A1 Functional advantages of cell-type heterogeneity in neural circuits Tatyana O. Sharpee A2 Mesoscopic modeling of propagating waves in visual cortex Alain Destexhe A3 Dynamics and biomarkers of mental disorders Mits...
A1 Functional advantages of cell-type heterogeneity in neural circuits Tatyana O. Sharpee A2 Mesoscopic modeling of propagating waves in visual cortex Alain Destexhe A3 Dynamics and biomarkers of mental disorders Mitsuo Kawato F1 Precise recruitment of spiking output at theta frequencies requires dendritic h-channels in multi-compartment models of oriens-lacunosum/moleculare hippocampal interneurons Vladislav Sekulić, Frances K. Skinner F2 Kernel methods in reconstruction of current sources from extracellular potentials for single cells and the whole brains Daniel K. Wójcik, Chaitanya Chintaluri, Dorottya Cserpán, Zoltán Somogyvári F3 The synchronized periods depend on intracellular transcriptional repression mechanisms in circadian clocks. Jae Kyoung Kim, Zachary P. Kilpatrick, Matthew R. Bennett, Kresimir Josić O1 Assessing irregularity and coordination of spiking-bursting rhythms in central pattern generators Irene Elices, David Arroyo, Rafael Levi, Francisco B. Rodriguez, Pablo Varona O2 Regulation of top-down processing by cortically-projecting parvalbumin positive neurons in basal forebrain Eunjin Hwang, Bowon Kim, Hio-Been Han, Tae Kim, James T. McKenna, Ritchie E. Brown, Robert W. McCarley, Jee Hyun Choi O3 Modeling auditory stream segregation, build-up and bistability James Rankin, Pamela Osborn Popp, John Rinzel O4 Strong competition between tonotopic neural ensembles explains pitch-related dynamics of auditory cortex evoked fields Alejandro Tabas, André Rupp, Emili Balaguer-Ballester O5 A simple model of retinal response to multi-electrode stimulation Matias I. Maturana, David B. Grayden, Shaun L. Cloherty, Tatiana Kameneva, Michael R. Ibbotson, Hamish Meffin O6 Noise correlations in V4 area correlate with behavioral performance in visual discrimination task Veronika Koren, Timm Lochmann, Valentin Dragoi, Klaus Obermayer O7 Input-location dependent gain modulation in cerebellar nucleus neurons Maria Psarrou, Maria Schilstra, Neil Davey, Benjamin Torben-Ni
Transcriptomic imputation approaches combine eQTL reference panels with large-scale genotype data in order to test associations between disease and gene expression. These genic associations could elucidate signals in ...
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Transcriptomic imputation approaches combine eQTL reference panels with large-scale genotype data in order to test associations between disease and gene expression. These genic associations could elucidate signals in complex genome-wide association study (GWAS) loci and may disentangle the role of different tissues in disease development. We used the largest eQTL reference panel for the dorso-lateral prefrontal cortex (DLPFC) to create a set of gene expression predictors and demonstrate their utility. We applied DLPFC and 12 GTEx-brain predictors to 40,299 schizophrenia cases and 65,264 matched controls for a large transcriptomic imputation study of schizophrenia. We identified 413 genic associations across 13 brain regions. Stepwise conditioning identified 67 non-MHC genes, of which 14 did not fall within previous GWAS loci. We identified 36 significantly enriched pathways, including hexosaminidase-A deficiency, and multiple porphyric disorder pathways. We investigated developmental expression patterns among the 67 non-MHC genes and identified specific groups of pre- and postnatal expression.
Enterprise governance basically is a framework, principles and policies, structures, processes and practices, information, skills, culture, ethics, and behavior to determine direction and monitoring related to complia...
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Enterprise governance basically is a framework, principles and policies, structures, processes and practices, information, skills, culture, ethics, and behavior to determine direction and monitoring related to compliance and performance that align with enterprise goals. COBIT 5 provides guidance that enterprise governance is influenced by individual and collective factors. The existence of this factor will influence process ini scope of governance enterprise either for governance and management area. University governance is a behavior, manner or method used by the college to utilize full potential and optimization elements, in order to achieve the vision and mission that has been set. Model of Vocational University Governance are built based on governance university components and principles of good university governance with reference models that exist within ISO 38500 framework. Enablers that exist within COBIT 5 framework will be used as a determining factor in the preparation of the proposed model of governance and measurement model of vocational university governance.
Robots also have been trusted to help human to complete difficult jobs, for example, finding for the earthquake, a fire, or a sinking ship victims. The robot must be reliable, clever and moving automatically. The aim ...
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Robots also have been trusted to help human to complete difficult jobs, for example, finding for the earthquake, a fire, or a sinking ship victims. The robot must be reliable, clever and moving automatically. The aim of this study is to develop and apply the application of artificial RAM-based neural networks (WNNs) on a mobile robot using a multilayer processing architecture with memory optimizations on to address and input pattern, so that producing smart navigation model which it has a simpler computational load and faster execution time. The gained result from the first study was the percentage of memory optimization in the amount of 50%. This result obtained from the formerly RAM using 8 bit data width has been optimized to 4 bits. Both of the percentage of data optimization pattern is 93.75%. This percentage is obtained from the optimization pattern (pattern taken is 4 bits MSB), each 1 bit data can handle 15 unseen patterns.
Organic Transistor (OT) modeling, fabrication and applicability has undergone remarkable progress during last ten years. Organic Thin Film Transistors (OTFTs) have received significant attention recently because of th...
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To investigate the genetic basis of type 2 diabetes (T2D) to high resolution, the GoT2D and T2D-GENES consortia catalogued variation from whole-genome sequencing of 2,657 European individuals and exome sequencing of 1...
To investigate the genetic basis of type 2 diabetes (T2D) to high resolution, the GoT2D and T2D-GENES consortia catalogued variation from whole-genome sequencing of 2,657 European individuals and exome sequencing of 12,940 individuals of multiple ancestries. Over 27M SNPs, indels, and structural variants were identified, including 99% of low-frequency (minor allele frequency [MAF] 0.1-5%) non-coding variants in the whole-genome sequenced individuals and 99.7% of low-frequency coding variants in the whole-exome sequenced individuals. Each variant was tested for association with T2D in the sequenced individuals, and, to increase power, most were tested in larger numbers of individuals (>80% of low-frequency coding variants in ~82 K Europeans via the exome chip, and ~90% of low-frequency non-coding variants in ~44 K Europeans via genotype imputation). The variants, genotypes, and association statistics from these analyses provide the largest reference to date of human genetic information relevant to T2D, for use in activities such as T2D-focused genotype imputation, functional characterization of variants or genes, and other novel analyses to detect associations between sequence variation and T2D.
A1 Introduction to the 8th Annual Conference on the Science of Dissemination and Implementation: Optimizing Personal and Population Health David Chambers, Lisa Simpson D1 Discussion forum: Population health D&...
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A1 Introduction to the 8th Annual Conference on the Science of Dissemination and Implementation: Optimizing Personal and Population Health David Chambers, Lisa Simpson D1 Discussion forum: Population health D&I research Felicia Hill-Briggs D2 Discussion forum: Global health D&I research Gila Neta, Cynthia Vinson D3 Discussion forum: Precision medicine and D&I research David Chambers S1 Predictors of community therapists’ use of therapy techniques in a large public mental health system Rinad Beidas, Steven Marcus, Gregory Aarons, Kimberly Hoagwood, Sonja Schoenwald, Arthur Evans, Matthew Hurford, Ronnie Rubin, Trevor Hadley, Frances Barg, Lucia Walsh, Danielle Adams, David Mandell S2 Implementing brief cognitive behavioral therapy (CBT) in primary care: Clinicians' experiences from the field Lindsey Martin, Joseph Mignogna, Juliette Mott, Natalie Hundt, Michael Kauth, Mark Kunik, Aanand Naik, Jeffrey Cully S3 Clinician competence: Natural variation, factors affecting, and effect on patient outcomes Alan McGuire, Dominique White, Tom Bartholomew, John McGrew, Lauren Luther, Angie Rollins, Michelle Salyers S4 Exploring the multifaceted nature of sustainability in community-based prevention: A mixed-method approach Brittany Cooper, Angie Funaiole S5 Theory informed behavioral health integration in primary care: Mixed methods evaluation of the implementation of routine depression and alcohol screening and assessment Julie Richards, Amy Lee, Gwen Lapham, Ryan Caldeiro, Paula Lozano, Tory Gildred, Carol Achtmeyer, Evette Ludman, Megan Addis, Larry Marx, Katharine Bradley S6 Enhancing the evidence for specialty mental health probation through a hybrid efficacy and implementation study Tonya VanDeinse, Amy Blank Wilson, Burgin Stacey, Byron Powell, Alicia Bunger, Gary Cuddeback S7 Personalizing evidence-based child mental health care within a fiscally mandated policy reform Miya Barnett, Nicole Stadnick, Lauren Brookman-Frazee, Anna Lau S8 Leveraging an existing
The integration of wind turbines into modern power grids has significantly increased during the last decade. The wind turbine equipped with full converter based wind energy Conversion System (FCWECS) represented about...
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The integration of wind turbines into modern power grids has significantly increased during the last decade. The wind turbine equipped with full converter based wind energy Conversion System (FCWECS) represented about 20.3% of the worldwide total wind capacity in 2003. Since FCWECS is equipped with a voltage source inverter (VSI), it is vulnerable that misfire and fire-through may occur within the VSI switches. In this paper, impact of these switching malfunctions on FCWECS performance is investigated and discussed. Detailed simulations of the system under study are carried out using Matlab/Simulink to highlight the influence of these converter internal faults on PCC voltage, DC link voltage and shaft speed, as well as generator active and reactive power. Furthermore, compliance of the FCWECS with Spain fault ride through (FRT) grid codes is also investigated.
Variable speed wind turbine generators installation has been significantly increased worldwide in the last few years. Voltage sag at the grid side may call for the disconnection of the wind turbine from the grid as un...
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Variable speed wind turbine generators installation has been significantly increased worldwide in the last few years. Voltage sag at the grid side may call for the disconnection of the wind turbine from the grid as under such faults it may not comply with the recent developed grid codes for wind energy conversion systems (WECS). In this paper, a Unified Power Flow Controller (UPFC) is applied to improve the low voltage ride through (LVRT) capability of doubly fed induction generator (DFIG)-based WECS during voltage sag at the grid side. Simulation is carried out using MATLAB/Simulink software. Results show that UPFC can significantly improve the LVRT capability of DFIG-based WECS and hence maintaining wind turbine connection to the grid during certain levels of voltage sag at the grid side.
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