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An Encoding-Decoding Framework Based on CNN for circ RNA-RBP Binding Sites Prediction

Chinese Journal of Electronics 2024年第1期33卷 256-263页

作者： Yajing GUO Xiujuan LEI Yi PAN School of Computer Science Shaanxi Normal University Faculty of Computer Science and Control Engineering Shenzhen Institute of Advanced TechnologyChinese Academy of Sciences Department of Computer Science Georgia State University

Predicting RNA binding protein(RBP) binding sites on circular RNAs(circ RNAs) is a fundamental step to understand their interaction mechanism. Numerous computational methods are developed to solve this problem, but they cannot fully learn the features. Therefore, we propose circ-CNNED, a convolutional neural network(CNN)-based encoding and decoding framework. We first adopt two encoding methods to obtain two original matrices. We preprocess them using CNN before fusion. To capture the feature dependencies, we utilize temporal convolutional network(TCN) and CNN to construct encoding and decoding blocks, respectively. Then we introduce global expectation pooling to learn latent information and enhance the robustness of circ-CNNED. We perform circ-CNNED across 37 datasets to evaluate its effect. The comparison and ablation experiments demonstrate that our method is superior. In addition, motif enrichment analysis on four datasets helps us to explore the reason for performance improvement of circ-CNNED.

关键词： Circular RNAs (circRNAs) RNA binding proteins Convolutional neural network Temporal convolutional network Encoder-decoder network

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AsyCo: an asymmetric dual-task co-training model for partial-label learning

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science China(Information sciences) 2025年第5期68卷 332-347页

作者： Beibei LI Yiyuan ZHENG Beihong JIN Tao XIANG Haobo WANG Lei FENG College of Computer Science Chongqing University State Key Laboratory of Computer Science Institute of Software Chinese Academy of Sciences University of Chinese Academy of Sciences School of Software Technology Zhejiang University School of Computer Science and Engineering Nanyang Technological University

Partial-label learning(PLL) is a typical problem of weakly supervised learning, where each training instance is annotated with a set of candidate labels. Self-training PLL models achieve state-of-the-art performance but suffer from error accumulation problems caused by mistakenly disambiguated instances. Although co-training can alleviate this issue by training two networks simultaneously and allowing them to interact with each other, most existing co-training methods train two structurally identical networks with the same task, i.e., are symmetric, rendering it insufficient for them to correct each other due to their similar limitations. Therefore, in this paper, we propose an asymmetric dual-task co-training PLL model called AsyCo,which forces its two networks, i.e., a disambiguation network and an auxiliary network, to learn from different views explicitly by optimizing distinct tasks. Specifically, the disambiguation network is trained with a self-training PLL task to learn label confidence, while the auxiliary network is trained in a supervised learning paradigm to learn from the noisy pairwise similarity labels that are constructed according to the learned label confidence. Finally, the error accumulation problem is mitigated via information distillation and confidence refinement. Extensive experiments on both uniform and instance-dependent partially labeled datasets demonstrate the effectiveness of AsyCo.

关键词： machine learning weakly supervised learning partial-label learning co-training models candidate label sets

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An efficient schedulability analysis based on worst-case interference time for real-time systems

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science China(Information sciences) 2024年第9期67卷 88-104页

作者： Hongbiao LIU Mengfei YANG Lei QIAO Xi CHEN Jian GONG School of Computer Science and Technology Xidian University China Academy of Space Technology Beijing Institute of Control Engineering

Real-time systems are widely implemented in the Internet of Things(IoT) and safety-critical systems, both of which have generated enormous social value. Aiming at the classic schedulability analysis problem in real-time systems, we proposed an exact Boolean analysis based on interference(EBAI) for schedulability analysis in real-time systems. EBAI is based on worst-case interference time(WCIT), which considers both the release jitter and blocking time of the task. We improved the efficiency of the three existing tests and provided a comprehensive summary of related research results in the field. Abundant experiments were conducted to compare EBAI with other related results. Our evaluation showed that in certain cases, the runtime gain achieved using our analysis method may exceed 73% compared to the stateof-the-art schedulability test. Furthermore, the benefits obtained from our tests grew with the number of tasks, reaching a level suitable for practical application. EBAI is oriented to the five-tuple real-time task model with stronger expression ability and possesses a low runtime overhead. These characteristics make it applicable in various real-time systems such as spacecraft, autonomous vehicles, industrial robots, and traffic command systems.

关键词： five-tuple real-time task model real-time system spacecraft Internet of Things exact schedulability analysis worst-case interference time

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Smart Contract Based Carpooling Application for Secure and Efficient Ride Sharing 3

Smart Contract Based Carpooling Application for Secure and E...

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3rd IEEE International Conference on Recent Advances in Systems science and engineering, RASSE 2023

作者： Ramani Bai, V. Sudhir, Pranav Joshi, Rashmi Nair, Vighnesh Anilkumar, Vishnu Vidya Academy of Science and Technology Department of Computer Science Engineering Kerala Thrissur India

ISBN: (纸本)9798350341676

Carpooling offers an effective solution to mitigate pollutant emissions and alleviate traffic congestion. This paper presents a novel system designed to address the shortcomings of centralized ride-sharing services by leveraging smart contracts. By ensuring data security, confidentiality, and privacy, the proposed system initiates the decentralization process for carpooling systems. Users can assume the role of either a driver or a passenger, enabling them to publish rides or search for and book desired rides. Smart contracts facilitate seamless execution of user requests, triggered by events such as ride creation or booking. The fare calculation is based on the passenger's route distance, current fuel price, and the driver's car mileage, resulting in significantly reduced costs. Upon booking a ride, the fare amount is debited from the passenger and credited to the driver only upon the passenger reaching their destination. The system's overarching objective is to simplify people's lives by minimizing travel expenses and traffic congestion, all while upholding user security. © 2023 IEEE.

关键词： Smart contract

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Drug-Target Interactions Prediction Based on Signed Heterogeneous Graph Neural Networks

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Chinese Journal of Electronics 2024年第1期33卷 231-244页

作者： Ming CHEN Yajian JIANG Xiujuan LEI Yi PAN Chunyan JI Wei JIANG College of Information Science and Engineering Hunan Normal University School of Computer Science Shaanxi Normal University Faculty of Computer Science and Control Engineering Shenzhen Institute of Advanced TechnologyChinese Academy of Sciences Computer Science Department BNU-HKBU United International College

Drug-target interactions(DTIs) prediction plays an important role in the process of drug *** computational methods treat it as a binary prediction problem, determining whether there are connections between drugs and targets while ignoring relational types information. Considering the positive or negative effects of DTIs will facilitate the study on comprehensive mechanisms of multiple drugs on a common target, in this work, we model DTIs on signed heterogeneous networks, through categorizing interaction patterns of DTIs and additionally extracting interactions within drug pairs and target protein pairs. We propose signed heterogeneous graph neural networks(SHGNNs), further put forward an end-to-end framework for signed DTIs prediction, called SHGNN-DTI,which not only adapts to signed bipartite networks, but also could naturally incorporate auxiliary information from drug-drug interactions(DDIs) and protein-protein interactions(PPIs). For the framework, we solve the message passing and aggregation problem on signed DTI networks, and consider different training modes on the whole networks consisting of DTIs, DDIs and PPIs. Experiments are conducted on two datasets extracted from Drug Bank and related databases, under different settings of initial inputs, embedding dimensions and training modes. The prediction results show excellent performance in terms of metric indicators, and the feasibility is further verified by the case study with two drugs on breast cancer.

关键词： Drug-target interactions Signed heterogeneous network Link sign prediction Graph neural networks

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A novel hybrid authentication protocol utilizing lattice-based cryptography for IoT devices in fog networks

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Digital Communications and Networks 2024年第4期10卷 989-1000页

作者： Kumar Sekhar Roy Subhrajyoti Deb Hemanta Kumar Kalita Department of Computer Science and Engineering Manipal Institute of Technology BengaluruManipal Academy of Higher EducationManipal576104KarnatakaIndia Department of Computer Science&Engineering ICFAI UniversityAgartala799210India Department of Computer Science&Engineering Central Institute of TechnologyKokrajhar783370India

The Internet of Things(IoT)has taken the interconnected world by *** to their immense applicability,IoT devices are being scaled at exponential proportions ***,very little focus has been given to securing such *** these devices are constrained in numerous aspects,it leaves network designers and administrators with no choice but to deploy them with minimal or no security at *** have seen distributed denial-ofservice attacks being raised using such devices during the infamous Mirai botnet attack in *** we propose a lightweight authentication protocol to provide proper access to such *** have considered several aspects while designing our authentication protocol,such as scalability,movement,user registration,device registration,*** define the architecture we used a three-layered model consisting of cloud,fog,and edge *** have also proposed several pre-existing cipher suites based on post-quantum cryptography for evaluation and *** also provide a fail-safe mechanism for a situation where an authenticating server might fail,and the deployed IoT devices can self-organize to keep providing services with no human *** find that our protocol works the fastest when using ring learning with *** prove the safety of our authentication protocol using the automated validation of Internet security protocols and applications *** conclusion,we propose a safe,hybrid,and fast authentication protocol for authenticating IoT devices in a fog computing environment.

关键词： Internet of things Authentication Post-quantum cryptography Lattice-based cryptography Cloud computing Fog computing Fail-safe

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Predicting circRNA-Disease Associations by Using Multi-Biomolecular Networks Based on Variational Graph Auto-Encoder with Attention Mechanism

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Chinese Journal of Electronics 2024年第6期33卷 1526-1537页

作者： Jing YANG Xiujuan LEI Yi PAN School of Computer Science Shaanxi Normal University Faculty of Computer Science and Control Engineering Shenzhen Institute of Advanced TechnologyChinese Academy of Sciences Shenzhen Key Laboratory of Intelligent Bioinformatics Shenzhen Institute of Advanced Technology

CircRNA-disease association(CDA) can provide a new direction for the treatment of diseases. However,traditional biological experiment is time-consuming and expensive, this urges us to propose the reliable computational model to predict the associations between circRNAs and diseases. And there is existing more and more evidence indicates that the combination of multi-biomolecular information can improve the prediction accuracy. We propose a novel computational model for CDA prediction named MBCDA, we collect the multi-biomolecular information including circRNA, disease, miRNA and lncRNA based on 6 databases, and construct three heterogeneous network among them, then the multi-heads graph attention networks are applied to these three networks to extract the features of circRNAs and diseases from different views, the obtained features are put into variational graph auto-encoder(VGAE) network to learn the latent distributions of the nodes, a fully connected neural network is adopted to further process the output of VGAE and uses sigmoid function to obtain the predicted probabilities of circRNA-disease *** a result, MBCDA achieved the values of AUC and AUPR under 5-fold cross-validation of 0.893 and 0.887. MBCDA was applied to the analysis of the top-25 predicted associations between circRNAs and diseases, these experimental results show that our proposed MBCDA is a powerful computational model for CDA prediction.

关键词： Knowledge engineering Attention mechanisms Computational modeling Biological system modeling Predictive models Feature extraction Heterogeneous networks Topology Data mining Diseases

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IoT-Based Smart Waste Management System with Level Indicators for Effective Garbage Waste Segregation 3

IoT-Based Smart Waste Management System with Level Indicator...

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3rd IEEE International Conference on Distributed Computing and Electrical Circuits and Electronics, ICDCECE 2024

作者： Varghese, Mary P. Anooja, V.S. Akhila, R. Krishnakumar, M. Xavier, Arun Vidya Academy Of Science & Technology Department Of Electrical & Electronics Engineering Thrissur India

ISBN: (纸本)9798350318609

The rapid growth in urbanization and population has increased the generation of municipal solid garbage, providing significant challenges to waste management systems. Hence, to solve the issues in waste management, it suggested Internet of Things (IoT) smart-based Smart Waste Management (SWM) with level indications. This system combines IoT technologies to improve the efficiency and sustainability of the garbage disposal process. The suggested SWM system includes sensor-equipped garbage bins that can monitor and transmit accurate information on their fill levels. Sensor-equipped garbage bins optimize waste disposal by providing real-time data, enhancing efficiency and providing timely predictions in trash management. Furthermore, the use of smart garbage bins helps the separation of various types of waste, increasing eco-friendly behaviors and helping recycling activities. The level indicators not only improve efficiency but also help to reduce environmental effects by lowering overflowing bins and eliminating waste. As a result, this research makes use of the architecture, functionality, and potential benefits of the IoT based SWM system, highlighting its role in supporting responsible waste management practices, resource conservation, and the development of urban areas. © 2024 IEEE.

关键词： Internet of things

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Domain generalization with semi-supervised learning for people-centric activity recognition

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science China(Information sciences) 2025年第1期68卷 171-188页

作者： Jing LIU Wei ZHU Di LI Xing HU Liang SONG Academy for Engineering & Technology Fudan University Shanghai East-bund Research Institute on Networking Systems of AI School of Optoelectronic Information and Computer Engineering University of Shanghai for Science & Technology

People-centric activity recognition is one of the most critical technologies in a wide range of real-world applications,including intelligent transportation systems, healthcare services, and brain-computer interfaces. Large-scale data collection and annotation make the application of machine learning algorithms prohibitively expensive when adapting to new tasks. One way of circumventing this limitation is to train the model in a semi-supervised learning manner that utilizes a percentage of unlabeled data to reduce the labeling burden in prediction tasks. Despite their appeal, these models often assume that labeled and unlabeled data come from similar distributions, which leads to the domain shift problem caused by the presence of distribution gaps. To address these limitations, we propose herein a novel method for people-centric activity recognition,called domain generalization with semi-supervised learning(DGSSL), that effectively enhances the representation learning and domain alignment capabilities of a model. We first design a new autoregressive discriminator for adversarial training between unlabeled and labeled source domains, extracting domain-specific features to reduce the distribution gaps. Second, we introduce two reconstruction tasks to capture the task-specific features to avoid losing information related to representation learning while maintaining task-specific consistency. Finally, benefiting from the collaborative optimization of these two tasks, the model can accurately predict both the domain and category labels of the source domains for the classification task. We conduct extensive experiments on three real-world sensing datasets. The experimental results show that DGSSL surpasses the three state-of-the-art methods with better performance and generalization.

关键词： activity recognition deep learning domain generalization semi-supervised learning adversarial training

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Detection and Classification of Indian Classical Bharathanatyam Mudras Using Enhanced Deep Learning Technique 3

Detection and Classification of Indian Classical Bharathanat...

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3rd International Conference on Innovations in science and technology for Sustainable Development, ICISTSD 2022

作者： Haridas, Sneha Ramani Bai, V. Vidya Academy of Science and Technology Dept. of Computer Science and Engineering Thrissur India Vidya Academy of Science and Technology Computer Science and Engineering Thrissur India

ISBN: (纸本)9781665499361

Indian Classical dance forms like bharathanatyam are composed of advanced hand gestures, facial expressions moreover as body moments. Because of its complexity, identifying each mudra in bharathanatyam is extremely difficult. This paper demonstrates a massive Convolutional Neural Network (CNN) that was trained on Google Colaboratory using a single step model, You Only Look Once version 3 (YOLOv3), to analyze images in the dataset and detect and classify the mudras. Open datasets of mudras are not presently available. So Bharatanatyam mudra dataset of single hand gesture images of 28 classes was created. This proposed system is, as far as we know, the first attempt in this subject. YOLOv3 was never used to detect mudras. YOLOv3 divides the image into sectors, predicts bounding boxes, and calculates probability for each. These bounding boxes are then weighted according to the projected probability, and the model is then able to detect the object based on the final weights. The neural network was able to correctly generate test data after being trained, with a mean average precision (mAP) of 73%. © 2022 IEEE.

关键词： Classification (of information)

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