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6th International Conference on Cybernetics and Intelligent System, ICORIS 2024

作者： Sulistyawan, Jason Sebastian Nugroho, Kuncahyo Setyo Pardamean, Bens Computer Science Department BINUS Graduate Program Bina Nusantara University Jakarta11480 Indonesia Bioinformatics and Data Science Research Center Bina Nusantara University Jakarta11480 Indonesia

ISBN: (纸本)9798331539603

Single-nucleotide polymorphism (SNP) analysis has become a pivotal strategy for drug discovery within bioinformatics, especially for incurable diseases like cancer. With the increasing number of researchers starting to embrace metaheuristic methods, a review was done by gathering papers from the Google Scholar database from 2018 to 2023, which resulted in 20 papers after title, abstract, and content filtering. The findings show that the Genetic Algorithm and the Harmony Search Algorithm have become popular approaches in SNP analysis, particularly in studies on breast cancer, age-related macular degeneration, and colorectal cancer. However, the review shows that while researchers have proven most methods effective in finding disease-related SNPs, a more measurable study in SNP analysis is needed, due to the lack of elaboration on measurement metrics in the found studies. © 2024 IEEE.

关键词： metaheuristic algorithms single nucleotide polymorphisms

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AI-Powered Precision: Revolutionizing Skin Cancer Detection with Advanced Machine Learning 6

AI-Powered Precision: Revolutionizing Skin Cancer Detection ...

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6th IEEE Novel Intelligent and Leading Emerging sciences Conference, NILES 2024

作者： Abd-Elaziz, Mariam M. Elshafie, Basma M. Abdullah, Hagar Gerges, Karen Y. Ghanem, Ingy A. Fouad, Khaled M. El-Ghamry, Amir Moawad, Ibrahim F. El-Metwally, Sara New Mansoura University Faculty of Computer Science and Engineering Dakahlia Egypt Mansoura University New Mansoura University Faculty of Engineering Computer and Communication Program Faculty of Computer Science and Engineering Egypt Benha University Information Systems Faculty of Computers and Artificial Intelligence Egypt Mansoura University New Mansoura University Faculty of Computer and Information Sciences Faculty of Computer Science and Engineering Egypt School of Engineering and Computer Science University of Hertfordshire Gaf Egypt Ain Shams University Faculty of Computer and Information Sciences Cairo Egypt College of Computer Science and Engineering Taibah University Department of Artificial Intelligence Medina42353 Saudi Arabia

ISBN: (纸本)9798350378511

Skin cancer's increasing incidence rates necessitate advanced diagnostic tools. This research uses MobileNet architecture to develop an enhanced system for skin cancer detection. MobileNet's efficient CNN architecture, combined with Keras for model lifecycle management and TensorFlow for real-time inference, forms the foundation of this study. Using 10,015 dermatoscopic pictures from seven different classifications of skin cancer in the HAM10000 dataset, the methodology includes several key stages: image preprocessing to correct illumination and adjust resolution, data augmentation to balance the dataset, and model training using Transfer Learning. The MobileNet model was trained over 50 epochs with a comprehensive architecture incorporating multiple specialized layers. By combining large-scale data analysis and adaptive learning, this methodology demonstrates The revolutionary possibilities of AI and ML in improving skin cancer diagnostics and public health outcomes. Keywords Skin Cancer Detection, Dermatoscopic Images, Machine Learning, Deep Learning © 2024 IEEE.

关键词： Adversarial machine learning

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Semi-automated meningioma segmentation with bounding boxes 9th

Semi-automated meningioma segmentation with bounding boxes

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9th International Conference on computer science and Computational Intelligence, ICCSCI 2024

作者： Heryanto, Nur Adhianti Isnan, Mahmud Henry, Matthew Martianus Pardamean, Bens Bioinformatics and Data Science Research Center Bina Nusantara University Jakarta11480 Indonesia Computer Science Department BINUS Graduate Program Bina Nusantara University Jakarta11480 Indonesia

Segmentation is manually performed by physicians, which takes considerable time and may be subject to observers. Automating this task can increase efficiency and consistency. Existing studies on meningioma segmentation used data from limited study centers, indicating the need for research on multi-center data to assess generalizability. In this work, two semi-automated methods with bounding box priors, LiteMedSAM and BBU-Net, are evaluated on the brain tumor segmentation (BraTS) 2023 meningioma dataset collected from five study-centers. Preprocessing included exclusion of small tumors, z-score normalization, and extraction of slices that contain tumors, generating 25,602 2D axial magnetic resonance imaging (MRI) scans. A fine-tuning strategy is adopted for LiteMedSAM while BBU-Net is trained from scratch. The models are evaluated using a five-fold cross-validation, with data split at the case level. Results show that while U-Net models can achieve performance close to LiteMedSAM, the foundation model has overall better performance, with more than 90% in all evaluation scores. © 2024 The Authors.

关键词： Magnetic resonance imaging

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Evaluating the Effectiveness of Transformer Models for Molecular Property Prediction: A Review 9

Evaluating the Effectiveness of Transformer Models for Molec...

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9th International Conference on Information Technology and Digital Applications, ICITDA 2024

作者： Imani, Alyssa Pardamean, Bens Bioinformatics and Data Science Research Center Bina Nusantara University Jakarta11480 Indonesia Binus Graduate Program Bina Nusantara University Computer Science Departement Jakarta11480 Indonesia

ISBN: (纸本)9798331510732

Transformer models, originally successful in natural language processing, are now being applied to chemical and biological studies, excelling in areas such as molecular property prediction, material science, and drug discovery. BERT, a Transformer-based model, has become foundational in cheminformatics, particularly for QSAR (Quantitative Structure-Activity Relationship) modeling and ADMET (Absorption, Distribution, Metabolism, Excretion, and Toxicity) evaluations in drug discovery. However, achieving higher accuracy often requires designing more complex models, which can compromise their interpretability. This posing a challenge for researchers who need to understand the reasoning behind the predictions. The trade-off between accuracy and interpretability presents a critical challenge in applying black box models to real-world problems in cheminformatics. This work compares Transformer-based models with traditional machine learning and deep learning approaches, focusing on both interpretability and performance. The goal is to highlight the strengths and limitations of each method, offering insights into their optimal use in drug discovery and material science. © 2024 IEEE.

关键词： Prediction models

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A Performance Optimization of Quantum Computing Simulation using FPGA 19

A Performance Optimization of Quantum Computing Simulation u...

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19th International Conference on Electrical Engineering/Electronics, computer, Telecommunications and Information Technology, ECTI-CON 2022

作者： Jungjarassub, Yaninee Piromsopa, Krerk Chulalongkorn University Computer Science Program Department of Computer Engineering Faculty of Engineering Bangkok Thailand

ISBN: (纸本)9781665485845

We use FPGA to optimize the simulation of quantum computing in two aspects. (a) The if-else state is used in place of tensor product calculation. This allows the tensor product of each quantum operator to be generated in a single clock cycle. (b) The pre-calculated lookup ROM is used for estimating the sine and cosine values. This facilitates the computation of quantum gates that are related to angle. To validate our work, we implement our design in VerilogHDL. The performance is evaluated using an FPGA simulator. The result shows a dramatic improvement in the simulation process comparing to those of simulation on classical computers. © 2022 IEEE.

关键词： Field programmable gate arrays (FPGA)

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LDA Topic Modeling for Bioinformatics Terms in arXiv Documents 9th

LDA Topic Modeling for Bioinformatics Terms in arXiv Documen...

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9th International Conference on computer science and Computational Intelligence, ICCSCI 2024

作者： Karnyoto, Andrea Stevens Henry, Matthew Martianus Pardamean, Bens Bioinformatics and Data Science Research Center Bina Nusantara University Jakarta11480 Indonesia Computer Science Department BINUS Graduate Program Bina Nusantara University Jakarta11480 Indonesia

A wide variety of disciplines contribute to bioinformatics research, including computer science, biology, chemistry, mathematics, and physics. This study determines the number of research articles published on arXiv classified as bioinformatics topics and the most frequently used bioinformatics terms using topic modeling, Latent Dirichlet Allocation (LDA). An algorithm based on LDA is used to discover topics hidden within large collections of documents through the use of statistical analysis. Our research examined 226453 articles on arXiv between January 2023 and January 2024. As a result, there are more than 10521 articles categorized into bioinformatics topics. Most commonly, 6352 documents are in the "Mathematical Physics" category. The second most popular category is "computer science," with 2950 documents. Accordingly, the terms 'RNA,' 'sequence,' 'tree,' and 'homology' are the three most commonly used terms in bioinformatics. The study of RNA plays a vital role in molecular biology;thus, the study of RNA is prevalent in bioinformatics. Sequential data refer to the order in which nucleotides or amino acids can be found in a DNA molecule or a protein. © 2024 The Authors.

关键词： arXiv bioinformatics Latent Dirichlet Allocation

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Analysis of the 5Rs in Thailand Medication Error Classification through Natural Language Processing 20

Analysis of the 5Rs in Thailand Medication Error Classificat...

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20th International Joint Conference on computer science and Software Engineering, JCSSE 2023

作者： Udomnuchaisup, Peachyasitt Imsombut, Aurawan Suwannahitatorn, Picha Saethang, Thammakorn Kasetsart University Biomedical Data Science Master's Program Faculty of Science Bangkok Thailand Kasetsart University Faculty of Science Department of Computer Science Bangkok Thailand Bangkok Thailand

ISBN: (纸本)9798350300505

Medication errors threaten patient safety considerably, underscoring the necessity for enhanced detection and prevention techniques. A prevalent classification system in hospitals relies on the standard practice of medication administration known as the Five Rights (5R). This study seeks to develop an NLP-based tool designed to expand 5R error categorization coverage and alleviate the workload of medical professionals. The proposed method focuses on Thai medical text, incorporating Thai and English vocabulary. In this investigation, we developed a supervised learning classification framework using the Universal Sentence Encoder (USE) for sentence embedding, followed by an Artificial Neural Network (ANN) for model training. Additionally, we explored a zero-shot classification model employing pre-trained Large Language Models (PLMs). Our findings reveal that the supervised learning classification model provides the most favorable performance, albeit with the limitation of reliance on labeled datasets, which can be resource intensive. Conversely, the zero-shot classification framework's performance is less optimal. However, future advancements in Thai medical PLMs may improve efficacy and present a viable alternative for medical data analysis without dependence on labeled datasets. This initiative lays the groundwork for potential future applications and advantages within Thailand's medical domain. © 2023 IEEE.

关键词： Neural networks

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Confidentiality. Integrity, and Availability (CIA) Approach for Private Dataset Management System Design 9

Confidentiality. Integrity, and Availability (CIA) Approach ...

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9th International Conference on Information Technology and Digital Applications, ICITDA 2024

作者： Isnan, Mahmud Elwirehardja, Gregorius Natanael Ariansyah, Dedy Rahutomo, Reza Pardamean, Bens School of Computer Science Bina Nusantara University Computer Science Department Jakarta11480 Indonesia Bioinformatics and Data Science Research Center Bina Nusantara University Jakarta11480 Indonesia School of Information Systems Bina Nusantara University Information Systems Department Jakarta11480 Indonesia Binus Graduate Program Bina Nusantara University Computer Science Department Jakarta11480 Indonesia

ISBN: (纸本)9798331510732

Dataset management systems are essential for assisting research and development (R&D) organizations in applying data governance protocols, especially in managing the utilization of datasets. In R&D, datasets are vital sources for producing analysis, machine learning prediction, and supporting decision-making. As such, it is important to deploy dataset management systems with considerations regarding the aspects of Confidentiality, Integrity, and Availability (CIA) which is a design principle that emphasized information protection and collaboration facilitation among dataset users. The study proposed an analysis and a design for a dataset management system that takes CIA aspects into account. In the future, the proposed design will be utilized as a benchmark for building a dataset management system. In this study, the Waterfall method was adopted. A use case diagram, an ERD (Entity Relationship Diagram), and an activity diagram were constructed in the design stage. In the project implementation stage, the Laravel framework including Laravel Jetstream was considered to be used. © 2024 IEEE.

关键词： Data integrity

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An Evaluation Of Hospital Accreditation From The Survey With Text Vector Analysis Techniques 20

An Evaluation Of Hospital Accreditation From The Survey With...

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20th International Joint Conference on computer science and Software Engineering, JCSSE 2023

作者： Prapunwattana, Dittaphong Imsombut, Aurawan Suwannahitatorn, Picha Saethang, Thammakorn Kasetsart University Biomedical Data Science Master's Program Faculty of Science Bangkok Thailand Kasetsart University Faculty of Science Department of Computer Science Bangkok Thailand Bangkok Thailand

ISBN: (纸本)9798350300505

The Healthcare Accreditation Institute has an assessment and certification process for hospitals applying for Healthcare Accreditation. The assessment process requires a large number of text-based reports. The purpose of this research was to study the text analysis of the self-assessment reports of healthcare facilities and surveyor reports on issues related to the pharmaceutical system to evaluate and rate the accreditation of medical facilities. The natural language text vector analysis technique, together with the Universal Sentence Encoder (USE) was compared to Learning Lightweight Language-agnostic Sentence Embeddings (LEALLA) for encoding data into a high-dimensional format. Next the sentence encoding feature was fed through a machine learning procedure, including artificial neural networks, logistic regression, and support vector machines to classify nursing facility accreditation ratings. The experimental results showed that the USE embedding yielded better performance than the LEALLA embedding across all models with a precision of 0.70 but took slightly longer to encode feature sentences. This research could improve the performance of the analysis and scoring. © 2023 IEEE.

关键词： Embeddings

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Variational quantum neural network with optimized ansatz for predicting malignant ventricular arrhythmias

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Procedia computer science 2024年 245卷 109-116页

作者： Nicholas Dominic Bens Pardamean Bioinformatics and Data Science Research Center Bina Nusantara University Jakarta 11480 Indonesia Computer Science Department BINUS Graduate Program – Master of Computer Science Program Bina Nusantara University Jakarta 11480 Indonesia

Preventive strategies should be the utmost priority when dealing with diverse patients suffering from malignant ventricular arrhythmia (MVA) that can lead to sudden cardiac death (SCD). Electrocardiogram (ECG) data is commonly used as a predictor for MVA predictive models. In this study, all ECG signals from MIT-BIH databases were fragmented into five-minute durations with a frequency sampling of 128 Hz. To solve the absence of hybrid optimizations in Machine Learning (ML) models, a novel Variational Quantum Neural Network (VQNN) was invented. Empowered by deep learning capabilities and optimized quantum circuits design, VQNN achieved remarkable performances designated by an accuracy of up to 95.1%, a perfect 100% recall, and a 95.2% score of the area under the Receiver Operating Characteristic curve (AUC ROC) with Conjugate Gradient as an optimizer and EfficientSU2 as a quantum ansatz. Despite the susceptibility to quantum noise, this research settles a new trajectory of utilizing quantum variational algorithms to predict and expand its applicability for MVA cases.

关键词： Malignant Ventricular Arrhythmia Sudden Cardiac Death Variational Quantum Algorithm Quantum Computing Neural Network

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