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Drug-Target Interactions Prediction Based on Signed Heterogeneous Graph Neural Networks

Chinese Journal of Electronics 2024年第1期33卷 231-244页

作者： Ming CHEN Yajian JIANG Xiujuan LEI Yi PAN Chunyan JI Wei JIANG College of Information Science and Engineering Hunan Normal University School of Computer Science Shaanxi Normal University Faculty of Computer Science and Control Engineering Shenzhen Institute of Advanced TechnologyChinese Academy of Sciences Computer Science Department BNU-HKBU United International College

Drug-target interactions(DTIs) prediction plays an important role in the process of drug *** computational methods treat it as a binary prediction problem, determining whether there are connections between drugs and targets while ignoring relational types information. Considering the positive or negative effects of DTIs will facilitate the study on comprehensive mechanisms of multiple drugs on a common target, in this work, we model DTIs on signed heterogeneous networks, through categorizing interaction patterns of DTIs and additionally extracting interactions within drug pairs and target protein pairs. We propose signed heterogeneous graph neural networks(SHGNNs), further put forward an end-to-end framework for signed DTIs prediction, called SHGNN-DTI,which not only adapts to signed bipartite networks, but also could naturally incorporate auxiliary information from drug-drug interactions(DDIs) and protein-protein interactions(PPIs). For the framework, we solve the message passing and aggregation problem on signed DTI networks, and consider different training modes on the whole networks consisting of DTIs, DDIs and PPIs. Experiments are conducted on two datasets extracted from Drug Bank and related databases, under different settings of initial inputs, embedding dimensions and training modes. The prediction results show excellent performance in terms of metric indicators, and the feasibility is further verified by the case study with two drugs on breast cancer.

关键词： Drug-target interactions Signed heterogeneous network Link sign prediction Graph neural networks

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A Review on Role of IoT and Machine Learning in Agriculture 7

A Review on Role of IoT and Machine Learning in Agriculture

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7th International Conference on Inventive Computation Technologies, ICICT 2024

作者： Kumar, Gulshan Choudhary, Vishal Kumar Kumar, Shravan Kumar, Rajan Kumar, Mukesh Gourshettiwar, Palash M. Faculty of Engineering And Technology Department of Computer Science And Design Maharashtra Wardha India Faculty of Engineering And Technology Department of Computer Science And Medical Engineering Maharashtra Wardha India

ISBN: (纸本)9798350359299

The agricultural area has undergone a significant transformation owing to the progress made in IoT. It is imperative to have a dependable remote monitoring solution right now. This study aims to accomplish two goals. First, a solution based on an app is offered, which effectively assists in remotely administering the field by displaying the current sensor values. In an Internet of Things based prototype surveillance system, a multi-class categorization method utilizing machine learning and deep learning is incorporated to classify labels such as clear farm, cow, horse, wild boar, and wild elephant. The analysis involved Support Vector Machines and Convolutional Neural Networks, with the accuracy measure being employed to determine the optimal model. The advancements in the Internet of Things (IoT) have significantly transformed the daily lives of individuals. A comprehensive understanding of soil properties gives a variety of soil-related information that can be used to improve crop yields. Machine learning is a cutting-edge technology that aids with agricultural precision and provides answers to crop yield issues. Significant informative advances and Machine Learning (ML) open up new opportunities for deciphering, quantifying, and comprehending data-intensive prediction in agricultural settings. This study thoroughly examines a number of machine learning topics for Internet of Things-based smart agriculture systems. © 2024 IEEE.

关键词： Support vector machines

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A Comprehensive Review on Data Visualization Techniques for Real-Time Information 7

A Comprehensive Review on Data Visualization Techniques for ...

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7th International Conference on Inventive Computation Technologies, ICICT 2024

作者： Choudhary, Vishal Kumar Kumar, Gulshan Suman, Saurabh Kumar, Abhishek Faculty of Engineering And Technology Department of Computer Science And Medical Engineering Maharashtra Wardha India Faculty of Engineering And Technology Department of Computer Science And Design Maharashtra Wardha India

ISBN: (纸本)9798350359299

Research on real-time data visualization methods is necessary to achieve the most accurate and clear representation of information. Creating specific boards and modifying current platforms are two key tasks in performing an appropriate information visualization. An overview of the studies on dashboard platforms, data visualization methods, and accessible strategies is given in this article. To evaluate the effects of the various data visualization approaches on the finished dashboard, a generic and dynamic dashboard based on real-time data was created. Consequently, a preliminary collection of cues, charts, tables, and reports will allow users to interact with the data. produced by the Dashboard itself. Making informed decisions across a variety of businesses requires the capacity to acquire and comprehend real-time information in today's data-driven environment. Real-time data visualization techniques are now essential for turning complex data into insights that can be put to use. This study examines the value of real-time data visualization and offers a summary of strategies and equipment that enable businesses to efficiently use real-time data. © 2024 IEEE.

关键词： Data visualization

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Optimizing Stand-Alone PV Systems:A Metaheuristic-Enhanced Fuzzy Approach for Adaptive MPPT

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China Communications 2025年第1期22卷 61-74页

作者： Tina Samavat Mostafa Nazari Lin Fuhong Lei Yang Department of Computer Science and Engineering University of NevadaRenoNVUSA Faculty of Mechanical Engineering Shahrood University of TechnologyShahroodIran School of Computer and Communication Engineering University of Science and Technology BeijingBeijing 100083China

This paper introduces a simple yet effective approach for developing fuzzy logic controllers(FLCs)to identify the maximum power point(MPP)and optimize the photovoltaic(PV)system to extract the maximum power in different environmental *** propose a robust FLC with low computational complexity by reducing the number of membership functions and *** optimize the performance of the FLC,metaheuristic algorithms are employed to determine the parameters of the *** evaluate the proposed FLC in various panel configurations under different environmental *** results indicate that the proposed FLC can easily adapt to various panel configurations and perform better than other benchmarks in terms of enhanced stability,responsiveness,and power transfer under various scenarios.

关键词： genetic algorithm imperialist competitive algorithm invasive weed algorithm maximum power point tracking

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Hybrid millimeter wave heterogeneous networks with spatially correlated user equipment

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Digital Communications and Networks 2024年第4期10卷 904-917页

作者： Arif Ullah Ziaul Haq Abbas Ghulam Abbas Fazal Muhammad Jae-Mo Kang Department of Computer Engineering College of IT ConvergenceChosun UniversityGwangju61452South Korea Faculty of Electrical Engineering GIK Institute of Engineering Sciences and TechnologyTopi23640Pakistan Faculty of Computer Science and Engineering GIK Institute of Engineering Sciences and TechnologyTopi23640Pakistan Department of Electrical Engineering University of Engineering and TechnologyMardan23200Pakistan Department of Artificial Intelligence Kyungpook National UniversityDaegu41566South Korea

In this paper,we analyze a hybrid Heterogeneous Cellular Network(HCNet)framework by deploying millimeter Wave(mmWave)small cells with coexisting traditional sub-6GHz macro cells to achieve improved coverage and high data *** consider randomly-deployed macro base stations throughout the network whereas mmWave Small Base Stations(SBSs)are deployed in the areas with high User Equipment(UE)*** user centric deployment of mmWave SBSs inevitably incurs correlation between UE and *** a realistic scenario where the UEs are distributed according to Poisson cluster process and directional beamforming with line-of-sight and non-line-of-sight transmissions is adopted for mmWave *** using tools from stochastic geometry,we develop an analytical framework to analyze various performance metrics in the downlink hybrid HCNets under biased received power *** UE clustering we considered Thomas cluster process and derive expressions for the association probability,coverage probability,area spectral efficiency,and energy *** also provide Monte Carlo simulation results to validate the accuracy of the derived ***,we analyze the impact of mmWave operating frequency,antenna gain,small cell biasing,and BSs density to get useful engineering insights into the performance of hybrid mmWave *** results show that network performance is significantly improved by deploying millimeter wave SBS instead of microwave BS in hot spots.

关键词： Downlink cell association Heterogeneous cellular networks Integrated sub-6GHz and mmWave networks Millimeter wave communications Poisson cluster process

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A Package Level Regression Test Selection Approach for Java Software Systems

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IEEE Access 2025年 13卷 87848-87861页

作者： Al-Refai, Mohammed Hammad, Mahmoud M. Jordan University of Science and Technology Faculty of Computer and Information Technology Computer Science Department Irbid22110 Jordan Faculty of Engineering and Information Technology Ajman United Arab Emirates Jordan University of Science and Technology Faculty of Computer and Information Technology Software Engineering Department Irbid22110 Jordan

Regression testing of software systems is an important and critical activity yet expensive and resource-intensive. An approach to enhance its efficiency is Regression Test Selection (RTS), which selectively re-executes a subset of relevant tests that are impacted by code modifications. Previous studies on static and dynamic RTS for Java software have shown that selecting tests at the class level is more effective than using finer granularities like methods or statements. Nevertheless, RTS at the package level, which is a coarser granularity than class level, has not been thoroughly investigated or evaluated for Java projects. To address this gap, we propose PKRTS, a static package-level RTS approach that utilizes the structural dependencies of the software system under test to construct a package-level dependency graph. PKRTS analyzes dependencies in the graph and identifies relevant tests that can reach modified packages, i.e., packages containing altered classes. In contrast to conventional static RTS techniques, PKRTS implicitly considers dynamic dependencies, such as Java reflection and virtual method calls, among classes belonging to the same package by treating all those classes as a single cohesive node in the dependency graph. We evaluated PKRTS on 885 revisions of 9 open-source Java projects, with its performance compared to Ekstazi, a state-of-the-art dynamic class-level approach, and STARTS, a state-of-the-art static class-level approach. We used Ekstazi as the baseline to measure the safety and precision violations of PKRTS and STARTS. The results indicated that PKRTS outperformed static class-level RTS in terms of safety violation, which measures the extent to which relevant test cases are missed. PKRTS showed an average safety violation of 2.29% compared to 5.94% safety violation of STARTS. Despite this, PKRTS demonstrated lower precision violation and lower reduction in test suite size than class-level RTS, as it selects higher number of irrelevant te

关键词： Java programming language

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IRS-enabled NOMA communication systems:A network architecture primer with future trends and challenges

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Digital Communications and Networks 2024年第5期10卷 1503-1528页

作者： Haleema Sadia Ahmad Kamal Hassan Ziaul Haq Abbas Ghulam Abbas Muhammad Waqas Zhu Han Faculty of Electrical Engineering and Telecommunications and Networking(TeleCoN)Research Center Ghulam Ishaq Khan Institute of Engineering and Technology(GIKI)Topi 23640Pakistan Faculty of Computer Science and Engineering GIKITopi 23640Pakistan Department of Computer Engineering College of Information TechnologyUniversity of Bahrain32028Bahrain School of Engineering Edith Cowan UniversityPerth WA6027Australia Department of Electrical and Computer Engineering University of HoustonHoustonTX 77004USA Department of Computer Science and Engineering Kyung Hee UniversitySeoul 446-701South Korea

Non-Orthogonal Multiple Access(NOMA)has already proven to be an effective multiple access scheme for5th Generation(5G)wireless *** provides improved performance in terms of system throughput,spectral efficiency,fairness,and energy efficiency(EE).However,in conventional NOMA networks,performance degradation still exists because of the stochastic behavior of wireless *** combat this challenge,the concept of Intelligent Reflecting Surface(IRS)has risen to prominence as a low-cost intelligent solution for Beyond 5G(B5G)*** this paper,a modeling primer based on the integration of these two cutting-edge technologies,i.e.,IRS and NOMA,for B5G wireless networks is *** in-depth comparative analysis of IRS-assisted Power Domain(PD)-NOMA networks is provided through 3-fold ***,a primer is presented on the system architecture of IRS-enabled multiple-configuration PD-NOMA systems,and parallels are drawn with conventional network configurations,i.e.,conventional NOMA,Orthogonal Multiple Access(OMA),and IRS-assisted OMA *** by this,a comparative analysis of these network configurations is showcased in terms of significant performance metrics,namely,individual users'achievable rate,sum rate,ergodic rate,EE,and outage ***,for multi-antenna IRS-enabled NOMA networks,we exploit the active Beamforming(BF)technique by employing a greedy algorithm using a state-of-the-art branch-reduceand-bound(BRB)*** optimality of the BRB algorithm is presented by comparing it with benchmark BF techniques,i.e.,minimum-mean-square-error,zero-forcing-BF,and ***,we present an outlook on future envisioned NOMA networks,aided by IRSs,i.e.,with a variety of potential applications for 6G wireless *** work presents a generic performance assessment toolkit for wireless networks,focusing on IRS-assisted NOMA *** comparative analysis provides a solid foundation for the dev

关键词： Intelligent reflecting surface Non-orthogonal multiple access 6G Beamforming Sum rate Energy efficiency

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Individualized Data Generation in Personalized Federated Learning

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IEEE Transactions on Mobile Computing 2025年第7期24卷 6628-6642页

作者： Cai, Yunyun Xi, Wei Shen, Yuhao Sun, Cerui Wang, Shuai Gong, Wei Zhao, Jizhong Xi'an Jiaotong University Faculty of Electronic and Information Engineering Xi'an China Southeast University School of Computer Science and Engineering Nanjing China University of Science and Technology of China School of Computer science and Technology Hefei China

Most Personalized Federated Learning (PFL) algorithms merge the model parameters of each client with other (similar or generic) model parameters to optimize the personalized model (PM). However, the merged model parameters in these algorithms may fit low relevance data, thereby limiting the performance of PM. In this paper, we generate similar data for each client through the collaboration of a generic model (GM) on the server, rather than merging model parameters. To train a generator capable of generating data for all classes on the server without real data, we employ the GM as the discriminator in adversarial training with the generator. Additionally, we introduce a similarity assessment metric, which allows for the assessment of the similarity between local data and data from other classes. Nevertheless, the presence of non-IID data among clients can weaken the performance of the GM, consequently impacting the training of the generator and similarity assessment. To address this issue, we design a directive mechanism so that GM can be optimized during adversarial training without the need for additional training. The experimental results validate the superiority of our algorithm over state-of-the-art algorithms in terms of accuracy, loss, and convergence speed. © 2002-2012 IEEE.

关键词： Federated learning

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Security to text (S2T): multi-layered based security approaches for secret text content

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Multimedia Tools and Applications 2025年第15期84卷 15151-15171页

作者： Kashid, Shamal Awasthi, Lalit K. Berwal, Krishan Department of Computer Science and Engineering National Institute of Technology Uttarakhand IN Srinagar India Faculty of Communication Engineering Military College of Telecommunication Engineering IN Mhow India

In the digital world, text data is produced in an unstructured manner across various communication channels. Extracting valuable information from such data with security is crucial and requires the development of techniques in text mining, information retrieval, and natural language processing (NLP). To solve this issue, we introduce two novel approaches: keyword extraction (KE) and a multi-layered secret sharing scheme (MLSS) to provide security to extracted keywords rather than overall text documents. The KE approach encompasses a sequence of text pre-processing procedures, including tokenization, stopword removal, stemming, and bag of words representation, followed by indexing. This methodology aims to efficiently extract keywords from text datasets. For this research work, we have proposed three datasets, including text messages, whatsapp messages, and electronic mail. MLSS enhances the security of extracted textual data by leveraging text pre-processing steps. This scheme ensures better confidentiality and the non-revealment of sensitive information. Additionally, we evaluate our KE model on our dataset as well as on standard datasets. Experimental results demonstrate the effectiveness of our proposed security to text (S2T) model, which outperform existing state-of-the-art approaches. The model obtains a 100% correlation between the reconstructed text and the original text. © The Author(s), under exclusive licence to Springer science+Business Media, LLC, part of Springer Nature 2024.

关键词： Extraction

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Application of AI and ML in Wound Healing and Skin Regeneration 4

Application of AI and ML in Wound Healing and Skin Regenerat...

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4th International Conference on Sentiment Analysis and Deep Learning, ICSADL 2025

作者： Petkar, Taniya G. Kumar, Praveen Sarate, Kirtiksha U. Faculty of Engineering and Technology Department of Computer Science & Medical Engineering Maharashtra Sawangi Wardha442001 India Faculty of Engineering and Technology Department of Computer Science and Design Maharashtra Sawangi Wardha442001 India

ISBN: (纸本)9798331523923

By enabling precise, individualized, and effective treatments, the integration of artificial intelligence (AI) and machine learning (ML) into wound and skin healing is revolutionizing healthcare. Artificial intelligence-controlled tools improve wound assessment, anticipate healing, and collaborate with regular examinations using cutting-edge dressings and imaging technologies. AI computations work on the management of express data to enhance treatment systems, while advancements in nanomaterials like marine collagen and therapies employing young microorganisms further accelerate skin recovery. Despite encouraging findings, there are still problems, such as potential overfitting and dataset limitations. In general, machine learning is changing the way that injuries are treated by providing proactive, tailored solutions that aim to understand outcomes and lower the cost associated with clinical outcomes. © 2025 IEEE.

关键词： Personalized medicine

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