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Application of 3D Printing and Design in Healthcare: A Focus on Undergraduate Research to Attract Students to Bioengineering and Related Disciplines 54

Application of 3D Printing and Design in Healthcare: A Focus...

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54th IEEE Frontiers in Education Conference, FIE 2024

作者： Zelada-Quiroz, Cindy M. Reyes-Santiago, Brian L. Ortiz-Rivera, Eduardo I. University of Puerto Rico at Mayagüez Bio-Engineering Graduate Program Mayagüez Puerto Rico University of Puerto Rico at Mayagüez Department of Computer Science and Engineering Mayagüez Puerto Rico University of Puerto Rico at Mayagüez Department of Electrical and Computer Engineering Mayagüez Puerto Rico

ISBN: (纸本)9798350351507

This research-to-practice paper describes developing and analyzing state-of-the-art smart boots created by combining CAD technology and advanced 3D printing techniques to attract students in bio-engineering and related fields. The primary objective of this innovative immobilization boot is to expedite fracture recovery phases through an ergonomic design to ensure optimal patient comfort during its use. Technological solutions are crucial in aiding the rehabilitation process for fractures caused by falls, heavy lifting, or rotational trauma. However, cost and comfort-related issues persist, underscoring the need for alternative approaches. This research addresses these challenges and delves into the broader implications of fracture treatment, catalyzing future projects and investigations in bioengineering. Additionally, this study serves as an educational tool that sparks the interest of high school and engineering students, promoting multidisciplinary collaboration in innovation. By involving students in specialized courses covering 3D design, human bone anatomy, biology, and materials science, this initiative empowers them to deepen their knowledge and develop new technologies to address bone injury problems. Material analyses include evaluating the type of material depending on the fracture site, such as PLA for printing and cotton and silicone gel for the midsection between the splint and the body. This research aims to advance our understanding of the type of fracture, the methods associated with their treatment, and tissue repair processes during bone callus formation. To summarize, this multidisciplinary approach drives advancements in bio-engineering and related fields, aiming to enhance patient outcomes and inspire students to pursue further research in bio-engineering and related fields. As part of this endeavor, a list of university-level courses based on the experience of the University of Puerto Rico at Mayaguez (UPRM), such as biology, bio-materials, 3D

关键词： Students

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Microservices Architecture As a Data Governance Tools in Decentralized E-Government

Microservices Architecture As a Data Governance Tools in Dec...

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2022 International Conference on science and Technology, ICOSTECH 2022

作者： Paramita, Adi Suryaputra Gaol, Ford Lomban Ranti, Benny Supangkat, Suhono Harso Graduate Program Universitas Ciputra Surabaya/ Bina Nusantara University Information Systems Department/Doctor of Computer Science Jakarta Surabaya Indonesia Bina Nusantara University Doctor of Computer Science Graduate Program Jakarta Indonesia Institute of Technology Bandung Systems and Information Technology Department Bandung Indonesia

ISBN: (纸本)9781665479851

Electronic government, or e-Government, is the use of information and communication technology by the public sector (ICT). Additionally, it can be viewed as a paradigm shift in terms of how governments operate. The government protects public values, while citizens act as problem solvers, co-creators, and active participants in value creation. On the other hand, decentralized systems have grown in popularity over the last few years. Data has become a significant issue in decentralized E-Government;each local entity has their own data, which is private. A suitable data governance tool is required to ensure that data governance is properly implemented and to prevent the organizational entity from leaking information. The purpose of this research is to examine the data governance tools mechanism utilizing microservices. © 2022 IEEE.

关键词： Information use

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A Systematic Literature Review of Deep Learning Application in Multiclass Anomaly Detection for Chest Medical Imaging

A Systematic Literature Review of Deep Learning Application ...

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International Conference of computer and Informatics Engineering (IC2IE)

作者： Philips Bens Pardamean Gregorius Natanael Elwirehardja Mahmud Isnan Computer Science Department BINUS Graduate Program - Master of Compuer Science Bina Nusantara University Jakarta Indonesia Bioinformatics and Data Science Research Center Bina Nusantara University Jakarta Indonesia

Medical imaging abnormality detection is challenging, but deep learning approaches have shown promise. This paper reviews the current state of the art in deep learning approaches for detecting abnormalities in chest medical imaging. To discover the trends, opportunities, and challenges associated with this field, 18 studies were selected from Google Scholar based on their titles, abstracts, and contents for extensive review to answer two research questions. The study found that the National Institutes of Health (NIH) Chest X-ray 14 dataset is the most used dataset for this task. Most research uses a single-modal approach, considering only image data as input, with X-ray being the more popular instrument. There are 8 out of 18 studies leverage the transfer learning approach, with ResN et50 being the most popular network. MobileNetV2 has demonstrated competitive results compared to more robust networks. Preprocessing techniques such as image enhancement and data augmentation are leveraged by 61.1 % of the reviewed studies and are shown to improve model performance.

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Conceptual design of polygenic risk score web portal 6

Conceptual design of polygenic risk score web portal

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6th International Conference on Information Management and Technology, ICIMTech 2021

作者： Rahutomo, Reza Budiarto, Arif Pardamean, Bens Bina Nusantara University School of Information Systems Information Systems Department Jakarta11480 Indonesia Bina Nusantara University School of Computer Science Computer Science Department Jakarta11480 Indonesia Bina Nusantara University BINUS Graduate Program - Master of Computer Science Computer Science Department Jakarta11480 Indonesia

ISBN: (纸本)9781665449373

The paradigm of polygenic risk score (PRS) has recently been getting much wider attention. PRS is a mathematical aggregate reflection of the risk conferred by deoxyribonucleic acid (DNA) variations to estimate the susceptibility of people to some certain onset of diseases. It is enumerated by summing risk alleles which are weighted by effect sizes in a large population derived from genome-wide association study (GWAS) where the gene variations are reproducible in different sets of GWAS. The emerging of direct-to-consumer genetics testing has tremendously increased access to genetics testing for broader users. The result of this genetics testing can be used as a disease predictive tool. One of the applications is PRS. PRS is a mathematical aggregate reflection of the risk conferred by DNA variations to estimate the susceptibility of people to some certain onset of diseases. However, the accessibility of these heavy statistics and mathematical models is limited to certain groups such as physicians and researchers. The objective of this study is to propose a conceptual design of web based PRS calculation available for public users. The users can maximize the utilization of their genotype data as a predictive tool for various disease risks. The design presented in this paper including the proposed class diagram, use case diagram, user journey diagram, and a series of user interface mock-ups. This result can be used as a prototype to gain users' feedback before implementing in production stage. © 2021 IEEE.

关键词： DNA

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Impact of CLAHE-based image enhancement for diabetic retinopathy classification through deep learning 7

Impact of CLAHE-based image enhancement for diabetic retinop...

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7th International Conference on computer science and Computational Intelligence, CSCI 2022

作者： Hayati, Mira Muchtar, Kahlil Roslidar Maulina, Novi Syamsuddin, Irfan Elwirehardja, Gregorius Natanael Pardamean, Bens Department of Electrical and Computer Engineering Universitas Syiah Kuala Banda Aceh23111 Indonesia Universitas Syiah Kuala Banda Aceh23111 Indonesia Faculty of Medicine Universitas Syiah Kuala Banda Aceh23111 Indonesia Department of Computer and Networking Engineering Politeknik Negeri Ujung Pandang Makassar90245 Indonesia Bioinformatics and Data Science Research Center Bina Nusantara University Jakarta 11480 Indonesia Computer Science Department BINUS Graduate Program-Master of Computer Science Program Bina Nusantara University Jakarta 11480 Indonesia

Diabetic retinopathy (DR) is a type of diabetes mellitus that attacks the retina of the eye. DR will cause patients to experience blindness slowly. Generally, DR can be detected by using a special instrument called an ophthalmoscope to view the inside of the eyeball. However, in conditions where there is a very small difference between the normal image and the DR image, computer-based assistance is needed for maximizing image reading value. In this research, a method of image quality improvement will be carried out which will then be integrated with a classification algorithm based on deep learning. The results of image improvement using Contrast Limited Adaptive Histogram Equalization (CLAHE) shows that the average accuracy of the method on several models is very competitive, 91% for the VGG16 model, 95% for InceptionV3, and 97% for EfficientNet compared to the results original image which only has an accuracy of 87% for VGG16 model, 90% for InceptionV3 model, and 95% for EfficientNet. However, in ResNet34 better accuracy is obtained in the original image with an accuracy of 95% while in the CLAHE image the accuracy value is only 84%. The results of this comprehensive evaluation and recommendation of famous backbone networks can be useful in the computer-Aided diagnosis of diabetic retinopathy. © 2022 Elsevier B.V.. All rights reserved.

关键词： Image enhancement

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Material informatics-driven insights into brain cancer nanocarriers: A bibliometric comparison of PLGA vs. liposomes

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OpenNano 2025年 21卷

作者： Makalew, Brilly Andro Abrori, Syauqi Abdurrahman Computer Science Department School of Computer Science Bina Nusantara University Jakarta 11480 Indonesia Automotive & Robotics Program Computer Engineering Department BINUS ASO School of Engineering Bina Nusantara University Jakarta 11480 Indonesia

This study explores a comparative analysis of PLGA nanoparticles and liposomes as potential carriers for brain cancer drug delivery, with a special focus on how material informatics enhances their design, biocompatibility, and drug release profiles to improve treatment efficacy and contribute to sustainable health outcomes. The investigation employed a bibliometric analysis using Scopus and VOSviewer to uncover the role of material informatics in optimizing these nanocarriers. The analysis revealed that material informatics, particularly through the application of machine learning and molecular dynamics simulations, significantly optimizes the performance of both PLGA nanoparticles and liposomes. The results highlighted distinct strengths of each nanocarrier: PLGA nanoparticles excel in biodegradability, while liposomes offer superior drug encapsulation capabilities. However, material informatics techniques bridged these enhancing drug release kinetics, stability, and biocompatibility. These improvements are crucial for effective delivery across the blood-brain barrier, a major challenge in brain cancer treatment. The integration of computational modelling, machine learning, and high-throughput screening enabled by material informatics is shown to be a key factor in advancing the design and optimization of these nanocarriers. By leveraging these tools, researchers can develop more personalized and efficient drug delivery systems tailored to address the specific challenges of glioblastoma therapy, ultimately contributing to sustainable health outcomes © 2024 The Author(s)

关键词： Bibliometric analysis Brain cancer Drug delivery Liposomes Material informatics Nanocarriers PLGA nanoparticles VOSviewer

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The Evaluation of Trust Towards The Intention to Use of Blockchain-Based Crowdwork Systems (Case Study of Creative Industry) 8

The Evaluation of Trust Towards The Intention to Use of Bloc...

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8th International Conference on Information Management and Technology, ICIMTech 2023

作者： Hartono, Sugiarto Prabowo, Harjanto Meyliana Hidayanto, Achmad Nizar School of Information Systems Bina Nusantara University Information Systems Department Jakarta11480 Indonesia Binus Business School Undergraduate Program Bina Nusantara University Management Department Jakarta11480 Indonesia Universitas Indonesia Faculty of Computer Science Depok Indonesia

ISBN: (纸本)9798350326093

Current crowdwork research still has issues related to trust. Workers and employers do not know each other, so problems related to trust will arise. This trust issue will influence the desire to use the crowdwork system. This study will evaluate trust in the intention to use blockchain-based crowdwork systems in creative industries. The methodology used is a quantitative approach (questionnaire) which is distributed to 200 respondents consisting of workers and employers. After that, testing the inner and outer models was carried out. The results obtained are technology, risk, and reputation which have the greatest impact on trust. The use of blockchain technology can minimize risks when using a crowdwork system, such as data that cannot be changed, data tracing can be done, and so on. The rating and review features are also important to be able to find out the user's reputation in the system. © 2023 IEEE.

关键词： Blockchain

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Curriculum-based Reinforcement Learning for an Effective Multi-Agent Path Planning Algorithm in Warehouse Scenarios 15

Curriculum-based Reinforcement Learning for an Effective Mul...

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15th IEEE International Conference on Industry Applications, INDUSCON 2023

作者： de Oliveira, Iure Rosa L. de Carvalho, Kevin B. Brandão, Alexandre S. Graduate Program in Computer Science Universidade Federal de Viçosa Viçosa Brazil Electrical Engineering Department Universidade Federal de Viçosa Viçosa Brazil

ISBN: (纸本)9798350314182

Multi-robot systems can provide substantial increase in efficiency and/or flexibility in different scenarios. Applications in various settings have been studied in the literature, such as disaster management, surveillance, object transportation as well as search-and-rescue. A particular case that can highly benefit from the employment of multiple agents is the logistics in a warehouse scenario. This work proposes an multi-agent Q-learning based algorithm with curriculum learning and transfer learning to perform the path planning process. With progressively more complex stages of training as well as knowledge transfer from one stage to another, the algorithm is capable of achieve high success rates. In order to validate the proposed method, simulations were done to compare it to other combinations of the used techniques, as well as using Q-learning only. Scalability tests were also performed. The proposed method achieved up to 94% success rate after training. © 2023 IEEE.

关键词： Curriculum Learning Mobile Robotics Multi-Agent System Reinforcement Learning Transfer Learning

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Bridging Accuracy and Efficiency: The Role of PINNs in Immune Response Simulations

Bridging Accuracy and Efficiency: The Role of PINNs in Immun...

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2024 IEEE International Conference on Bioinformatics and Biomedicine, BIBM 2024

作者： Fernandes, Thiago E. Dos Santos, Rodrigo W. Lobosco, Marcelo Federal University of Juiz de Fora Graduate Program on Computational Modelling Juiz de Fora Brazil Federal University of Juiz de Fora Institute of Exact Sciences Department of Computer Science Juiz de Fora Brazil

ISBN: (纸本)9798350386226

Myocarditis, characterized by inflammation of the heart muscle, has seen a notable 62.2% increase in incidence over the past three decades, leading to 324,490 deaths in 2019. Despite advancements in understanding its etiology, several critical questions remain unresolved, highlighting the need for improved patient treatment strategies. Computational methods play a crucial role in unraveling the complex interactions between pathogens and the immune system. This study explores the use of Physics-Informed Neural Networks (PINNs) to accelerate a newly developed model for myocardial edema formation in acute infectious myocarditis. The model describes the concentrations of pathogens and leukocytes using a nonlinear system of ordinary differential equations (ODEs). Our findings demonstrate a mean computational speedup of 5.93, while maintaining a Root Mean Squared Error of 0.0015. These results indicate that PINNs can accurately replicate the ODE system's solutions, offering substantial computational efficiency for this application. © 2024 IEEE.

关键词： Pathogens

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Handling Problems of Credit Data for Imbalanced Classes using SMOTEXGBoost 3

Handling Problems of Credit Data for Imbalanced Classes usin...

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3rd International Conference on Computational science and Information Management, ICoCSIM 2019

作者： Mardiansyah, Heru Widia Sembiring, Rahmat Efendi, Syahril Graduate Program of Computer Science Department of Information Technology Department of Computer Science Faculty of Computer Science and Information Technology Universitas Sumatera Utara Medam Indonesia

Some researchers find data with imbalanced class conditions, where there are data with a number of minorities and a majority. SMOTE is a data approach for an imbalanced classes and XGBoost is one algorithm for an imbalanced data problems. This research uses SMOTE and XGBoost or abbreviated as SMOTEXGBoost for handling data with an imbalanced classes. The results showed almost the same accuracy value between SMOTE and SMOTEXGBoost at 99%. While the value of AUC SMOTEXBoost has a more stable value than SMOTE that is equal to 99.89% for training and 98.51% for testing. © Published under licence by IOP Publishing Ltd.

关键词： Data handling

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