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Epileptic Seizure Detection Using a Hybrid 1D CNN-Machine Learning Approach from EEG Data

Journal of Healthcare Engineering 2022年第1期2022卷 9579422页

作者： Hassan, Fatima Hussain, Syed Fawad Qaisar, Saeed Mian Faculty of Computer Science and Engineering G. I. K. Institute Topi Pakistan School of Computer Science University of Birmingham Birmingham United Kingdom Electrical and Computer Engineering Department Effat University Jeddah22332 Saudi Arabia Communication and Signal Processing Lab Energy and Technology Research Center Effat University Jeddah22332 Saudi Arabia

Electroencephalography (EEG) is a widely used technique for the detection of epileptic seizures. It can be recorded in a noninvasive manner to present the electrical activity of the brain. The visual inspection of nonlinear and highly complex EEG signals is both costly and time-consuming. Therefore, an effective automatic detection system is needed to assist in the long-term evaluation and treatment of patients. Traditional approaches based on machine learning require feature extraction, while deep learning approaches are time-consuming and require more layers for effective feature learning and processing of complex EEG waveforms. Deep learning-based approaches also have weak generalization ability. This paper proposes a solution based on the combination of convolution neural networks (CNN) and machine learning classifiers. It preprocesses the EEG signal using the Butterworth filter and performs feature extraction using CNN. From the extracted set of features, the approach selects only the relevant features using mutual information-based estimators to reduce the curse of dimensionality and improve classification accuracy. The selected features are then passed as input to different machine learning classifiers. The suggested solution is evaluated on the University of Bonn dataset and CHB-MIT datasets. Our model effectively predicts 2, 3, 4, and 5 classes with accuracy of 100%, 99%, 94.6%, and 94%, respectively, for the Bonn dataset and 98% for CHB-MIT datasets. © 2022 Fatima Hassan et al.

关键词： Electroencephalography

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AI-enabled CT-guided end-to-end quantification of total cardiac activity in 18FDG cardiac PET/CT for detection of cardiac sarcoidosis

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Journal of Nuclear Cardiology 2025年 48卷 102195页

作者： Miller, Robert JH. Shanbhag, Aakash Marcinkiewicz, Anna M. Struble, Helen Gransar, Heidi Hijazi, Waseem Fujito, Hidesato Kransdorf, Evan Kavanagh, Paul Liang, Joanna X. Builoff, Valerie Dey, Damini Berman, Daniel S. Slomka, Piotr J. Departments of Medicine (Division of Artificial Intelligence in Medicine) Imaging and Biomedical Sciences Cedars-Sinai Medical Center Los Angeles CA United States Department of Cardiac Sciences University of Calgary Calgary AB Canada Signal and Image Processing Institute Ming Hsieh Department of Electrical and Computer Engineering University of Southern California Los Angeles CA United States Center of Radiological Diagnostics National Medical Institute of the Ministry of the Interior and Administration Warsaw Poland

Background: [18F]-fluorodeoxyglucose ([18F]FDG) positron emission tomography (PET) plays a central role in diagnosing and managing cardiac sarcoidosis. We propose a fully automated pipeline for quantification of [18F]FDG PET activity using deep learning (DL) segmentation of cardiac chambers on computed tomography (CT) attenuation maps and evaluate quantitative approaches based on this framework. Methods: We included consecutive patients undergoing [18F]FDG PET/CT for suspected cardiac sarcoidosis. DL segmented left atrium, left ventricle (LV), right atrium, right ventricle, aorta, LV myocardium, and lungs from CT attenuation scans. CT-defined anatomical regions were applied to [18F]FDG PET images automatically to quantify target to background ratio (TBR), volume of inflammation (VOI) and cardiometabolic activity (CMA) using full sized and shrunk segmentations. Results: A total of 69 patients were included, with mean age of 56.1 ± 13.4 and cardiac sarcoidosis present in 29 (42 %). CMA had highest prediction performance (area under the receiver operating characteristic curve [AUC] .919, 95 % confidence interval [CI] .858 – .980) followed by VOI (AUC .903, 95 % CI .834 – .971), TBR (AUC .891, 95 % CI .819 – .964), and maximum standardized uptake value (AUC .812, 95 % CI .701 – .923). Abnormal CMA (≥1) had a sensitivity of 100 % and specificity 65 % for cardiac sarcoidosis. Lung quantification was able to identify patients with pulmonary abnormalities. Conclusion: We demonstrate that fully automated volumetric quantification of [18F]FDG PET for cardiac sarcoidosis based on CT attenuation map-derived volumetry is feasible, rapid, and has high prediction performance. This approach provides objective measurements of cardiac inflammation with consistent definition of myocardium and background region. © 2025 American Society of Nuclear Cardiology

关键词： Cardiac sarcoidosis Deep learning Hypermetabolism Positron emission tomography Quantification

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A Reliable Method to Estimate the Bispectral Index Value Using a Single Frontal EEG Channel for Intra and Inter Subject Variability

A Reliable Method to Estimate the Bispectral Index Value Usi...

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2023 IEEE International Symposium on Medical Measurements and Applications, MeMeA 2023

作者： Shahbakhti, Mohammad Beiramvand, Matin Krycinska, Roza Nasiri, Erfan Chen, Wei Sole-Casals, Jordi Wierzchon, Michal Broniec-Wojcik, Anna Augustyniak, Piotr Marozas, Vaidotas Biomedical Engineering Institute Kaunas University of Technology Kaunas Lithuania Tampere University Faculty of Information Technology and Communication Tempere Finland Jagiellonian University Medical College Doctoral School in Medical and Health Sciences Krakow Poland Jagiellonian University Collegium Medicum Department of Interdisciplinary Intensive Care Krakow Poland Allameh Tabataba'i University Faculty of Statistics Mathematics and Computer Tehran Iran Fudan University Center for Intelligent Medical Electronics School of Information Science and Technology Shanghai China University of Vic-Central University of Catalonia Data and Signal Processing Research Group Vic Spain Institute of Psychology Jagiellonian University Krakow Poland Agh University of Science and Technology Department of Biocybernetics and Biomedical Engineering Krakow Poland

ISBN: (纸本)9781665493840

Objective: Monitoring the depth of anesthesia (DoA) plays an important role for administering the drug injection during a surgery, i.e., preventing undesired awareness and inordinate anesthetic depth. Although the bispectral index (BIS) monitor is the golden standard system for the DoA monitoring, it is still not affordable for the developing countries. Alternatively, a low-cost electroencephalogram (EEG) headband can be used. The objective of this paper is to present a new algorithm for estimating the BIS values using a single frontal EEG channel. Method: In the first step, the EEG signal is filtered for the elimination of artifacts and is split into its sub-bands. In the second step, several linear and nonlinear features are extracted from each sub-band and fed to a random forest regression model in order to estimate the BIS. The performance of the proposed algorithm is assessed using EEG data recorded from twenty-four subjects during the general anesthesia and is validated in terms of correlation coefficient (CC) and absolute error (AE) between the reference and estimated BIS values. Results: The proposed algorithm achieved the mean CC of 0.83 and AE of 6.5 for intra subject variability and mean CC of 0.87 and AE of 5.5 for inter subject variability. Significance: Given the similar results for both intra and inter subject variability, the proposed algorithm has the potential to be used in the real-world scenario. © 2023 IEEE.

关键词： Electroencephalography

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SLIDE-BASED GRAPH COLLABORATIVE TRAINING FOR HISTOPATHOLOGY WHOLE SLIDE image ANALYSIS

arXiv

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arXiv 2024年

作者： Shi, Jun Shu, Tong Jiang, Zhiguo Wang, Wei Wu, Haibo Zheng, Yushan School of Software Hefei University of Technology Hefei230601 China School of Computer Science and Information Engineering Hefei University of Technology Hefei230601 China Image Processing Center School of Astronautics Beihang University Beijing102206 China Department of Pathology The First Affiliated Hospital of USTC University of Science and Technology of China Hefei230036 China School of Engineering Medicine Beijing Advanced Innovation Center on Biomedical Engineering Beihang University Beijing100191 China

The development of computational pathology lies in the consensus that pathological characteristics of tumors are significant guidance for cancer diagnostics. Most existing research focuses on the inner-contextual information within each WSI yet ignores the possible inter-correlations between slides. As the development of tumors is a continuous process involving a series of histological, morphological, and genetic changes that accumulate over time, the similarities and differences between WSIs across various stages, grades, locations and patients should potentially contribute to the representation of WSIs and deserve to be taken into account in WSI modeling. To verify the advancement of introducing the slide inter-correlations into the representation learning of WSIs, we proposed a generic WSI analysis pipeline SlideGCD that can be adapted to any existing Multiple Instance Learning (MIL) frameworks and improve their performance. With the new paradigm, the prior knowledge of cancer development can participate in the end-to-end workflow, which concurrently initializes and refines the slide representation, as a guide for message passing in the slide-based graph. Extensive comparisons and experiments are conducted to validate the effectiveness and robustness of the proposed pipeline across 4 different tasks, including cancer subtyping, cancer staging, survival prediction, and gene mutation prediction, with 7 representative SOTA WSI analysis frameworks as backbones. Copyright © 2024, The Authors. All rights reserved.

关键词： WSI circuits

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Construction of Ternary Bent Functions From Ternary Linear Functions

Construction of Ternary Bent Functions From Ternary Linear F...

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International Symposium on Multiple-Valued Logic

作者： Milena Stanković Radomir S. Stanković Claudio Moraga Jaakko T. Astola Faculty of Electronic Engineering Department of Computer ScienceNi&#x0161 Serbia Mathematical Institute of SASA Belgrade Serbia Faculty of Computer Science Technical University of Dortmund Dortmund Germany Department of Informatics Technical University &#x201C Federico Santa Mar&#x00ED a&#x201D Valpara&#x00ED so Chile Department of Signal Processing Tampere University of Technology Tampere Finland

ISBN: (数字)9781665423953

ISBN: (纸本)9781665423960

As in the binary case, ternary bent functions are defined as most non-linear ternary functions meaning that they are at the largest possible Hamming distance from affine ternary functions. It is therefore interesting to observe that some ternary bent functions can be constructed as various combinations of linear ternary functions. By starting from the combination of linear functions corresponding to the basic ternary bent functions the construction of different other ternary bent functions can be performed by the application of different combinations of FFT-like permutation matrices for ternary functions.

关键词： Hamming distance

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Real-Time Dynamic Data Driven Deformable Registration for image-Guided Neurosurgery: Computational Aspects

arXiv

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arXiv 2023年

作者： Chrisochoides, Nikos Fedorov, Andrey Liu, Yixun Kot, Andriy Foteinos, Panos Drakopoulos, Fotis Tsolakis, Christos Billias, Emmanuel Clatz, Olivier Ayache, Nicholas Golby, Alex Black, Peter Kikinis, Ron Center for Real-Time Computing Computer Science Department Old Dominion University NorfolkVA United States Inria French Research Institute for Digital Science Sophia Antipolis France Neuroimaging Analysis Center Department of Radiology Harvard Medical School BostonMA United States Image-guided Neurosurgery Department of Neurosurgery Harvard Medical School BostonMA United States

Current neurosurgical procedures utilize medical images of various modalities to enable the precise location of tumors and critical brain structures to plan accurate brain tumor resection. The difficulty of using preoperative images during the surgery is caused by the intraoperative deformation of the brain tissue (brain shift), which introduces discrepancies concerning the preoperative configuration. Intra-operative imaging allows tracking such deformations but cannot fully substitute for the quality of the pre-operative data. Dynamic Data Driven Deformable Non-Rigid Registration (D4NRR) is a complex and time-consuming image processing operation that allows the dynamic adjustment of the pre-operative image data to account for intra-operative brain shift during the surgery. This paper summarizes the computational aspects of a specific adaptive numerical approximation method and its variations for registering brain MRIs. It outlines its evolution over the last 15 years and identifies new directions for the computational aspects of the technique. © 2023, CC BY-SA.

关键词： Tumors

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ReactFace: Online Multiple Appropriate Facial Reaction Generation in Dyadic Interactions

arXiv

引用

arXiv 2023年

作者： Luo, Cheng Song, Siyang Xie, Weicheng Spitale, Micol Ge, Zongyuan Shen, Linlin Gunes, Hatice Computer Vision Institute College of Computer Science and Software Engineering Shenzhen University Shenzhen518060 China Guangdong Provincial Key Laboratory of Intelligent Information Processing Shenzhen University Shenzhen518060 China Department of Computer Science University of Nottingham Ningbo China Ningbo315100 China Computer Sciences University of Exeter ExeterEX4 4PY United Kingdom Department of Computer Science and Technology University of Cambridge CambridgeCB3 0FT United Kingdom Airdoc-Monash Research Centre Monash University Faculty of IT Monash University Melbourne Australia

In dyadic interaction, predicting the listener’s facial reactions is challenging as different reactions could be appropriate in response to the same speaker’s behaviour. Previous approaches predominantly treated this task as an interpolation or fitting problem, emphasizing deterministic outcomes but ignoring the diversity and uncertainty of human facial reactions. Furthermore, these methods often failed to model short-range and long-range dependencies within the interaction context, leading to issues in the synchrony and appropriateness of the generated facial reactions. To address these limitations, this paper reformulates the task as an extrapolation or prediction problem, and proposes an novel framework (called ReactFace) to generate multiple different but appropriate facial reactions from a speaker behaviour rather than merely replicating the corresponding listener facial behaviours. Our ReactFace generates multiple different but appropriate photo-realistic human facial reactions by: (i) learning an appropriate facial reaction distribution representing multiple different but appropriate facial reactions;and (ii) synchronizing the generated facial reactions with the speaker verbal and non-verbal behaviours at each time stamp, resulting in realistic 2D facial reaction sequences. Experimental results demonstrate the effectiveness of our approach in generating multiple diverse, synchronized, and appropriate facial reactions from each speaker’s behaviour. The quality of the generated facial reactions is intimately tied to the speaker’s speech and facial expressions, achieved through our novel speaker-listener interaction modules. Our code is made publicly available at https://***/lingjivoo/ReactFace. Copyright © 2023, The Authors. All rights reserved.

关键词： Extrapolation

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Taking a Deep Breath: Enhancing Language Modeling of Large Language Models with Sentinel Tokens

arXiv

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arXiv 2024年

作者： Luo, Weiyao Zheng, Suncong Xia, Heming Wang, Weikang Lei, Yan Liu, Tianyu Chen, Shuang Sui, Zhifang State Key Laboratory of Multimedia Information Processing School of Computer Science Peking University China School of Software & Microelectronics Peking University China Tencent MLPD China Department of Computing The Hong Kong Polytechnic University Hong Kong Institute of Computing Technology Chinese Academy of Sciences China Alibaba Group China

Large language models (LLMs) have shown promising efficacy across various tasks, becoming powerful tools in numerous aspects of human life. However, Transformer-based LLMs suffer a performance degradation when modeling long-term contexts due to they discard some information to reduce computational overhead. In this work, we propose a simple yet effective method to enable LLMs to take a deep breath, encouraging them to summarize information contained within discrete text chunks. Specifically, we segment the text into multiple chunks and insert special token at the end of each chunk. We then modify the attention mask to integrate the chunk's information into the corresponding token. This facilitates LLMs to interpret information not only from historical individual tokens but also from the token, aggregating the chunk's semantic information. Experiments on language modeling and out-of-domain downstream tasks validate the superiority of our approach. Copyright © 2024, The Authors. All rights reserved.

关键词： Semantics

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Asymmetry Total Variation and Framelet Regularized Nonconvex Low-Rank Tensor Completion

SSRN

引用

SSRN 2022年

作者： Chen, Yongyong Zhao, Xiaojia Xu, Tingting Zeng, Haijin Xu, Yanhui Chen, Junxing The School of Computer Science and Technology Harbin Institute of Technology Shenzhen518055 China Guangdong Provincial Key Laboratory of Novel Security Intelligence Technologies Shenzhen518055 China Image Processing and Interpretation Imec Research Group Ghent University Belgium Department of Electrical and Computer Engineering Faculty of Science and Technology University of Macau China The College of Medicine and Biological Information Engineering Northeastern University Shenyang110004 China

The low-rank tensor representation has shown enormous potential and advantages in diverse applications. However, (1) due to the inherent limitations of the low-rank tensor model, the tensor nuclear norm is utilized yet as a biased estimate of the tensor rank, which limits the image recovery performance. (2) most current low-rank approximation-based methods focus on the preservation of global information, while ignoring the local details preservation such as the spatial piece-wise smoothness and sharp edges. To overcome he above obstacles, we propose a novel asymmetry three-dimensional total variation and framelet regularized nonconvex low-rank tensor completion (ATV-FNTC) model, which integrates the nonconvex penalty function and asymmetric three-dimensional total variation into one unified model. Specifically, ATV-FNTC introduces one nonconvex penalty function as a tighter regularizer to approximate the tensor rank. Different from existing methods, the asymmetric three-dimensional total variation regularization is developed to achieve more accurate recovery of detailed information and flexibly control the smoothing strength of different dimensions of tensor data. Furthermore, we design an iterative algorithm to solve the nonconvex ATV-FNTC model by the alternating direction methods of multipliers. Experimental results reveal the superiority of the proposed method compared with several state-of-the-art methods when handling different completion tasks. © 2022, The Authors. All rights reserved.

关键词： Tensors

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Unsupervised representation learning from pathology images with multi-directional contrastive predictive coding

arXiv

引用

arXiv 2021年

作者： Carse, Jacob Carey, Frank McKenna, Stephen Computer Vision and Image Processing School of Science and Engineering University of Dundee Dundee United Kingdom Department of Pathology Ninewells Hospital Medical School Dundee United Kingdom

Digital pathology tasks have benefited greatly from modern deep learning algorithms. However, their need for large quantities of annotated data has been identified as a key challenge. This need for data can be countered by using unsupervised learning in situations where data are abundant but access to annotations is limited. Feature representations learned from unannotated data using contrastive predictive coding (CPC) have been shown to enable classifiers to obtain state of the art performance from relatively small amounts of annotated computer vision data. We present a modification to the CPC framework for use with digital pathology patches. This is achieved by introducing an alternative mask for building the latent context and using a multi-directional PixelCNN autoregressor. To demonstrate our proposed method we learn feature representations from the Patch Camelyon histology dataset. We show that our proposed modification can yield improved deep classification of histology *** Codes 68T45 (Primary) 68T07 (Secondary) Copyright © 2021, The Authors. All rights reserved.

关键词： Medical imaging

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