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2023 International Conference on Informatics, Multimedia, Cyber and Information Systems, ICIMCIS 2023

作者： Nirwantono, Rudi Assidqi, Khoirunnisa Hidayat, Alam Ahmad Pebrianto Trinugroho, Joko Pardamean, Bens Bina Nusantara University Faculty of Engineering Bioinformatics and Data Science Research Center Biotechnology Department Jakarta11480 Indonesia Bina Nusantara University Faculty of Engineering Food Biotechnology Research Center Biotechnology Department Jakarta11480 Indonesia Bina Nusantara University School of Computer Science Bioinformatics and Data Science Research Center Mathematics Departement Jakarta11480 Indonesia Bina Nusantara University Bioinformatics and Data Science Research Center Jakarta11480 Indonesia Bina Nusantara University Binus Graduate Program - Computer Science Program Computer Science Department Jakarta11480 Indonesia

ISBN: (纸本)9798350307306

The infection of Plasmodium vivax is relatively less virulent than the deathliest Plasmodium falciparum. However, it still can lead to a fatal case and often induces recurring malaria due to dormant parasites in the liver. Thus, the research to study the drug to treat Plasmodium vivax is essential, where the enzyme dihydroorotate dehydrogenase (DHODH) has recently become a new drug target. However, the drug-enzyme interaction study has only recently been conducted in Plasmodium falciparum (pfDHODH) due to the lack of the 3D structure of enzyme DHODH from Plasmodium vivax that is crucial for the study. Therefore, this study aimed to perform the modelling study of Plasmodium vivax DHODH (PvDHODH) to create a 3D structure as a basis for drug-protein interaction study in upcoming studies. Sequence pvDHODH (Accession: SCO68359.1) was used in homology modelling using Modeller 10.2 with the crystal structure of DHODH from DHODH (Accession: 7KZY) as a template. Overall, the model generated from the homology modelling was considered a good model, and the 3D structure was close to the native state according to several parameters, including DOPE score, GA341 score, QMEAN4 value, 3D-1D score, ERRAT2 score, and ProSA score. Ramachandran plot also revealed that almost all amino acids were distributed in the desirable and allowed area (99.1%), and only 0.9% were in generously allowed regions. Superimposition of the model with the template also indicated that the model has an almost similar structure and amino acids positioning, including in the binding pocket and active site. Therefore, the model can be used for downstream analysis in drug-protein interaction studies. Nevertheless, some improvements can still be performed to upgrade the quality of the model by deleting unaligned residues on the C-terminal and realigning the residues at the doubting site. © 2023 IEEE.

关键词： Amino acids

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Style Change Detection using Discourse Markers

Style Change Detection using Discourse Markers

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2022 Conference and Labs of the Evaluation Forum, CLEF 2022

作者： Alvi, Faisal Algafri, Hasan Alqahtani, Naif Information & Computer Science Department King Fahd University of Petroleum and Minerals Dhahran Saudi Arabia Computer Science Program Dhanani School of Science and Engineering Habib University Karachi Pakistan

This article presents our approach for the Style Change Detection Task at PAN 2022 using discourse markers. Discourse markers (such as ‘what’, ‘I have’, etc.) are words or expressions used to connect, organise and manage conversations. We present two different approaches for Style Change Detection at PAN-2022. For Task 1, (Style Change Basic) our approach is based on identifying conversational patterns within the documents between a user and a possible respondent. Then, using classification algorithms, we predict the point of style change detection within each document. For Task 2 (Style Change Advanced) and Task 3 (Style Change Real World), we use an extensive list of frequently occurring discourse markers to identify the number of speakers as the number of authors within the document. This prediction serves as the number of clusters for text segments within the document. Subsequently, using unsupervised clustering we detect clusters of similar text segments such that each cluster comprises of text segment groups corresponding to each author. The resulting F1 scores for our approaches on the test set are: 0.70518 for Task 1, 0.32128 for Task 2 and 0.56360 for Task 3. © 2022 Copyright for this paper by its authors.

关键词： Change detection

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Evaluating Electrophysiological Responses due to Identity Judgments

Evaluating Electrophysiological Responses due to Identity Ju...

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IEEE Signal Processing and Communications Applications (SIU)

作者： Tuna Çakar Annette Hohenberger Computer Engineering MEF University Türkiye Institute of Cognitive Science Osnabrueck University Germany

ISBN: (数字)9798350388961

ISBN: (纸本)9798350388978

This study was conducted to explore how the brain processes decisions about identity, employing event-related potentials (ERPs) as a measure. The aim was to ascertain if the EEG/ERP technique could be used to monitor the cognitive processing of identity judgments as they happen. The investigation focused on comparing two groups of statements: those that used the concept of ‘same’ and those that used ‘different’. The researchers hypothesized that there would be notable differences in the ERPs, particularly around the 400 -millisecond mark, correlating with the reaction time disparities observed behaviorally. The ERP data revealed that the ‘different’ statements generated a unique N 400 response when contrasted with the ‘same’ statements, implying that the participants’ cognitive responses to these two types of judgments were not the same.

关键词： Signal processing Monitoring

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Using textile capacitive sensors to train synchronized movement of hands

Using textile capacitive sensors to train synchronized movem...

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2024 IEEE International Conference on Consumer Electronics, ICCE 2024

作者： Yang, Chang-Ming Wu, Shu-Cing Chen, Shih-Hung Wu, Ze-We Liao, Kuo-Cheng Chen, Chi-Chun Ming Young Biomedical Corp. Miaoli Taiwan National Chin-Yi University of Technology Program Prospective Technology of Electrical Engineering and Computer Science Taichung Taiwan National Chin-Yi University of Technology Dept. of Computer Science and Information Engineering Taichung Taiwan National Chin-Yi University of Technology Dept. of Electronic Engineering Taichung Taiwan

ISBN: (纸本)9798350324136

This study introduced a capacitive sensing interactive game platform aimed at promoting emotional stability, which we have named the 'Sunrise and Sunset' game. This game primarily consists of two pieces of regular textile fabric enveloping conductive silver fabric. A microcontroller was employed to extract the sensed capacitive values, and a game named 'Sunrise and Sunset' is designed to complement the slow raising and lowering of both hands. The development of this gaming platform has the potential to offer a novel method of emotional management, particularly in high-stress living environments. It can serve as an effective relaxation tool, aiding individuals in emotional balance, anxiety reduction, and stress alleviation. Simultaneously, this platform can contribute to the promotion of mental well-being, providing an engaging and beneficial means for people to manage their emotions and moods. © 2024 IEEE.

关键词： capacitive sensing emotional stability game relaxation tool silver fabric

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Improved IP lookup technology for trie-based data structures

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Journal of computer and System sciences 2023年 133卷 41-55页

作者： Lin, Yen-Heng Hsieh, Sun-Yuan Master Degree Program on Artificial Intelligence National Cheng Kung University Tainan701 Taiwan Department of Computer Science and Information Engineering Institute of Manufacturing Information Systems Institute of Medical Informatics National Cheng Kung University Tainan701 Taiwan Department of Computer Science and Information Engineering National Chi Nan University Nantou Puli Township54561 Taiwan

Many Internet protocol (IP) lookup algorithms have been formulated to improve network performance. This study reviewed and experimentally evaluated technologies for trie-based methods that reduce memory access, memory consumption and IP lookup time. Experiments involving binary tries (for simplicity) were conducted on four real-world data sets, two of which were on IPv4 router tables (855,997 and 876,489 active prefixes) and two of which were on IPv6 router tables (155,310 and 157,579 active prefixes). Technologies designed to reduce time taken (at the expense of memory consumption) worked well for IPv4, and those designed to reduce memory consumption worked well for IPv6. Various combinations of these technologies were applied together in the experiments. © 2022 Elsevier Inc.

关键词： Table lookup

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Validity and Reliability of Persian Version of Cyber-Bullying /Victimization Experience Questionnaire (CBVEQ) Among Iranian Adolescents

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International Journal of Bullying Prevention 2024年 1-12页

作者： Nooripour, Roghieh Hosseinian, Simin Ghanbari, Nikzad Wisniewski, Pamela Sikström, Sverker Department of Counseling Faculty of Education and Psychology Alzahra University Tehran Iran Faculty of Education and Psychology Shahid Beheshti University (SBU) Tehran Iran Department of Computer Science Faculty Fellow Flowers Family in Engineering Vanderbilt University Nashville United States Cognitive Psychology Chair of the Cognitive Division Department of Psychology Lund University Lund Sweden

This study aimed to measure validity and reliability of the Persian version of the Cyber-Bullying/Victimization Experience Questionnaire (CBVEQ) among Iranian adolescents. This cross-sectional validation study was conducted on Iranian adolescents between January 2022 and September 2022. Online questionnaires were completed by a total of 1439 Iranian high school students, with an age range of 14–18 years (M = 15.93 years, SD = 1.43). Participants completed Cyber-Bullying/Victimization Experience Questionnaire (CBVEQ), Online Disinhibition, Sensation Seeking, Empathy, and School Connectedness questionnaires. The validity and reliability of the CBVEQ were assessed through measures including Cronbach's alpha, construct validity via Confirmatory Factor Analysis (CFA), and evaluations of divergent and convergent validity. The CFA indicated that a two-factor model provides a good fit for the data: (_sbX² = 3011.31 (p < 0.01);SRMR = 0.06;CFI = 0.96;NFI = 0.96;IFI = 0.96;PNFI = 0.86;GFI = 0.83;RMSEA = 0.088). Cronbach’s alpha coefficient for the self-escapism was 0.89. There was a significant positive relationship between CBVEQ with online disinhibition (r = 0.47;P < 0.01) and sensation seeking (r = 0.44;P < 0.01). The finding showed significant negative relationship between CBVEQ score with school connectedness (SC) (r = -0.35;P < 0.01), and empathy (r = -0.42;P < 0.01). In addition, the findings have shown a relationship between CBVEQ and maternal educational status. Iranian researchers and specialists can use this scale for research or assessment purposes in Iranian adolescents to expand the existing knowledge about preventing and reducing cyberbullying. © The Author(s), under exclusive licence to Springer Nature Switzerland AG 2024.

关键词： Adolescent Cyber Bullying Cyber Victimization Measurement Validity

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Towards Explainability of Dimension Reduction Plots of Unsupervised Learning Model Outcomes 21

Towards Explainability of Dimension Reduction Plots of Unsup...

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21st IEEE Conference on Computational Intelligence in Bioinformatics and Computational Biology, CIBCB 2024

作者： Davila, Tony E. Astuhuaman Hier, Daniel B. Obafemi-Ajayi, Tayo Missouri State University Computer Science Dept. SpringfieldMO United States Missouri University of Science & Technology Kummer Institute RollaMO United States Missouri State University Engineering Program SpringfieldMO United States

ISBN: (纸本)9798350356632

Dimension reduction methods are used to visualize the output of unsupervised learning models when applied to complex data. These techniques improve interpretability by transforming a high-dimension space to a lower-dimension space (usually 2D or 3D). The results are typically viewed as 2D scatter plots, and class centroids may be added to increase interpretability. Although useful, the relationship of these class centroids to the underlying feature space remains opaque. The innovative aspect of this work is to create a strong link between the dimension-reduced space and the underlying high-dimension feature space by adding selected feature centroids to the 2D scatter plots. This approach simultaneously visualizes the centers for the classes and the features on the same 2D scatter plot. Since classes are often imbalanced, we provide a method to balance class sizes. We present an automated framework that performs a grid search to find the optimal dimension reduction parameters, balances the class sizes, uses an ensemble approach to find the most important features, and adds class centroids and selected feature centroids to 2D dimension-reduced plots. This is especially useful when applied to complex, feature-rich biomedical data, as addition of feature centroids to 2D scatter plots serve as landmarks for the previously featureless dimension-reduced space. The utility of this approach is demonstrated by its application to seven classes of neurogenetic diseases with 31 defining phenotypic features. © 2024 IEEE.

关键词： Unsupervised learning

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Cancer Prediction using Clinical and Genomic Data Fusion: A Systematic Review 6

Cancer Prediction using Clinical and Genomic Data Fusion: A ...

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6th International Conference on Cybernetics and Intelligent System, ICORIS 2024

作者： Julian, Kelvin Nugroho, Kuncahyo Setyo Nirwantono, Rudi Pardamean, Bens Computer Science Department BINUS Graduate Program Bina Nusantara University Jakarta Indonesia Bioinformatics and Data Science Research Center Bina Nusantara University Jakarta Indonesia Biotechnology Department Faculty of Engineering Bina Nusantara University Jakarta Indonesia

ISBN: (纸本)9798331539603

This systematic review provides a comprehensive overview of the methods used to integrate genomic and clinical data in cancer prediction. The review includes 19 studies across various cancers, including breast, colorectal, melanoma, lung, pancreatic, and thyroid. The studies employed different methods to combine genomic and clinical data, including weighted polygenic risk scores, genetic and non-genetic risk scores, and different machine learning algorithms. The results show significant improvements in model prediction performance accuracy across multiple studies. The review highlights the potential benefits of integrating genetic and phenotypic information to improve disease risk prediction models and inform personalized healthcare strategies. © 2024 IEEE.

关键词： Lung cancer

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Multi-view Transformer-Based Network for Prerequisite Learning in Concept Graphs 23rd

Multi-view Transformer-Based Network for Prerequisite Learn...

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23rd International Semantic Web Conference, ISWC 2024

作者： Wang, Zhichun Shao, Yifeng Peng, Boci Li, Bangui Li, Yun Wang, Qianren Li, Nijun School of Artificial Intelligence Beijing Normal University Beijing China Engineering Research Center of Intelligent Technology and Educational Application Ministry of Education Beijing China School of Intelligence Science and Technology Peking University Beijing China School of Computer Science and Engineering Beihang University Beijing China Advanced Cognitive AI Lab Shanghai Huawei Technologies Shanghai China

ISBN: (纸本)9783031778438

Prerequisite learning is the task of identifying prerequisite relations among concepts, which is important for many AI-based educational applications. Previous approaches explore different kinds of learning resources to obtain useful features for predicting prerequisites. Early approaches use handcrafted features while recent approaches use neural networks to encode information of concepts. To further improve the results of prerequisite learning, we build concept graphs to include comprehensive information about concepts from open data and learning resources, and propose a Multi-view Transformer-based Network (MTN) to encode multi-view features of concepts in the graph. Multi-view features are fused to make accurate predictions of concept prerequisites. We evaluate our approach on four public datasets and compare it with recently published approaches. The results show that our approach can achieve state-of-the-art results in the task of prerequisite learning. The source code and data are available at https://***/kg-bnu/MTN. © The Author(s), under exclusive license to Springer Nature Switzerland AG 2025.

关键词： Contrastive Learning

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Clustering Analysis of a Spatiotemporal Dataset with a Novel Kernel Density Estimator

Clustering Analysis of a Spatiotemporal Dataset with a Novel...

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2023 International Conference on Machine Learning and Cybernetics, ICMLC 2023

作者： Yu, Jen-Chien Yang, Chun-Chieh Gilbert, John Reuben Liu, Rou-Jun Oyang, Yen-Jen Yang, Meng-Han National Kaohsiung University of Science and Technology Department of Computer Science and Information Engineering Kaohsiung City807618 Taiwan National Taiwan University Master Program in Statistics Taipei106216 Taiwan National Taiwan University Department of Computer Science & Information Engineering Taiwan Graduate Institute of Biomedical Electronics and Bioinformatics National Taiwan University Taiwan

ISBN: (纸本)9798350303780

A vast number of spatiotemporal datasets collected from a wide range of sources has motivated scientists to develop effective approaches to identify interesting patterns hidden in these datasets. In this respect, kernel density estimators, which belong to a class of non-parametric estimators in statistics, have been widely exploited in recent years. With this background, we have developed a novel kernel density estimator aiming to provide accurate analysis results. According to the evaluation with a real spatiotemporal dataset, which collected emergency medical service records in a county in the United States, the proposed kernel density estimator can approximate the probability density function significantly more accurately than a conventional kernel density estimator. Furthermore, we have exploited the proposed kernel density estimator to identify interesting patterns hidden in the real spatiotemporal dataset. © 2023 IEEE.

关键词： Probability density function

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