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Publisher Correction: Transcriptomic alterations during ageing reflect the shift from cancer to degenerative diseases in the elderly

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Nature communications 2019年第1期10卷 2459页

作者： Peer Aramillo Irizar Sascha Schäuble Daniela Esser Marco Groth Christiane Frahm Steffen Priebe Mario Baumgart Nils Hartmann Shiva Marthandan Uwe Menzel Jule Müller Silvio Schmidt Volker Ast Amke Caliebe Rainer König Michael Krawczak Michael Ristow Stefan Schuster Alessandro Cellerino Stephan Diekmann Christoph Englert Peter Hemmerich Jürgen Sühnel Reinhard Guthke Otto W Witte Matthias Platzer Eytan Ruppin Christoph Kaleta Research Group Medical Systems Biology Institute of Experimental Medicine Christian-Albrechts-University Kiel D-24105 Kiel Germany. Jena University Language and Information Engineering Lab Friedrich-Schiller-University Jena D-07743 Jena Germany. GerontoSys JenAge Consortium D-07745 Jena Germany. Genome Analysis Lab Leibniz Institute on Aging-Fritz-Lipmann-Institute D-07745 Jena Germany. Hans Berger Department of Neurology Jena University Hospital D-07747 Jena Germany. Systems Biology and Bioinformatics Group Leibniz Institute for Natural Product Research and Infection Biology-Hans-Knöll-Institute D-07745 Jena Germany. Biology of Ageing Lab Leibniz Institute on Aging-Fritz-Lipmann-Institute D-07745 Jena Germany. Molecular Genetics Lab Leibniz Institute on Aging-Fritz-Lipmann-Institute D-07745 Jena Germany. Imageing Facility Leibniz Institute on Aging-Fritz-Lipmann-Institute D-07745 Jena Germany. Integrated Research and Treatment Center Center for Sepsis Control and Care (CSCC) Jena University Hospital D-07747 Jena Germany. Network Modeling Leibniz Institute for Natural Product Research and Infection Biology-Hans Knöll Institute D-07745 Jena Germany. Institute for Medical Informatics and Statistics Christian-Albrechts-University Kiel D-24105 Kiel Germany. Energy Metabolism Laboratory Swiss Federal Institute of Technology (ETH) Zurich Schwerzenbach/Zürich CH-8603 Switzerland. Department of Bioinformatics Friedrich-Schiller-University Jena D-07743 Jena Germany. Laboratory of Neurobiology Scuola Normale Superiore University of Pisa I-56100 Pisa Italy. Molecular Biology Lab Leibniz Institute on Aging-Fritz-Lipmann-Institute D-07745 Jena Germany. Faculty of Biology and Pharmacy Friedrich-Schiller-University Jena D-07743 Jena Germany. Biocomputing Lab Leibniz Institute on Aging-Fritz-Lipmann-Institute D-07745 Jena Germany. Department of Computer Science and Center for Bioinformatics and Computational Biology University of Maryland College Park M

The original version of this Article contained an error in the spelling of the author Jule Müller, which was incorrectly given as Julia Müller. Additionally, in Fig. 4a, the blue-red colour scale for fold change in ageing/disease regulation included a blue stripe in place of a red stripe at the right-hand end of the scale. These errors have been corrected in both the PDF and HTML versions of the Article.

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26th Annual computational Neuroscience Meeting (CNS*2017): Part 3 Antwerp, Belgium. 15-20 July 2017 Abstracts

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BMC NEUROSCIENCE 2017年第SUPPL 1期18卷 95-176页

作者： [Anonymous] Department of Neuroscience Yale University New Haven CT 06520 USA Department Physiology & Pharmacology SUNY Downstate Brooklyn NY 11203 USA NYU School of Engineering 6 MetroTech Center Brooklyn NY 11201 USA Departament de Matemàtica Aplicada Universitat Politècnica de Catalunya Barcelona 08028 Spain Institut de Neurobiologie de la Méditerrannée (INMED) INSERM UMR901 Aix-Marseille Univ Marseille France Center of Neural Science New York University New York NY USA Aix-Marseille Univ INSERM INS Inst Neurosci Syst Marseille France Laboratoire de Physique Théorique et Modélisation CNRS UMR 8089 Université de Cergy-Pontoise 95300 Cergy-Pontoise Cedex France Department of Mathematics and Computer Science ENSAT Abdelmalek Essaadi’s University Tangier Morocco Laboratory of Natural Computation Department of Information and Electrical Engineering and Applied Mathematics University of Salerno 84084 Fisciano SA Italy Department of Medicine University of Salerno 84083 Lancusi SA Italy Dipartimento di Fisica Università degli Studi Aldo Moro Bari and INFN Sezione Di Bari Italy Data Analysis Department Ghent University Ghent Belgium Coma Science Group University of Liège Liège Belgium Cruces Hospital and Ikerbasque Research Center Bilbao Spain BIOtech Department of Industrial Engineering University of Trento and IRCS-PAT FBK 38010 Trento Italy Department of Data Analysis Ghent University Ghent 9000 Belgium The Wellcome Trust Centre for Neuroimaging University College London London WC1N 3BG UK Department of Electronic Engineering NED University of Engineering and Technology Karachi Pakistan Blue Brain Project École Polytechnique Fédérale de Lausanne Lausanne Switzerland Departement of Mathematics Swansea University Swansea Wales UK Laboratory for Topology and Neuroscience at the Brain Mind Institute École polytechnique fédérale de Lausanne Lausanne Switzerland Institute of Mathematics University of Aberdeen Aberdeen Scotland UK Department of Integrativ

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26th Annual computational Neuroscience Meeting (CNS*2017) of the Organization for computational Neuroscience Antwerp, Belgium, July 15-20, 2017

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BMC NEUROSCIENCE 2017年第SUPPL 1期18卷 59-59页

作者： [Anonymous] Indiana University Purdue University Indianapolis Indianapolis IN 46032 USA Stark Neurosciences Research Institute Indiana University School of Medicine Indianapolis IN 46032 USA Department of Mathematics East Carolina University Greenville NC 27858 USA Jülich Supercomputing Centre Forschungszentrum Jülich 52425 Jülich Germany Future Systems Swiss National Supercomputing Centre 8092 Zurich Switzerland User Engagement and Support Swiss National Supercomputing Centre 6900 Lugano Switzerland Institut de Neurosciences des Systèmes Aix Marseille Univ 13005 Marseille France Simulation Lab Neuroscience Forschungszentrum Jülich Jülich Germany Department of Experimental Psychology Ghent University 9000 Ghent Belgium Donders Center for Cognitive Neuroimaging Radboud University 6525HR Nijmegen The Netherlands Department of Electrical Computer and Energy Engineering University of Colorado Boulder CO 80309 USA Department of Neurosurgery Johns Hopkins School of Medicine Baltimore MD 21287 USA Department of Neurology Johns Hopkins School of Medicine Baltimore MD 21287 USA Department of Otolaryngology Johns Hopkins School of Medicine Baltimore MD 21287 USA INSERM U968 Paris France Sorbonne Universités UPMC University Paris 06 UMR_S 968 Institut de la Vision Paris France CNRS UMR_7210 Paris France Department of Computer Architecture and Technology University of Granada (CITIC) Granada Spain Sorbonne Universités UPMC Univ Paris 06 INSERM CNRS Institut de la Vision Paris France Department of Adaptive Machine Systems Osaka University Osaka Japan Department of Computer Science University of Cergy-Pontoise Cergy-Pontoise France Department of Physics and Astronomy College of Charleston Charleston SC 29424 USA School of Physics Faculty of Science University of Sydney Sydney NSW 2006 Australia Center of Excellence for Integrative Brain Function Australian Research Council Sydney Australia Max Planck Institute for Human Cognitive and Brain Sciences Saxony Lei

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The atacama cosmology telescope: Component-separated maps of CMB temperature and the thermal Sunyaev-Zel'dovich effect

arXiv

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arXiv 2019年

作者： Madhavacheril, Mathew S. Hill, J. Colin Nss, Sigurd Addison, Graeme E. Aiola, Simone Baildon, Taylor Battaglia, Nicholas Bean, Rachel Bond, J. Richard Calabrese, Erminia Calafut, Victoria Choi, Steve K. Darwish, Omar Devlin, Mark J. Dunkley, Joanna Dunner, Rolando Ferraro, Simone Gallardo, Patricio A. Halpern, Mark Han, Dongwon Hasseleld, Matthew Hilton, Matt Hincks, Adam D. Hlozek, Renee Ho, Shuay-Pwu Patty Huffenberger, Kevin M. Hughes, John P. Koopman, Brian J. Kosowsky, Arthur Lokken, Martine Louis, Thibaut Lungu, Marius MacInnis, Amanda Maurin, Loic McMahon, Jeffrey J. Moodley, Kavilan Nati, Federico Niemack, Michael D. Page, Lyman A. Partridge, Bruce Robertson, Naomi Sehgal, Neelima Schaan, Emmanuel Schillaci, Alessandro Sherwin, Blake D. Sifon, Cristobal Simon, Sara M. Spergel, David N. Staggs, Suzanne T. Storer, Emilie R. van Engelen, Alexander Vavagiakis, Eve M. Wollack, Edward J. Xu, Zhilei Centre for the Universe Perimeter Institute for Theoretical Physics WaterlooONN2L2Y5 Canada Department of Astrophysical Sciences Princeton University 4 Ivy Lane PrincetonNJ08544 United States Department of Physics Columbia University 550 West 120th Street New YorkNY10027 United States Center for Computational Astrophysics Flatiron Institute 162 5th Avenue New YorkNY10010 United States School of Natural Sciences Institute for Advanced Study PrincetonNJ08540 United States Department of Physics and Astronomy Johns Hopkins University BaltimoreMD21218 United States Department of Physics University of Michigan Ann Arbor48103 United States Department of Astronomy Cornell University IthacaNY14853 United States Canadian Institute for Theoretical Astrophysics University of Toronto 60 St. George St. TorontoONM5S3H8 Canada School of Physics and Astronomy Cardiff University Parade CardiffCF243AA United Kingdom Department of Applied Mathematics and Theoretical Physics University of Cambridge Wilberforce Road CambridgeCB30WA United Kingdom Department of Physics and Astronomy University of Pennsylvania 209 South 33rd Street PhiladelphiaPA19104 United States Joseph Henry Laboratories of Physics Jadwin Hall Princeton University PrincetonNJ08544 United States Instituto de Astrofisica Centro de Astro-Ingenieria Facultad de Fisica Ponticia Universidad Catolica de Chile Av. Vicuna Mackenna 4860 Macul Santiago7820436 Physics Division Lawrence Berkeley National Laboratory BerkeleyCA94720 United States Department of Physics Cornell University 109 Clark Hall IthacaNY14853 United States Department of Physics and Astronomy University of British Columbia VancouverBCV6T1Z1 Canada Physics and Astronomy Department Stony Brook University Stony BrookNY11794 United States Astrophysics & Cosmology Research Unit School of Mathematics Statistics & Computer Science University of KwaZulu-Natal Westville Campus Durban4041 South Africa Department of A

Optimal analyses of many signals in the cosmic microwave background (CMB) require maplevel extraction of individual components in the microwave sky, rather than measurements at the power spectrum level alone. To date, nearly all map-level component separation in CMB analyses has been performed exclusively using satellite data. In this paper, we implement a component separation method based on the internal linear combination (ILC) approach which we have designed to optimally account for the anisotropic noise (in the 2D Fourier domain) often found in groundbased CMB experiments. Using this method, we combine multi-frequency data from the Planck satellite and the Atacama Cosmology Telescope Polarimeter (ACTPol) to construct the first widearea, arcminute-resolution component-separated maps (covering ≈ 2100 sq. deg.) of the CMB temperature anisotropy and the thermal Sunyaev-Zel'dovich (tSZ) effect sourced by the inverse-Compton scattering of CMB photons off hot, ionized gas. Our ILC pipeline allows for explicit deprojection of various contaminating signals, including a modified blackbody approximation of the cosmic infrared background (CIB) spectral energy distribution. The cleaned CMB maps will be a useful resource for CMB lensing reconstruction, kinematic SZ cross-correlations, and primordial non-Gaussianity studies. The tSZ maps will be used to study the pressure profiles of galaxies, groups, and clusters through cross-correlations with halo catalogs, with dust contamination controlled via CIB deprojection. The data products described in this paper will be made available on LAMBDA. Copyright © 2019, The Authors. All rights reserved.

关键词： Cosmology

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The cluster heritage project with XMM-Newton: Mass assembly and thermodynamics at the endpoint of structure formation I. Programme overview

arXiv

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arXiv 2020年

作者： Arnaud, M. Ettori, S. Pratt, Gabriel W. Rossetti, M. Eckert, D. Gastaldello, F. Gavazzi, R. Kay, S.T. Lovisari, L. Maughan, B.J. Pointecouteau, E. Sereno, M. Bartalucci, I. Bonafede, A. Bourdin, H. Cassano, R. Duffy, R.T. Iqbal, A. Maurogordato, S. Rasia, E. Sayers, J. Andrade-Santos, F. Aussel, H. Barnes, D.J. Barrena, R. Borgani, S. Burkutean, S. Clerc, N. Corasaniti, P.-S. Cuillandre, J.-C. de Grandi, S. de Petris, M. Dolag, K. Donahue, M. Ferragamo, A. Gaspari, M. Ghizzardi, S. Gitti, M. Haines, C.P. Jauzac, M. Johnston-Hollitt, M. Jones, C. Kéruzoré, F. LeBrun, A.M.C. Mayet, F. Mazzotta, P. Melin, J.-B. Molendi, S. Nonino, M. Okabe, N. Paltani, S. Perotto, L. Pires, S. Radovich, M. Rubino-Martin, J.-A. Salvati, L. Saro, A. Sartoris, B. Schellenberger, G. Streblyanska, A. Tarrío, P. Tozzi, P. Umetsu, K. van der Burg, R.F.J. Vazza, F. Venturi, T. Yepes, G. Zarattini, S. AIM CEA CNRS Université Paris-Saclay Université Paris Diderot Sorbonne Paris Cité Gif-sur-YvetteF-91191 France INAF Osservatorio di Astrofisica e Scienza dello Spazio via Pietro Gobetti 93/3 Bologna40129 Italy INFN Sezione di Bologna viale Berti Pichat 6/2 BolognaI-40127 Italy INAF IASF-Milano via A. Corti 12 MilanoI-20133 Italy Department of Astronomy University of Geneva ch. d'Écogia 16 VersoixCH-1290 Switzerland CNRS Sorbonne Université UMR 7095 Institut d'Astrophysique de Paris 98 bis Boulevard Arago Paris75014 France Jodrell Bank Centre for Astrophysics Department of Physics and Astronomy School of Natural Sciences The University of Manchester ManchesterM13 9PL United Kingdom Center for Astrophysics | Harvard & Smithsonian 60 Garden Street CambridgeMA02138 United States HH Wills Physics Laboratory University of Bristol Tyndall Ave BristolBS8 1TL United Kingdom IRAP Université de Toulouse CNRS CNES UPS 9 av du colonel Roche BP44346 Toulouse Cedex 431028 France Dipartimento di Fisica e Astronomia Universitá di Bologna Via Gobetti 92/3 Bologna40121 Italy INAF Istituto di Radio Astronomia Via Gobetti 101 Bologna40129 Italy Hamburger Sternwarte Gojenbergsweg 112 Hamburg21029 Germany Università degli studi di Roma Tor Vergata via della ricerca scientifica 1 Roma00133 Italy Université Côte d'Azur Observatoire de la Côte d'Azur CNRS Laboratoire Lagrange Nice France INAF - Osservatorio Astronomico di Trieste via Tiepolo 11 TriesteI-34131 Italy IFPU - Institute for Fundamental Physics of the Universe via Beirut 2 Trieste34151 Italy California Institute of Technology PasadenaCA91125 United States Department of Physics Kavli Institute for Astrophysics and Space Research Massachusetts Institute of Technology CambridgeMA02139 United States C/ Vía Láctea s/n La Laguna TenerifeE-38205 Spain Universidad de La Laguna Departamento de Astrofísica C/ Astrofísico Francisco Sánchez s/n La Laguna TenerifeE-38206 Spain D

The Cluster HEritage project with XMM-Newton - Mass Assembly and Thermodynamics at the Endpoint of structure formation (CHEX-MATE) is a three-mega-second Multi-Year Heritage Programme to obtain X-ray observations of a minimally-biased, signal-to-noise-limited sample of 118 galaxy clusters detected by Planck through the Sunyaev-Zeldovich effect. The programme, described in detail in this paper, aims to study the ultimate products of structure formation in time and mass. It is composed of a census of the most recent objects to have formed (Tier-1: 0.05 14 M 500 14 M), together with a sample of the highest mass objects in the Universe (Tier-2: z 500 > 7.25 × 1014 M). The programme will yield an accurate vision of the statistical properties of the underlying population, measure how the gas properties are shaped by collapse into the dark matter halo, uncover the provenance of non-gravitational heating, and resolve the major uncertainties in mass determination that limit the use of clusters for cosmological parameter estimation. We will acquire X-ray exposures of uniform depth, designed to obtain individual mass measurements accurate to 15 − 20% under the hydrostatic assumption. We present the project motivations, describe the programme definition, and detail the ongoing multi-wavelength observational (lensing, SZ, radio) and theoretical effort that is being deployed in support of the project. Copyright © 2020, The Authors. All rights reserved.

关键词： Thermodynamics

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Characterizing the inverses of block tridiagonal, block Toeplitz matrices

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computational Science and Discovery 2015年第1期8卷

作者： Boffi, Nicholas M. Hill, Judith C. Reuter, Matthew G. Center for Nanophase Materials Sciences Oak Ridge National Laboratory Oak RidgeTN37831 United States National Center for Computational Sciences Oak Ridge National Laboratory Oak RidgeTN37831 United States Computer Science and Mathematics Division Oak Ridge National Laboratory Oak RidgeTN37831 United States Department of Applied Mathematics and Statistics Institute for Advanced Computational Science Stony Brook University Stony BrookNY11794 United States

We consider the inversion of block tridiagonal, block Toeplitz matrices and comment on the behaviour of these inverses as one moves away from the diagonal. Using matrix Möbius transformations, we first present an O(1) representation (with respect to the number of block rows and block columns) for the inverse matrix and subsequently use this representation to characterize the inverse matrix. There are four symmetry-distinct cases where the blocks of the inverse matrix (i) decay to zero on both sides of the diagonal, (ii) oscillate on both sides, (iii) decay on one side and oscillate on the other and (iv) decay on one side and grow on the other. This characterization exposes the necessary conditions for the inverse matrix to be numerically banded and may also aid in the design of preconditioners and fast algorithms. Finally, we present numerical examples of these matrix types. © 2015 IOP Publishing Ltd.

关键词： Matrix algebra

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Planck 2018 results. IX. Constraints on primordial non-Gaussianity

arXiv

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arXiv 2019年

作者： Akrami, Y. Arroja, F. Ashdown, M. Aumont, J. Baccigalupi, C. Ballardini, M. Banday, A.J. Barreiro, R.B. Bartolo, N. Basak, S. Benabed, K. Bernard, J.-P. Bersanelli, M. Bielewicz, P. Bond, J.R. Borrill, J. Bouchet, F.R. Bucher, M. Burigana, C. Butler, R.C. Calabrese, E. Cardoso, J.-F. Casaponsa, B. Challinor, A. Chiang, H.C. Colombo, L.P.L. Combet, C. Crill, B.P. Cuttaia, F. de Bernardis, P. de Rosa, A. de Zotti, G. Delabrouille, J. Delouis, J.-M. Di Valentino, E. Diego, J.M. Doré, O. Douspis, M. Ducout, A. Dupac, X. Dusini, S. Efstathiou, G. Elsner, F. Enßlin, T.A. Eriksen, H.K. Fantaye, Y. Fergusson, J. Fernandez-Cobos, R. Finelli, F. Frailis, M. Fraisse, A.A. Franceschi, E. Frolov, A. Galeotta, S. Ganga, K. Génova-Santos, R.T. Gerbino, M. González-Nuevo, J. Górski, K.M. Gratton, S. Gruppuso, A. Gudmundsson, J.E. Hamann, J. Handley, W. Hansen, F.K. Herranz, D. Hivon, E. Huang, Z. Jaffe, A.H. Jones, W.C. Jung, G. Keihänen, E. Keskitalo, R. Kiiveri, K. Kim, J. Krachmalnicoff, N. Kunz, M. Kurki-Suonio, H. Lamarre, J.-M. Lasenby, A. Lattanzi, M. Lawrence, C.R. Le Jeune, M. Levrier, F. Lewis, A. Liguori, M. Lilje, P.B. Lindholm, V. López-Caniego, M. Ma, Y.-Z. Macías-Pérez, J.F. Maggio, G. Maino, D. Mandolesi, N. Marcos-Caballero, A. Maris, M. Martin, P.G. Martínez-González, E. Matarrese, S. Mauri, N. McEwen, J.D. Meerburg, P.D. Meinhold, P.R. Melchiorri, A. Mennella, A. Migliaccio, M. Miville-Deschênes, M.-A. Molinari, D. Moneti, A. Montier, L. Morgante, G. Moss, A. Münchmeyer, M. Natoli, P. Oppizzi, F. Pagano, L. Paoletti, D. Partridge, B. Patanchon, G. Perrotta, F. Pettorino, V. Piacentini, F. Polenta, G. Puget, J.-L. Rachen, J.P. Racine, B. Reinecke, M. Remazeilles, M. Renzi, A. Rocha, G. Rubiño-Martín, J.A. Ruiz-Granados, B. Salvati, L. Savelainen, M. Scott, D. Shellard, E.P.S. Shiraishi, M. Sirignano, C. Sirri, G. Smith, K. Spencer, L.D. Stanco, L. Sunyaev, R. Suur-Uski, A.-S. Tauber, J.A. AIM CEA CNRS Université Paris-Saclay Université Paris-Diderot Sorbonne Paris Cité Gif-sur-YvetteF-91191 France APC AstroParticule et Cosmologie Université Paris Diderot CNRS/IN2P3 CEA/lrfu Observatoire de Paris Sorbonne Paris Cité 10 rue Alice Domon et Léonie Duquet Paris Cedex 1375205 France African Institute for Mathematical Sciences 6-8 Melrose Road Muizenberg Cape Town South Africa Astrophysics Group Cavendish Laboratory University of Cambridge J J Thomson Avenue CambridgeCB3 0HE United Kingdom Astrophysics & Cosmology Research Unit School of Mathematics Statistics & Computer Science University of KwaZulu-Natal Westville Campus Private Bag X54001 Durban4000 South Africa CITA University of Toronto 60 St. George St. TorontoONM5S 3H8 Canada CNRS IRAP 9 Av. colonel Roche BP 44346 Toulouse Cedex 4F-31028 France California Institute of Technology PasadenaCA United States Centre for Theoretical Cosmology DAMTP University of Cambridge Wilberforce Road CambridgeCB3 0WA United Kingdom Computational Cosmology Center Lawrence Berkeley National Laboratory BerkeleyCA United States Département de Physique Théorique Université de Genève 24 Quai E. Ansermet Genève 41211 Switzerland Département de Physique École Normale Supérieure PSL Research University CNRS 24 rue Lhomond Paris75005 France La Laguna TenerifeE-38206 Spain Departamento de Física Universidad de Oviedo C/ Federico García Lorca 18 Oviedo Spain Department of Astrophysics IMAPP Radboud University P.O. Box 9010 Nijmegen6500 GL Netherlands Department of General Education National Institute of Technology Kagawa College 355 Chokushi-cho Takamatsu Kagawa761-8058 Japan Department of Mathematics University of Stellenbosch Stellenbosch7602 South Africa Department of Physics & Astronomy University of British Columbia 6224 Agricultural Road VancouverBC Canada Department of Physics & Astronomy University of the Western Cape Cape Town7535 South Africa Department of Ph

We analyse the Planck full-mission cosmic microwave background (CMB) temperature and E-mode polarization maps to obtain constraints on primordial non-Gaussianity (NG). We compare estimates obtained from separable template-fitting, binned, and optimal modal bispectrum estimators, finding consistent values for the local, equilateral, and orthogonal bispectrum amplitudes. Our combined temperature and polarization analysis produces the following final results: fNLlocal = −0.9 ± 5.1;fNLequil = −26 ± 47;and fNLortho = −38 ± 24 (68 % CL, statistical). These results include the low-multipole (4 ≤ ` localNL = (−5.8 ± 6.5) × 104 (68 % CL, statistical), while constraints for other trispectrum shapes are also determined. Exploiting the tight limits on various bispectrum and trispectrum shapes, we constrain the parameter space of different early-Universe scenarios that generate primordial NG, including general single-field models of inflation, multi-field models (e.g., curvaton models), models of inflation with axion fields producing parity-violation bispectra in the tensor sector, and inflationary models involving vector-like fields with directionally-dependent bispectra. Our results provide a high-precision test for structure-formation scenarios, showing complete agreement with the basic picture of the ΛCDM cosmology regarding the statistics of the initial conditions, with cosmic structures arising from adiabatic, passive, Gaussian, and primordial seed perturbations. Copyright © 2019, The Authors. All rights reserved.

关键词： Polarization

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Planck 2018 results. V. CMB power spectra and likelihoods

arXiv

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arXiv 2019年

作者： Collaboration, Planck Aghanim, N. Akrami, Y. Ashdown, M. Aumont, J. Baccigalupi, C. Ballardini, M. Banday, A.J. Barreiro, R.B. Bartolo, N. Basak, S. Benabed, K. Bernard, J.-P. Bersanelli, M. Bielewicz, P. Bock, J.J. Bond, J.R. Borrill, J. Bouchet, F.R. Boulanger, F. Bucher, M. Burigana, C. Butler, R.C. Calabrese, E. Cardoso, J.-F. Carron, J. Casaponsa, B. Challinor, A. Chiang, H.C. Colombo, L.P.L. Combet, C. Crill, B.P. Cuttaia, F. De Bernardis, P. De Rosa, A. De Zotti, G. Delabrouille, J. Delouis, J.-M. Di Valentino, E. Diego, J.M. Doré, O. Douspis, M. Ducout, A. Dupac, X. Dusini, S. Efstathiou, G. Elsner, F. Enßlin, T.A. Eriksen, H.K. Fantaye, Y. Fernandez-Cobos, R. Finelli, F. Frailis, M. Fraisse, A.A. Franceschi, E. Frolov, A. Galeotta, S. Galli, S. Ganga, K. Génova-Santos, R.T. Gerbino, M. Ghosh, T. Giraud-Héraud, Y. González-Nuevo, J. Górski, K.M. Gratton, S. Gruppuso, A. Gudmundsson, J.E. Hamann, J. Handley, W. Hansen, F.K. Herranz, D. Hivon, E. Huang, Z. Jaffe, A.H. Jones, W.C. Keihänen, E. Keskitalo, R. Kiiveri, K. Kim, J. Kisner, T.S. Krachmalnicoff, N. Kunz, M. Kurki-Suonio, H. Lagache, G. Lamarre, J.-M. Lasenby, A. Lattanzi, M. Lawrence, C.R. Le Jeune, M. Levrier, F. Lewis, A. Liguori, M. Lilje, P.B. Lilley, M. Lindholm, V. López-Caniego, M. Lubin, P.M. Ma, Y.-Z. Macías-Pérez, J.F. Maggio, G. Maino, D. Mandolesi, N. Mangilli, A. Marcos-Caballero, A. Maris, M. Martin, P.G. Martínez-González, E. Matarrese, S. Mauri, N. McEwen, J.D. Meinhold, P.R. Melchiorri, A. Mennella, A. Migliaccio, M. Millea, M. Miville-Deschênes, M.-A. Molinari, D. Moneti, A. Montier, L. Morgante, G. Moss, A. Natoli, P. Nørgaard-Nielsen, H.U. Pagano, L. Paoletti, D. Partridge, B. Patanchon, G. Peiris, H.V. Perrotta, F. Pettorino, V. Piacentini, F. Polenta, G. Puget, J.-L. Rachen, J.P. Reinecke, M. Remazeilles, M. Renzi, A. Rocha, G. Rosset, C. Roudier, G. Rubiño-Martín, J.A. Ruiz-Granados, B. Salvati, L. AIM CEA CNRS Université Paris-Saclay Université Paris-Diderot Sorbonne Paris Cité Gif-sur-YvetteF-91191 France APC AstroParticule et Cosmologie Université Paris Diderot CNRS/IN2P3 CEA/lrfu Observatoire de Paris Sorbonne Paris Cité 10 rue Alice Domon et Léonie Duquet Paris Cedex 1375205 France African Institute for Mathematical Sciences 6-8 Melrose Road Muizenberg Cape Town South Africa Aix Marseille Univ CNRS CNES LAM Marseille France Astrophysics Group Cavendish Laboratory University of Cambridge J J Thomson Avenue CambridgeCB3 0HE United Kingdom Astrophysics & Cosmology Research Unit School of Mathematics Statistics & Computer Science University of KwaZulu-Natal Westville Campus Private Bag X54001 Durban4000 South Africa CITA University of Toronto 60 St. George St. TorontoONM5S 3H8 Canada CNRS IRAP 9 Av. colonel Roche BP 44346 Toulouse Cedex 4F-31028 France Cahill Center for Astronomy and Astrophysics California Institute of Technology PasadenaCA91125 United States California Institute of Technology PasadenaCA United States Centre for Theoretical Cosmology DAMTP University of Cambridge Wilberforce Road CambridgeCB3 0WA United Kingdom Computational Cosmology Center Lawrence Berkeley National Laboratory BerkeleyCA United States DTU Space National Space Institute Technical University of Denmark Elektrovej 327 Kgs. LyngbyDK-2800 Denmark Département de Physique Théorique Université de Genève 24 Quai E. Ansermet Genève 41211 Switzerland Département de Physique École normale supérieure PSL Research University CNRS 24 rue Lhomond Paris75005 France La Laguna TenerifeE-38206 Spain Departamento de Física Universidad de Oviedo C/ Federico García Lorca 18 Oviedo Spain Department of Astrophysics IMAPP Radboud University P.O. Box 9010 Nijmegen6500 GL Netherlands Department of Mathematics University of Stellenbosch Stellenbosch7602 South Africa Department of Physics & Astronomy University of British Columbia 6224 Ag

We describe the legacy Planck cosmic microwave background (CMB) likelihoods derived from the 2018 data release. The overall approach is similar in spirit to the one retained for the 2013 and 2015 data release, with a hybrid method using different approximations at low (` MC, ωc, ωb, and H0 by more than 30 %, and ns by more than 20 % compared to TT-only constraints. Extensive tests on the robustness of the modelling of the polarization data demonstrate good consistency, with some residual modelling uncertainties. At high multipoles we are now limited mainly by the accuracy of the polarization efficiency modelling. Using our various tests, simulations, and comparison between different high-multipole likelihood implementations, we estimate the consistency of the results to be better than the 0.5 σ level on the ΛCDM parameters, as well as classical single-parameter extensions for the joint likelihood (to be compared to the 0.3 σ levels we achieved in 2015 for the temperature data alone on ΛCDM only). Minor curiosities already present in the previous releases remain, such as the differences between the best-fit ΛCDM parameters for the ` 800 ranges of the power spectrum, or the preference for more smoothing of the power-spectrum peaks than predicted in ΛCDM fits. These are shown to be driven by the temperature power spectrum and are not significantly modified by the inclusion of the polarization data. Overall, the legacy Planck CMB likelihoods provide a robust tool for constraining the cosmological model and represent a reference for future CMB observations. Copyright © 2019, The Authors. All rights reserved.

关键词： Cosmology

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Planck 2018 results. VII. Isotropy and statistics of the CMB

arXiv

引用

arXiv 2019年

作者： Akrami, Y. Ashdown, M. Aumont, J. Baccigalupi, C. Ballardini, M. Banday, A.J. Barreiro, R.B. Bartolo, N. Basak, S. Benabed, K. Bersanelli, M. Bielewicz, P. Bock, J.J. Bond, J.R. Borrill, J. Bouchet, F.R. Boulanger, F. Bucher, M. Burigana, C. Butler, R.C. Calabrese, E. Cardoso, J.-F. Casaponsa, B. Chiang, H.C. Colombo, L.P.L. Combet, C. Contreras, D. Crill, B.P. de Bernardis, P. de Zotti, G. Delabrouille, J. Delouis, J.-M. Di Valentino, E. Diego, J.M. Doré, O. Douspis, M. Ducout, A. Dupac, X. Efstathiou, G. Elsner, F. Enßlin, T.A. Eriksen, H.K. Fantaye, Y. Fernandez-Cobos, R. Finelli, F. Frailis, M. Fraisse, A.A. Franceschi, E. Frolov, A. Galeotta, S. Galli, S. Ganga, K. Génova-Santos, R.T. Gerbino, M. Ghosh, T. González-Nuevo, J. Górski, K.M. Gruppuso, A. Gudmundsson, J.E. Hamann, J. Handley, W. Hansen, F.K. Herranz, D. Hivon, E. Huang, Z. Jaffe, A.H. Jones, W.C. Keihänen, E. Keskitalo, R. Kiiveri, K. Kim, J. Krachmalnicoff, N. Kunz, M. Kurki-Suonio, H. Lagache, G. Lamarre, J.-M. Lasenby, A. Lattanzi, M. Lawrence, C.R. LeJeune, M. Levrier, F. Liguori, M. Lilje, P.B. Lindholm, V. López-Caniego, M. Ma, Y.-Z. Macías-Pérez, J.F. Maggio, G. Maino, D. Mandolesi, N. Mangilli, A. Marcos-Caballero, A. Maris, M. Martin, P.G. Martínez-González, E. Matarrese, S. Mauri, N. McEwen, J.D. Meinhold, P.R. Mennella, A. Migliaccio, M. Miville-Deschênes, M.-A. Molinari, D. Moneti, A. Montier, L. Moss, A. Natoli, P. Pagano, L. Paoletti, D. Partridge, B. Perrotta, F. Pettorino, V. Piacentini, F. Polenta, G. Puget, J.-L. Rachen, J.P. Reinecke, M. Remazeilles, M. Renzi, A. Rocha, G. Rosset, C. Roudier, G. Rubiño-Martín, J.A. Ruiz-Granados, B. Salvati, L. Savelainen, M. Scott, D. Shellard, E.P.S. Sirignano, C. Sunyaev, R. Suur-Uski, A.-S. Tauber, J.A. Tavagnacco, D. Tenti, M. Toffolatti, L. Tomasi, M. Trombetti, T. Valenziano, L. Valiviita, J. van Tent, B. Vielva, P. Villa, F. Vittorio, N. Wandelt, B.D. Wehus, I.K. Zacchei, A. Zibin, J.P. Zonca, A. AIM CEA CNRS Université Paris-Saclay Université Paris-Diderot Sorbonne Paris Cité Gif-sur-YvetteF-91191 France APC AstroParticule et Cosmologie Université Paris Diderot CNRS/IN2P3 CEA/lrfu Observatoire de Paris Sorbonne Paris Cité 10 rue Alice Domon et Léonie Duquet Paris Cedex 1375205 France African Institute for Mathematical Sciences 6-8 Melrose Road Muizenberg Cape Town South Africa Aix Marseille Univ CNRS CNES LAM Marseille France Astrophysics Group Cavendish Laboratory University of Cambridge J J Thomson Avenue CambridgeCB3 0HE United Kingdom Astrophysics & Cosmology Research Unit School of Mathematics Statistics & Computer Science University of KwaZulu-Natal Westville Campus Private Bag X54001 Durban4000 South Africa CITA University of Toronto 60 St. George St. TorontoONM5S 3H8 Canada CNRS IRAP 9 Av. colonel Roche BP 44346 Toulouse Cedex 4F-31028 France Cahill Center for Astronomy and Astrophysics California Institute of Technology PasadenaCA91125 United States California Institute of Technology PasadenaCA United States Centre for Theoretical Cosmology DAMTP University of Cambridge Wilberforce Road CambridgeCB3 0WA United Kingdom Computational Cosmology Center Lawrence Berkeley National Laboratory BerkeleyCA United States Département de Physique Théorique Université de Genève 24 Quai E. Ansermet Genève 41211 Switzerland Département de Physique École Normale Supérieure PSL Research University CNRS 24 rue Lhomond Paris75005 France La Laguna TenerifeE-38206 Spain Departamento de Física Universidad de Oviedo C/ Federico García Lorca 18 Oviedo Spain Department of Astrophysics IMAPP Radboud University P.O. Box 9010 Nijmegen6500 GL Netherlands Department of Mathematics University of Stellenbosch Stellenbosch7602 South Africa Department of Physics & Astronomy University of British Columbia 6224 Agricultural Road VancouverBC Canada Department of Physics & Astronomy University of the Western Cape Cape Town

Analysis of the Planck 2018 data set indicates that the statistical properties of the cosmic microwave background (CMB) temperature anisotropies are in excellent agreement with previous studies using the 2013 and 2015 data releases. In particular, they are consistent with the Gaussian predictions of the ΛCDM cosmological model, yet also confirm the presence of several so-called "anomalies" on large angular scales. The novelty of the current study, however, lies in being a first attempt at a comprehensive analysis of the statistics of the polarization signal over all angular scales, using either maps of the Stokes parameters, Q and U, or the E-mode signal derived from these using a new methodology (which we describe in an appendix). Although remarkable progress has been made in reducing the systematic effects that contaminated the 2015 polarization maps on large angular scales, it is still the case that residual systematics (and our ability to simulate them) can limit some tests of non-Gaussianity and isotropy. However, a detailed set of null tests applied to the maps indicates that these issues do not dominate the analysis on intermediate and large angular scales (i.e., `. 400). In this regime, no unambiguous detections of cosmological non-Gaussianity, or of anomalies corresponding to those seen in temperature, are claimed. Notably, the stacking of CMB polarization signals centred on the positions of temperature hot and cold spots exhibits excellent agreement with the ΛCDM cosmological model, and also gives a clear indication of how Planck provides state-of-the-art measurements of CMB temperature and polarization on degree scales. Copyright © 2019, The Authors. All rights reserved.

关键词： Polarization

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Author Correction: A systems biology approach uncovers cell-specific gene regulatory effects of genetic associations in multiple sclerosis

引用

Nature communications 2019年第1期10卷 2956页

作者： Lohith Madireddy Kicheol Kim Xiaoming Jia Adam Santaniello Stacy J. Caillier Bruce A. C. Cree Roland Henry Stephen L. Hauser Jorge R. Oksenberg Sergio E. Baranzini Nikolaos A. Patsopoulos Philip De Jager Chris Cotsapas Matthew R. Lincoln David A. Hafler Steffan D. Bos Hanne F. Harbo Tone Berge Elisabeth G. Celius Ashley Beecham Jacob McCauley Margaret A. Pericak-Vance Till F. M. Andlauer Christiane Gasperi Bernhard Hemmer Lisa F. Barcellos Luisa Bernardinelli Filippo Martinelli-Boneschi David R. Booth Graeme J. Stewart Farren Briggs Jonathan Haines Manuel Comabella Giancarlo Comi Federica Esposito Sandra D’Alfonso Katrina Dedham Pierre Duquette Efthimios Dardiotis Bertrand Fontaine An Goris Bénédicte Dubois Pierre-Antoine Gourraud Georgios Hadjigeorgiou Clive Hawkins Seema Kalra Rogier Hintzen Dana Horakova Noriko Isobe Jun-ichi Kira Michael Khalil Ingrid Kockum Tomas Olsson Christina M. Lill Felix Luessi Frauke Zipp Roland Martin Annette Oturai Aarno Palotie Janna Saarela Adrian Ivinson Bruce V. Taylor Alastair Compston Stephen Sawcer Weill Institute for Neurosciences Department of Neurology University of California San Francisco San Francisco CA 94158 USA Bakar Institute for Computational Health Science. University of California San Francisco San Francisco CA 94158 USA Systems Biology and Computer Science Program Ann Romney Center for Neurological Diseases Department of Neurology and Division of Genetics Department of Medicine Brigham & Women’s Hospital Harvard Medical School Boston MA 02115 USA Broad Institute of Harvard University and Massachusetts Institute of Technology Cambridge MA 02142 USA Department of Neurology Center for Translational and Computational Neuroimmunology and Multiple Sclerosis Center Columbia University Medical Center New York NY 10032 USA Departments of Neurology Yale School of Medicine 300 George St New Haven CT 06511 USA Department of Genetics Yale School of Medicine 300 George St New Haven CT 06511 USA Institute of Clinical Medicine University of Oslo Oslo 0318 Norway Department of Neurology Oslo University Hospital Oslo 0424 Norway Department of Mechanical Electronics and Chemical Engineering Oslo Metropolitan University Oslo 0167 Norway Institute of Health and Society University of Oslo Oslo 0318 Norway John P. Hussman Institute for Human Genomics University of Miami Miller School of Medicine Miami FL 33136 USA Dr. John T. Macdonald Foundation Department of Human Genetics University of Miami Miller School of Medicine Miami FL 33136 USA Department of Neurology Klinikum rechts der Isar School of Medicine Technical University of Munich 81675 Munich Germany Munich Cluster for Systems Neurology (SyNergy) 81377 Munich Germany Division of Epidemiology School of Public HealthUniversity of California 324 Stanley Hall MC#3220 Berkeley CA 94720 USA Section of Biostatistics Neurophyisiology and Psychiatry Unit of medical and genomic statistics Universita of Pavia Pavia 27100 Italy Department of Biomedical Sciences for Health Univers

An amendment to this paper has been published and can be accessed via a link at the top of the paper.

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