This study addresses the shortcomings in diagnosing and managing HCM (Hypertrophic Cardiomyopathy), a genetic heart disease affecting 0.5-1.5% of the global population, by employing advanced ML (Machine Learning) appr...
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ISBN:
(数字)9798331521691
ISBN:
(纸本)9798331521707
This study addresses the shortcomings in diagnosing and managing HCM (Hypertrophic Cardiomyopathy), a genetic heart disease affecting 0.5-1.5% of the global population, by employing advanced ML (Machine Learning) approaches. The research integrates multimodal data, including cardiac MRI, genetic, clinical, and outcome information, to design and implement interpretable ML models capable of diagnosing HCM, assessing disease progression, and indicating individualized treatment courses. To enhance generalization and facilitate clinical application, a large multi-center dataset is utilized. Results demonstrate that the developed ML models achieve higher accuracy in HCM diagnosis and risk stratification compared to traditional methods, with particular strength in early detection and prognosis prediction. This work not only aims to improve care for HCM patients but also establishes a foundation for applying ML algorithms to other complex genetic cardiac diseases, potentially shifting the paradigm of cardiovascular medicine towards a more targeted approach. The findings suggest significant potential for improving patient outcomes through personalized treatment strategies and more accurate risk evaluation, setting the stage for further research into ML applications in complex cardiovascular disorders and potentially revolutionizing precision medicine in cardiology.
In the rapidly advancing field of bioinformatics, sequence alignment is a pivotal task for elucidating genetic statistics and evolutionary relationships. As the volume and complexity of biological data continue to gro...
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With constant hardware improvements allowing for increasingly large memory sizes, in-memory database servers have become an attractive option for various cloud applications. Even though in-memory database servers stor...
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State-space graphs and automata serve as fundamental tools for modeling and analyzing the behavior of computational systems. Recurrent neural networks (RNNs) and language models are deeply intertwined, as RNNS provide...
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State-space graphs and automata serve as fundamental tools for modeling and analyzing the behavior of computational systems. Recurrent neural networks (RNNs) and language models are deeply intertwined, as RNNS provide the foundational architecture that enables language models to process sequential data, capture contextual dependencies, and improve natural language processing tasks. Both RNNs and state-space graphs help evaluate discrete-time systems within this formal framework. However, the basic question of their equivalence remains an open challenge regarding the models governing sentence structure in natural language and the formal model in automata theory. In this paper, we present ENGRU (Enhanced Gated Recurrent Units), a novel deep learning-based approach for formal verification. ENGRU integrates concepts of model checking techniques, Colored Petri Nets (CPNs), and sequential learning to analyze systems at a high level of abstraction. CPN models undergo state-space enumeration via a model-checking tool, generating a state-space graph and an automaton from inherent state transition patterns. These graphs are transformed into sequential representations as sub-paths, enabling ENGRU to learn the execution paths and predict system behaviors. ENGRU effectively predicts goal states within discrete-time models by the competency of gated recurrent mechanisms, encouraging early bug detection and allowing predictive state-space exploration. Experimental results demonstrate that ENGRU’s ability achieves high accuracy and efficiency in goal state predictions. The source code for ENGRU is available at ( https://***/kaopanboonyuen/ENGRU ).
Secure inference of deep convolutional neural networks (CNNs) under RNS-CKKS involves polynomial approximation of unsupported non-linear activation functions. However, existing approaches have three main limitations: ...
ISBN:
(纸本)9781939133441
Secure inference of deep convolutional neural networks (CNNs) under RNS-CKKS involves polynomial approximation of unsupported non-linear activation functions. However, existing approaches have three main limitations: 1) Inflexibility: The polynomial approximation and associated homomorphic evaluation architecture are customized manually for each CNN architecture and do not generalize to other networks. 2) Suboptimal Approximation: Each activation function is approximated instead of the function represented by the CNN. 3) Restricted Design: Either high-degree or low-degree polynomial approximations are used. The former retains high accuracy but slows down inference due to bootstrapping operations, while the latter accelerates ciphertext inference but compromises accuracy. To address these limitations, we present AutoFHE, which automatically adapts standard CNNs for secure inference under RNS-CKKS. The key idea is to adopt lay-erwise mixed-degree polynomial activation functions, which are optimized jointly with the homomorphic evaluation architecture in terms of the placement of bootstrapping operations. The problem is modeled within a multi-objective optimization framework to maximize accuracy and minimize the number of bootstrapping operations. AutoFHE can be applied flexibly on any CNN architecture, and it provides diverse solutions that span the trade-off between accuracy and latency. Experimental evaluation over RNS-CKKS encrypted CIFAR datasets shows that AutoFHE accelerates secure inference by 1.32× to 1.8× compared to methods employing high-degree polynomials. It also improves accuracy by up to 2.56% compared to methods using low-degree polynomials. Lastly, AutoFHE accelerates inference and improves accuracy by 103× and 3.46%, respectively, compared to CNNs under TFHE.
We propose and demonstrate a data-driven plasmonic metascreen that efficiently absorbs incident light over a wide spectral range in an ultra-thin silicon *** embedding a double-nanoring silver array within a 20 nm ult...
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We propose and demonstrate a data-driven plasmonic metascreen that efficiently absorbs incident light over a wide spectral range in an ultra-thin silicon *** embedding a double-nanoring silver array within a 20 nm ultrathin amorphous silicon(a-Si)layer,we achieve a significant enhancement of light *** enhancement arises from the interaction between the resonant cavity modes and localized plasmonic modes,requiring precise tuning of plasmon resonances to match the absorption region of the silicon active *** facilitate the device design and improve light absorption without increasing the thickness of the active layer,we develop a deep learning framework,which learns to map from the absorption spectra to the design *** inverse design strategy helps to tune the absorption for selective spectral *** optimized design surpasses the bare silicon planar device,exhibiting a remarkable enhancement of over 100%.Experimental validation confirms the broadband enhancement of light absorption in the proposed *** proposed metascreen absorber holds great potential for light harvesting applications and may be leveraged to improve the light conversion efficiency of ultra-thin silicon solar cells,photodetectors,and optical filters.
Reducing the availability of spectrum, as well as the nature of allocating channels in the present wireless telecommunication networks, is one of the critical issues facing modern wireless technology. Such spectrum se...
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Loans are the bank’s assets since they generate income in terms of interest to banks. Lending a loan to a customer creates credit and liability for the bank and the customer. The profit and loss of a bank depend on t...
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Loans are the bank’s assets since they generate income in terms of interest to banks. Lending a loan to a customer creates credit and liability for the bank and the customer. The profit and loss of a bank depend on the customer’s ability to pay back the loan or not, i.e., defaulter or not. Therefore, predicting the probability of loan repayment becomes a crucial task. For this purpose, ensemble learning methods have been incorporated extensively, and studies have reported the superiority of these methods over conventional classification methods. This paper provides a comprehensive comparative performance assessment of various ensemble methods for predicting Loan approval in the banking sector. Ensemble algorithms, including bagging, boosting and stacking, are considered with the Neural Network (NN), Decision Tree (DT), Logistic Regression (LR), Naive Bayes (NB), and Support Vector Machine (SVM) as baseline classifiers, which are regarded as benchmarks. The quantitative analysis has been presented in terms of accu- racy (ACC), Receiver Operating characteristic Curve (ROC), Area Under the Curve (AUC), Kolmogorov-Smirnov Statistic (KS), Cohen’s Kappa Score (CKS), and Brier Score (BS). The experimental results affirm that ensemble learning performs better than individual learning. LR outperforms other baseline classifiers, whereas the RF (bagging DT) performs the best among the ensemble approaches, followed by XGB and LightGBM, respectively.
As one of the most essential accessories, headsets have been widely used in common online conversations. The metal coil vibration patterns of headset speakers/microphones have been proven to be highly correlated with ...
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The increasing adoption of Electric Vehicles (EVs) necessitates advanced charging infrastructure. This manuscript presents a novel approach that integrates Graph Convolutional Networks (GCNs) and the Deep Dyna Reinfor...
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