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1st Workshop on Environmental science, Society, and Technology, WESTECH 2018

作者： Abdullah, Dahlan Hartono, H. Saddhono, Kundharu Kurniasih, Nuning Iskandar, Akbar Rianita, Dian Purwarno Setyawasih, Rianti Satria, Erwinsyah Nuryanto, Tato Herawati, Lilik Sujinah Sudarsana, I Ketut Department of Informatics Universitas Malikussaleh Aceh Utara Indonesia Department of Computer Science STMIK IBBI Medan Indonesia Graduate Program Universitas Sebelas Maret Surakarta Indonesia Faculty of Communication Sciences Library and Information Science Program Universitas Padjadjaran Bandung Indonesia Department of Informatics STMIK AKBA Makassar Indonesia Department of Public Administrations Universitas Lancang Kuning Indonesia Faculty of Literature Universitas Islam Sumatera Utara Medan Indonesia Indonesia Department of Management Faculty of Economic Universitas Islam 45 Bekasi Indonesia Faculty of Teacher Training and Education Universitas Bung Hatta Padang Indonesia FITK IAIN Syekh Nurjati Cirebon Indonesia Department of Indonesian Language Teaching Institut Agama Islam Negeri Syekh Nurjati Cirebon Cirebon Indonesia Faculty of Education University Muhammadiyah of Surabaya Surabaya Indonesia Department of Religious Education Institut Hindu Dharma Negeri Denpasar Indonesia

Decision making is sometimes faced with a situation where assessment is given in the form of linguistic variables, which have a certain range of values so that decision making cannot be given in the form of numerical values. One approach commonly used is Hesitant Fuzzy Linguistic Term Sets (HFLTS) which is a multi-criteria and multi-alternative decision making method. In TOPSIS which has the concept of distance measurement, basically the chosen one is the best alternative is an alternative that has the closest distance to a positive solution and the farthest distance with a negative solution. The incorporation of HFLTS-TOPSIS has the advantage that decision making can be done in the form of variable linguistics and also a situation where there are benefit criteria and cost criteria. This study will use the HFLTS-TOPSIS approach that has been modified in the distance calculation section so that distance calculation is based on the difference of preference degree between the two HFLTS. The results of research conducted by a number of researchers show that using pseudo-distance will provide advantages compared to the standard HLFTS-TOPSIS. Pseudo-distance HFLTS-TOPSIS will be applied in the selection of the best lecturers. The criteria used in this study are: Student Satisfaction, Research, Number of late, and number of complaints from students. © Published under licence by IOP Publishing Ltd.

关键词： Decision making

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Mixture-of-experts variational autoencoder for clustering and generating from similarity-based representations

arXiv

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arXiv 2019年

作者： Kopf, Andreas Fortuin, Vincent Somnath, Vignesh Ram Claassen, Manfred Institute of Molecular Systems Biology Department of Biology ETH Zürich Switzerland Biomedical Informatics Group Department of Computer Science ETH Zürich Switzerland Switzerland Life Science Graduate School Zurich PhD Program Systems Biology Switzerland

Clustering high-dimensional data, such as images or biological measurements, is a long-standing problem and has been studied extensively. Recently, Deep Clustering gained popularity due to the non-linearity of neural networks, which allows for flexibility in fitting the specific peculiarities of complex data. Here we introduce the Mixture-of-Experts Similarity Variational Autoencoder (MoE-Sim-VAE), a novel generative clustering model. The model can learn multi-modal distributions of high-dimensional data and use these to generate realistic data with high efficacy and efficiency. MoE-Sim-VAE is based on a Variational Autoencoder (VAE), where the decoder consists of a Mixture-of-Experts (MoE) architecture. This specific architecture allows for various modes of the data to be automatically learned by means of the experts. Additionally, we encourage the latent representation of our model to follow a Gaussian mixture distribution and to accurately represent the similarities between the data points. We assess the performance of our model on synthetic data, the MNIST benchmark data set, and a challenging real-world task of defining cell subpopulations from mass cytometry (CyTOF) measurements on hundreds of different datasets. MoE-Sim-VAE exhibits superior clustering performance on all these tasks in comparison to the baselines and we show that the MoE architecture in the decoder reduces the computational cost of sampling specific data modes with high fidelity. Copyright © 2019, The Authors. All rights reserved.

关键词： Clustering algorithms

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Improvement Suggestion Performance of Blowing Machine Line 4 with Total Productive Maintenance (TPM) Method at PT. Coca-Cola Amatil Indonesia MedanUnit 1

Improvement Suggestion Performance of Blowing Machine Line 4...

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1st International Conference of SNIKOM 2018, ICoSNIKOM 2018

作者： Irwansyah, Defi Harahap, M.R.F. Erliana, Cut Ita Abdullah, Dahlan Sari, Ayuesteka Siregar, Nurintanasyiah Achmaddaengs, G.S. Indahingwati, Asmara Sumartono, Eko Wilujeng, Sri Nurmawati Subekti, Purwo Kurniasih, Nuning Rosalina, Febrianti Hartono, H. Departement of Industrial Engineering Universitas Malikussaleh Aceh Indonesia Departement of Informatics Universitas Malikussaleh Aceh Indonesia Department of Management STIE Sakti AlamKerinci Jambi Indonesia Department of Management STIE Labuhanbatu Sumatera Utara Indonesia Department of Management Universitas 45 Surabaya Indonesia Department of Management School of Economics Indonesia STIESIA Surabaya Indonesia Faculty of Agriculture Universitas Bengkulu Bengkulu Indonesia Department of Management Faculty of Economy Universitas Kanjuruhan Malang Indonesia Program Study of Industrial Engineering University of 45 Surabaya Indonesia Mechanical Engineering Pasir Pengaraian University Riau Indonesia Faculty of Communication Sciences Library and Information Science Program Universitas Padjadjaran Bandung Indonesia Department of Agrotechnology Universitas Muhammadiyah Sorong Sorong Indonesia Department of Computer Science STMIK IBBI Medan Indonesia

Maintenance is an activity to maintain facilities or equipment of the factory and make repairs or adjustments to the necessary replacement to satisfactory condition of production operations in accordance with what is planned. Companies often experience damage to the Blowing machine so that interconnected machines cannot be operated. The purpose of this study was to improve the performance of Blowing line 4 engines with the Total Productive Maintenance (TPM) method at PT. Coca-Cola Amatil Indonesia Medan Unit, also to determine the level of Blowing machine performance based on the analysis of overall equipment effectiveness (OEE) at PT. Coca-Cola Amatil Indonesia Medan Unit. The method used in this study is the overall equipment effectiveness (OEE) method to measure Ishikawa's treatments and diagrams to compare and propose low engine performance. The results of data processing shows machine maintenance has not comply the OEE standards in July 81.48%, August 81.48%, September 78.07%, October 81.22%, November 78.08%, and those that fill the standards in June amount to 86.48%, with losses that most affect the effectiveness of equipment in line 4 blowroom machine is Equipment Failure Losses of 11.42% based on the results of the study, the proposed improvement in engine performance is to provide training to employees, and increase operator awareness. against engine damage, thus the production process will run smoothly. © Published under licence by IOP Publishing Ltd.

关键词： Data handling

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Application of factor analysis method to support the users acceptance model of ERP systems implementation

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Journal of Physics: Conference Series 2021年第1期1836卷

作者： W Sardjono J Sudirwan W Priatna G R Putra Information Systems Management Department BINUS Graduate Program -Master of Information Systems Management Bina Nusantara University Jakarta Indonesia – 11480 School of Information Systems Department BINUS Undergraduate Program Bina Nusantara University Jakarta Indonesia 11480 Informatics Engineering Engineering Bhayangkara University Jakarta Raya Indonesia Computer Science Study Program Faculty of Mathematics & Natural Sciences Pakuan University Bogor Indonesia

An e-Commerce company has been using an Enterprise Resource Planning (ERP) system for several years, but is still constrained in its implementation, this is reflected in the number of issue/change request tickets submitted by users who have not been able to reach ideal conditions. To overcome this problem, we need an appropriate reference model, the ERP system user acceptance model in companies. The study conducted factors that influence the level of acceptance of SAP ERP users in the XYZ group to then determine a model that is able to explain practically the level of ERP system user acceptance, which in turn can produce concrete proposals to increase ERP system user acceptance. Research is quantitative descriptive using factor analysis and regression analysis methods. The research method uses a questionnaire with a total of 107 valid respondents coming from 8 company names under the XYZ group in 6 Southeast Asian countries. The conclusion of the study is that there are 24 indicators and 4 factors that influence user acceptance of the SAP ERP system. These four factors are the low contribution of the ERP system, the quality of ERP systems and data, the development of ERP systems, and also the low quality of ERP system supporters. It is hoped that by optimizing the value of the 4 factors, the XYZ group can increase user acceptance of the SAP ERP system so that the system can provide benefits expected by the company to be competitive advantage.

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Implementation of Mobile game for Religion Learning

Implementation of Mobile game for Religion Learning

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IEEE International Conference on Teaching, Assessment and Learning for Engineering (TALE)

作者： Edy Sulistiyo Vindy Nizirwan Anwar Diana Teresia Spits Warnars Setya Chendra Wibawa Goenawan Brotosaputro Dedy Prasetya Kristiadi Harco Leslie Hendric Spits Warnars Kiyota Hashimoto Electrical Engineering Department Universitas Negeri Surabaya Jawa Timur Indonesia Game Application & Technology Program School of Computer Science Bina Nusantara University Jakarta Indonesia Faculty of Computer Science Esa Unggul University Jakarta Indonesia Information Systems Department Bina Nusantara University Jakarta Indonesia Informatics Department Universitas Negeri Surabaya Jawa Timur Indonesia Information System Department Universitas Budi Luhur Jakarta Indonesia Computer Science department Raharja University Tangerang Indonesia Computer Science Department BINUS Graduate Program – Doctor of Computer Science Bina Nusantara University Jakarta Indonesia Faculty of Technology and Environment Prince Songkla University Phuket Campus Thailand

ISBN: (数字)9781728126654

ISBN: (纸本)9781728126661

Currently, the growth of information and technology is rapid. It makes a lot of things in various fields including education becoming more effective and efficient. In education, one of its implementation which is a game is proven to be a useful tool to support conventional teaching methods and bring a more natural understanding of learning materials. Moreover, as a product of the popular culture in modern society, video game mirrors the general culture practice in real life and reflects it via its own culture inside the game. This makes a video game can give a contribution to the social construction of reality as it affects the player's view towards learning in real life and vice versa. From there, we see that there is an opportunity for learning about religion to be supported by its utilization to provide an interactive and fun learning experience. In this paper, we discuss how a video game is implemented to support religious learning. The game was developed with the scrum method where we surveyed to gather the user requirements before the design step. The game design was made by using the use case diagram and storyboard, and it was built using Unity version 2017.3.0f3.

关键词： Games Land mobile radio Education computer science Operating systems Information systems Media

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Multidimensional analysis of sensory perception and neurophysiological responses to marinated beef cooked by diverse methods

引用

Innovative Food science and Emerging Technologies 2025年 103卷

作者： Yang, Tianyi Jiang, Wei Luo, Chencheng Hu, Jin Xu, Wei Zhang, Peng Jin, Xiaofei Zhou, Yuxuan Liu, Rui Qian, Zhiyu Yang, Yamin Department of Biomedical Engineering Key Laboratory of Multi-modal Brain-Computer Precision Drive Ministry of Industry and Information Technology Key Laboratory of Brain-Machine Intelligence Technology Ministry of Education Key Laboratory of Digital Medical Equipment and Technology of Jiangsu Province Nanjing University of Aeronautics and Astronautics Nanjing210016 China Program in Neuroscience & Behavioral Disorders Duke-NUS Medical School National University of Singapore Singapore169857 Singapore Department of Neurosurgery Huashan Hospital Shanghai Medical College Fudan University National Center for Neurological Disorders National Key Laboratory of Medical Neurobiology Institutes of Brain Science Shanghai Key Laboratory of Brain Function and Regeneration Institute of Neurosurgery Shanghai200040 China School of Biomedical Engineering and Informatics Nanjing Medical University Nanjing211166 China College of Food Science and Engineering Yangzhou University Yangzhou225127 China

The cooking process significantly influences consumer perception and preference for meat. This study systematically compares the sensory and neurophysiological responses elicited by beef processed via five cooking methods, including boiling (BO), sous-vide (SV), roasting (RO), pan-frying (PF), and deep-frying (DF). Sensory evaluations combining a check-all-that-apply (CATA) questionnaire and hedonic scaling revealed that RO, PF, and DF treatments produced richer flavors and more intense aromas, linked to higher hedonic ratings. In contrast, SV and BO yielded milder sensory profiles with lower flavor intensity and less consumer preference. Electroencephalography (EEG) analysis supported these findings by showing that high-heat methods elicited stronger neural responses, especially in the α, β, and γ frequency bands, which are associated with pleasure, appetite, and cognitive engagement, particularly prominent during olfactory and gustatory tests. Source localization further revealed greater activation in brain regions involved in sensory, reward, memory, emotion, and motivation for high-heat treated beef, demonstrating the connection between enhanced flavor complexity of high-temperature process and consumer appeal. Converging evidence from subjective sensory evaluation and neurophysiological analysis highlights the central role of thermal processing in enhancing food palatability and consumer satisfaction, offering practical insights for improving beef preparation in the food industry. © 2025 Elsevier Ltd

关键词： Neurons

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Cross-platform transcriptomic profiling of the response to recombinant human erythropoietin

Research Square

引用

Research Square 2021年

作者： Wang, Guan Kitaoka, Traci Crawford, Ali Mao, Qian Hesketh, Andrew Guppy, Fergus M. Ash, Garrett I. Liu, Jason Gerstein, Mark B. Pitsiladis, Yannis P. Sport and Exercise Science and Sports Medicine Research and Enterprise Group University of Brighton Brighton United Kingdom Centre for Regenerative Medicine and Devices University of Brighton Brighton United Kingdom Illumina San DiegoCA United States BGI Shenzhen China School of Pharmacy and Biomolecular Sciences University of Brighton Brighton United Kingdom Centre for Stress and Age-related Disease University of Brighton Brighton United Kingdom Veterans Affairs Connecticut Healthcare System West HavenCT United States Center for Medical Informatics Yale University New HavenCT United States Program in Computational Biology & Bioinformatics Yale University New HavenCT United States Department of Molecular Biophysics & Biochemistry Yale University New HavenCT United States Department of Computer Science Yale University New HavenCT United States Department of Statistics and Data Science Yale University New HavenCT United States

RNA-seq has matured and become an important tool for studying RNA biology. Here we compared two RNA-seq (Illumina sequencing by synthesis and MGI DNBSEQTM) and two microarray platforms (Illumina Expression BeadChip and GeneChipTM Human Transcriptome Array 2.0) in healthy individuals administered recombinant human erythropoietin for transcriptome-wide quantification of differential gene expression. The results show that total RNA sequencing combined with DNB-seq produced a multitude of genes of biological relevance and significance in response to recombinant human erythropoietin, in contrast to other platforms. Through data triangulation linking genes to functions, genes representing the processes of erythropoiesis as well as non-erythropoietic functions of erythropoietin were unveiled. This study provides a knowledge base of genes characterising the responses to recombinant human erythropoietin through cross-platform comparison and validation. © 2021, CC BY.

关键词： RNA

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Publisher Correction: Single-sequence protein structure prediction using a language model and deep learning

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Nature biotechnology 2022年第11期40卷 1692页

作者： Ratul Chowdhury Nazim Bouatta Surojit Biswas Christina Floristean Anant Kharkar Koushik Roy Charlotte Rochereau Gustaf Ahdritz Joanna Zhang George M Church Peter K Sorger Mohammed AlQuraishi Laboratory of Systems Pharmacology Program in Therapeutic Science Harvard Medical School Boston MA USA. Laboratory of Systems Pharmacology Program in Therapeutic Science Harvard Medical School Boston MA USA. nazim_bouatta@hms.harvard.edu. Department of Biomedical Informatics Harvard Medical School Boston MA USA. Nabla Bio Inc. Boston MA USA. Department of Computer Science Columbia University New York NY USA. Integrated Program in Cellular Molecular and Biomedical Studies Columbia University New York NY USA. Department of Systems Biology Columbia University New York NY USA. Laboratory of Systems Pharmacology Program in Therapeutic Science Harvard Medical School Boston MA USA. peter_sorger@hms.harvard.edu. Department of Systems Biology Harvard Medical School Boston MA USA. peter_sorger@hms.harvard.edu. Department of Computer Science Columbia University New York NY USA. ma4129@cumc.columbia.edu. Department of Systems Biology Columbia University New York NY USA. ma4129@cumc.columbia.edu.

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Analysis of the BraTS 2023 Intracranial Meningioma Segmentation Challenge

arXiv

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arXiv 2024年

作者： LaBella, Dominic Baid, Ujjwal Khanna, Omaditya McBurney-Lin, Shan McLean, Ryan Nedelec, Pierre Rashid, Arif Tahon, Nourel Hoda Altes, Talissa Bhalerao, Radhika Dhemesh, Yaseen Godfrey, Devon Hilal, Fathi Floyd, Scott Janas, Anastasia Kazerooni, Anahita Fathi Kirkpatrick, John Kent, Collin Kofler, Florian Leu, Kevin Maleki, Nazanin Menze, Bjoern Pajot, Maxence Reitman, Zachary J. Rudie, Jeffrey D. Saluja, Rachit Velichko, Yury Wang, Chunhao Warman, Pranav Adewole, Maruf Albrecht, Jake Anazodo, Udunna Anwar, Syed Muhammad Bergquist, Timothy Chen, Sully Francis Chung, Verena Conte, Gian-Marco Dako, Farouk Eddy, James Ezhov, Ivan Khalili, Nastaran Iglesias, Juan Eugenio Jiang, Zhifan Johanson, Elaine Van Leemput, Koen Li, Hongwei Bran Linguraru, Marius George Liu, Xinyang Mahtabfar, Aria Meier, Zeke Moawad, Ahmed W. Mongan, John Piraud, Marie Shinohara, Russell Takeshi Wiggins, Walter F. Abayazeed, Aly H. Akinola, Rachel Jakab, András Bilello, Michel de Verdier, Maria Correia Crivellaro, Priscila Davatzikos, Christos Farahani, Keyvan Freymann, John Hess, Christopher Huang, Raymond Lohmann, Philipp Moassefi, Mana Pease, Matthew W. Vollmuth, Phillipp Sollmann, Nico Diffley, David Nandolia, Khanak K. Warren, Daniel I. Hussain, Ali Fehringer, Pascal Bronstein, Yulia Deptula, Lisa Stein, Evan G. Taherzadeh, Mahsa de Oliveira, Eduardo Portela Haughey, Aoife Kontzialis, Marinos Saba, Luca Turner, Benjamin Brüßeler, Melanie M.T. Ansari, Shehbaz Gkampenis, Athanasios Weiss, David Maximilian Mansour, Aya Shawali, Islam H. Yordanov, Nikolay Stein, Joel M. Hourani, Roula Moshebah, Mohammed Yahya Abouelatta, Ahmed Magdy Rizvi, Tanvir Willms, Klara Martin, Dann C. Okar, Abdullah D'Anna, Gennaro Taha, Ahmed Sharifi, Yasaman Faghani, Shahriar Kite, Dominic Pinho, Marco Haider, Muhammad Ammar Aristizabal, Alejandro Karargyris, Alexandros Kassem, Hasan Pati, Sarthak Sheller, Micah Alonso-Basanta, Michelle Villanueva-Meyer, Javier Rauschecker, Andreas M. Nada, Ayman Aboian, Mariam Flanders, Adam E. Wiestler, Benedikt Bakas, Spyridon Ca Duke University Medical Center Department of Radiation Oncology DurhamNC United States Division of Computational Pathology Department of Pathology Laboratory Medicine Indiana University School of Medicine IndianapolisIN United States Center for Federated Learning in Medicine Indiana University IndianapolisIN United States Department of Neurosurgery Thomas Jefferson University PhiladelphiaPA United States University of California San FranciscoCA United States Yale University New HavenCT United States Department of Radiation Oncology Perelman School of Medicine University of Pennsylvania PhiladelphiaPA United States University of Missouri ColumbiaMO United States Department of Biostatistics and Health Data Science Indiana University School of Medicine IndianapolisIN United States Children's Hospital of Philadelphia University of Pennsylvania PhiladelphiaPA United States University of Pennsylvania PhiladelphiaPA United States Helmholtz AI Helmholtz Munich Germany Department of Informatics Technical University Munich Germany TranslaTUM - Central Institute for Translational Cancer Research Technical University of Munich Germany Department of Diagnostic and Interventional Neuroradiology School of Medicine Klinikum rechts der Isar Technical University of Munich Germany San FranciscoCA United States Biomedical Image Analysis and Machine Learning Department of Quantitative Biomedicine University of Zurich Switzerland Department of Neuroradiology Technical University of Munich Munich Germany University of San Diego CA United States Cornell University IthacaNY United States Department of Radiology Northwestern University EvanstonIL United States Duke University Medical Center School of Medicine DurhamNC United States Lab Crestview Radiology Lagos Nigeria Sage Bionetworks United States McGill University MontrealQC Canada Children's National Hospital WashingtonDC United States George Washington University WashingtonDC United State

We describe the design and results from the BraTS 2023 Intracranial Meningioma Segmentation Challenge. The BraTS Meningioma Challenge differed from prior BraTS Glioma challenges in that it focused on meningiomas, which are typically benign extra-axial tumors with diverse radiologic and anatomical presentation and a propensity for multiplicity. Nine participating teams each developed deep-learning automated segmentation models using image data from the largest multi-institutional systematically expert annotated multilabel multi-sequence meningioma MRI dataset to date, which included 1000 training set cases, 141 validation set cases, and 283 hidden test set cases. Each case included T2, T2/FLAIR, T1, and T1Gd brain MRI sequences with associated tumor compartment labels delineating enhancing tumor, non-enhancing tumor, and surrounding non-enhancing T2/FLAIR hyperintensity. Participant automated segmentation models were evaluated and ranked based on a scoring system evaluating lesion-wise metrics including dice similarity coefficient (DSC) and 95% Hausdorff Distance. The top ranked team had a lesion-wise median dice similarity coefficient (DSC) of 0.976, 0.976, and 0.964 for enhancing tumor, tumor core, and whole tumor, respectively and a corresponding average DSC of 0.899, 0.904, and 0.871, respectively. These results serve as state-of-the-art benchmarks for future pre-operative meningioma automated segmentation algorithms. Additionally, we found that 1286 of 1424 cases (90.3%) had at least 1 compartment voxel abutting the edge of the skull-stripped image edge, which requires further investigation into optimal pre-processing face anonymization steps. © 2024, CC BY.

关键词： Tumors

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Comparative cellular analysis of motor cortex in human, marmoset and mouse (vol 598, pg 111, 2021)

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NATURE 2022年第7904期604卷 E8-E8页

作者： Bakken, Trygve E. Jorstad, Nikolas L. Hu, Qiwen Lake, Blue B. Tian, Wei Kalmbach, Brian E. Crow, Megan Hodge, Rebecca D. Krienen, Fenna M. Sorensen, Staci A. Eggermont, Jeroen Yao, Zizhen Aevermann, Brian D. Aldridge, Andrew I. Bartlett, Anna Bertagnolli, Darren Casper, Tamara Castanon, Rosa G. Crichton, Kirsten Daigle, Tanya L. Dalley, Rachel Dee, Nick Dembrow, Nikolai Diep, Dinh Ding, Song-Lin Dong, Weixiu Fang, Rongxin Fischer, Stephan Goldman, Melissa Goldy, Jeff Graybuck, Lucas T. Herb, Brian R. Hou, Xiaomeng Kancherla, Jayaram Kroll, Matthew Lathia, Kanan van Lew, Baldur Li, Yang Eric Liu, Christine S. Liu, Hanqing Lucero, Jacinta D. Mahurkar, Anup McMillen, Delissa Miller, Jeremy A. Moussa, Marmar Nery, Joseph R. Nicovich, Philip R. Niu, Sheng-Yong Orvis, Joshua Osteen, Julia K. Owen, Scott Palmer, Carter R. Pham, Thanh Plongthongkum, Nongluk Poirion, Olivier Reed, Nora M. Rimorin, Christine Rivkin, Angeline Romanow, William J. Sedeno-Cortes, Adriana E. Siletti, Kimberly Somasundaram, Saroja Sulc, Josef Tieu, Michael Torkelson, Amy Tung, Herman Wang, Xinxin Xie, Fangming Yanny, Anna Marie Zhang, Renee Ament, Seth A. Behrens, M. Margarita Bravo, Hector Corrada Chun, Jerold Dobin, Alexander Gillis, Jesse Hertzano, Ronna Hof, Patrick R. Hollt, Thomas Horwitz, Gregory D. Keene, C. Dirk Kharchenko, Peter V. Ko, Andrew L. Lelieveldt, Boudewijn P. Luo, Chongyuan Mukamel, Eran A. Pinto-Duarte, Antonio Preiss, Sebastian Regev, Aviv Ren, Bing Scheuermann, Richard H. Smith, Kimberly Spain, William J. White, Owen R. Koch, Christof Hawrylycz, Michael Tasic, Bosiljka Macosko, Evan Z. McCarroll, Steven A. Ting, Jonathan T. Zeng, Hongkui Zhang, Kun Feng, Guoping Ecker, Joseph R. Linnarsson, Sten Lein, Ed S. Allen Institute for Brain Science Seattle WA USA Department of Physiology and Biophysics University of Washington Seattle WA USA Department of Biomedical Informatics Harvard Medical School Boston MA USA Department of Bioengineering University of California San Diego La Jolla CA USA The Salk Institute for Biological Studies La Jolla CA USA Epilepsy Center of Excellence Department of Veterans Affairs Medical Center Seattle WA USA Stanley Institute for Cognitive Genomics Cold Spring Harbor Laboratory Cold Spring Harbor NY USA Department of Genetics Harvard Medical School Boston MA USA Broad Institute of MIT and Harvard Cambridge MA USA LKEB Department of Radiology Leiden University Medical Center Leiden The Netherlands Pattern Recognition and Bioinformatics group Delft University of Technology Delft The Netherlands J. Craig Venter Institute La Jolla CA USA Department of Pathology University of California San Diego CA USA Division of Vaccine Discovery La Jolla Institute for Immunology La Jolla CA USA Genomic Analysis Laboratory The Salk Institute for Biological Studies La Jolla CA USA Computer Science and Engineering Program University of California San Diego La Jolla CA USA Howard Hughes Medical Institute The Salk Institute for Biological Studies La Jolla CA USA Bioinformatics and Systems Biology Graduate Program University of California San Diego La Jolla CA USA Institute for Genomes Sciences University of Maryland School of Medicine Baltimore MD USA Center for Epigenomics Department of Cellular and Molecular Medicine University of California San Diego La Jolla CA USA Ludwig Institute for Cancer Research La Jolla CA USA Department of Computer Science University of Maryland College Park College Park MD USA Sanford Burnham Prebys Medical Discovery Institute La Jolla CA USA Biomedical Sciences Program School of Medicine University of California San Diego La Jolla CA USA University of Connecticut Storrs CT USA Department

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