Today, machine learning is used in a broad variety of applications. Convolution neural networks (CNN), in particular, are widely used to analyze visual data. The fashion industry is catching up to the growing usage of...
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Great efforts have been devoted in the past many years to synthesizing clinically important novel heterocyclic compounds using transition metal-mediated reactions. Further, transition metal-catalyzed cascade or tandem...
Great efforts have been devoted in the past many years to synthesizing clinically important novel heterocyclic compounds using transition metal-mediated reactions. Further, transition metal-catalyzed cascade or tandem reactions for the synthesis of crucial heterocyclic scaffolds have attracted a lot of attention in the last few years. These reactions can form multiple bonds in one pot without changing the reaction conditions and overall reduce the reaction steps and requirement of intermediate purifications. The reduction of reaction steps leads to saving reagents, energy and eliminates waste generation which makes the cascade reactions eco-friendly as well as highly economical. In this context, several transition metal catalysts like Rh, Pd, Cu, Ru, Ir, Fe, etc. have been employed to perform these kinds of reactions. In this view, carbenes or their precursors like diazo, hydrazones, etc. played an important role in making them more advantageous. On the other hand, computational chemistry is playing an important role and growing its roots in various fields of chemistry day by day. Particularly, in organic synthesis, DFT studies are widely used for mechanistic investigation and treated as an important tool for novel synthesis route detection. In the first chapter of this thesis, we are highlighting some appreciable efforts made in recent years towards the synthesis of highly important novel heterocyclic moieties by using palladium catalyzed cascade reactions including carbene transfer, isocyanide insertion, C-H activation, and cyclization as the vital steps. Also, mechanistic investigation via various experimental and computational studies, further transformation and applications, etc. are covered in these reports. In the second chapter, we have described a divergent and selective synthesis of (E)-3-alkylidene oxindole, which is a highly valuable framework due to its presence in the biologically important molecules, via palladium-catalyzed multicomponent reaction of
Consumer confidence is, in the present time, a dilemma given the steadily rising number of deceptive and inaccurate AI-generated reviews on internet marketplaces. There is an urgent need for a thorough dataset, which ...
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Vehicle anti-infiltration systems play a crucial role in modern security infrastructure, particularly in military security scenarios where unauthorized access poses a significant threat. However, current vehicle infil...
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In image registration, traditional optimization techniques are incapable of detecting the optimum value of geometric transformation parameters. To resolve this issue, a novel scheme of monomodal (isomodal) biomedical ...
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This study presents a comprehensive intervention approach designed to address dyscalculia in early education. The strategy employs a comprehensive approach that incorporates colour identification, numerical enumeratio...
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Since the past few decades, high vehicular growth rate along with vulnerable climatic conditions have been deteriorating the pavement performance during its service life. Deteriorations are in the form of rutting and ...
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In recent years,the growth of female employees in the commercial market and industries has *** a result,some people think travelling to distant and isolated locations during odd hours generates new threats to women’s...
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In recent years,the growth of female employees in the commercial market and industries has *** a result,some people think travelling to distant and isolated locations during odd hours generates new threats to women’s *** exponential increase in assaults and attacks on women,on the other hand,is posing a threat to women’s growth,development,and *** the time of the attack,it appears the women were immobilized and needed immediate *** self-defense isn’t sufficient against abuse;a new technological solution is desired and can be used as quickly as hitting a switch or *** proposed Women Safety Gadget(WSG)aims to design a wearable safety device model based on Internet-of-Things(IoT)and Cloud *** is designed in three layers,namely layer-1,having an android app;layer-2,with messaging and location tracking system;and layer-3,which updates information in the cloud *** can detect an unsafe condition by the pressure sensor of the finger on the artificial nail,consequently diffuses a pepper spray,and automatically notifies the saved closest contacts and police station through messaging and location *** has a response time of 1000 ms once the nail is pressed;the average time for pulse rate measure is 0.475 s,and diffusing the pepper spray is 0.2–0.5 *** average activation time is 2.079 s.
Pattern-based, password-based, and PIN-based authentication techniques are typically the most common among smartphone users. However, according to prior studies these authentication techniques are susceptible to keylo...
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The classification of harmful brain activities, such as seizures and periodic discharges, play a vital role in neurocritical care, enabling timely diagnosis and intervention. Electroencephalography (EEG) provides a no...
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