount of time to scan all the tags.

关键词： Servers Protocols Radiofrequency identification Security Media Access Protocol Privacy Argon

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