Drug-target interactions(DTIs) prediction plays an important role in the process of drug *** computational methods treat it as a binary prediction problem, determining whether there are connections between drugs and t...
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Drug-target interactions(DTIs) prediction plays an important role in the process of drug *** computational methods treat it as a binary prediction problem, determining whether there are connections between drugs and targets while ignoring relational types information. Considering the positive or negative effects of DTIs will facilitate the study on comprehensive mechanisms of multiple drugs on a common target, in this work, we model DTIs on signed heterogeneous networks, through categorizing interaction patterns of DTIs and additionally extracting interactions within drug pairs and target protein pairs. We propose signed heterogeneous graph neural networks(SHGNNs), further put forward an end-to-end framework for signed DTIs prediction, called SHGNN-DTI,which not only adapts to signed bipartite networks, but also could naturally incorporate auxiliary information from drug-drug interactions(DDIs) and protein-protein interactions(PPIs). For the framework, we solve the message passing and aggregation problem on signed DTI networks, and consider different training modes on the whole networks consisting of DTIs, DDIs and PPIs. Experiments are conducted on two datasets extracted from Drug Bank and related databases, under different settings of initial inputs, embedding dimensions and training modes. The prediction results show excellent performance in terms of metric indicators, and the feasibility is further verified by the case study with two drugs on breast cancer.
Sentiment analysis plays an important role in distilling and clarifying content from movie reviews,aiding the audience in understanding universal views towards the ***,the abundance of reviews and the risk of encounte...
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Sentiment analysis plays an important role in distilling and clarifying content from movie reviews,aiding the audience in understanding universal views towards the ***,the abundance of reviews and the risk of encountering spoilers pose challenges for efcient sentiment analysis,particularly in Arabic *** study proposed a Stochastic Gradient Descent(SGD)machine learning(ML)model tailored for sentiment analysis in Arabic and English movie *** allows for fexible model complexity adjustments,which can adapt well to the Involvement of Arabic language *** adaptability ensures that the model can capture the nuances and specifc local patterns of Arabic text,leading to better *** distinct language datasets were utilized,and extensive pre-processing steps were employed to optimize the datasets for *** proposed SGD model,designed to accommodate the nuances of each language,aims to surpass existing models in terms of accuracy and *** SGD model achieves an accuracy of 84.89 on the Arabic dataset and 87.44 on the English dataset,making it the top-performing model in terms of accuracy on both *** indicates that the SGD model consistently demonstrates high accuracy levels across Arabic and English *** study helps deepen the understanding of sentiments across various linguistic *** many studies that focus solely on movie reviews,the Arabic dataset utilized here includes hotel reviews,ofering a broader perspective.
In the last decade, technical advancements and faster Internet speeds have also led to an increasing number ofmobile devices and users. Thus, all contributors to society, whether young or old members, can use these mo...
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In the last decade, technical advancements and faster Internet speeds have also led to an increasing number ofmobile devices and users. Thus, all contributors to society, whether young or old members, can use these mobileapps. The use of these apps eases our daily lives, and all customers who need any type of service can accessit easily, comfortably, and efficiently through mobile apps. Particularly, Saudi Arabia greatly depends on digitalservices to assist people and visitors. Such mobile devices are used in organizing daily work schedules and services,particularly during two large occasions, Umrah and Hajj. However, pilgrims encounter mobile app issues such asslowness, conflict, unreliability, or user-unfriendliness. Pilgrims comment on these issues on mobile app platformsthrough reviews of their experiences with these digital services. Scholars have made several attempts to solve suchmobile issues by reporting bugs or non-functional requirements by utilizing user ***, solving suchissues is a great challenge, and the issues still exist. Therefore, this study aims to propose a hybrid deep learningmodel to classify and predict mobile app software issues encountered by millions of pilgrims during the Hajj andUmrah periods from the user perspective. Firstly, a dataset was constructed using user-generated comments fromrelevant mobile apps using natural language processing methods, including information extraction, the annotationprocess, and pre-processing steps, considering a multi-class classification problem. Then, several experimentswere conducted using common machine learning classifiers, Artificial Neural Networks (ANN), Long Short-TermMemory (LSTM), and Convolutional Neural Network Long Short-Term Memory (CNN-LSTM) architectures, toexamine the performance of the proposed model. Results show 96% in F1-score and accuracy, and the proposedmodel outperformed the mentioned models.
Acute Bilirubin Encephalopathy(ABE)is a significant threat to neonates and it leads to disability and high mortality *** and treating ABE promptly is important to prevent further complications and long-term *** studie...
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Acute Bilirubin Encephalopathy(ABE)is a significant threat to neonates and it leads to disability and high mortality *** and treating ABE promptly is important to prevent further complications and long-term *** studies have explored ABE ***,they often face limitations in classification due to reliance on a single modality of Magnetic Resonance Imaging(MRI).To tackle this problem,the authors propose a Tri-M2MT model for precise ABE detection by using tri-modality MRI *** scans include T1-weighted imaging(T1WI),T2-weighted imaging(T2WI),and apparent diffusion coefficient maps to get indepth ***,the tri-modality MRI scans are collected and preprocessesed by using an Advanced Gaussian Filter for noise reduction and Z-score normalisation for data *** Advanced Capsule Network was utilised to extract relevant features by using Snake Optimization Algorithm to select optimal features based on feature correlation with the aim of minimising complexity and enhancing detection ***,a multi-transformer approach was used for feature fusion and identify feature correlations ***,accurate ABE diagnosis is achieved through the utilisation of a SoftMax *** performance of the proposed Tri-M2MT model is evaluated across various metrics,including accuracy,specificity,sensitivity,F1-score,and ROC curve analysis,and the proposed methodology provides better performance compared to existing methodologies.
Roadside and outside environmental elements contribute to the road traffic setting's highly dynamic and turbulent nature. The human factor, primarily disregarded in the present research, is an essential element th...
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Roadside and outside environmental elements contribute to the road traffic setting's highly dynamic and turbulent nature. The human factor, primarily disregarded in the present research, is an essential element that contributes to the traffic context in addition to infrastructure-related elements like traffic signals, road infrastructure, and other road networks. Timing the green light and tracing the object that makes the incorrect turn using real-time visual information for traffic monitoring are still challenging tasks for the conventional traffic control system. We describe a self-adaptive real-time algorithm based on real-time traffic flow and monitoring. Combining image processing with AI-powered, self-adaptive machine learning for controlling traffic clearance at intersections is a forward-thinking approach with great potential. The suggested system uses the You Only Look Once v3 (YOLOv3) model and single image processing using a neural network to determine traffic clearance at the signal. YOLOv3 method to recognize objects from video frames. Subsequently, the centroid object tracking technique is used to monitor the movement of each vehicle within a proposed framework. We implemented algorithms to identify vehicles traveling in the incorrect direction based on their trajectories. This integrated approach enhances accurate object recognition, real-time vehicle tracking, and the detection of traffic violations, enhancing overall road safety measures. The experimental findings are quite promising, achieving an exclusive comparison between expected and actual vehicle numbers is crucial for any traffic monitoring system. The average object detection accuracy of 88.43% is impressive, and the exceptional 90.45% accuracy in tracking vehicles engaging in wrong turns or reckless driving behaviors is particularly noteworthy—it provides the system's ability to address safety concerns effectively. Integrating a Convolutional Neural Network (CNN) into the algorithm to all
Data collection using mobile sink(s) has proven to reduce energy consumption and enhance the network lifetime of wireless sensor networks. Generally speaking, a mobile sink (MS) traverses the network region, sojournin...
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Advancements in smart applications highlight the need for increased processing and storage capacity at Smart Devices (SDs). To tackle this, Edge computing (EC) is enabled to offload SD workloads to distant edge server...
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In this paper, we delve into the transformative landscape of education amidst the disruptive advances of generative AI (GenAI), characterized by an unprecedented capacity to generate new information with tools such as...
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As modern communication technology advances apace,the digital communication signals identification plays an important role in cognitive radio networks,the communication monitoring and management *** has become a promi...
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As modern communication technology advances apace,the digital communication signals identification plays an important role in cognitive radio networks,the communication monitoring and management *** has become a promising solution to this problem due to its powerful modeling capability,which has become a consensus in academia and ***,because of the data-dependence and inexplicability of AI models and the openness of electromagnetic space,the physical layer digital communication signals identification model is threatened by adversarial *** examples pose a common threat to AI models,where well-designed and slight perturbations added to input data can cause wrong ***,the security of AI models for the digital communication signals identification is the premise of its efficient and credible *** this paper,we first launch adversarial attacks on the end-to-end AI model for automatic modulation classifi-cation,and then we explain and present three defense mechanisms based on the adversarial *** we present more detailed adversarial indicators to evaluate attack and defense ***,a demonstration verification system is developed to show that the adversarial attack is a real threat to the digital communication signals identification model,which should be paid more attention in future research.
Security and privacy are major concerns in this modern world. Medical documentation of patient data needs to be transmitted between hospitals for medical experts opinions on critical cases which may cause threats to t...
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Security and privacy are major concerns in this modern world. Medical documentation of patient data needs to be transmitted between hospitals for medical experts opinions on critical cases which may cause threats to the data. Nowadays most of the hospitals use electronic methods to store and transmit data with basic security measures, but these methods are still vulnerable. There is no perfect solution that solves the security problems in any industry, especially healthcare. So, to cope with the arising need to increase the security of the data from being manipulated the proposed method uses a hybrid image encryption technique to hide the data in an image so it becomes difficult to sense the presence of data in the image while transmission. It combines Least Significant Bit (LSB) Algorithm using Arithmetic Division Operation along with Canny edge detection to embed the patient data in medical images. The image is subsequently encrypted using keys of six different chaotic maps sequentially to increase the integrity and robustness of the system. Finally, an encrypted image is converted into DNA sequence using DNA encoding rule to improve reliability. The experimentation is done on the Chest XRay image, Knee Magnetic Resonance Imaging (MRI) image, Neck MRI image, Lungs Computed Tomography (CT) Scan image datasets and patient medical data with 500 characters, 1000 characters and 1500 characters. And, it is evaluated based on time coefficient of encryption and decryption, histogram, entropy, similarity score (Mean Square Error), quality score (peak signal-to-noise ratio), motion activity index (number of changing pixel rate), unified average changing intensity, image similarity score (structure similarity index measurement) between original and encrypted images. Also, the proposed technique is compared with other recent state of arts methods for 500 characters embedding and performed better than those techniques. The proposed method is more stable and embeds comparativel
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